Patents by Inventor Qun Gu

Qun Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190379328
    Abstract: The disclosed embodiments relate to the design of a system that implements an up-conversion mixer. This system includes a regulator-based linearized transconductance (gm) stage, which converts a differential intermediate frequency (IF) voltage signal into a corresponding pair of IF currents. It also includes a pair of current mirrors, which duplicates the pair of IF currents into sources of a set of switching transistors. The set of switching transistors uses a differential local oscillator (LO) signal to gate the duplicated pair of IF currents to produce a differential radio frequency (RF) output signal. Finally, a combination of capacitors and/or inductors is coupled to common source nodes of the set of switching transistors to suppress higher order harmonics in an associated common source node voltage signal.
    Type: Application
    Filed: June 5, 2019
    Publication date: December 12, 2019
    Applicant: The Regents of the University of California
    Inventors: Jinbo Li, Qun Gu
  • Patent number: 10426023
    Abstract: The disclosed embodiments relate to the design of a system that implements a coupling balance scheme for differential signals. The system includes a set of 2N signal lines carrying N differential signal pairs, wherein the set of 2N signal lines runs parallel to each other in a planar layout. The set of 2N signal lines is organized into a set of consecutive sequences, wherein each sequence includes a pattern of twists that switch signal positions for each differential pair to cancel coupling effects with respect to other signal lines. Moreover, the positions of differential signal pairs are exchanged between consecutive sequences, so that the set of consecutive sequences includes a sequence for each possible ordering of the N differential signal pairs.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: September 24, 2019
    Assignee: The Regents of the University of California
    Inventors: Jinbo Li, Qun Gu
  • Publication number: 20190271029
    Abstract: Disclosed herein is a method of covalently crosslinking DNA strands. In certain aspects, the method comprises incubating a hybridized, double-stranded DNA polynucleotide (dsDNA), comprising a probe strand that comprises an abasic (Ap) residue and an at least partially complementary target strand that comprises a 2?-deoxyadenosine (dA) residue, wherein incubation occurs under conditions that allow for a covalent crosslinking reaction to occur between the Ap residue in the probe strand and the dA residue in the target strand.
    Type: Application
    Filed: February 28, 2019
    Publication date: September 5, 2019
    Inventors: Kent Gates, Li-Qun Gu, Maryam Imani Nejad, Ruicheng Shi, Xinyue Zhang
  • Patent number: 10355678
    Abstract: The disclosed embodiments relate to the design of a high-speed frequency doubler circuit. During operation, the circuit uses a transformer-based balun to convert a single-ended input signal into a differential signal, wherein the transformer-based balun includes a transformer with a primary coil, which receives the single-ended input signal, and a secondary coil, which produces the differential signal. The transformer also includes a central compensation capacitor coupled between a center tap of the secondary coil and ground, wherein the central compensation capacitor acts to suppress common-mode components in the differential signal. Next, the circuit uses a pseudo-differential amplifier to convert the differential signal into a single-ended output signal, which has double the frequency of the single-ended input signal.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: July 16, 2019
    Assignees: The Regents of the University of California, California Institute of Technology
    Inventors: Yu Ye, Adrian J. Tang, Qun Gu, Brian J. Drouin
  • Patent number: 10273527
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: April 30, 2019
    Assignee: The Curators of the University of Missouri
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Patent number: 10205473
    Abstract: An error-feedback transmitter includes an input that receives an input signal, and an output that produces an output signal. It also includes an amplifier, located on a main path that carries a main signal between the input and the output. The transmitter includes a feedback path that carries a feedback signal from the output to the input, and a feedback-signal combiner, located on the main path between the input and the amplifier. The feedback-signal combiner negatively combines the feedback signal with the input signal to improve linearity in the output signal. The transmitter includes a feedforward path that carries a feedforward signal from the input toward the output, and a feedforward-signal combiner, located on the feedback path between the output and the feedback-signal combiner. The feedforward-signal combiner negatively combines the feedforward signal with the feedback signal to suppress components of the main signal in the feedback signal.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: February 12, 2019
    Assignee: The Regents of the University of California
    Inventors: Qun Gu, Jinbo Li
  • Publication number: 20190037222
    Abstract: A method of ultra-low rate video encoding, including capturing a frame within a video stream, capturing a global position of the frame, capturing a heading of the frame, linking the global position and the heading to the frame, determining a foreground of the frame based on the global position of the frame and the heading of the frame, determining an at least one region of interest within the foreground, analyzing the at least one region of interest, removing a background from the frame based on the global position and the heading, wherein the background is complementary to the foreground and encoding the foreground, the global position, the heading and the at least one region of interest.
