Abstract: A camera module includes a base frame, a photosensitive chip, a first substrate, a first driving mechanism, a first guide post, a second substrate, a second guide post, and a second driving mechanism. The first guide post is disposed on the base frame, the first substrate is movably connected to the first guide post and is capable of moving along an extension direction of the first guide post; the photosensitive chip is disposed on the second substrate, the second guide post is disposed on the first substrate, the second substrate is movably connected to the first guide post, and the second substrate moves along an extension direction of the second guide post; the first driving mechanism includes a first driving motor, and the first driving motor is disposed on the base frame and is connected to the first substrate; and the second driving mechanism includes a second driving motor.

Abstract: One example method includes obtaining a group of two dimensional images of a target, rendering, in real time immediately after the two dimensional images are obtained, a three dimensional model of the target, using the two dimensional images, and generating an output comprising the three dimensional model. The three dimensional model may then be compared with another version of the three dimensional model to identify a change in a condition of a structural element that is included in both of the three dimensional models.

Abstract: The present disclosure relates to a sgRNA and constructing a dual pig model of severe immunodeficiency and liver injury and use thereof. The method comprises the steps of knocking out RAG2, IL2R? and FAH genes in a porcine fetal fibroblast by using a CRISPR/Cas9 technology, constructing a RAG2?/?/IL2R??/Y/FAH?/? triple-gene edited cloned pig by using a somatic cell nuclear transfer technology, and obtaining a dual pig model of severe immunodeficiency and liver injury through phenotypic analysis and identification. The method overcomes the problems of long production period, low efficiency, irreversible damage, unsatisfactory use in a humanization degree and the like in the existing model construction technology, can realize a batch construction of the dual pig model of severe immunodeficiency and liver injury by a continuous cloning technology, and has great advantages and potential market application prospects in the related fields of tumor biology, cell transplantation, humanized animal models and the like.

Abstract: Provided is a portable display device, which comprises a clamping mechanism and a display body. The clamping mechanism comprises a bracket, a left mounting member, a left connecting member, a right mounting member, and a right connecting member. The left end and the right end of the bracket are respectively provided with a mounting cavity. The left connecting member and the right connecting member are respectively provided with a left L-shaped clamping element and a right L-shaped clamping element, which are symmetrically arranged. The portable display device of the disclosure can accommodate the varied usage habits of different users.

Abstract: Provided are a determination method and apparatus of a main shaft bearing state, an electronic device, and a storage medium. The method includes the following steps: Bearing swing data of a target main shaft bearing at multiple moments within a preset time period are acquired; at least one current data period and current-period bearing swing data in each current data period are determined according to the multiple pieces of bearing swing data; a first abrupt change value and a second abrupt change value are determined according to the current-period bearing swing data in each current data period; and a main shaft bearing state of the target main shaft bearing is determined according to the first abrupt change value and the second abrupt change value.

Abstract: The present disclosure provides systems and methods for motion correction of a positron emission computed tomography (PET) image. The method may include: obtaining scanned images of a scanned object generated at a plurality of time points; and determining a parametric image by performing a correction processing on the scanned images, wherein the correction processing may be configured to correct an influence of a motion of the scanned object on the scanned images.

Abstract: Provided are a system and a method for positron emission computed tomography (PET) image reconstruction. The method may be implemented on a computing device having at least one processor and at least one storage device, comprising: determining correction data based on original PET data (210); determining reconstruction data to be reconstructed based on the correction data (220); and generating, based on the reconstruction data, one or more of a PET reconstruction image and a PET parametric image (230).

Abstract: An integrated pressure condensing boiler is provided which relates to the technical field of boilers. The integrated pressure condensing boiler includes a pressure-bearing housing, a heat-exchange furnace arranged in the pressure-bearing housing, a combustion chamber communicating with the heat-exchange furnace and cooling tube groups fixed in the heat-exchange furnace. Heat-exchange medium flows from bottom to top in the pressure-bearing housing and in the cooling tube groups, and exchanges heat with high-temperature flue gas flowing from top to bottom in the heat-exchange furnace, thus achieving a counterflow heat exchanging. The heat-exchange furnace includes a multi-stage heat-exchange chamber with each heat-exchange chamber being cylindrical. The heat-exchange chambers are arranged in sequence from top to bottom to achieve a flue gas diffusing manner that high-temperature flue gas diffuses from center part to periphery and then gathers from periphery to center part.

Abstract: Provide a method, system, and medium for processing an image. The method comprises: obtaining a plurality of dynamic frame images, each of the plurality of dynamic frame images at least including dynamic image information of a target region; and determining the time-activity curve by processing the plurality of dynamic frame images.

Abstract: A target used for heavy water reactor production of C-14 isotopes, which comprises: a target tube, which has a target material and/or an absorber material, the target material being a nitrogen-containing solid material; end plates, which are arranged at two ends of the target tube; a connection rod, which is provided with a connection component that is connected to a positioning mechanism used for positioning the target, wherein the connection rod passes through the target tube along the axial direction of the target tube, and the target tube is fixedly connected to the connection rod by means of the end plates. The present invention can be adapted to be placed at different locations such as at a guide tube, an inspection passage, or a fuel channel to undergo irradiation and produce C-14 isotopes.

Abstract: A multi-dimensional spatial positioning system and method for disturbance source. The system includes a distributed-optical fiber sensor, a sensing optical fiber, a coordinate system, a disturbance source to be monitored, a first signal group, and a second signal group. The disturbance source is positioned by combining an array signal processing method with the distributed optical fiber sensor, using different laying manners for the sensing optical fiber and a certain number of flexibly selected sensing units distributed a certain distance from each other along a line, and combining with a special signal processing method, thereby realizing a function of being capable of monitoring multi-dimensional spatial position information of the disturbance source in real time in both short and long distances.

