Patents by Inventor Qiang Feng

Qiang Feng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250009656
    Abstract: Ultra pH sensitive (UPS) micelles encapsulating cytokines are provided that provide lower toxicity and higher efficacy compositions and methods for treating cancer with those compositions.
    Type: Application
    Filed: November 15, 2022
    Publication date: January 9, 2025
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Jinming GAO, Gang HUANG, Zhichen SUN, Qiang FENG, Wei LI
  • Patent number: 12109239
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: October 8, 2024
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza
  • Patent number: 12076347
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: September 3, 2024
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza
  • Patent number: 11786464
    Abstract: Described herein are therapeutic pH responsive compositions comprising a block copolymer and a therapeutic agent useful for the treatment of cancer.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: October 17, 2023
    Assignee: The Board of Regents of The University of Texas System
    Inventors: Jinming Gao, Tongyi Huang, Qiang Feng, Baran Sumer
  • Patent number: 11768976
    Abstract: The present disclosure belongs to the field of petroleum engineering, and specifically relates to a subsea Christmas tree re-prediction method integrating Kalman filter and Bayesian network. The subsea Christmas tree re-prediction method integrating Kalman filter and Bayesian network includes three steps: digital twin model establishment, degradation process re-prediction model establishment, and remaining useful life calculation model establishment.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: September 26, 2023
    Assignees: China University of Petroleum (East China), Ocean University of China, Beihang University
    Inventors: Baoping Cai, Yonghong Liu, Xiaoyan Shao, Guijie Liu, Qiang Feng, Qilin Wu, Weifeng Ge, Xincheng Li, Qibing Wu, Xiaolu Wu, Rui He, Zhexian Zou, Honghui Wang, Hongyan Fan
  • Patent number: 11609195
    Abstract: An experimentation method for a type I stress intensity factor test considering frost heaving force periodic changes, steps being 1: preparing a specimen, waterjet cutting on the specimen to simulate a non-penetrating rock mass fracture; step 2: vacuum saturating the specimen; step 3: affixing a strain gauge in a non-elastic area at a tip of the specimen; step 4: placing the specimen into a rock mass (1) fracture frost heaving experiment box (5), pressurizing by a pressurizing apparatus (4) balloons on either side of the frost heaving experiment box (5), shutting a valve and removing a pipe, placing the frost heaving experiment box (5) holding the specimen into a water tank, allowing water to immerse the specimen; and step 5: placing the water tank and the frost heaving experiment box (5) holding the specimen together into a high-low temperature alternating experiment box (7) to start a freeze-thaw cycle experiment.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: March 21, 2023
    Assignee: Shandong University of Science and Technology
    Inventors: Qiang Feng, Zedong Yang, Shuang Zhang, Jichao Jin, Weiwei Liu, Zhe Qin, Tingchun Li
  • Publication number: 20230028239
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Application
    Filed: May 24, 2022
    Publication date: January 26, 2023
    Applicant: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza
  • Publication number: 20230021393
    Abstract: The present disclosure belongs to the field of petroleum engineering, and specifically relates to a subsea Christmas tree re-prediction method integrating Kalman filter and Bayesian network. The subsea Christmas tree re-prediction method integrating Kalman filter and Bayesian network includes three steps: digital twin model establishment, degradation process re-prediction model establishment, and remaining useful life calculation model establishment.
    Type: Application
    Filed: November 5, 2021
    Publication date: January 26, 2023
    Applicants: China University of Petroleum (East China), Ocean University of China, Beihang University
    Inventors: Baoping Cai, Yonghong Liu, Xiaoyan Shao, Guijie Liu, Qiang Feng, Qilin Wu, Weifeng Ge, Xincheng Li, Qibing Wu, Xiaolu Wu, Rui He, Zhexian Zou, Honghui Wang, Hongyan Fan
  • Publication number: 20220381715
    Abstract: An experimentation method for a type I stress intensity factor test considering frost heaving force periodic changes, steps being 1: preparing a specimen, waterjet cutting on the specimen to simulate a non-penetrating rock mass fracture; step 2: vacuum saturating the specimen; step 3: affixing a strain gauge in a non-elastic area at a tip of the specimen; step 4: placing the specimen into a rock mass (1) fracture frost heaving experiment box (5), pressurizing by a pressurizing apparatus (4) balloons on either side of the frost heaving experiment box (5), shutting a valve and removing a pipe, placing the frost heaving experiment box (5) holding the specimen into a water tank, allowing water to immerse the specimen; and step 5: placing the water tank and the frost heaving experiment box (5) holding the specimen together into a high-low temperature alternating experiment box (7) to start a freeze-thaw cycle experiment.
