Abstract: Biomarkers and methods related to microbiota for predicting the risk of a disease, particularly colorectal cancer (CRC), are described.

Abstract: Biomarkers and methods for predicting the risk of a disease related to microbiota, in particular colorectal cancer (CRC), are described.

Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.

Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.

Abstract: Biomarkers for diabetes and usages thereof are provided. And the biomarkers are nucleotides having polynucleotide sequences defined in SEQ ID NOs: 1-50.

Abstract: The present teachings relate to analysis of a sample including a plurality of species. In one example, sequences of fragments of polynucleotides of the sample are obtained. A reference set comprising a plurality of sequences is obtained. An initial bin for each of the plurality of sequences of the reference set is determined based on a relative abundance of each sequence of the reference set in the sample. At least one final bin is obtained by modifying the initial bins for the plurality of sequences based on a model.

Abstract: Biomarkers for diabetes and usages thereof are provided. And the biomarkers are Akkermansia muciniphila, Bacteroides intestinalis, Bacteroides sp. 20_3, Clostridium bolteae, Clostridium hathewayi, Clostridium ramosum, Clostridium sp. HGF2, Clostridium symbiosum, Desulfovibrio sp. 3_1_syn3, Eggerthella lenta, Escherichia coli, Clostridiales sp. SS3/4, Eubacterium rectale, Faecalibacterium prausnitzii, Haemophilus parainfluenzae, Roseburia intestinalis and Roseburia inulinivorans.

Abstract: The present invention provides use of Roseburia in the preparation of composition for prevention and/or treatment of obesity related diseases. Also provided are a composition used in the treatment and prevention for obesity related diseases, comprising pharmaceutical, drink, food, and/or animal feed composition, etc; and a method of reducing body weight and/or blood glucose.

Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.

Abstract: The present invention provides use of Roseburia in the preparation of composition for prevention and/or treatment of obesity related diseases. Also provided are a composition used in the treatment and prevention for obesity related diseases, comprising pharmaceutical, drink, food, and/or animal feed composition, etc; and a method of reducing body weight and/or blood glucose.

Abstract: A multi-level sliding sleeve including an outer cylinder, an inner sliding sleeve, a combined ball socket, a guider, an expander, an upper gland, a lower gland, and a ball. The outer cylinder includes internal threads in an upper end and external threads in a lower end, and the outer cylinder including an external wall including a plurality of drainage holes along the peripheral direction. The inner sliding sleeve is mounted to an inner wall of the outer cylinder through shear pins. The inner sliding sleeve includes a plurality of square holes in the middle along the peripheral direction, each of which is equipped with a ball socket inside. The ball sockets combine together to form a combined ball socket. The combined ball socket is equipped with the guider in the upper end and the expander in the lower end.

Abstract: The present invention discloses a structure of the waterproof tabletop for the touch panel, which includes: a tempered glass which is formed together containing an imaging part and a non-imaging part which are formed integrally; a film configured under the tempered glass corresponding to the imaging part and adhered to the tempered glass to form a projection screen; and a bracket configured under the tempered glass and adhered to the tempered glass to support the tempered glass.

Abstract: Nickel-based superalloys, for fabrication of monocrystalline turbine components to be used in industrial and aircraft turbine engines, having the following composition (in wt %): 5.6-8.1% Al, 4.1-14.1% Ru, 6.1-9.9% Ta, 3.6-7.5% Re, and the remaining balance Ni. The partitioning of alloying elements can be controlled to achieve a wide range of precipitate shapes and exceptional resistance to degradation under high temperature exposure conditions.