Abstract: The present teaching relates to method, system, medium, and implementations for fusing a 3D virtual model with a 2D image associated with an organ of a patient. A key-pose is determined as an approximate position and orientation of a medical instrument with respect to the patient's organ. Based on the key-pose, an overlay is generated on a 2D image of the patient's organ, acquired by the medical instrument, by projecting the 3D virtual model on to the 2D image. A pair of feature points includes a 2D feature point from the 2D image and a corresponding 3D feature point from the 3D virtual model. The 3D coordinate of the 3D feature point is determined based on the 2D coordinate of the 2D feature point. The depth of the 3D coordinate is on a line of sight of the 2D feature point and is determined so that the projection of the 3D virtual model from the depth creates an overlay approximately matching the organ observed in the 2D image.

Abstract: Analytics information is generated in a new generation mobile network. A first network entity generates the analytics information, and a second network entity and a third network entity support the analytics generation. The first network entity is configured to obtain, from the second network entity or from one or more third network entities, past and/or current association information for an area of interest. Further, it is configured to provide analytics information based on the obtained association information for the area of interest. The past and/or current association information indicates one or more other network entities and/or network properties that, respectively, have been and/or are mapped to or serving the area of interest.

Abstract: A network entity determines at least one model parameter of a model for digitally analyzing input data depending on the at least one model parameter of a model, the network entity being configured to receive a model request from a requesting entity over the communication network, the model request requesting the at least one model parameter of the model, to obtain the requested at least one model parameter by at least one of the following: executing a machine-learning model training algorithm, the machine-learning model training algorithm being configured to train the model with input data in order to determine at least one of the requested model parameter; searching a local data base for an existing model; or requesting the at least one model parameter from a further network entity; and to send the requested model parameter towards the requesting entity over the communication network.

Abstract: A local entity is proposed for determination of user equipment location in a mobile communication network. The local entity is configured to be run on a first user equipment and/or in an access network. The local entity is configured to receive location information of a target user equipment, and determine a location of the target user equipment based on the location information. This is advantageous because the determination of the location can be improved with regard to a determination of the location carried out by the core network. Particularly, the location can be determined without the core network being involved.

Abstract: Analytics information can be used in a mobile network. Network entities and corresponding methods support the generation of such analytics information. In particular, network entities and methods can facilitate the gathering of information required for the analytics generation. A network entity for analytics generation may be configured to obtain network slice association (NSA) information and/or user plane association (UPA) information from one or more other network entities, where the NSA information indicates a relation between an Access Network (AN) property and a Core Network (CN) property, and the UPA information indicates a network entity configured to transmit data traffic to and/or from a user equipment in the network. Further, the network entity may be configured to provide analytics information, the analytics information being based on the obtained NSA information and/or UPA information.

Abstract: The present disclosure relates to methods and apparatus for determining device information. In one example method, an inference device sends a first request to a service discovery entity. The first request is used to request information about one or more training devices, and the first request includes an algorithm type or an algorithm identifier of a first model requested by the inference device. The inference device receives the information about the one or more training devices from the service discovery entity. The information about the one or more training devices includes capability information. The inference device determines a first training device from the information about the one or more training devices based on a preset condition.

Abstract: The present teaching relates to surgical procedure planning. In one example, at least one 3D object contained in a 3D volume is rendered on a display screen. The at least one 3D object includes a 3D object corresponding to an organ. First information related to a 3D pose of a surgical instrument positioned with respect to the at least one 3D object is received from a user. A 3D representation of the surgical instrument is rendered in the 3D volume based on the first information. Second information related to a setting of the surgical instrument is received from the user. A 3D treatment zone in the 3D volume with respect to the at least one 3D object is estimated based on the first and second information. The 3D treatment zone in the 3D volume is visualized on the display screen. Controls associated with the 3D representation of the surgical instrument and/or the 3D treatment zone are provided to facilitate the user to dynamically adjust the 3D treatment zone via the controls.

Abstract: A method, implemented on a machine having at least one processor, storage, and a communication platform capable of connecting to a network for characterizing a tumor embedded inside a medium, comprising: measuring at least one of a mechanical property and a spectral property of the tumor.

Abstract: The present disclosure discloses a method for inhibiting formation of a biofilm of bacteria. Specifically, the method may include treating the bacteria with an effective amount of a coumarin-chalcone compound. While inhibiting the formation of the biofilm of the bacteria, the effective amount of the coumarin-chalcone compound may reduce virulences of the bacteria and enhance a susceptibility of the bacteria to an antibiotic when applied in combination with the antibiotic. The present disclosure further discloses a composition including an effective amount of the coumarin-chalcone compound. The composition may be used to inhibit the formation of the biofilm of bacteria. The composition may also include an antibiotic, a minimal inhibitory concentration and a minimal biofilm eliminate concentration of which are reduced when the composition is used.

Abstract: The present disclosure relates to handover (HO) of a user equipment (UE), which consumes a quality of service (QoS) flow that is associated with multiple QoS profiles. The disclosure proposes a network entity for supporting HO of the UE, and proposes a second network entity that is the target of HO of the UE. The network entity is configured to: obtain multiple QoS profiles associated with a QoS flow; obtain QoS capability information indicating whether the second network entity supports more than one QoS profile and/or whether a first network entity supports more than one QoS profile; and provide at least one message to the second network entity, wherein the at least one message includes at least one QoS profile according to the QoS capability information.

Abstract: An entity, particularly a Radio Access Network (RAN) entity, adjusts Quality of Service (QoS) of at least one QoS flow in a RAN. The entity is configured to: obtain assistance information for an adjustment of at least one QoS profile for the at least one QoS flow of at least one wireless communication device, particularly of at least one user equipment (UE); and provide, to a second entity, particularly to a Core Network (CN) entity, a request for an adjustment or QoS information for the adjustment from a first QoS profile to a second QoS profile of a first QoS flow. The request or the QoS information is based on the assistance information.

