Abstract: Methods and systems for detecting systemwide service issues by using anomaly localization. In an example, a method includes receiving time-series monitoring data for multiple services, the time-series monitoring data including multiple dimensions and an error metric; for the monitoring data from each service, evaluating scopes within the monitoring data based on an objective function for a time-series of the error metric to identify at least one anomalous scope, each scope including at least one dimension and a value for the dimension; based on evaluating the scopes, generating a ranked list of scopes for each service based on objective function scores for the scopes; correlating the ranked lists of scopes across the multiple services to identify a cross-service anomaly; and generating an alert for the services based on the cross-service anomaly, the alert indicating at least one scope as a potential root cause for the cross-service anomaly.

Abstract: A dynamic loose vehicle formation method based on real-time online navigation map, which belongs to the field of vehicle formation technologies. The method includes a driver inputs travel information of a destination and waypoints in a GIS app; the GIS app uploads the travel information to a GIS server; the driver chooses to join a recommended formation or create a formation in the GIS app; when the driver chooses the formation and joins the formation, the formation information is displayed on the GIS app interface and sent to other vehicles within the formation for information interaction; when the driver chooses to leave the formation and leaves the formation, the formation is adjusted and the GIS server updates the formation information.

Abstract: The present invention provides an antimicrobial coating composition comprising (i) a polymer emulsion and (ii) from 20 ppm to 6000 ppm, by dry weight based on total dry weight of the coating composition, a silver, and the polymer emulsion comprises, as polymerized units, (a) ethylenically unsaturated nonionic monomers, and (b) from 0.01% to 20%, by dry weight based on total dry weight of the polymer emulsion, heterocyclic group-containing monomers.

Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.

Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.

Abstract: Disclosed are a benzonitric heterocyclic compound, a preparation method therefor and the use thereof. Provided in the present invention is a benzonitric heterocyclic compound represented by formula I, or a pharmaceutically acceptable salt thereof, which can be used as a histone deacetylase inhibitor, has a selective inhibitory effect on HDAC6, and has characteristics such as a high efficiency, low toxicity and ideal pharmacokinetic properties.

Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

Abstract: Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.

Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

Abstract: The present application relates to the technical field of lifting equipment, and provides a traction machine and a lifting equipment. The traction machine includes traction pulleys, traction ropes driven by the traction pulleys and fixed pulleys for changing directions of the traction ropes. The fixed pulley is provided with a sensor sensing member rotating with the fixed pulley, a traction machine sensor is arranged beside the fixed pulley; the traction machine sensor is configured to detect a rotation speed of the sensor sensing member, and send the rotation speed to a controller of the traction machine; the controller controls a rotation of the traction pulley according to detected data of the traction machine sensor. Since this kind of traction machine is provided with the sensor sensing member and the traction machine sensor, it is capable of detecting whether the traction machine has an abnormal operation, and stopping the traction machine immediately in an abnormal state.

Abstract: An aqueous polymer dispersion and an aqueous coating composition comprising such aqueous polymer dispersion that shows good F/T stability and satisfactory anti-clogging properties and provides coatings with good hydrophobic stain resistance.

Abstract: A stable aqueous dispersion of multi-stage polymeric particles comprising a polymer and an oligomer, and an aqueous freeze-thaw stable coating composition comprising the aqueous dispersion providing coatings made therefrom with acceptable scrub resistance.

Abstract: An aqueous polymer composition comprising an acetoacetoxy functional polymer, a metal pyrithione compound, and TEMPO and/or its derivative, showing less yellowing.

Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

Abstract: The present invention provides an aqueous dispersion as a biobased binder and an aqueous coating composition comprising such aqueous dispersion and showing balanced stain resistance, freeze-thaw stability, and anti-clogging properties.

Abstract: The methods of gate extraction and injection FET and channel carrier quantity control related to microelectronics technology and semiconductor technology. The gate extraction and injection FET of the invention is provided with a source, a drain, a gate and a channel semiconductor area on the insulating layer. A gate dielectric layer is arranged between the gate and the channel semiconductor region, wherein, the gate dielectric layer is a thin film material with resistance values of 103-1016? and the channel semiconductor region is a two-dimensional semiconductor or a three-dimensional semiconductor with two-dimensional semiconductor material characteristics (1-10 cellular crystal layers). The advantages of the invention are that the power consumptions of the devices and the integrated circuits can be greatly reduced by a few orders of magnitude.

Abstract: A multistage aqueous emulsion polymer comprising from 88% to 98% by dry weight, based on total dry weight of the multistage aqueous emulsion polymer, of a first polymer core; and from 2% to 12% by dry weight, based on total dry weight of the multistage aqueous emulsion polymer, of a second polymer shell, wherein the first polymer core and the second polymer shell each independently comprises, as polymerized units, one or more ethylenically unsaturated nonionic monomers, wherein the second polymer shell further comprises, as polymerized units, from 20% to 60% by dry weight, based on total dry weight of the second polymer shell, of an acid monomer, wherein said acid monomer is, as polymerized units, from 1.1% to 4.2% by dry weight, based on total dry weight of the multistage aqueous emulsion polymer. An aqueous coating composition comprising said multistage aqueous emulsion polymer.

Abstract: An aqueous coating composition having good freeze-thaw stability and providing coatings with good stain resistance.

Abstract: This invention generally relates to a coating composition which provides a coating film with high hydrophilic resistance and high hydrophobic resistance. The coating composition contains a polymer formed from a monomer composition comprising (a) 45-85 wt % of ethyl ester of acrylic acid or methacrylic acid and (b) 15-54 wt % of itaconic ester with 1 or 2 carbon atoms as a binder of the coating composition, and the weight of sum of (a) and (b) is 65% or more based on the total weight of the polymer.

Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.