Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

Abstract: The data acquisition device may include a fat-suppression pulse exertion module configured to exert a fat-suppression pulse on an imaging area at set intervals, the fat-suppression pulse being able to suppress an initial fat signal to a negative value and keep the fat signal corresponding to the intermediate echo datum of the echo data collected between two fat-suppression pulses within [0, a], and a being a preset threshold close to 0, and an excitation and acquisition module, configured to exert a radio frequency pulse train and a series of phase encoding gradients after each fat-suppression pulse, collect the corresponding echo data, and fill the echo data into K-space in linear filling mode.

Abstract: Embodiments are disclosed for generating tables from charts. The techniques include determining a chart type of a selected chart. The techniques include determining a plurality of chart elements of the selected chart. Further, the techniques include determining a plurality of measurements of a plurality of data representations of the selected chart. Additionally, the techniques include determining a plurality of corresponding numeric values for the measurements based on the chart elements. Also, the techniques include generating a data table comprising the chart elements and the corresponding numeric values.

Abstract: The present disclosure related to techniques for extracting a respiratory navigation signal for use in a magnetic resonance imaging system. The extracted respiratory navigation signals accurately represent respiratory motions of a patient.

Abstract: An inspection system is configured to inspect the condition of a braze joint formed within a structure, wherein the braze joint is formed from a braze filler material having a tracer material disposed therein. The inspection system includes an energy source for directing energy towards the structure, an energy detector for detecting information regarding the structure following interaction with the energy directed from the energy source, and a data analysis system for analyzing the information detected by the energy detector. The data analysis system is configured to distinguish the tracer material from the remaining materials forming the structure in order to determine a suitability of the braze joint.

Abstract: A method for protecting content of online conversational content. The method provides for scanning content of an online conversational exchange between a first device and a second device. A sensitive object included in the content of the online conversation exchange is identified, based on object type information accessible from a protection policy included in respective user profiles. A pseudonymized-object-holder is assigned to the identified sensitive object according to the protection policy of the respective user profiles, and the identified sensitive object identified in the content of the online conversation exchange and stored on both the first device and the second device is replaced with a pseudonymized-object-holder, based on the sensitive-object protection policy of the respective user profiles.

Abstract: Methods and systems are provided for sequence-to-sequence conversion from unstructured search queries to structured database queries, so that lay persons may retrieve information from relational databases without specialized knowledge of database query languages. An encoder module and a decoder module of a learning model are trained to convert an unstructured search query to an intermediate feature vector by computing co-attention and self-attention based on a context string and a database schema, encoding the database schema in the context string by application of self-attention between the context string containing tokens of the database schema with learned structural attention heads which relate the token to logic of the database. Training is performed using labeled training datasets which include structured database queries which are normalized by parsing into a semantic representation thereof, followed by linearization.

Abstract: The invention relates to the field of pharmaceutical chemistry. Specifically, the present invention relates to a series of BET (bromodomain and extra-terminal domain) inhibitors having a novel structure, particularly inhibitors targeting BRD4 (Bromodomain-containing protein 4), and a preparation method and use therefor. The structure thereof is shown in the following general formula (I). Said compounds or a stereoisomer, racemate, geometric isomer, tautomer, prodrug, hydrate, solvate, or crystal form thereof, or a pharmaceutically acceptable salt thereof, and the pharmaceutical composition thereof can be used for the treatment and/or prevention of related diseases mediated by bromodomain proteins.

Abstract: An apparatus for treating municipal sewage by anaerobic/aerobic/anoxic (AOA) [1] process via simultaneous endogenous partial [2] denitrification coupled with anammox in anoxic zone is disclosed. The apparatus mainly includes a raw water tank (1) for sewage, an AOA reactor (2) and a sedimentation tank (3), the sludge flows back from the bottom of the sedimentation tank (3) to the anoxic zone (2.4) and the anaerobic zone (2.2) respectively, and biofilm filler is added to the anoxic zone (2.4). The sewage enters the AOA reactor (2), and the intracellular carbon source is stored in the anaerobic zone (2.2) to remove the organic matter in the raw water. Then it enters the aerobic zone (2.3) for nitrification, and the generated nitrate-nitrogen enters the anoxic zone (2.4) for endogenous partial denitrification. The filler in the anoxic zone (2.4) uses the generated nitrite-nitrogen by endogenous partial denitrification and the remaining ammonia-nitrogen in the raw water to perform anammox reaction.

