Abstract: Disclosed herein is a newly identified secreted nanoparticle that is morphologically and molecularly distinct from the recently described nanoparticle termed an exomere. The disclosed nanoparticle is referred to herein as a supermere. Both exomeres and supermeres are amembranous in contrast to membrane-enclosed extracellular vesicles (EVs). Supermeres are smaller and morphologically distinct from exomeres. These supermeres contain cargo with diagnostic and therapeutic applications.

Abstract: A glycosylation method involving a trivalent iodine reagent, wherein a glycosyl donor (I) is activated in the presence of a trivalent iodine reagent and a transition metal catalyst, and then reacts with a acceptor (II) under acid catalysis or directly to obtain a glycosylation product (III); in the glycosyl donor (I), Gly is a glycosyl group in which one or more hydroxyl groups on the sugar ring are protected by a protecting group; X is an oxygen, sulfur, or selenium atom; R is an alkyl group or an aryl group; the acceptor (II) is a nucleophile selected from sugars, alcohols, phenols, flavonoids, carboxylic acids, phosphates, pyrimidines, purines, amides, sulfonamides, guanidines, arylamines, indoles, enol silyl ethers, thiols, or thiophenol containing one or more free hydroxyl groups.

Abstract: Provided is a thin-film transistor. The thin-film transistor includes: a gate, a first insulative layer, a semiconductor layer, a source and drain layer, a semiconductor modification layer, and a second insulative layer that are disposed on a base substrate and sequentially laminated in a direction away from the base substrate; wherein the source and drain layer includes a source and a drain that are spaced apart and both connected to the semiconductor layer, a portion of the semiconductor layer is exposed from a gap between the source and the drain, and the semiconductor modification layer at least covers the portion of the semiconductor layer exposed from the gap; and a concentration of hydrogen in the semiconductor layer is greater than a concentration threshold, and a temperature of a reaction chamber in manufacturing the thin-film transistor is less than a temperature threshold.

Abstract: Provided are a negative active material, a negative electrode plate, and a battery. The negative active material includes graphite. A specific surface area of the negative active material before a compaction process on the negative active material is X1. A specific surface area of the negative active material after the compaction process is X2. An orientation index of the negative active material before the compaction process is OIa. The negative active material satisfies 0.05<(X2?X1)/OIa<0.5, where X1 and X2 are in units of m2/g.

Abstract: A control method for stabilizing excimer laser pulse energy includes: obtaining a measured energy value of the n-th pulse in a pulse sequence; calculating the difference between the measured energy value and the preset energy value; taking the z-th pulse of the sequence as a demarcation point, when n is a positive integer less than z, the discharge voltage value of the next pulse is calculated according to a first mathematical model, and when n is an integer greater than z?1, the discharge voltage value of the next pulse is calculated according to a second mathematical model; and the next pulse is generated according to the discharge voltage value. A control system based on the control method includes: a high-voltage discharge module, a laser cavity, a laser parameter measurement module, and an energy stability controller.

Abstract: A glycosylation method involving a trivalent iodine reagent, wherein a glycosyl donor (I) is activated in the presence of a trivalent iodine reagent and a transition metal catalyst, and then reacts with a acceptor (II) under acid catalysis or directly to obtain a glycosylation product (III); in the glycosyl donor (I), Gly is a glycosyl group in which one or more hydroxyl groups on the sugar ring are protected by a protecting group; X is an oxygen, sulfur, or selenium atom; R is an alkyl group or an aryl group; the acceptor (II) is a nucleophile selected from sugars, alcohols, phenols, flavonoids, carboxylic acids, phosphates, pyrimidines, purines, amides, sulfonamides, guanidines, arylamines, indoles, enol silyl ethers, thiols, or thiophenol containing one or more free hydroxyl groups.

Abstract: A negative active material includes a porous structure having micropores, mesopores, and macropores, where a pore volume of the negative active material satisfies: 0.5%?V1/V2?2% and 30%?V2/(V2+V3)?50%, where V1 represents a pore volume of the micropores in the negative active material, V2 represents a pore volume of the mesopores in the negative active material, and V3 represents a pore volume of the macropores in the negative active material.

Abstract: Provided herein are diastereomer-selective synthetic methods and intermediates for making chiral 3,5-disubstituted morpholine compounds, which are useful for the preparation of compounds useful as mitochondrial-derived activator of caspases (SMAC) mimetics for the treatment of proliferative diseases such as cancer.

Abstract: The present disclosure relates to the technical field of medical equipment, and discloses an articulating endoscopic cutter stapler and universal assembly for stapling, comprising a proper, wherein the surface of the proper is slidably connected with a reset ring and formed with a slot, the surface of the reset ring is provided with a sliding pin which is placed into the slot, and a safety pin is arranged at one end of the surface of the proper. The present disclosure can better control the anvil assembly to improve the stability of stapler during suturing of wound and to improve the quality of surgical suturing. The angle of suturing assembly of stapler can also be adjusted to the specific position of the wound, so that the range of application of stapler can be extended.

