Patents by Inventor Qianqian Li

Qianqian Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200132041
    Abstract: The present invention discloses a ducted bidirectional tidal current power station system, mainly consisting of a bidirectional tidal current power generation device, a dam, an open sea, an inland sea, a duct, and an opening/closing gate. The bidirectional tidal current power generation device is installed in the duct on the bottom of the dam. Openings, respectively communicated with the open sea and the inland sea, are formed at two ends of the duct, and an opening/closing gate is arranged at each of the two openings. By the ducted bidirectional tidal current power station system of the present invention, the cost of marine construction, operation and maintenance of the tidal current power generation device in an open sea area is saved, and the complex structure of the power generation device in the tidal power station and the cost of strict construction of auxiliary devices and runners are avoided.
    Type: Application
    Filed: August 30, 2019
    Publication date: April 30, 2020
    Inventors: Liwei CHEN, Changlu LIU, Jianfeng YU, Dongli ZHANG, Yinhua CHEN, Qianqian LI, Yujuan WANG, Jinbo HU
  • Patent number: 10634784
    Abstract: A device and a method for detecting main acoustic indexes of multi-beam sonar pertaining to the field of hydrographic surveying and charting technology. The device includes a rotating device and a lifting gear installed in an anechoic tank. The bottom of the rotating device is equipped with a multi-beam sonar that has its rotating plane perpendicular to the direction of track line and transmits signals along the horizontal direction. A standard hydrophone is equipped at the bottom of the lifting gear, and is connected with a signal collector. The device utilizes the standard hydrophone to receive the pulse signals transmitted by the multi-beam sonar and employs the multi-beam sonar to receive the standard sound source signals, designs the detection process for data collection for analysis and research, thereby achieving the detection of the frequency, source level and beam angle of multi-beam sonar.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: April 28, 2020
    Assignee: SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Fanlin Yang, Xiankun Wang, Donghui Li, Qianqian Li, Bo Shi, Dong Jing, Xiushan Lu, Xiaodong Cui
  • Patent number: 10548983
    Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: February 4, 2020
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
  • Publication number: 20190336562
    Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 7, 2019
    Inventors: Jianjun Wang, Qianqian Li
  • Patent number: 10357532
    Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: July 23, 2019
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li
  • Publication number: 20190161739
    Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.
    Type: Application
    Filed: February 8, 2019
    Publication date: May 30, 2019
    Inventors: Jianjun Wang, Qianqian Li
  • Publication number: 20190101643
    Abstract: A device and a method for detecting main acoustic indexes of multi-beam sonar pertaining to the field of hydrographic surveying and charting technology. The device includes a rotating device and a lifting gear installed in an anechoic tank. The bottom of the rotating device is equipped with a multi-beam sonar that has its rotating plane perpendicular to the direction of track line and transmits signals along the horizontal direction. A standard hydrophone is equipped at the bottom of the lifting gear, and is connected with a signal collector. The device utilizes the standard hydrophone to receive the pulse signals transmitted by the multi-beam sonar and employs the multi-beam sonar to receive the standard sound source signals, designs the detection process for data collection for analysis and research, thereby achieving the detection of the frequency, source level and beam angle of multi-beam sonar.
    Type: Application
    Filed: January 16, 2018
    Publication date: April 4, 2019
    Applicant: SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Fanlin YANG, Xiankun WANG, Donghui LI, Qianqian LI, Bo SHI, Dong JING, Xiushan LU, Xiaodong CUI
  • Patent number: 10242612
    Abstract: A DLS array substrate and the display device thereof are disclosed. The DLS array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The first pixel and the second pixel share the same data line but connect to different scanning lines. The first pixels and the second pixels are arranged periodically along the row direction and the column direction, and the period along the row direction or the column direction includes three or four display pixels. The period along at least the row direction or at least the column direction includes three display pixels. With such configuration, the signals delay effect regarding the DLS may be alleviated, and the bright and dark lines issue may be overcome.
    Type: Grant
    Filed: December 25, 2015
    Date of Patent: March 26, 2019
    Assignee: Shenzhen China Star Optoelectronics Technology Co., Ltd
    Inventors: Qianqian Li, Je-hao Hsu, Chengcai Dong
  • Patent number: 10221397
    Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterial!y expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: March 5, 2019
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li
  • Publication number: 20190064674
    Abstract: Disclosed is a liquid chemical vapor recovery device, a wet stripping device, a photoresist stripping process and a method for manufacturing a thin film transistor-liquid crystal display using the same. The liquid chemical vapor recovery device comprises: an exhaust pipe for discharging a gas in a processing chamber for wet processing with a liquid chemical, the gas comprising a vapor of the liquid chemical; and a reflux pipe for refluxing the liquid chemical condensed in the exhaust pipe to a liquid chemical storage tank, the reflux pipe having an inlet connected to the exhaust pipe and an outlet connected to the liquid chemical storage tank, wherein, at least a part of the exhaust pipe positioned upstream of the inlet of the reflux pipe is formed as a pipe segment with a rugged inner surface.
