Abstract: Disclosed are antibodies thereof that bind to coagulation factor XI (FXI) and/or its activated form factor XIa (FXIa), or to fragments of FXI and/or FXIa, and compositions containing the antibodies. Also disclosed are methods of preparing the antibodies and use of the antibodies for treating and/or preventing coagulation associated conditions such as thrombosis and complications or conditions associated with thrombosis.

Abstract: Provided are a data processing system and method based on dynamic redundancy heterogeneous encoding, and a device. The method comprises: respectively performing error correction encoding on information to be processed and a processing rule, so as to form encoded information to be processed and an encoded processing rule; processing, by using the encoded processing rule, the encoded information to be processed, so as to obtain response data; and then performing error correction decoding on N pieces of response data, so as to obtain processing result information of the information to be processed.

Abstract: Disclosed herein is a process for achieving a palladium-catalyzed cyclative C(sp3)-H/C(sp2)-H coupling reaction using a native free carboxylic acid as a directing group, an amino acid ligand, and oxidant. The process is useful for synthesizing a range of biologically important scaffolds, including tetralins, chromanes, and indanes.

Abstract: Provided are a method and apparatus for processing a deterministic networking (DetNet) data packet. The method includes: performing, by a DetNet node, format encapsulation on a data packet of a DetNet application flow when the DetNet application flow passes through a multiprotocol label switching (MPLS) network, wherein an encapsulated data packet comprises a label indication and a flow identifier header; and forwarding the encapsulated data packet in the MPLS network.

Abstract: A preparation method for a circuit board connection structure includes: providing a circuit board module that including a first outer wiring layer, and the first outer wiring layer including solder pads; forming a first pyrolytic adhesive layer and an inner wiring layer on the first outer wiring layer; forming a second pyrolytic adhesive layer and a second copper foil layer on the inner wiring layer; defining a plurality of through holes each configured to expose one of the solder pads; forming a copper plating layer on the second copper foil layer; etching the copper plating layer and the second copper foil layer to form a second outer wiring layer, thereby obtaining an intermediate body; heating and washing the intermediate body to remove the first pyrolytic adhesive layer and the second pyrolytic adhesive layer. The present application also provides a circuit board connection structure.

Abstract: Disclosed is a display panel including: first spacer on the array substrate, an orthographic projection of the first spacer on the array substrate being a first pattern extending along a first direction; a second spacer on the counter substrate, an orthographic projection of the second spacer on the array substrate being a second pattern extending along a second direction; at least two third spacers, orthographic projections of which on the array substrate being respectively on two sides of the first pattern along the first direction; at least two fourth spacers, orthographic projections of which on the array substrate being respectively on two sides of the second pattern along the second direction; one of the third spacer and the fourth spacer is on the array substrate, and the other is on the counter substrate.

Abstract: Disclosed herein is a process for making a compound of formula (2) by (hetero)aromatic C—H hydroxylation of a compound of formula (1): catalyzed by palladium(II) and a bidentate ligand in the presence of O2. The process is useful for instance, in the late-stage modification of medicinally important heterocycles.

Abstract: Provided herein is a method of forming a beta-lactone from a carboxylic acid having a beta-carbon with a hydrogen atom disposed thereon. The method comprises contacting a carboxylic acid of formula (1) as described herein with an effective amount of a palladium(II) catalyst, an effective amount of an N-protected aminoacid ligand, and t-butylhydroperoxide in a solvent comprising hexafluoroisopropanol (HFIP), at about 60° C. to provide a beta-lactone of formula (2) as described herein.

Abstract: An electronic device has a display substrate including a display area, a driver area, and a fan-out area. The fan-out area is divided to a plurality of fan-out regions, and has interconnects configured to access display elements formed on the display area. The driver area is adjacent to the fan-out area and configured to receive a driver chip having a plurality of pads. The interconnects of the fan-out area include a subset of first interconnects. Each first interconnect passes a first fan-out region and a second fan-out region to access a respective display element. A first portion of the subset of first interconnects is formed on the first fan-out region with a first interconnect pitch, and a second portion of the subset of first interconnects is formed on the second fan-out region with a second interconnect pitch different from the first interconnect pitch.

Abstract: A terminal includes a terminal body part and an electronic accessory part. A WI-FI antenna apparatus is disposed on the terminal body part. The WI-FI antenna apparatus has a closed slot antenna. The closed slot antenna has an antenna slot that includes a main straight slot and a first slot and a second slot that are separately bent with respect to two ends of the main straight slot and extend to a same side of the main straight slot. The first slot and the second slot are perpendicular to the main straight slot, and the electronic accessory part is located on a side surface of the main straight slot.

Abstract: An electronic device has a display screen and a driver chip disposed on a driver area of the display screen. A fan-out area of the display screen has interconnects configured to provide electrical accesses to display elements of the display area. The driver chip includes a first edge, a second edge, and a row of electronic pads proximate to the first edge. The electronic pads have a first subset of end pads at a first end of the first row, a second subset of end pads at a second opposite end of the first row, and a subset of intermediate pads located between the first subset and second subset of end pads. The first subset of end pads physically contact a first subset of interconnects from the first edge, and the subset of intermediate pads physically contact a second subset of interconnects from the one or more second edges.

