Patents by Inventor Qianqian Li
Qianqian Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20200132041Abstract: The present invention discloses a ducted bidirectional tidal current power station system, mainly consisting of a bidirectional tidal current power generation device, a dam, an open sea, an inland sea, a duct, and an opening/closing gate. The bidirectional tidal current power generation device is installed in the duct on the bottom of the dam. Openings, respectively communicated with the open sea and the inland sea, are formed at two ends of the duct, and an opening/closing gate is arranged at each of the two openings. By the ducted bidirectional tidal current power station system of the present invention, the cost of marine construction, operation and maintenance of the tidal current power generation device in an open sea area is saved, and the complex structure of the power generation device in the tidal power station and the cost of strict construction of auxiliary devices and runners are avoided.Type: ApplicationFiled: August 30, 2019Publication date: April 30, 2020Inventors: Liwei CHEN, Changlu LIU, Jianfeng YU, Dongli ZHANG, Yinhua CHEN, Qianqian LI, Yujuan WANG, Jinbo HU
-
Patent number: 10634784Abstract: A device and a method for detecting main acoustic indexes of multi-beam sonar pertaining to the field of hydrographic surveying and charting technology. The device includes a rotating device and a lifting gear installed in an anechoic tank. The bottom of the rotating device is equipped with a multi-beam sonar that has its rotating plane perpendicular to the direction of track line and transmits signals along the horizontal direction. A standard hydrophone is equipped at the bottom of the lifting gear, and is connected with a signal collector. The device utilizes the standard hydrophone to receive the pulse signals transmitted by the multi-beam sonar and employs the multi-beam sonar to receive the standard sound source signals, designs the detection process for data collection for analysis and research, thereby achieving the detection of the frequency, source level and beam angle of multi-beam sonar.Type: GrantFiled: January 16, 2018Date of Patent: April 28, 2020Assignee: SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Fanlin Yang, Xiankun Wang, Donghui Li, Qianqian Li, Bo Shi, Dong Jing, Xiushan Lu, Xiaodong Cui
-
Patent number: 10548983Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.Type: GrantFiled: September 4, 2018Date of Patent: February 4, 2020Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
-
Publication number: 20190336562Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.Type: ApplicationFiled: July 22, 2019Publication date: November 7, 2019Inventors: Jianjun Wang, Qianqian Li
-
Patent number: 10357532Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.Type: GrantFiled: June 29, 2017Date of Patent: July 23, 2019Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li
-
Publication number: 20190161739Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.Type: ApplicationFiled: February 8, 2019Publication date: May 30, 2019Inventors: Jianjun Wang, Qianqian Li
-
Publication number: 20190101643Abstract: A device and a method for detecting main acoustic indexes of multi-beam sonar pertaining to the field of hydrographic surveying and charting technology. The device includes a rotating device and a lifting gear installed in an anechoic tank. The bottom of the rotating device is equipped with a multi-beam sonar that has its rotating plane perpendicular to the direction of track line and transmits signals along the horizontal direction. A standard hydrophone is equipped at the bottom of the lifting gear, and is connected with a signal collector. The device utilizes the standard hydrophone to receive the pulse signals transmitted by the multi-beam sonar and employs the multi-beam sonar to receive the standard sound source signals, designs the detection process for data collection for analysis and research, thereby achieving the detection of the frequency, source level and beam angle of multi-beam sonar.Type: ApplicationFiled: January 16, 2018Publication date: April 4, 2019Applicant: SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Fanlin YANG, Xiankun WANG, Donghui LI, Qianqian LI, Bo SHI, Dong JING, Xiushan LU, Xiaodong CUI
-
Patent number: 10242612Abstract: A DLS array substrate and the display device thereof are disclosed. The DLS array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The first pixel and the second pixel share the same data line but connect to different scanning lines. The first pixels and the second pixels are arranged periodically along the row direction and the column direction, and the period along the row direction or the column direction includes three or four display pixels. The period along at least the row direction or at least the column direction includes three display pixels. With such configuration, the signals delay effect regarding the DLS may be alleviated, and the bright and dark lines issue may be overcome.Type: GrantFiled: December 25, 2015Date of Patent: March 26, 2019Assignee: Shenzhen China Star Optoelectronics Technology Co., LtdInventors: Qianqian Li, Je-hao Hsu, Chengcai Dong
-
Patent number: 10221397Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterial!y expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.Type: GrantFiled: November 9, 2017Date of Patent: March 5, 2019Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li
-
