Patents by Inventor Qianqian Li
Qianqian Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20250101479Abstract: A plurality of terminal deoxynucleotidyl transferases (TdTs) and variants thereof are used for de novo synthesis of polynucleotides having controlled sequences and efficiently controllable synthesis of nucleic acid molecules without depending on a template. It is found that some amino acid residues in the TdT catalytic domain can be specifically modified to improve the ability of such modified TdTs to synthesize polynucleotides.Type: ApplicationFiled: January 13, 2023Publication date: March 27, 2025Inventors: Huifeng JIANG, Xiaoyun LU, Congyu LI, Jian CHENG, Lina LU, Qianqian LOU
-
Patent number: 12252414Abstract: The present disclosure discloses a method for preparing a ternary cathode precursor material with low sulfur content and high specific surface area, and belongs to the field of lithium ion battery materials. In the present disclosure, by using a continuous filter with a spraying device for concentrating a reaction material, sulfur impurities can be uniformly removed in a reaction stage, and neither are the reaction environment and the production efficiency affected, nor does introduction of new impurities occur. In addition, by removing the mother liquor by means of negative pressure suction filtration, the material can be oxidized uniformly in a controlled manner, and the specific surface area of the ternary cathode precursor material is uniformly increased, so that during sintering, lithium ions more easily enter the interior of particles of the ternary cathode precursor material, thus exerting a higher capacity.Type: GrantFiled: September 22, 2022Date of Patent: March 18, 2025Assignees: GUANGDONG BRUNP RECYCLING TECHNOLOGY CO., LTD., HUNAN BRUNP RECYCLING TECHNOLOGY CO., LTD.Inventors: Zhenqi Fang, Changdong Li, Genghao Liu, Dingshan Ruan, Qianqian Shi
-
Publication number: 20250079637Abstract: A includes a housing, an electrode assembly, and a first insulating member. The housing includes a first wall and a second wall disposed opposite each other in a first direction, where the first wall is provided with an electrode terminal. The electrode assembly is accommodated in the housing, where the electrode assembly is electrically connected to the electrode terminal, and the first wall supports the electrode assembly. The first insulating member abuts against an end of the electrode assembly facing the second wall. In the first direction, a gap is formed between a surface of the first insulating member facing away from the electrode assembly and an inner surface of the second wall.Type: ApplicationFiled: November 15, 2024Publication date: March 6, 2025Inventors: Wenlin ZHOU, Liangfan XU, Qianqian ZHANG, Quankun LI, Peng WANG
-
Publication number: 20250079652Abstract: A battery cell includes a housing, at least one electrode assembly and a support member. The housing has a wall part. The electrode assembly has a main body and at least one tab. In the first direction, the tab protrudes from an end of the main body facing the wall part. The tab includes a root part and a tab part, and the root part connects the main body and the tab part. The support member is provided at one side of the main body facing the wall part. The support member includes at least one wing part, and the tab part is bent around the wing part. The wing part is provided with an accommodation part, and the accommodation part is used to accommodate a portion of the root part.Type: ApplicationFiled: November 15, 2024Publication date: March 6, 2025Inventors: Liangfan XU, Wenlin ZHOU, Qianqian ZHANG, Xing LI, Quankun LI, Shaojun NIU, Haizu JIN
-
Publication number: 20250079584Abstract: A battery cell includes a casing, an electrode assembly, an end cover assembly and a support member. The casing has an opening. The electrode assembly has a main body and tabs protruding from the main body. The electrode assembly is accommodated in the casing. The end cover assembly covers the opening. The support member is located in the casing, and the tabs are bent around the support member. In the above, the support member is connected to the end cover assembly, to fix the support member. The battery cell is provided therein with the support member, and the tabs are bent around the support member. In addition, the support member is connected to the end cover assembly.Type: ApplicationFiled: November 15, 2024Publication date: March 6, 2025Inventors: Wenlin ZHOU, Liangfan XU, Qianqian ZHANG, Quankun LI, Peng WANG
-
Publication number: 20250064837Abstract: The present disclosure relates to compounds of formula (I) and their anti-tumor uses, and their intermediates of formula (III), and uses of the intermediates. The compound of formula (I) has a degrading effect on a specific target protein, which is mainly composed of three parts. The first part is a small molecule compound (SMBP, Small Molecules Binding Protein) that can bind to a protein, the second part LIN is a linker, and the three-part ULM is a ubiquitin ligand (ULM, Ubiquitin Ligase Binding Moiety), wherein SMBP is covalently bound to LIN, and LIN is covalently bound to ULM. A series of compounds designed and synthesized in the present disclosure have a wide range of pharmacological activities, including the functions of degrading specific proteins and/or inhibiting activities of specific proteins, and thus can be used in related tumor treatments.Type: ApplicationFiled: October 22, 2024Publication date: February 27, 2025Applicant: ShanghaiTech UniversityInventors: Xiaobao Yang, Biao Jiang, Renhong Sun, Chaowei Ren, Ning Sun, Ying Kong, Yan Li, Jinju Chen, Qianqian Yin, Xiaoling Song, Quanju Zhao, Xing Qiu
-
Patent number: 12238161Abstract: The invention belongs to the technical field of harmonic contribution evaluation, and particularly relates to a system for tracing harmonic sources based on a cloud-edge-terminal collaboration and a method thereof, comprising: terminal module, collecting and transmitting real-time harmonic data to edge module; edge module, comprising plurality of edge computing servers deployed for the transformer substations and the transformer districts by units, realizing hierarchical control between edge computing servers according to voltage levels, and transmitting harmonic sources tracing task through hierarchical interactions between the edge computing servers; the edge computing server receiving harmonic sources tracing service request performs the tracing task, and feeds tracing result back to central module; and, central module, comprising cloud server receiving harmonic sources tracing service request initiated by user, determining edge computing server offloaded by the request, storing final tracing result from eType: GrantFiled: August 28, 2024Date of Patent: February 25, 2025Assignee: SHANDONG UNIVERSITYInventors: Yuanyuan Sun, Lei Ding, Qingshen Xu, Yahui Li, Quanrui Hao, Kaiqi Sun, Shulin Yin, Bowen Li, Ruize Sun, Pengbo Shan, Demin Qi, Qianqian Li
-
Patent number: 12226424Abstract: The present disclosure relates to compounds of formula (I) and their anti-tumor uses, and their intermediates of formula (III), intermediates of formula (IV), and uses of the intermediates. The compound of formula (I) has a degrading effect on a specific target protein, which is mainly composed of three parts. The first part is a small molecule compound (SMBP, Small Molecules Binding Protein) that can bind to a protein, the second part LIN is a linker, and the three-part ULM is a ubiquitin ligand (ULM, Ubiquitin Ligase Binding Moiety), wherein SMBP is covalently bound to LIN, and LIN is covalently bound to ULM. A series of compounds designed and synthesized in the present disclosure have a wide range of pharmacological activities, including the functions of degrading specific proteins and/or inhibiting activities of specific proteins, and thus can be used in related tumor treatments.Type: GrantFiled: April 9, 2019Date of Patent: February 18, 2025Assignee: ShanghaiTech UniversityInventors: Xiaobao Yang, Biao Jiang, Renhong Sun, Chaowei Ren, Ning Sun, Ying Kong, Yan Li, Jinju Chen, Qianqian Yin, Xiaoling Song, Quanju Zhao, Xing Qiu
-
Publication number: 20250054441Abstract: A pixel driving circuit (100) includes a photosensitive device (110) and a dimming sub-circuit (120) connected between a first voltage terminal (VDD) and a light-emitting device (200). A first terminal of the photosensitive device (110) is configured to receive a control signal, a second terminal of the photosensitive device (110) is electrically connected to a first node (N1), and the photosensitive device (110) is configured to adjust a voltage at the first node (N1) based on the control signal. The dimming sub-circuit (120) is electrically connected to the first node (N1). The on-state of the dimming sub-circuit (120) changes with a change of the voltage at the first node (N1), and the dimming sub-circuit (120) is configured to adjust brightness of the light-emitting device (200) based on a first voltage signal from the first voltage terminal (VDD) under control of the voltage at the first node (N1).Type: ApplicationFiled: April 18, 2023Publication date: February 13, 2025Applicants: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Shengyi LI, Haitao CHENG, Qianqian LIU, Jing CHEN, Xin BI
-
Patent number: 12220464Abstract: The present invention relates to novel linkers containing a 2,3-disubstituted succinic group, or 2-monosubstituted, or 2,3-disubstituted fumaric or maleic (trans (E)- or cis (Z)-butenedioic), or acetylenedicarboxyl group for conjugation of a cytotoxic agent, and/or one or more different functional molecules per linker to a cell-binding molecule, through bridge linking pairs of thiols on the cell-binding molecule specifically. The invention also relates to methods of making such linkers, and of using such linkers in making homogeneous conjugates, as well as of application of the conjugates in treatment of cancers, infections and autoimmune disorders.Type: GrantFiled: June 23, 2021Date of Patent: February 11, 2025Assignee: Hangzhou DAC Biotech Co., Ltd.Inventors: Robert Yongxin Zhao, Qingliang Yang, Yuanyuan Huang, Shun Gai, Linyao Zhao, Hangbo Ye, Huihui Guo, Qianqian Tong, Minjun Cao, Junxiang Jia, Chengyu Yang, Wenjun Li, Xiaomai Zhou, Hongsheng Xie, Chen Lin, Zhixiang Guo, Zhicang Ye
-
Publication number: 20250038726Abstract: Described herein is a method of performing content-aware audio processing for an audio signal comprising a plurality of audio components of different types. The method includes source separating the audio signal into at least a voice-related audio component and a residual audio component. The method further includes determining a dynamic audio gain based on the voice-related audio component and the residual audio component. The method also includes performing audio level adjustment for the audio signal based on the determined audio gain. Further described are corresponding apparatus, programs, and computer-readable storage media.Type: ApplicationFiled: November 3, 2022Publication date: January 30, 2025Applicant: Dolby Laboratories Licensing CorporationInventors: Shaofan YANG, Kai LI, Qianqian FANG
-
Publication number: 20240428834Abstract: Each Stop Read Go (SRG) setting has different latency and reliability issues. An aspect of the present disclosure is related to minimizing these reliability risks while maintaining the benefit of low suspend latency when implementing SRG.Type: ApplicationFiled: August 7, 2023Publication date: December 26, 2024Applicant: Western Digital Technologies, Inc.Inventors: Jing Fu, Weikai Xu, Qianqian Li, Sumner Xia
-
Publication number: 20240422213Abstract: The invention belongs to the technical field of harmonic contribution evaluation, and particularly relates to a system for tracing harmonic sources based on a cloud-edge-terminal collaboration and a method thereof, comprising: terminal module, collecting and transmitting real-time harmonic data to edge module; edge module, comprising plurality of edge computing servers deployed for the transformer substations and the transformer districts by units, realizing hierarchical control between edge computing servers according to voltage levels, and transmitting harmonic sources tracing task through hierarchical interactions between the edge computing servers; the edge computing server receiving harmonic sources tracing service request performs the tracing task, and feeds tracing result back to central module; and, central module, comprising cloud server receiving harmonic sources tracing service request initiated by user, determining edge computing server offloaded by the request, storing final tracing result from eType: ApplicationFiled: August 28, 2024Publication date: December 19, 2024Inventors: Yuanyuan SUN, Lei Ding, Qingshen Xu, Yahui Li, Quanrui Hao, Kaiqi Sun, Shulin Yin, Bowen Li, Ruize Sun, Pengbo Shan, Demin Qi, Qianqian Li
-
Publication number: 20240409729Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise a non-crosslinked elastomer, oil, and polyethylene. The oil may be from about 15 wt. % to about 60 wt. % oil. The polyethylene may be from about 0.1 wt. % to about 40 wt. %.Type: ApplicationFiled: May 7, 2024Publication date: December 12, 2024Applicant: GEON Performance Solutions, LLCInventors: Yun Martin Lu, Xin Zhang, Xiaofeng Zheng, Qianqian Li
-
Patent number: 12163015Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise a non-crosslinked elastomer, oil, polyethylene, and anti-oxidant. The oil may be from about 15 wt. % to about 50 wt. % oil. The polyethylene may be from about 3 wt. % to about 30 wt. %. The anti-oxidant may be from about 0 to about 0.5 wt. %.Type: GrantFiled: August 16, 2022Date of Patent: December 10, 2024Assignee: GEON Performance Solutions, LLCInventors: Yun Martin Lu, Xin Zhang, Xiaofeng Zheng, Qianqian Li
-
Publication number: 20230265268Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise at least one bio based component of: a non-crosslinked elastomer, softener, polyethylene, and polar polymer. The softener may be from about 15 wt. % to about 50 wt. % softener. The polyethylene may be from about 3 wt. % to about 30 wt. %. The polar polymer may be from about 3.0 to about 15 wt. %.Type: ApplicationFiled: April 7, 2023Publication date: August 24, 2023Inventors: Yun Martin LU, Xin ZHANG, Xiaofeng ZHENG, Qianqian LI
-
Publication number: 20230227635Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise a non-crosslinked elastomer, oil, polyethylene, and anti-oxidant. The oil may be from about 15 wt. % to about 50 wt. % oil. The polyethylene may be from about 3 wt. % to about 30 wt. %. The anti-oxidant may be from about 0 to about 0.5 wt. %.Type: ApplicationFiled: August 16, 2022Publication date: July 20, 2023Inventors: Yun Martin Lu, Xin Zhang, Xiaofeng Zheng, Qianqian Li
-
Patent number: 11685903Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.Type: GrantFiled: April 15, 2020Date of Patent: June 27, 2023Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li
-
Publication number: 20230181685Abstract: Compositions and methods are provided according to aspects of the present disclosure for inhibition of a pathogenic virus. According to particular aspects, compositions and methods of the present disclosure include degradation of pathogenic viral nucleic acids by interferon-stimulated gene 20-kDa protein (ISG20) and/or a variant thereof, administered to a cell and/or subject to inhibit a pathogenic viral infection of the cell and/or a subject. Compositions and methods are provided according to aspects of the present disclosure wherein providing the ISG20 protein, or a variant thereof, comprises administering a therapeutically effective amount of the ISG20 protein and/or variant, to a subject having, or at risk of having, a viral infection.Type: ApplicationFiled: May 10, 2021Publication date: June 15, 2023Inventors: Gil MOR, Jiahui DING, Qianqian LI, Jianjun WANG
-
Publication number: 20230133255Abstract: A quasi-macroscopic cold field emission electron gun and a manufacturing method thereof are provided, which includes a filament device and an electron gun base, wherein the filament device includes a cold cathode filament and a conductive capillary tube, the cold cathode filament passes through one end of the conductive capillary tube and is crimped through a pressing groove device, the other end of the conductive capillary tube is connected to the electron gun base, and the end of the cold cathode filament is the electron emission end. Through the coaxial nesting and pressing deformation of quasi-macroscopic carbon fiber and metal tube and using of the non welding electrical connection method, this technology avoids the problem that it is not easy to form a reliable electrical connection during the welding process due to the poor wettability between carbon fiber and metal.Type: ApplicationFiled: October 27, 2022Publication date: May 4, 2023Inventors: Fanguang ZENG, Yan LI, Huali MA, Peng YANG, Mingyu LI, Yajuan ZHENG, Zhen YAN, Ming JIANG, Mengyuan ZHAO, Zihua DONG, Qianqian LI, Weichao MA, Zhaojun TANG, Kun XU, Linjie FU