Abstract: The present invention relates to a polymer dispersion of polymer particles comprising phosphorous-containing (meth)acrylate monomers and phosphorus-containing allylic monomers. The present invention further relates to a coating composition made from the polymer dispersion with both satisfactory coating viscosity stability and improved coating performances such as scrub resistance, stain resistance, corrosion resistance and durability.

Abstract: The present invention provides a polymer dispersion comprising by dry weight based on total dry weight of the polymer dispersion, a) from 60% to 95% a vinyl acetate monomer, b) from 0.2% to 2.5% a phosphorus-containing allylic monomer; and c) from 0.2% to 2.5% an itaconic acid monomer; wherein the total amount of monomers b) and c) is from 0.5% to 2.5% by dry weight based on total dry weight of the polymer dispersion, and the dry weight ratio of monomer b) to monomers b) and c) is from 0.2 to 0.6. The present invention further provides a paint formulation of PVC higher than 60% comprising the polymer dispersion.

Abstract: The present invention relates to a polymer dispersion of polymer particles comprising phosphorous-containing (meth)acrylate monomers and phosphorus-containing allylic monomers. The present invention further relates to a coating composition made from the polymer dispersion with both satisfactory coating viscosity stability and improved coating performances such as scrub resistance, stain resistance, corrosion resistance and durability.

Abstract: Provided is a process for forming forming an antimicrobial polymer composition comprising: contacting together at least one initiator, at least one promoter, at least one reductant, and at least one monomer, under emulsion polymerization conditions to form a base polymer; and mixing with the base polymer an antimicrobial complex; wherein the at least one initiator is a peroxidic compound and the at least one reductant is an ascorbic compound.

Abstract: The present invention relates generally to an aqueous polymer dispersion and a coating composition made thereof, especially to a “green” antibacterial polymer dispersion with improved color stability property upon exposure to heat and/or light, and the coating composition made thereof.

Abstract: An aqueous coating composition having acceptable heat-age stability and providing the resultant coating film with good washability.

Abstract: Disclosed in the present invention is a novel histone deacetylase inhibitor of benzamides and use thereof. The inhibitor has good efficacy in treating diseases caused by abnormal gene expression, such as tumors, endocrine disorders, immune system diseases, genetic diseases and nerve system diseases. The histone deacetylase inhibitor of benzamides is a compound of the following general chemical structural formula (I) or a salt thereof.

Abstract: The present invention provides a 4-aminoquinazoline derivative having the chemical structure of the following formula, and the use thereof. It is demonstrated by the pharmacological experiment that, the compound or a salt thereof according to the present invention not only has distinct inhibitory effect on histone deacetylases, but also has stronger differentiation induction and anti-proliferative activities for certain tumor cells. It can be used in the treatment of cancers and diseases related to cell differentiation and proliferation. Excellent efficacy is observed especially for leukemia and a solid tumor. As demonstrated by the animal test, the compound or a salt thereof according to the present invention is less toxic.

Abstract: An aqueous antibacterial polymer emulsion and coating compositions are provided. The aqueous antibacterial polymer emulsion comprising a polymer A, an oxidant and a metal complexed with a copolymer B comprising heterocyclic containing monomers; wherein the metal is selected from copper, silver, gold, tin, zinc and combinations thereof; and wherein the emulsion is heat stable. The coating compositions made therefrom provide persistent, broad spectrum antibacterial activity without discoloration problem upon exposure to heat and/or sun light.

Abstract: A method for producing an AB block copolymer with PDI is provided. The method comprises steps of: 1) reaction, in the presence of at least one free radical initiator, of a reaction mixture comprising a compound of formula (I), and 2) reaction, at a temperature of 45° C. or above, of a reaction mixture comprising an ethylenically unsaturated monomer B and, independent from that of step 1), a compound of formula (I) and the macroinitiator of step 1) in solvent(s) to obtain the AB block copolymer; wherein the weight ratio of the compound of formula (I) to the macroinitiator in step 2) is at least 1:1000.

Abstract: The present invention provides a 4-aminoquinazoline derivative having the chemical structure of the following formula, and the use thereof. It is demonstrated by the pharmacological experiment that, the compound or a salt thereof according to the present invention not only has distinct inhibitory effect on histone deacetylases, but also has stronger differentiation induction and anti-proliferative activities for certain tumor cells. It can be used in the treatment of cancers and diseases related to cell differentiation and proliferation. Excellent efficacy is observed especially for leukemia and a solid tumor. As demonstrated by the animal test, the compound or a salt thereof according to the present invention is less toxic.

Abstract: Disclosed in the present invention is a novel histone deacetylase inhibitor of benzamides and use thereof. The inhibitor has good efficacy in treating diseases caused by abnormal gene expression, such as tumours, endocrine disorders, immune system diseases, genetic diseases and nerve system diseases. The histone deacetylase inhibitor of benzamides is a compound of the following general chemical structural formula (I) or a salt thereof.

Abstract: The present invention relates generally to an aqueous polymer dispersion and a coating composition made thereof, especially to a “green” antibacterial polymer dispersion with improved color stability property upon exposure to heat and/or light, and the coating composition made thereof.

Abstract: The present application relates to calcium channel inhibitors comprising compounds of formula (I), formula (II), formula (III), or formula (IV), wherein L1, R1, R2, R3, R4, R5, R6, R7 and Rc are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

Abstract: The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein Z1, Z2, Z3, Z4, R1, R2, and R3 are as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use as calcium channel inhibitors.

Abstract: The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein Z?, Z?, L2, G2, R1, and R2 are as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use as calcium channel blockers.

Abstract: The present application relates to calcium channel inhibitors comprising compounds of formula (I), formula (II), formula (III), or formula (IV), wherein L1, R1, R2, R3, R4, R5, R6, R7 and Rc are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

Abstract: In a hepatic disease-evaluating apparatus, an indicator calculating unit calculates an index indicating the degree of hepatic fibrosis from amino acid concentration data to be evaluated including amino acid concentration value, based on one or more indices of fractional expression having amino acid concentration as variable. A disease state evaluating unit evaluates the disease state of the hepatic disease to be evaluated, based on the index value.

Abstract: A method for producing an AB block copolymer with PDI is provided. The method comprises steps of: 1) reaction, in the presence of at least one free radical initiator, of a reaction mixture comprising a compound of formula (I), and 2) reaction, at a temperature of 45° C. or above, of a reaction mixture comprising an ethylenically unsaturated monomer B and, independent from that of step 1), a compound of formula (I) and the macroinitiator of step 1) in solvent(s) to obtain the AB block copolymer; wherein the weight ratio of the compound of formula (I) to the macroinitiator in step 2) is at least 1:1000.

Abstract: The present application relates to calcium channel inhibitors comprising compounds of formula (I), formula (II), formula (III), or formula (IV), wherein L1, R1, R2, R3, R4, R5, R6, R7 and Rc are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.