Abstract: This invention relates to the field of genetic molecular breeding, specifically to a pig 50K liquid-phase chip based on multiple single nucleotide-polymorphism and its application. The probe design of the chip in this invention takes into account the distribution of captured SNP loci across the genome, the polymorphism of the loci, the quality of mSNP markers, and other issues, effectively avoiding problems such as uneven marker density and poor polymorphism. It also considers the quality of mSNP markers and the issue of linkage disequilibrium among mSNP markers. While adhering to the basic principles of liquid-phase chip design, genomic regions with moderate linkage disequilibrium between markers were selected, generating more SNP markers with high genotyping quality and moderate linkage disequilibrium within the probe region with the target loci. The mSNP liquid-phase chip of this invention expands the detectable number of SNPs to 1.

Abstract: An information handling system executes test cases against a code that includes a set of functions, wherein the execution is performed at least twice using a different trace switch value. The system also identifies trace logs associated with each test case, and maps each test case to one or more functions based on the association of the trace logs with each test case.

Abstract: A negative electrode sheet, a battery, and an electricity-consumption device are disclosed. The negative electrode sheet includes a current collector and a negative active material layer. When a state of charge of a battery is 100% or a voltage of the battery is 3.65 V, a differential scanning calorimeter curve of the negative active material layer includes: a first exothermic peak from 120° C. to 150° C., in which the negative active material layer has heat release A1 satisfying 2J/gSA1?50 J/g; a second exothermic peak from 220° C. to 260° C., in which the negative active material layer has heat release A2 satisfying 20J/g?A2?100 J/g; and a third exothermic peak from 260° C. to 310° C., in which the negative active material layer has heat release A3 satisfying 200J/g?A3?600J/g.

Abstract: A negative electrode sheet, a secondary battery, and an electricity-consumption device are provided. The negative electrode sheet includes a negative active material layer. Heat release Q of the negative active material layer immersed in electrolyte satisfies 220 J/g?Q?600 J/g.

Abstract: A negative electrode sheet and a screening method thereof, a battery and an electric equipment are provided. The negative electrode sheet comprises a current collector and a negative active material layer arranged on the current collector. The negative active material layer has negative active particles, and each negative active particle satisfy the relation: 0.7?R50/Dv50?0.95; R50 is an equivalent average spherical diameter of the negative active particles, and Dv50 is a corresponding particle diameter when a cumulative volume fraction in a volume-based distribution reaches 50% in the particle diameter distribution measurement by a laser scattering method.

Abstract: Provided are a negative active material, a negative electrode plate, a battery, a battery module, and an electric device. A particle size distribution A of the negative active material is (D90?D10)/D50. a defect degree B of the negative active material is ID/IG. A ratio of the particle size distribution A of the negative active material to the defect degree B of the negative active material is 6.0?A/B?7.2.

Abstract: The subject matter described herein provides systems and techniques to automatically configure a proximal device, such as a smart watch, a tablet, or any other smart device, based on configuration information sent from the user equipment (UE) to the proximal device when the local communications connection, such as a wireless connection, between the devices is weak. If it is determined that there is a weak local communications connection between the UE and the proximal device the UE may automatically send network configuration information to the proximal device. If it is determined that there is a weak local communications connection between the UE and the proximal device the UE may automatically turn on its mobile hotspot, and automatically send the mobile hotspot configuration information to the proximal device.

Abstract: A component of a cellular user equipment (UE) device is configured to detect adverse radio link conditions. The component monitors a plurality of layers of a communication stack of the UE device during an active voice call. Responsive to monitoring the plurality of layers, the component detects at least one adverse radio link condition associated with the active voice call. The component provides a radio link degradation indication to a second component of the UE device in response to detecting the at least one adverse radio link condition.

Abstract: A novel detection scheme and all fiber optic temperature sensor is disclosed. The apparatus comprising a sensing loop; a laser diode driver; a coupler; a first photodetector coupled to the coupler output to produce a current; an amplifier to convert and amplify the current to voltage; an A/D converter to convert the voltage to digital signal; an AOEO regenerator to convert coupler optical output to electronic signal while preserving timing information and electronic signal to regenerated optical signal; a timer to control AOEO delay time; optical fiber probe; and microcontroller coupled to laser diode driver, A/D converter, and timer; and configured to control first optical signal timing and AOEO delay time; and configured to process digital signal based on its time of flight variation to determine a temperature change, and wherein sensitivity increases with increasing optical fiber length and/or number of regenerated optical signals. Other embodiments are described and claimed.

Abstract: Methods and systems for rotating elements displayed by computing devices are described herein. At least one image of a user of a computing device may be captured by a camera of the computing device. An angle of the eyes of the user with respect to the computing device may be determined. Based on that determined angle, at least one element of content displayed by the computing device may be rotated so as to allow for display of that element in an orientation consumable by the user. For example, the element might be rotated at an angle corresponding to the angle of the eyes of the user with respect to the orientation of the computing device.

Abstract: Systems and methods to confirm safe delivery of treatment energy to a patient by identifying a presence of a fault in an energy delivery pathway and identifying a location of the fault within the device. The system includes a processing unit configured to calculate blood impedances external to the device based on known impedance characteristics of the device, and then to calculate impedances within the device during energy delivery based on the calculated blood impedances. The processing unit prevents the delivery of energy in an energy delivery pathway that is determined to be compromised. The processing unit is also configured to compare times for two different frequencies to travel a predetermined distance, the difference in the times corresponding to a location of a fault within the energy delivery pathway.