Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Abstract: Provided herein are compounds of the Formula (I): and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein R1, R2, R9, X1 and G are as defined herein, which are inhibitors of one or more TAM kinases and/or c-Met kinase, and are useful in the treatment and prevention of diseases which can be treated with a TAM kinase inhibitor and/or a c-Met kinase inhibitor.

Abstract: A lifting member for an elevator system is disclosed, including a rope formed from a plurality of strands comprising liquid crystal polymer fibers, with the strands extending along a length of the lifting member. A first polymer coating is disposed on outer surfaces of the fibers or on outer surfaces of the strands. A second polymer coating disposed over the first polymer coating.

Abstract: An anode plate for a film plating machine and a film plating machine are provided. The anode plate is formed by splicing a plurality of anode plate splicing units, and two adjacent anode plate splicing units are separated by an insulating medium. Each anode plate splicing unit is connected with a power supply. The anode plate is applicable to film plating machines of different breadth.

Abstract: The invention discloses a method for recycling and reusing polyurethane foam. The method includes: (1) The functionalized oligomers are obtained by adding solvent and catalyst to the polyurethane foam. (2) The functionalized oligomers are chemically modified, and the photosensitive group is introduced through the functional group reaction. The diluent, photoinitiator, and light absorber, etc. are introduced into the obtained oligomers to prepare photocurable resin. It can be used for photocurable coatings or 3D printing. This method has a fast reaction time, easy recovery of solvent and catalyst, higher value-added recycled product, good economic benefits, and social value.

Abstract: The present disclosure provides a method, apparatus, medium and device for extracting a river drying-up region and frequency, and belongs to the technical field of remote sensing. The method for extracting a river drying-up region and frequency can be applied to efficiently acquiring river drying-up information for a long time within the large spatial region. With the inverse normalized difference water index (iNDWI) and the maximum value composite (MVC) method for the remote sensing images, the present disclosure omits the troublesome step of separately extracting a river range for each image in the conventional method. In addition, the present disclosure quickly obtains the drying-up frequency by counting the total number of available images and the number of non-water images at the same pixel position, and yields a greater efficiency for extracting the river drying-up region and frequency.

Abstract: The present invention discloses an acrylate oligomer, the acrylate oligomer is obtained by a reaction of isocyanate group-terminated oligomer and formate-terminated ethylene glycol methacrylate. After the acrylate oligomer provided by the present invention is photocured, the molecular structure, cross-linking density and other network structure characteristics of the acrylate oligomer can be changed through specific post-processing. Since the formate component formed after heat treatment has no water absorption and has a low glass transition temperature, the final material obtained after heat treatment has a lower water absorption rate and glass transition temperature. The present invention also provides a preparation method and an application method of the acrylate oligomer.

Abstract: The present application discloses a method and device for generating a jacquard pattern, an electronic device. The method comprises: acquiring structure information of a unit structure of a preform to be prepared, wherein the structure information comprises a positional relationship between the warp yarns and the weft yarns of the unit structure of a preform to be prepared; obtaining a row number and a column number of the jacquard pattern to be generated, and correspondence between each pixel in the jacquard pattern to be generated and the warp yarns and weft yarns of the unit structure of the preform to be prepared, according to the structure information; and obtaining a pixel value of each pixel according to the correspondence and the positional relationship between the warp yarns and the weft yarns, and generating the jacquard pattern to be generated.

Abstract: A brucine gel formulation, a preparation method therefor and use thereof. Said gel formulation comprises 0.5%-1% of brucine, 0.5%-3% of a gel matrix and 10%-30% of a co-solvent. Said brucine hydrogel does not contain a transdermal enhancer, but has an excellent transdermal effect, is easy to coat, has good biosolubility, good skin absorption and good drug film adhesion, and is non-irritating to the skin and mucosa.

Abstract: A lifting member for an elevator system includes a rope formed from plurality of load carrying fibers extending along a length of the lifting member. The plurality of load carrying fibers including a plurality of aromatic polyester based fibers. A coating layer at least partially encapsulates the rope. An elevator system includes a hoistway, an elevator car disposed in the hoistway and movable therein, and a lifting member operably connected to the elevator car to suspend and/or drive the elevator car along the hoistway. The lifting member includes a rope formed from plurality of load carrying fibers extending along a length of the lifting member. The plurality of load carrying fibers including a plurality of aromatic polyester based fibers. A coating layer at least partially encapsulates the rope.

