Patents by Inventor Qiang Ye

Qiang Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10092580
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with otic structure modulating compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: October 9, 2018
    Assignees: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
  • Publication number: 20180161271
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: September 20, 2017
    Publication date: June 14, 2018
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Publication number: 20180125781
    Abstract: Disclosed herein are methods for modulation of gel temperature of poloxamer-containing formulations. Also described herein are sustained release pharmaceutical formulations that gel upon contact with the body and are administered by direct application of these compositions and formulations onto or via perfusion into the targeted structure(s).
    Type: Application
    Filed: June 14, 2017
    Publication date: May 10, 2018
    Inventors: Qiang Ye, Luis A. Dellamary, Fabrice Piu
  • Publication number: 20180110727
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: June 2, 2017
    Publication date: April 26, 2018
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Michael Christopher Scaife, Benedikt Vollrath, Sergio G. Duron, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Publication number: 20180092926
    Abstract: The present invention is directed to compositions of bimatoprost, processes of preparing these compositions, devices comprising these compositions, and methods of lowering intraocular pressure.
    Type: Application
    Filed: October 4, 2017
    Publication date: April 5, 2018
    Inventors: Cary J. Reich, Carlos Schuler, Qiang Ye, Logan Stark, Rachna Jain
  • Patent number: 9904809
    Abstract: Aspects of a method and system for multi-level security initialization and configuration are provided. A security system may comprise a security processor, a host processor, and at least one security component, such as a descrambler. The security processor may enable a security component based on information stored within a non-volatile memory integrated within the security processor. The host processor may enable generation of at least one configuration command communicated to the security processor for configuring the enabled security component. The configuration command may correspond to a security control operational mode for the security component that may indicate, for example, activation or deactivation of the security component. The security processor may authenticate a digital signature in the configuration command. Initialization and configuration may be performed during a system boot sequence of the security system.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: February 27, 2018
    Assignee: Avago Technologies General IP (Singapore) Pte. Ltd.
    Inventors: Shee-Yen Tan, Xuemin Chen, Iue-Shuenn Chen, Qiang Ye
  • Publication number: 20180036231
    Abstract: Provided herein are methods for preventing and/or reducing the severity of drug induced ototoxicity. Provided herein are methods for recovery from hearing loss due to drug-induced ototoxicity.
    Type: Application
    Filed: October 19, 2017
    Publication date: February 8, 2018
    Inventors: Fabrice Piu, Qiang Ye, Luis Dellamary, Carl Lebel
  • Publication number: 20180016365
    Abstract: The present disclosure relates to tertiary amine co-initiators that demonstrate reduced leaching and which may be utilized in dental restoration and other biomedical applications. Embodiments of the present disclosure provide compounds and compositions for use in preparing polymers and light curable dental resin composites, as well as methods for preparing photocurable polymer-based dental restorative materials. In one or more disclosed embodiments, a co-initiator for use in preparing a polymer comprises a tertiary amine core and two or more pendant, terminal methacrylate groups. In some embodiments, the co-initiator may also act as a co-monomer in a co-polymerization reaction.
    Type: Application
    Filed: March 17, 2016
    Publication date: January 18, 2018
    Inventors: Xueping GE, Qiang YE, Paulette SPENCER, Jennifer Ann CHADWICK
  • Patent number: 9867778
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: January 16, 2018
    Assignees: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Patent number: 9808460
    Abstract: Disclosed herein are auris acceptable gel compositions containing a multiparticulate glutamate receptor antagonist, and methods for the treatment of otic diseases or conditions through intratympanic administration of the composition to an individual afflicted with an otic disease or condition.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: November 7, 2017
    Assignees: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Benedikt Vollrath, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Patent number: 9752613
    Abstract: A hook assembly includes a substrate having three tabs arranged in a triangular configuration, a hook including a pair of opposing side flaps, and a tripod mounting member configured to couple the hook to the substrate. The tripod mounting member includes three legs arranged in a triangular configuration, a pair of opposing side plates extending from two rear legs of the three legs, and a stopper groove. The three legs of the tripod mounting member correspond to the three tabs of the substrate. The hook assembly also includes a torsion spring having a pair of arms extending from opposite ends of the torsion spring, a first fastener configured to couple the tripod mounting member to the substrate, and a second fastener configured to extend through the side plates of the tripod mounting member and the side flaps of the hook to rotatably couple the hook to the tripod mounting member.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: September 5, 2017
    Assignee: Gardenia Industrial Limited
    Inventor: Qiang Ye Wen
  • Patent number: 9744126
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: August 29, 2017
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Patent number: 9603796
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: March 28, 2017
    Assignees: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Publication number: 20170027930
    Abstract: Disclosed herein are methods for the treatment of pediatric otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: September 13, 2016
    Publication date: February 2, 2017
    Inventors: Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel
  • Publication number: 20170000728
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: April 5, 2016
    Publication date: January 5, 2017
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Michael Christopher Scaife, Benedikt Vollrath, Sergio G. Duron, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Patent number: 9511020
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: December 6, 2016
    Assignees: Otonomy, Inc., The Regents of the University of California
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Patent number: 9486405
    Abstract: Disclosed herein are methods for the treatment of pediatric otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: November 8, 2016
    Assignee: OTONOMY, INC.
    Inventors: Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel
  • Publication number: 20160310415
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: June 16, 2016
    Publication date: October 27, 2016
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Michael Christopher Scaife, Benedikt Vollrath, Sergio G. Duron, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Patent number: 9427472
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Grant
    Filed: May 1, 2014
    Date of Patent: August 30, 2016
    Assignees: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Sergio G. Duron, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris
  • Publication number: 20160243028
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agents and auris pressure modulators. In these methods, the auris compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the immunomodulating and/or auris pressure modulating compositions and formulations onto the auris media and/or auris interna target areas, or via perfusion into the auris media and/or auris interna structures.
    Type: Application
    Filed: April 14, 2016
    Publication date: August 25, 2016
    Inventors: Jay Lichter, Andrew M. Trammel, Fabrice Piu, Qiang Ye, Michael Christopher Scaife, Benedikt Vollrath, Sergio G. Duron, Luis A. Dellamary, Carl Lebel, Jeffrey P. Harris