    Type: Application
    Filed: April 21, 2021
    Publication date: December 1, 2022
    Inventors: Qiang FENG, Zedong YANG, Shuang ZHANG, Jichao JIN, Weiwei LIU, Zhe QIN, Tingchun LI
  • Patent number: 11484583
    Abstract: Provided is an application of Butyribacter intestini in the treatment and prevention of obesity-related diseases. Also provided is a composition for the treatment and prevention of obesity and obesity-related diseases.
    Type: Grant
    Filed: February 11, 2021
    Date of Patent: November 1, 2022
    Assignee: BGI SHENZHEN
    Inventors: Qiang Feng, Wenbin Xue, Yuanqiang Zou, Xiaoping Li, Chuan Liu, Xin Li
  • Patent number: 11473260
    Abstract: The present disclosure provides an effective stress cell for direct measurement of effective stress in saturated soil. The effective stress cell comprises a sensing diaphragm, a porous diaphragm, a connector and a strain sensor. The porous diaphragm allows pore-water to enter the interior space between the sensing diaphragm and the porous diaphragm to provide complete balance of pore-water pressures in the front and back of the sensing diaphragm. Thus, the effective stress cell can directly and accurately measure the effective stress in saturated soil using only one diaphragm at one location without measuring pore-water pressure.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: October 18, 2022
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Jian-Hua Yin, Jie-Qiong Qin, Wei-Qiang Feng
  • Patent number: 11400118
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: August 2, 2022
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza
  • Patent number: 11369638
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: June 28, 2022
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza
  • Publication number: 20210395684
    Abstract: Provided herein, in one aspect, is hematopoietic lineage cells such as natural killer cells generated in vitro from human pluripotent stem cells (hPSCs) that can be used as a cell source for therapeutics. Methods and compositions for making and using the same are also provided.
    Type: Application
    Filed: October 24, 2019
    Publication date: December 23, 2021
    Inventors: Qiang Feng, Miao-yun Zhang, Shi-jiang Lu
  • Publication number: 20210338579
    Abstract: Described herein are therapeutic pH responsive compositions comprising a block copolymer and a therapeutic agent useful for the treatment of cancer.
    Type: Application
    Filed: April 26, 2021
    Publication date: November 4, 2021
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Jinming GAO, Tongyi HUANG, Qiang FENG, Baran SUMER
  • Publication number: 20210299218
    Abstract: The present disclosure relates generally to biocompatible nanoparticles, and in particular, neuroprotective nanoparticles comprising ciliary neurotrophic factor and/or oncostatin M. Methods for making and using the same are also provided.
    Type: Application
    Filed: August 1, 2019
    Publication date: September 30, 2021
    Inventors: Qiang Feng, Gina Elsen, Po-Hsuen Chen, Shi-Jiang Lu
  • Patent number: 11053317
    Abstract: Disclosed is a pharmaceutical preparation comprising a CD147 monoclonal antibody, a buffer, a protein protectant and a surfactant. The pharmaceutical preparation can maintain the stability of the CD147 monoclonal antibody over a long period of time. Also disclosed are the use of the pharmaceutical preparation in the preparation of a drug for treating CD147-related diseases, in particular non-small cell lung cancer, and a method for preparing the pharmaceutical preparation.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: July 6, 2021
    Assignee: JIANGSU PACIFIC MEINUOKE BIO-PHARMACEUTICAL CO., LTD.
    Inventors: Hao Tang, Qiang Feng, Xiaochun Chen
  • Patent number: 11033614
    Abstract: Provided is an application of Butyribacter intestini in the treatment and prevention of obesity and obesity-related diseases. Also provided is a composition for the treatment and prevention of obesity and obesity-related diseases.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: June 15, 2021
    Assignee: BGI SHENZHEN
    Inventors: Qiang Feng, Wenbin Xue, Yuanqiang Zou, Xiaoping Li, Chuan Liu, Xin Li
  • Publication number: 20210170009
    Abstract: Provided is an application of Butyribacter intestini in the treatment and prevention of obesity-related diseases. Also provided is a composition for the treatment and prevention of obesity and obesity-related diseases.
    Type: Application
    Filed: February 11, 2021
    Publication date: June 10, 2021
    Inventors: Qiang Feng, Wenbin Xue, Yuanqiang Zou, Xiaoping Li, Chuan Liu, Xin Li
  • Publication number: 20210161964
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Application
    Filed: December 8, 2020
    Publication date: June 3, 2021
    Applicant: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza