Patents by Inventor Qianqian Li
Qianqian Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11938567Abstract: A laser fusion welding device includes a 1.9 ?m laser light source, a control unit and a light spot adjusting device. The control unit is configured to control the laser light source and the light spot adjusting device to adjust a laser power density at an object to be subjected to fusion welding. The 1.9 ?m laser light source has output power of 100-500 W. The control unit includes a time control unit, a power control unit and a light spot control unit. The time control unit is configured to control a turn-on time of the laser light source. The power control unit is configured to control the output power of the laser light source. The light spot control unit is configured to control the light spot adjusting device to adjust a size of a light spot at the object to be subjected to fusion welding.Type: GrantFiled: July 11, 2023Date of Patent: March 26, 2024Assignee: XINJIANG TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY, CHINESE ACADEMY OF SCIENCESInventors: Linjun Li, Shilie Pan, Xiaoming Duan, Yu Zhou, Yingjie Shen, Qianqian Hao, Yuqiang Yang, Xin He
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Publication number: 20230265268Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise at least one bio based component of: a non-crosslinked elastomer, softener, polyethylene, and polar polymer. The softener may be from about 15 wt. % to about 50 wt. % softener. The polyethylene may be from about 3 wt. % to about 30 wt. %. The polar polymer may be from about 3.0 to about 15 wt. %.Type: ApplicationFiled: April 7, 2023Publication date: August 24, 2023Inventors: Yun Martin LU, Xin ZHANG, Xiaofeng ZHENG, Qianqian LI
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Publication number: 20230227635Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise a non-crosslinked elastomer, oil, polyethylene, and anti-oxidant. The oil may be from about 15 wt. % to about 50 wt. % oil. The polyethylene may be from about 3 wt. % to about 30 wt. %. The anti-oxidant may be from about 0 to about 0.5 wt. %.Type: ApplicationFiled: August 16, 2022Publication date: July 20, 2023Inventors: Yun Martin Lu, Xin Zhang, Xiaofeng Zheng, Qianqian Li
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Patent number: 11685903Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.Type: GrantFiled: April 15, 2020Date of Patent: June 27, 2023Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li
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Publication number: 20230181685Abstract: Compositions and methods are provided according to aspects of the present disclosure for inhibition of a pathogenic virus. According to particular aspects, compositions and methods of the present disclosure include degradation of pathogenic viral nucleic acids by interferon-stimulated gene 20-kDa protein (ISG20) and/or a variant thereof, administered to a cell and/or subject to inhibit a pathogenic viral infection of the cell and/or a subject. Compositions and methods are provided according to aspects of the present disclosure wherein providing the ISG20 protein, or a variant thereof, comprises administering a therapeutically effective amount of the ISG20 protein and/or variant, to a subject having, or at risk of having, a viral infection.Type: ApplicationFiled: May 10, 2021Publication date: June 15, 2023Inventors: Gil MOR, Jiahui DING, Qianqian LI, Jianjun WANG
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Publication number: 20230133255Abstract: A quasi-macroscopic cold field emission electron gun and a manufacturing method thereof are provided, which includes a filament device and an electron gun base, wherein the filament device includes a cold cathode filament and a conductive capillary tube, the cold cathode filament passes through one end of the conductive capillary tube and is crimped through a pressing groove device, the other end of the conductive capillary tube is connected to the electron gun base, and the end of the cold cathode filament is the electron emission end. Through the coaxial nesting and pressing deformation of quasi-macroscopic carbon fiber and metal tube and using of the non welding electrical connection method, this technology avoids the problem that it is not easy to form a reliable electrical connection during the welding process due to the poor wettability between carbon fiber and metal.Type: ApplicationFiled: October 27, 2022Publication date: May 4, 2023Inventors: Fanguang ZENG, Yan LI, Huali MA, Peng YANG, Mingyu LI, Yajuan ZHENG, Zhen YAN, Ming JIANG, Mengyuan ZHAO, Zihua DONG, Qianqian LI, Weichao MA, Zhaojun TANG, Kun XU, Linjie FU
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Publication number: 20220370538Abstract: A method for extracting functional ingredients of mulberry leaves using enzyme is provided. A method for preparing crude cellulase enzyme solution and crude pectinase enzyme solution includes: preparing PDA slant culture mediums; preparing fermentation mediums for producing cellulase and pectinase; preparing solid bacteria; fermentation; preparing crude cellulase enzyme solution and crude pectinase enzyme solution. A preparation method of mulberry leaf concentrate is provided and includes: enzymatic hydrolysis, enzyme inactivation and concentration. A method for preparing mulberry leaf products from mulberry leaf concentrate is provided.Type: ApplicationFiled: December 15, 2021Publication date: November 24, 2022Inventors: Lin Hao, Qianqian Li, Liping Hao
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Patent number: 11498992Abstract: The present invention provides an aqueous paint composition comprising by dry weight based on total dry weight of the pigment composition, from 11% to 35% of a polymeric duller of (co)polymeric particles having an average diameter of from 1 to 20 ?m, and from 25% to 70% of titanium dioxide particles; wherein from 50% to 100% of the titanium dioxide particles are encapsulated by polymer shell of (co)polymeric particles.Type: GrantFiled: April 28, 2015Date of Patent: November 15, 2022Assignees: Dow Global Technologies LLC, Rohm and Has CompanyInventors: Junyu Chen, Wei Cui, Tao Wang, Tao Wang, Qianqian Li, Juan Li, Longlan Cui, David G. Speece, Jr.
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Patent number: 11447619Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise a non-crosslinked elastomer, oil, polyethylene, and antioxidant. The oil may be from about 15 wt. % to about 50 wt. % oil. The polyethylene may be from about 3 wt. % to about 30 wt. %. The antioxidant may be from about 0 to about 0.5 wt. %.Type: GrantFiled: April 22, 2020Date of Patent: September 20, 2022Assignee: POLYMAX TPE LLCInventors: Yun Martin Lu, Xin Zhang, Xiaofeng Zheng, Qianqian Li
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Patent number: 11231652Abstract: Disclosed is a liquid chemical vapor recovery device, a wet stripping device, a photoresist stripping process and a method for manufacturing a thin film transistor-liquid crystal display using the same. The liquid chemical vapor recovery device comprises: an exhaust pipe for discharging a gas in a processing chamber for wet processing with a liquid chemical, the gas comprising a vapor of the liquid chemical; and a reflux pipe for refluxing the liquid chemical condensed in the exhaust pipe to a liquid chemical storage tank, the reflux pipe having an inlet connected to the exhaust pipe and an outlet connected to the liquid chemical storage tank, wherein, at least a part of the exhaust pipe positioned upstream of the inlet of the reflux pipe is formed as a pipe segment with a rugged inner surface.Type: GrantFiled: April 13, 2018Date of Patent: January 25, 2022Assignees: BOE TECHNOLOGY GROUP CO., LTD., HEFEI XINSHENG OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Qianqian Li, Shikai Wang, Dongseob Kim, Jun Geng, Yadong Liang, Xiaoning Liu, Mingming Wang, Hao Yin, Yadong Xu, Zhongren Jiang
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Patent number: 11154584Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.Type: GrantFiled: July 22, 2019Date of Patent: October 26, 2021Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li
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Patent number: 11060500Abstract: The present invention discloses a ducted bidirectional tidal current power station system, mainly consisting of a bidirectional tidal current power generation device, a dam, an open sea, an inland sea, a duct, and an opening/closing gate. The bidirectional tidal current power generation device is installed in the duct on the bottom of the dam. Openings, respectively communicated with the open sea and the inland sea, are formed at two ends of the duct, and an opening/closing gate is arranged at each of the two openings. By the ducted bidirectional tidal current power station system of the present invention, the cost of marine construction, operation and maintenance of the tidal current power generation device in an open sea area is saved, and the complex structure of the power generation device in the tidal power station and the cost of strict construction of auxiliary devices and runners are avoided.Type: GrantFiled: August 30, 2019Date of Patent: July 13, 2021Assignee: HangZhou JiangHe Hydro-Electrical Sci. & Tech. Co.Inventors: Liwei Chen, Changlu Liu, Jianfeng Yu, Dongli Zhang, Yinhua Chen, Qianqian Li, Yujuan Wang, Jinbo Hu
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Publication number: 20200332096Abstract: A thermoplastic elastomer composition and method of making the thermoplastic elastomer are disclosed. The thermoplastic elastomer may comprise a polymer blend. The polymer bland may comprise a non-crosslinked elastomer, oil, polyethylene, and antioxidant. The oil may be from about 15 wt. % to about 50 wt, % oil. The polyethylene may be from about 3 wt. % to about 30 wt. %. The antioxidant may be from about 0 to about 0.5 wt. %.Type: ApplicationFiled: April 22, 2020Publication date: October 22, 2020Inventors: Yun Martin Lu, Xin Zhang, Xiaofeng Zheng, Qianqian Li