Abstract: A network entity is proposed for controlling the use, by a user equipment, of network slices of a communication network comprising a plurality of slice support areas. Each slice support area comprises at least one cell, and all cells of a given slice support area support the same network slices. A registration area for the registration of the user equipment with the communication network comprises at least one slice support area. The network entity is adapted to transmit, to the user equipment, slice support information for at least one slice support area of the communication network. The slice support information for a given slice support area indicates at least one network slice supported by the given slice support area and/or at least one network slice not supported by the given slice support area.

Abstract: The present disclosure relates to robot path planning. Depth information of a plurality of obstacles in an environment of a robot are obtained at a first time instance. A static distance map is generated based on the depth information. A path is computed for the robot based on the static distance map. At a second time instant, depth information of one or more obstacles is obtained. A dynamic distance map is generated based on the one or more obstacles, wherein for each obstacle that satisfies a condition: a vibration range of the obstacle is computed based on a position of the obstacle and the static distance map, and the obstacle is classified as a dynamic obstacle or a static obstacle based on a criterion associated with the vibration range. A repulsive speed of the robot is computed based on the dynamic distance map to avoid the dynamic obstacles.

Abstract: A roller track includes a base, parallel guides, roller support bars placed into their respective guides, and a plurality of rollers removably disposed between the roller support bars. The roller support bars preferably are removably secured to the base via the respective guides which are affixed to the base. The base also can be provided with connecting elements sidewalls thereof such that a plurality of bases of roller tracks can be connected laterally to accommodate any width of shelf or display planogram. Thus, the roller tracks can be used either separately roller tracks or as a continuous mat (i.e. a plurality of roller tracks affixed to adjacent roller tracks). Additionally, dividers can be removably affixed to each roller track via securing members comprising an upper body portion formed via a living hinge and at least one lower connector that removably connects the securing member to the roller track.

Abstract: Disclosed in the present invention is a multi-target chimeric antigen receptor. Provided in the present invention is a multi-target chimeric antigen receptor consisting of a main peptide chain and an auxiliary peptide chain; the main peptide chain comprises an antigen binding domain A, an auxiliary peptide chain connecting domain B, a transmembrane domain C and an intracellular signaling domain D; the auxiliary peptide chain comprises a main peptide chain connecting domain F; the antigen binding domain A is a polypeptide having an antigen-binding function; the auxiliary chain connecting domain B and the main peptide connecting domain F are combined with each other; the transmembrane domain C is a transmembrane domain of any membrane-binding protein or a transmembrane protein; and the intracellular signaling domain D comprises a primary signaling region.

Abstract: A multifunctional polypeptide chain or a protein. A polypeptide chain X, comprising an antigen 1 binding domain R1, an auxiliary peptide chain linking domain R2 and an antigen 2 binding domain R3. The auxiliary peptide chain linking domain R2 is a cytokine or a cytokine binding domain in a cytokine receptor. A protein, which is a heterodimer composed of the polypeptide chain X as a main peptide chain and an auxiliary peptide chain Y. The auxiliary peptide chain Y comprises an antigen 3 binding domain R4 and a main peptide chain X linking domain R5, or the auxiliary peptide chain Y is the main peptide chain linking domain R5. The multifunctional protein mediates specific cell killing by binding to different tumor antigens with the two antigen binding domains of tumor-associated antigens therein. The multifunctional protein can function as a cytokine by introducing a cytokine or a cytokine receptor complex.

Abstract: The present teaching relates to surgical procedure planning. In one example, at least one 3D object contained in a 3D volume is rendered on a display screen. The at least one 3D object includes a 3D object corresponding to an organ. First information related to a 3D pose of a surgical instrument positioned with respect to the at least one 3D object is received from a user. A 3D representation of the surgical instrument is rendered in the 3D volume based on the first information. Second information related to a setting of the surgical instrument is received from the user. A 3D treatment zone in the 3D volume with respect to the at least one 3D object is estimated based on the first and second information. The 3D treatment zone in the 3D volume is visualized on the display screen. Controls associated with the 3D representation of the surgical instrument and/or the 3D treatment zone are provided to facilitate the user to dynamically adjust the 3D treatment zone via the controls.

Abstract: A roller track includes a base, parallel guides, roller support bars placed into their respective guides, and a plurality of rollers removably disposed between the roller support bars. The roller support bars preferably are removably secured to the base via the respective guides which are affixed to the base. The base also can be provided with connecting elements sidewalls thereof such that a plurality of bases of roller tracks can be connected laterally to accommodate any width of shelf or display planogram. Thus, the roller tracks can be used either separately roller tracks or as a continuous mat (i.e. a plurality of roller tracks affixed to adjacent roller tracks). Additionally, dividers can be removably affixed to each roller track via securing members comprising an upper body portion formed via a living hinge and at least one lower connector that removably connects the securing member to the roller track.

Abstract: A method supports transfer of service traffic between an external network entity and a second network entity. The method includes: sending, by the second network entity, a first transfer request to a first network entity, wherein the transfer request includes first service traffic; receiving, by the first network entity, the first transfer request from the second network entity, and sending, by the first network entity, a second transfer request to the external network entity, the second transfer request including the first service traffic; and receiving, by the second network entity, a fourth transfer request from the first network entity, the fourth transfer request including second service traffic.

Abstract: Embodiments of the present invention provide systems and methods for visualizing and querying data. Data subsets within an original table are examined. Values within the data subsets are extracted. Based on the extracted values, a new table is generated. The data contents of the original table differ from the data contents of the new table. Thus, the resulting visualization of the original table differs from the resulting visualization of the new table.