Abstract: Palladium-catalyzed C(sp3)—H arylation of aliphatic carboxylic acids, amides and ketones with BNA-encoded aryl iodides in water is disclosed, Furthermore, sequential C—H arylation chemistry enabled the on-DNA synthesis of structurally-diverse scaffolds containing enriched C(sp3) character, chiral centers, cyclopropane, cyclobutane, and heterocycles. That new chemistry permits preparation of a DNA—encoded library (BEL) technology that can dramatically expedite hit identification in drug discovery owing to its ability to perform protein affinity selection with millions or billions of molecules in a single experiment. The sequential functionalization of multiple C—H bonds provides an unique avenue for creating diversity and complexity from simple starting materials. The use of water as solvent, the presence of DMA, and the extremely low concentration of DMA-encoded coupling partners (0.

Abstract: An electronic device has a display substrate including a display area, a driver area, and a fan-out area. The fan-out area has interconnects that provide electrical accesses to display elements on the display area. A driver chip is disposed on the driver area and includes a first edge adjacent to the display area, two side edges connected to the first edge, and a plurality of pad groups. Each pad group includes a row of electronic pads that are electrically coupled to a subset of display elements via a subset of interconnects routed on the fan-out area. The pad groups include a first pad group and a second pad group disposed immediately adjacent to the first pad group. A first subset of interconnects cross one of the two side edges, and extend above a gap between rows of the first and second pad groups to reach the first pad group.

Abstract: An electronic device has a display screen and a driver chip disposed on a driver area of the display screen. A fan-out area of the display screen has interconnects configured to provide electrical accesses to display elements of the display area. The driver chip includes a first edge, a second edge, and a row of electronic pads proximate to the first edge. The electronic pads have a first subset of end pads at a first end of the first row, a second subset of end pads at a second opposite end of the first row, and a subset of intermediate pads located between the first subset and second subset of end pads. The first subset of end pads physically contact a first subset of interconnects from the first edge, and the subset of intermediate pads physically contact a second subset of interconnects from the one or more second edges.

Abstract: Provided herein is a method of forming a beta-lactone from a carboxylic acid having a beta-carbon with a hydrogen atom disposed thereon. The method comprises contacting a carboxylic acid of formula (1) as described herein with an effective amount of a palladium(I) catalyst, an effective amount of an N-protected aminoacid ligand, and t-butylhydroperoxide in a solvent comprising hexafluoroisopropanol (HFIP), at about 60° C. to provide a beta-lactone of formula (2) as described herein.

Abstract: The present invention provides a polyformaldehyde composite material, in parts by weight, including the following components: 70 to 95 parts of a polyformaldehyde; 5 to 20 parts of a SEBS; wherein, the SEBS is acid modified or amine modified. Due to modification by acid or amine, and presence of a polystyrene segment, a compatibility of the SEBS with the polyformaldehyde reduces because of a steric hindrance effect, which reduces an ability of a POM molecular chain to arrange regularly. When injection molded into a product or template, an incompatibility of the material itself will form a micro-rough effect on a surface of the material. When an incident light reaches the micro-rough surface, a reflection direction of the light will change and thus a diffuse reflection occurs, and a low-gloss material is obtained.

Abstract: Disclosed is a force applying device for orthodontic treatment being elastically expandable and configured to generate a restoring force as an orthodontic force for an orthodontic treatment when compressed. The force applying device comprises a first element and a second element capable of moving relative to each other along a first axis. The force applying device for orthodontic treatment is compressed when the first and second elements move towards each other along the first axis. A first arm extends laterally from a first end of the first element away from the second element. A first connecting part of a first connector is fitted over the first arm. A second connecting part of the first connector is to be fitted over a button fixed on a first jaw to connect the first element to the first jaw. Both the first and the second connecting parts are toroidal in shape.

Abstract: The present invention provides a polypropylene-polyphenylene ether-polystyrene ternary alloy, including the following components in parts by weight: 100 parts of a polypropylene and a polyphenylene ether and a polystyrene, wherein the polypropylene accounts for 10% to 60%, the polyphenylene ether accounts for 10% to 60%, and the polystyrene accounts for 5% to 30%; 5 parts to 25 parts of a compatibilizer; and 10 parts to 60 parts of a polyphosphate compound. The polypropylene-polyphenylene ether-polystyrene ternary alloy of the present invention has an advantage of a less smoke release amount during melt.

Abstract: This application is directed to intra-panel communication in a touch display device in which a touch-integrated timing controller (TTCON) is coupled to touch-embedded source drivers (TSDs) via a plurality of forward links and a set of backward links. The forward links include a first subset of display forward links and a second subset of touch forward links. The TSDs are electrically coupled to a display panel including a plurality of display pixels and a plurality of touch sensors. The TTCON sends a display drive signal including display content data and display control data over the display forward links, and sends a touch control signal including an instruction to initiate an operation mode over the touch forward links. Upon receiving the touch control signal, the TSDs identify the instruction to initiate the operation mode, generate touch data accordingly, and return the touch data to the TTCON via the backward links.

Abstract: This application is directed to intra-panel communication in a touch display device in which a touch-integrated timing controller (TTCON) is coupled to touch-embedded source drivers (TSDs) via a plurality of forward links and a set of backward links. The forward links include a first subset of display forward links and a second subset of touch forward links. The TSDs are electrically coupled to a display panel including a plurality of display pixels and a plurality of touch sensors. The TTCON sends a display drive signal including display content data and display control data over the display forward links, and sends a touch control signal including an instruction to initiate an operation mode over the touch forward links. Upon receiving the touch control signal, the TSDs identify the instruction to initiate the operation mode, generate touch data accordingly, and return the touch data to the TTCON via the backward links.