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Publication number: 20200291362Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.Type: ApplicationFiled: April 15, 2020Publication date: September 17, 2020Inventors: Jianjun Wang, Qianqian Li
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Patent number: 10640751Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPS cells formed using this method and uses thereof.Type: GrantFiled: February 8, 2019Date of Patent: May 5, 2020Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li
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Patent number: 10643866Abstract: The present disclosure provides a wet etching machine and an etching method. The wet etching machine including an etching chamber in which at least two etching layers are disposed. The etching layers are successively overlapped with each other from up to down, and each etching layer includes a first transfer carrier for receiving and transferring a substrate to be etched and a spraying apparatus disposed right above the first transfer carrier for spraying etching solution. When the total etching time is needed to be longer than the transfer time of the substrate without stopping the substrate, the present disclosure can solve the problems in the prior art of causing the takt time decreased due to the stopping time of the substrate is required to be increased or causing the area of the facility increased due to the number of the etching chambers connected in series is required to be increased.Type: GrantFiled: April 21, 2016Date of Patent: May 5, 2020Assignees: BOE TECHNOLOGY GROUP CO., LTD., HEFEI XINSHENG OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Shengrong Li, Jaeyun Jung, Shikai Wang, Dongseob Kim, Jun Geng, Dengtao Li, Qianqian Li, Yadong Liang
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Publication number: 20200132041Abstract: The present invention discloses a ducted bidirectional tidal current power station system, mainly consisting of a bidirectional tidal current power generation device, a dam, an open sea, an inland sea, a duct, and an opening/closing gate. The bidirectional tidal current power generation device is installed in the duct on the bottom of the dam. Openings, respectively communicated with the open sea and the inland sea, are formed at two ends of the duct, and an opening/closing gate is arranged at each of the two openings. By the ducted bidirectional tidal current power station system of the present invention, the cost of marine construction, operation and maintenance of the tidal current power generation device in an open sea area is saved, and the complex structure of the power generation device in the tidal power station and the cost of strict construction of auxiliary devices and runners are avoided.Type: ApplicationFiled: August 30, 2019Publication date: April 30, 2020Inventors: Liwei CHEN, Changlu LIU, Jianfeng YU, Dongli ZHANG, Yinhua CHEN, Qianqian LI, Yujuan WANG, Jinbo HU
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Patent number: 10634784Abstract: A device and a method for detecting main acoustic indexes of multi-beam sonar pertaining to the field of hydrographic surveying and charting technology. The device includes a rotating device and a lifting gear installed in an anechoic tank. The bottom of the rotating device is equipped with a multi-beam sonar that has its rotating plane perpendicular to the direction of track line and transmits signals along the horizontal direction. A standard hydrophone is equipped at the bottom of the lifting gear, and is connected with a signal collector. The device utilizes the standard hydrophone to receive the pulse signals transmitted by the multi-beam sonar and employs the multi-beam sonar to receive the standard sound source signals, designs the detection process for data collection for analysis and research, thereby achieving the detection of the frequency, source level and beam angle of multi-beam sonar.Type: GrantFiled: January 16, 2018Date of Patent: April 28, 2020Assignee: SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Fanlin Yang, Xiankun Wang, Donghui Li, Qianqian Li, Bo Shi, Dong Jing, Xiushan Lu, Xiaodong Cui
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Patent number: 10548983Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.Type: GrantFiled: September 4, 2018Date of Patent: February 4, 2020Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
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Publication number: 20190336562Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.Type: ApplicationFiled: July 22, 2019Publication date: November 7, 2019Inventors: Jianjun Wang, Qianqian Li