Abstract: The disclosure provides a combination of one or more hydrolases and one or more anti-microorganism drugs, and a pharmaceutical composition or a kit comprising the combination. The disclosure also provides a method for treating a microorganism infection by using a therapeutically effective amount of the combination, pharmaceutical composition or kit. The combination of this disclosure is safer, and more economical, and can re-sensitize a drug against lots of bacteria at less dosage in clinical and avoid antimicrobial resistance to extend the lifespan of the drug.

Abstract: Disclosed is a three-dimensional deformation field modeling method fusing global navigation satellite system (GNSS)/synthetic aperture radar interferometry (InSAR) observation data. The three-dimensional deformation field modeling method includes: five parts of solving an InSAR line-of-sight velocity field, unifying a spatial reference datum of the GNSS data and the InSAR data, verifying precision of a result of the InSAR data, solving a three-dimensional deformation field having high precision based on a least square method, and analyzing and verifying a result. According to the method, the InSAR data is processed according to a high-precision time series method, a long-wavelength error of the InSAR data is corrected on the basis of a difference of two data spatial reference datums, and the accuracy of the result is ensured through verification of internal coincidence precision.

Abstract: The present invention provides a method to prepare polymer materials with interlocked porous structures by freezing and demulsification, which includes: (1) Preparing an emulsion containing uncrosslinked polymers and crosslinking agents. The uncrosslinked polymers are presented in the organic phase, and the crosslinking agents are presented in the organic phase or water phase. Under freezing, the demulsification is occurred which leads to the interaction between polymers and crosslinking agents, and the crosslinked materials are obtained. (2) After removing the ice crystals, polymer materials with interlocked porous structures are synthesized. The method provided by the present invention is simple to operate, and can well adjust the porous structures of obtained porous polymer materials. In addition, it is suitable for large scale manufacturing. At the same time, this process can form different functional porous polymer materials by simply changing the used monomers.

Abstract: The present invention discloses an acrylate oligomer, the acrylate oligomer is obtained by a reaction of isocyanate group-terminated oligomer and formate-terminated ethylene glycol methacrylate. After the acrylate oligomer provided by the present invention is photocured, the molecular structure, cross-linking density and other network structure characteristics of the acrylate oligomer can be changed through specific post-processing. Since the formate component formed after heat treatment has no water absorption and has a low glass transition temperature, the final material obtained after heat treatment has a lower water absorption rate and glass transition temperature. The present invention also provides a preparation method and an application method of the acrylate oligomer.

Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: The present disclosure provides a method, apparatus, medium and device for extracting a river drying-up region and frequency, and belongs to the technical field of remote sensing. The method for extracting a river drying-up region and frequency can be applied to efficiently acquiring river drying-up information for a long time within the large spatial region. With the inverse normalized difference water index (iNDWI) and the maximum value composite (MVC) method for the remote sensing images, the present disclosure omits the troublesome step of separately extracting a river range for each image in the conventional method. In addition, the present disclosure quickly obtains the drying-up frequency by counting the total number of available images and the number of non-water images at the same pixel position, and yields a greater efficiency for extracting the river drying-up region and frequency.

Abstract: The invention provides compounds of Formula (1): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: A capacitor sensor includes a first sensing channel and a second sensing channel. The first sensing channel operates in a first operation mode to obtain a first target sensing value. The first target sensing value is used to indicate a distance between a target object and a target metal segment. The second sensing channel operates in a second operation mode to obtain a second target sensing value. The second target sensing value is used to indicate a contact area between the target object and the target metal segment.

Abstract: An authentication system includes processing circuitry that is configured to receive an indication of a number of interconnected devices that are in communication with a user device, compare the number of interconnected devices that are in communication with the user device to a threshold, and grant access to an application on the user device in response to the number of interconnected devices meeting or exceeding the threshold.

Abstract: This invention provides compounds of Formula I wherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.

Abstract: A battery cell includes a housing; and a first electrode assembly group and a second electrode assembly group that are accommodated within the housing, where the first electrode assembly group and the second electrode assembly group are arranged along a first direction, the first electrode assembly group and the second electrode assembly group each include at least one electrode assembly, and electrode terminals of the first electrode assembly group and electrode terminals of the second electrode assembly group are respectively located on two walls of the housing that are disposed opposite along the first direction.