    Type: Application
    Filed: April 13, 2018
    Publication date: February 28, 2019
    Inventors: Qianqian Li, Hao Yin, Yadong Xu, Mingming Wang, Xiaoning Liu, Yadong Liang, Dongseob Kim, Zhongren Jiang, Jun Geng, Shikai Wang
  • Publication number: 20190000982
    Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.
    Type: Application
    Filed: September 4, 2018
    Publication date: January 3, 2019
    Applicant: Qurgen, Inc.
    Inventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
  • Publication number: 20180342759
    Abstract: A lithium-ion battery cell and a lithium-ion battery including the lithium-ion battery cell are provided. The lithium-ion battery cell includes a positive plate, a membrane and a negative plate. Multiple positive lugs are arranged sequentially on the positive plate in a unfolded state, multiple negative lugs are arranged sequentially on the negative plate in a unfolded state. The positive plate and the negative plate are separated by the membrane and are wound to form the lithium-ion battery cell. The multiple positive lugs form a lug laminated structure or a lug staggered structure, and the multiple negative lugs form a lug laminated structure or a lug staggered structure.
    Type: Application
    Filed: October 25, 2016
    Publication date: November 29, 2018
    Inventors: Kuan Zhong, Shiyong Jiang, Wenhua Wang, Ying Li, Qianqian Li, Hongming Liu
  • Patent number: 10076574
    Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: September 18, 2018
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
  • Publication number: 20180127725
    Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterial!y expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.
    Type: Application
    Filed: November 9, 2017
    Publication date: May 10, 2018
    Inventors: Jianjun Wang, Qianqian Li
  • Patent number: 9965994
    Abstract: The array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The period along the row direction or the column direction includes three display pixels. Wherein within at least one period along the row direction and the column direction, the display pixel of the first row includes one second pixel and two first pixels adjacent to the second pixel. The display pixel of the second row includes one first pixel and two second pixels adjacent to the first pixel. The display pixel of the third row includes one first pixel and two second pixels adjacent to the first pixel, and the first pixel of the third row is in different column from the first pixel of the second row.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: May 8, 2018
    Assignee: Shenzhen China Star Optoelectronics Technology Co., Ltd
    Inventors: Qianqian Li, Je-hao Hsu, Zhenya Li
  • Publication number: 20180072911
    Abstract: The present invention provides an aqueous paint composition comprising by dry weight based on total dry weight of the pigment composition, from 11% to 35% of a polymeric duller of (co)polymeric particles having an average diameter of from 1 to 20 ?m, and from 25% to 70% of titanium dioxide particles; wherein from 50% to 100% of the titanium dioxide particles are encapsulated by polymer shell of (co)polymeric particles.
    Type: Application
    Filed: April 28, 2015
    Publication date: March 15, 2018
    Inventors: Junyu Chen, Wei Cui, Tao Wang, Tao Wang, Qianqian Li, Juan Li, Longlan Cui, David G. Speece, Jr.
  • Patent number: 9816076
    Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: November 14, 2017
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li
  • Publication number: 20170296615
    Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.
    Type: Application
    Filed: June 29, 2017
    Publication date: October 19, 2017
    Inventors: Jianjun Wang, Qianqian Li
  • Publication number: 20170236467
    Abstract: A DLS array substrate and the display device thereof are disclosed. The DLS array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The first pixel and the second pixel share the same data line but connect to different scanning lines. The first pixels and the second pixels are arranged periodically along the row direction and the column direction, and the period along the row direction or the column direction includes three or four display pixels. The period along at least the row direction or at least the column direction includes three display pixels. With such configuration, the signals delay effect regarding the DLS may be alleviated, and the bright and dark lines issue may be overcome.
    Type: Application
    Filed: December 25, 2015
    Publication date: August 17, 2017
    Applicant: Shenzhen China Star Optelectronics Technology
    Inventors: Qianqian LI, Je-hao HSU, Chengcai DONG
  • Publication number: 20170229054
    Abstract: The array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The period along the row direction or the column direction includes three display pixels. Wherein within at least one period along the row direction and the column direction, the display pixel of the first row includes one second pixel and two first pixels adjacent to the second pixel. The display pixel of the second row includes one first pixel and two second pixels adjacent to the first pixel. The display pixel of the third row includes one first pixel and two second pixels adjacent to the first pixel, and the first pixel of the third row is in different column from the first pixel of the second row.
    Type: Application
    Filed: December 28, 2015
    Publication date: August 10, 2017
    Applicant: Shenzhen China Star Optoelectronics Technology Co. Ltd.
    Inventors: Qianqian LI, Je-hao HSU, Zhenya LI