Abstract: A method for realizing heterotrophic and autotrophic coupling advanced nitrogen removal and simultaneous sludge reduction in an anaerobic-aerobic-anoxic sequencing batch reactor (AOA-SBR) is disclosed. Municipal sewage and sludge fermentation mixture is allowed to simultaneously enter into the AOA-SBR; in the anaerobic stage, the organic matter in the sewage and sludge fermentation mixture is converted into polyhydroxyalkanoates (PHA) and stored in the body; in the aerobic stage, the dissolved oxygen (DO) at 0.5˜1 mg/L is maintained by a real-time control, the aeration time is set for 1˜3 h, and when the mass concentration ratio of NO2?—N to NH4+—N is in a range from 1.5 to 2.

Abstract: A light-emitting diode is provided. The light-emitting diode includes a multiple quantum well structure to generate a light beam with a broadband blue spectrum. The light beam contains a first sub-light beam with a first wavelength and a second sub-light beam with a second wavelength. A difference between the first wavelength and the second wavelength ranges from 1 nm to 50 nm, and the light-emitting diode has a Wall-Plug-Efficiency (WPE) of greater than 0.45 under an operating current density of 120 mA/mm2.

Abstract: A light-emitting diode package component is provided. The light-emitting diode package component includes a substrate, a light-emitting chip, a die attach adhesive, a reflective structure, and a molding layer. The light-emitting chip is disposed on the substrate for generating an initial light beam with an initial wavelength. The die attach adhesive is disposed between the light-emitting chip and the substrate so that the light-emitting chip is mounted on the substrate. The reflective structure defining an accommodating space is disposed on the substrate and surrounds the light-emitting chip. The molding layer is disposed in the accommodating space and covers the light-emitting chip. The die attach adhesive includes a first wavelength conversion material, a portion of the initial light beam entering into the die attach adhesive excites the first wavelength conversion material to produce an excitation light with a first wavelength that is greater than the initial wavelength.

Abstract: In one embodiment, a system includes a processing circuit and logic integrated with the processing circuit, executable by the processing circuit, or integrated with and executable by the processing circuit. The logic is configured to cause the processing circuit to receive an expression sticker having metadata associated therewith and analyze the metadata to determine whether an augmented feature is specified by the metadata. The augmented feature is intended to be output in conjunction with display of the expression sticker. The logic is also configured to cause the processing circuit to output the expression sticker to a display of a first device and trigger a corresponding augmented unit of the first device to output the augmented feature in response to a determination that the augmented feature is specified by the metadata. Other systems, methods, and computer program products for augmented expression sticker management are described in accordance with more embodiments.

Abstract: A light emitting device is provided. The light emitting device includes a light emitting assembly having a first light emitting diode package structure and a second light emitting diode package structure. The light emitting assembly can generate a mixed light source having a spectral deviation index. The first light emitting diode package structure can generate a first light source having a first spectral deviation index. The second light emitting diode package structure can generate a second light source having a second spectral deviation index. When the first light source and the second light source are within a range from 460 to 500 nm, a sum of the first spectral deviation index and the second spectral deviation index is within a range from ?0.3 to 0.3, and a difference between the first spectral deviation index and the second spectral deviation index is at least greater than 0.2.

Abstract: A light emitting diode package structure is provided. The light emitting diode package structure includes first and second chips. A value of an intensity of a peak wavelength of a first shoulder wave of the first chip divided by an intensity of a peak wavelength of a first main wave of the first chip is defined as a first intensity ratio. A value of an intensity of a peak wavelength of a second shoulder wave of the second chip divided by an intensity of a peak wavelength of a second main wave of the second chip is defined as a second intensity ratio. The first and second chips satisfy “a difference between the intensities of the peak wavelengths of the first and second main waves being less than or equal to 2.5 nanometers” and “a difference between the first and second intensity ratios being greater than 0.1”.

Abstract: A cold plate assembly for cooling a battery of a vehicle includes a first exterior portion disposed adjacent the battery, a separator portion disposed adjacent the first exterior portion, a first flow path formed between the first exterior portion and the separator portion with the first flow path configured to receive a first fluid flow therein, a second exterior portion disposed adjacent the separator portion opposite the first exterior portion, and a second flow path formed between the separator portion and the second exterior portion with the second flow path configured to receive a second fluid flow therein. The first fluid flow flows relative to the second fluid flow in a counter-flow flow configuration.

Abstract: The present invention is related to the inhibition of the formation of Streptococci biofilms through the inhibition of glucosyl transferase (Gtf). Compounds, compositions and methods for inhibiting Streptococcus biofilm formation, as well as for preventing, inhibiting and/or treating the formation of dental caries, and methods of identifying compounds that prevent, inhibit and/or treat the formation of dental caries are provided.