Abstract: Compounds that inhibit KRas G12D; in particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: The present invention provides a compound of Formula (I) including pharmaceutically acceptable salts thereof: (I) and therapeutic uses of these compounds. The invention further provides pharmaceutical compositions comprising these compounds, compositions comprising these compounds with a therapeutic co-agent, and methods of using the compounds and compositions to treat viral infections.

Abstract: Systems and methods for reducing prediction uncertainty in a prediction model associated with a patterning process are described. These may be used in calibrating a process model associated with the patterning process, for example. Reducing the uncertainty in the prediction model may include determining a prediction uncertainty parameter based on prediction data. The prediction data may be determined using the prediction model. The prediction model may have been calibrated with calibration data. The prediction uncertainty parameter may be associated with variation in the prediction data. Reducing the uncertainty in the prediction model may include selecting a subset of process data based on the prediction uncertainty parameter; and recalibrating the prediction model using the calibration data and the selected subset of the process data.

Abstract: A belt for an elevator system includes a plurality of tension members arranged along a belt width and extending longitudinally along a length of the belt, each tension member including a plurality of load carrying fibers, the plurality of load carrying fibers including a plurality of aromatic polyester based fibers. A jacket material at least partially encapsulates the plurality of tension members.

Abstract: Disclosed are the method, kit, system and use for screening or detecting or assisting in the diagnosis of bladder cancer, which are able to simultaneously detect FGFR3, TERT, PLEKHS1 point mutations and OTX1, NID2 and NRN1 methylation levels, thereby realizing the combined detection of gene point mutation and methylation, reducing the demand for samples, experimental operation steps and detection cycle, and improving the specificity and sensitivity of detection.

Abstract: A method and a device are used for generating a jacquard pattern of a preform. The method comprises acquiring initial structure information of a preform to be prepared; generating an initial jacquard pattern of the preform to be prepared; pixel values of pixels in the initial jacquard pattern, comprising a first pixel value and a second pixel value, are equal to the first pixel value when warp yarns corresponding to the pixels are located above corresponding weft yarns, and are equal to the second pixel value when warp yarns corresponding to the pixels are located below corresponding weft yarns; acquiring yarn reduction information of the preform to be prepared; and adjusting the initial jacquard pattern according to the yarn reduction information to obtain the jacquard pattern of the preform to be prepared.

Abstract: The invention discloses a preparation method of a catechol group modified biomacromolecular scaffold material, comprising: grafting a catechol-containing compound by amidation to obtain modified biomacromolecules; then, allowing dopamine to perform oxidized self-polymerization in a weakly alkaline buffer solution to form polydopamine (PDA) particles with a uniform particle size; next, forming a scaffold which has three cross-linking structures, namely modified biomacromolecules, modified biomacromolecules/PDA, and biomacromolecules/PDA, through interaction between catechol groups, interaction between catechol groups and PDA particles, and interaction between macromolecules and PDA particles in the modified macromolecules respectively; and cross-linking the scaffold with calcium ions, adipic dihydrazide or genipin to further adjust the degree of cross-linking and porosity of the scaffold.

Abstract: Embodiments of this disclosure provide a living object detection method and apparatus and electronic device. The apparatus includes a processor to calculate a distance matrix according to variance of Fourier transform amplitude values of radio signals received by a radio signal receiver within a determined period of time; and to calculate a distance between an object among objects and the radio signal receiver according to the distance matrix. According to this disclosure, a position of a living object among the objects may be detected based upon the distance in multiple scenarios.

Abstract: Provided are a heterocyclic derivative and an organic electroluminescent device thereof, which relates to the field of organic photoelectric materials. The heterocyclic derivative of Formula I has high electron mobility and great hole blocking performance, and thus the organic electroluminescent device prepared by using the heterocyclic derivative as the electron transport region material, especially the hole blocking material, has low drive voltage and high luminous efficiency. The organic electroluminescent device can also include a hole transport region, and the hole transport region, especially the emissive auxiliary layer, contains the triarylamine compound of Formula II. Since the electron transport region and the hole transport region of the device can effectively balance carriers, which reduces the quenching of excitons and improves the recombination probability of carriers, the device shows low drive voltage and high luminous efficiency.

Abstract: A monooxygenase having an amino acid sequence obtained by mutation of the amino acid sequence shown in SEQ ID NO:2 is disclosed. The use of the monooxygenase of the present invention in production of chiral sulfoxide-based drugs has advantages including mild reaction conditions, environmental friendliness, high yield, high optical purity of products, less peroxide products, and the like, and therefore the monooxygenase in the present invention has a good industrial application prospect in the production of proton pump inhibitors for the treatment of gastric ulcers.