Abstract: A playback device including a housing, an audio player, a sound insulation cover, a target detection apparatus, and a driving mechanism. A sound hole is disposed on the housing, the sound insulation cover is disposed in the housing, the audio player is disposed in the sound insulation cover, a sound outlet is disposed on the sound insulation cover, the target detection apparatus is configured to detect a target direction, the driving mechanism is connected to the sound insulation cover, and in a case that the sound outlet does not face the target direction, the driving mechanism is controlled to start, and the driving mechanism drives the sound insulation cover to rotate, so that the sound outlet faces the target direction. This application discloses a control method for a playback device, a control apparatus for a playback device, and a computer-readable storage medium.

Abstract: The invention provides an N-benzyl-N-arylsulfonamide derivative, which is an N-benzyl-N-arylsulfonamide compound represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof. The N-benzyl-N-arylsulfonamide derivative is obtained by condensing a substituted nitrobenzene with 5- or 6-membered nitrogen-containing aliphatic heterocycle (the ring B), reducing the nitro group to an amino group, and subjecting the amino group to reductive amination, sulfonamidation; or by subjecting a substituted nitrobenzene to nitro reduction, reductive amination and sulfonamidation, and condensing the resultant intermediate with 5- or 6-membered nitrogen-containing aliphatic heterocycle (the ring B). It has been experimentally demonstrated that the N-benzyl-N-arylsulfonamide derivative of the invention can specifically bind to Kv1.3 potassium channel and inhibit or decrease its activity, and is useful in the treatment of autoimmune diseases caused by abnormal activation of the Kv1.

Abstract: Disclosed herein are gene therapy vectors used for efficiently transducing cells to express a human ?-globin gene. Specifically disclosed is an expression vector which comprises: an expression cassette for a ?-globin gene, which comprises exons and introns of human ?-globin gene, as well as cis-acting elements including one or more of WPRE, SV40 polyadenylation signal and/or SV40 ori. The disclosed expression vectors have significantly enhanced viral vector packaging efficiency in viral vector packaging cell lines, which leads to effective integration of lentiviral vectors and high expression level of ?-globin gene in target cells. Also disclosed are pharmaceutical compositions and therapeutic methods utilizing such expression vectors.

Abstract: The present disclosure relates to systems and methods for medical imaging. The systems may obtain an initial image of an object. The initial image may include a first region of interest (ROI) and one or more second ROIs. The systems may determine, based on the initial image, a first position corresponding to the first ROI and one or more second positions each of which corresponds to one of the one or more second ROIs. The systems may obtain scan data of the object by causing an imaging device to scan the object based on the first position and the one or more second positions. The systems may determine an injection parameter of a drug that is injected into the object based on the scan data. The systems may generate a target image of the object based on the injection parameter and the scan data of the object.

Abstract: A method and a system for positron emission tomography (PET) imaging may be provided. Scan data of an object in a first time period of a PET scan of the object may be obtained. A reference image of the object may be also obtained. The reference image may be reconstructed based on reference scan data in a second time period of the PET scan. A target image of the object in the first time period may be generated using an image reconstruction model based on the scan data in the first time period and the reference image of the object.

Abstract: The present invention discloses a Web-side real-time hybrid rendering method, device and computer equipment combined with ray tracing. The method includes acquiring three-dimensional scene data and the textures transformed according to the three-dimensional scene data; for the part with slow convergence speed and low frequency of rendering result, employ rasterization rendering according to the three-dimensional scene data; for the part with fast convergence speed and high-frequency rendering results, employ ray tracing rendering according to the texture; according to the rasterization rendering result and/or the ray tracing rendering result, the rendering results of the current frame and the historical frame are mixed. In this way, the problem of low rendering realism on the Web-side was solved, and high-quality global illumination effects can be achieved on the Web-side at a relatively low cost, which enhances the realism of rendering on the Web-side.

Abstract: Embodiments of the present disclosure provide a method for parameter imaging. The method includes: obtaining two scan images of an object, wherein scanning ranges of the two scan images have an overlapping region; obtaining frame information by framing the two scan images or two sets of scan data corresponding to the two scan images, wherein the overlapping region in the two scan images corresponds to two frames; and determining metabolic information of a tracer inside the object based on the frame information.

Abstract: A distributed fiber-optic acoustic sensing system and a signal processing method. The distributed fiber-optic acoustic sensing system is based on a high spatial resolution distributed fiber-optic acoustic sensor. The interval between adjacent sensing units is centimeter or millimeter level. Through specific digital signal processing, signal enhancement can be realized, noise in the system and environment are suppressed, at the same time, problems such as interference fading is solved, and the sensor signal-to-noise ratio of subunits can be increased by two to three orders of magnitude. Each subunit can serve as an independent high-sensitivity sensor for sensing. The multiple subunits can form one or more new sensor arrays. The azimuth estimation and spatial orientation of signal sources can be realized by the array signal processing method.

Abstract: The present disclosure relates to a construction method for a deformable anchor cable capable of being prestressed. The anchor cable includes an outer sleeve, a shrinkage pipe, an inner sleeve, a steel strand, an anchor and a tray. When the anchor cable is in use, a hole is drilled first, then the anchor cable is mounted in the drilled hole, and finally a prestress is applied to the steel strand of the anchor cable. According to the construction method, the construction is convenient; the anchor cable has the characteristics of high strength and large deformation, and can be easily prestressed; and the large deformation is realized by squeezing the inner sleeve by means of the anchor, which completely overcomes the problem of breaking a cold-drawn rod during the large deformation process.