Abstract: A chip of a LED, comprising: a current blocking layer including a first current blocking layer grown along an epitaxial layer and a plurality of second current blocking layers disposed at one end of the first current blocking layer at intervals, the first current blocking layer gradually widens along a direction away from the second current blocking layers; a transparent conductive layer including a first transparent conductive layer and a second transparent conductive layer grown on the epitaxial layer, the first transparent conductive layer is grown on the current blocking layer and at least partially overlapped with the second current blocking layers; a metal finger electrode having a width gradually narrowed from the first end to the second end thereof and smaller than the width of the first current blocking layer, and the second current blocking layers are distributed around the first end of the metal finger electrode.

Abstract: Described herein is a metrology system and a method for converting metrology data via a trained machine learning (ML) model. The method includes accessing a first (MD1) SEM data set (e.g., images, contours, etc.) acquired by a first scanning electron metrology (SEM) system (TS1) and a second (MD2) SEM data set acquired by a second SEM system (TS2), where the first SEM data set and the second SEM data set being associated with a patterned substrate. Using the first SEM data set and the second SEM data set as training data, a machine learning (ML) model is trained (P303) such that the trained ML model is configured to convert (P307) a metrology data set (310) acquired (P305) by the second SEM system to a converted data set (311) having characteristics comparable to metrology data being acquired by the first SEM system. Furthermore, measurements may be determined based on the converted SEM data.

Abstract: A system uses a machine learning model trained using multitask learning for processing audio signals of different types. The system may be used in a device such as a headset, smart glasses, or a smart watch, and may be used to make predictions based on different types of audio signals, for example, for classifying acoustic events based on audio signal or for keyword spotting to detect wake words. The use of a single machine learning model for analyzing different types of audio signals improves storage efficiency as well as energy efficiency of devices compared to systems that use a different machine learning model for processing each type of audio signal.

Abstract: A magnetic field enhancing component, including: a first dielectric layer comprising a first surface and a second surface opposite to each other; a first electrode layer arranged on the first surface; a second electrode layer and a fourth electrode layer, which are arranged on the second surface at an interval, where orthographic projections of the first electrode layer and the second electrode layer, which are projected onto the first dielectric layer, overlap each other, and orthographic projections of the first electrode layer and the fourth electrode layer, which are projected onto the first dielectric layer, overlap each other; and a first external capacitor, a second external capacitor, and a first switching control circuit. One terminal of the second external capacitor is connected to the second electrode layer, and another terminal of the second external capacitor is connected to one terminal of the first external capacitor and one terminal of the first switching control circuit, respectively.

Abstract: Deformable structures, wearable devices, and wearable device usage methods are disclosed. The deformable structure may be used in the wearable device. The deformable structure includes a shape memory polymer. The shape memory polymer includes a functional group. The functional group is used to enable the shape memory polymer to change from a first state to a second state under a stimulation condition. At a first temperature, a Young's modulus of the shape memory polymer in the second state is greater than a Young's modulus of the shape memory polymer in the first state, and the first temperature is higher than a glass transition temperature of the shape memory polymer in the first state. When the deformable structure in the first state is used in the wearable device, the deformable structure may change into the second state to facilitate long-term wearing of the user.

Abstract: The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: An IGBT has a front-surface device region, an IGBT drift region, an IGBT buffer region, and an IGBT collector region that are sequentially connected. The front-surface device region may include a cell region, a field plate region, and a field limiting ring region. The IGBT drift region has a first-type doping element, the IGBT buffer region has a first-type doping element, and a concentration of the first-type doping element in the IGBT buffer region is greater than a concentration of the first-type doping element in the IGBT drift region. The IGBT collector region includes a cell collector region, a field plate collector region, and a field limiting ring collector region. The IGBT collector region has a second-type doping element, and a concentration of a second-type doping element in the cell collector region is greater than a concentration of a second-type doping element in the field plate collector region.

Abstract: Embodiments of the present invention provide a power semiconductor device, a related circuit, a chip, an electronic device, and a preparation method. The semiconductor device includes a first-conductivity-type first semiconductor layer, an insulated gate bipolar transistor (IGBT) comprising an IGBT region, and a diode comprising a diode region. The semiconductor device also includes a second-conductivity-type second semiconductor layer disposed on a first surface of the first semiconductor layer. A first-conductivity-type emitter region is disposed on a surface, of the second semiconductor layer located in the IGBT region, that faces away from the first semiconductor layer, and a collector layer and an electrode layer that are disposed under the second surface of the first semiconductor layer.