Publication number: 20190064674Abstract: Disclosed is a liquid chemical vapor recovery device, a wet stripping device, a photoresist stripping process and a method for manufacturing a thin film transistor-liquid crystal display using the same. The liquid chemical vapor recovery device comprises: an exhaust pipe for discharging a gas in a processing chamber for wet processing with a liquid chemical, the gas comprising a vapor of the liquid chemical; and a reflux pipe for refluxing the liquid chemical condensed in the exhaust pipe to a liquid chemical storage tank, the reflux pipe having an inlet connected to the exhaust pipe and an outlet connected to the liquid chemical storage tank, wherein, at least a part of the exhaust pipe positioned upstream of the inlet of the reflux pipe is formed as a pipe segment with a rugged inner surface.Type: ApplicationFiled: April 13, 2018Publication date: February 28, 2019Inventors: Qianqian Li, Hao Yin, Yadong Xu, Mingming Wang, Xiaoning Liu, Yadong Liang, Dongseob Kim, Zhongren Jiang, Jun Geng, Shikai Wang
-
Publication number: 20190000982Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.Type: ApplicationFiled: September 4, 2018Publication date: January 3, 2019Applicant: Qurgen, Inc.Inventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
-
Publication number: 20180342759Abstract: A lithium-ion battery cell and a lithium-ion battery including the lithium-ion battery cell are provided. The lithium-ion battery cell includes a positive plate, a membrane and a negative plate. Multiple positive lugs are arranged sequentially on the positive plate in a unfolded state, multiple negative lugs are arranged sequentially on the negative plate in a unfolded state. The positive plate and the negative plate are separated by the membrane and are wound to form the lithium-ion battery cell. The multiple positive lugs form a lug laminated structure or a lug staggered structure, and the multiple negative lugs form a lug laminated structure or a lug staggered structure.Type: ApplicationFiled: October 25, 2016Publication date: November 29, 2018Inventors: Kuan Zhong, Shiyong Jiang, Wenhua Wang, Ying Li, Qianqian Li, Hongming Liu
-
Patent number: 10076574Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.Type: GrantFiled: October 27, 2014Date of Patent: September 18, 2018Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
-
Publication number: 20180127725Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterial!y expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.Type: ApplicationFiled: November 9, 2017Publication date: May 10, 2018Inventors: Jianjun Wang, Qianqian Li
-
Patent number: 9965994Abstract: The array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The period along the row direction or the column direction includes three display pixels. Wherein within at least one period along the row direction and the column direction, the display pixel of the first row includes one second pixel and two first pixels adjacent to the second pixel. The display pixel of the second row includes one first pixel and two second pixels adjacent to the first pixel. The display pixel of the third row includes one first pixel and two second pixels adjacent to the first pixel, and the first pixel of the third row is in different column from the first pixel of the second row.Type: GrantFiled: December 28, 2015Date of Patent: May 8, 2018Assignee: Shenzhen China Star Optoelectronics Technology Co., LtdInventors: Qianqian Li, Je-hao Hsu, Zhenya Li
-
Publication number: 20180072911Abstract: The present invention provides an aqueous paint composition comprising by dry weight based on total dry weight of the pigment composition, from 11% to 35% of a polymeric duller of (co)polymeric particles having an average diameter of from 1 to 20 ?m, and from 25% to 70% of titanium dioxide particles; wherein from 50% to 100% of the titanium dioxide particles are encapsulated by polymer shell of (co)polymeric particles.Type: ApplicationFiled: April 28, 2015Publication date: March 15, 2018Inventors: Junyu Chen, Wei Cui, Tao Wang, Tao Wang, Qianqian Li, Juan Li, Longlan Cui, David G. Speece, Jr.
-
Patent number: 9816076Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.Type: GrantFiled: May 2, 2012Date of Patent: November 14, 2017Assignee: Wayne State UniversityInventors: Jianjun Wang, Qianqian Li
-
Publication number: 20170296615Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.Type: ApplicationFiled: June 29, 2017Publication date: October 19, 2017Inventors: Jianjun Wang, Qianqian Li
-
Publication number: 20170236467Abstract: A DLS array substrate and the display device thereof are disclosed. The DLS array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The first pixel and the second pixel share the same data line but connect to different scanning lines. The first pixels and the second pixels are arranged periodically along the row direction and the column direction, and the period along the row direction or the column direction includes three or four display pixels. The period along at least the row direction or at least the column direction includes three display pixels. With such configuration, the signals delay effect regarding the DLS may be alleviated, and the bright and dark lines issue may be overcome.Type: ApplicationFiled: December 25, 2015Publication date: August 17, 2017Applicant: Shenzhen China Star Optelectronics TechnologyInventors: Qianqian LI, Je-hao HSU, Chengcai DONG
-
Publication number: 20170229054Abstract: The array substrate includes a substrate and at least one display pixel arranged on the substrate. The display pixel includes a plurality of first pixels and a plurality of second pixels arranged along a row direction and a column direction. The period along the row direction or the column direction includes three display pixels. Wherein within at least one period along the row direction and the column direction, the display pixel of the first row includes one second pixel and two first pixels adjacent to the second pixel. The display pixel of the second row includes one first pixel and two second pixels adjacent to the first pixel. The display pixel of the third row includes one first pixel and two second pixels adjacent to the first pixel, and the first pixel of the third row is in different column from the first pixel of the second row.Type: ApplicationFiled: December 28, 2015Publication date: August 10, 2017Applicant: Shenzhen China Star Optoelectronics Technology Co. Ltd.Inventors: Qianqian LI, Je-hao HSU, Zhenya LI