    Type: Application
    Filed: March 20, 2018
    Publication date: January 31, 2019
    Inventors: QUN GU, JIZHANG SHAN
  • Publication number: 20190020366
    Abstract: An error-feedback transmitter includes an input that receives an input signal, and an output that produces an output signal. It also includes an amplifier, located on a main path that carries a main signal between the input and the output. The transmitter includes a feedback path that carries a feedback signal from the output to the input, and a feedback-signal combiner, located on the main path between the input and the amplifier. The feedback-signal combiner negatively combines the feedback signal with the input signal to improve linearity in the output signal. The transmitter includes a feedforward path that carries a feedforward signal from the input toward the output, and a feedforward-signal combiner, located on the feedback path between the output and the feedback-signal combiner. The feedforward-signal combiner negatively combines the feedforward signal with the feedback signal to suppress components of the main signal in the feedback signal.
    Type: Application
    Filed: November 30, 2017
    Publication date: January 17, 2019
    Applicant: The Regents of the University of California
    Inventors: Qun Gu, Jinbo Li
  • Patent number: 10075145
    Abstract: Methods and apparatuses for measuring a phase noise level in an input signal are disclosed. An input signal can be delayed to generate a delayed version of the input signal. Next, a phase difference can be detected between the input signal and the delayed version of the input signal. A phase noise level in the input signal can then be determined based on the detected phase difference. The measured phase noise level can then be used to suppress phase noise in the input signal.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: September 11, 2018
    Assignee: The Regents of the University of California
    Inventor: Qun Gu
  • Publication number: 20180234082
    Abstract: The disclosed embodiments relate to the design of a system that implements a coupling balance scheme for differential signals. The system includes a set of 2N signal lines carrying N differential signal pairs, wherein the set of N signal lines runs parallel to each other in a planar layout. The set of 2N signal lines is organized into a set of consecutive sequences, wherein each sequence includes a pattern of twists that switch signal positions for each differential pair to cancel coupling effects with respect to other signal lines. Moreover, the positions of differential signal pairs are exchanged between consecutive sequences, so that the set of consecutive sequences includes a sequence for each possible ordering of the N differential signal pairs.
    Type: Application
    Filed: February 7, 2018
    Publication date: August 16, 2018
    Applicant: The Regents of the University of California
    Inventors: Jinbo Li, Qun Gu
  • Publication number: 20180159516
    Abstract: The disclosed embodiments relate to the design of a high-speed frequency doubler circuit. During operation, the circuit uses a transformer-based balun to convert a single-ended input signal into a differential signal, wherein the transformer-based balun includes a transformer with a primary coil, which receives the single-ended input signal, and a secondary coil, which produces the differential signal. The transformer also includes a central compensation capacitor coupled between a center tap of the secondary coil and ground, wherein the central compensation capacitor acts to suppress common-mode components in the differential signal. Next, the circuit uses a pseudo-differential amplifier to convert the differential signal into a single-ended output signal, which has double the frequency of the single-ended input signal.
    Type: Application
    Filed: November 29, 2017
    Publication date: June 7, 2018
    Applicant: The Regents of the University of California
    Inventors: Yu Ye, Adrian J. Tang, Qun Gu, Brian J. Drouin
  • Patent number: 9978676
    Abstract: An interconnect is described that comprises an interconnect channel, and two channel couplers coupled to the two ends of the interconnect channel through respective stoppers that provide a gap between the channel couplers and the interconnect channel. Each channel coupler can comprise a coplanar waveguide, a microstrip line, and a patch-antenna based coupler. The interconnect can enable communication between integrated circuits using signal waves having a frequency between 100 GHz and 3 THz.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: May 22, 2018
    Assignee: The Regents of the University of California
    Inventors: Qun Gu, Xiaoguang Liu, Neville C. Luhmann, Jr., Bo Yu
  • Publication number: 20180002742
    Abstract: The present invention provides a new and improved multiplexed oligonucleotide detection method based on the nanopore technology with one or more probes containing a sequence with complementarity to the target oligonucleotide, a terminal extension at the probe's 3? terminus, 5? terminus, or both termini and a label attached to the terminus. The improved probes and probe sets enable sensitive, selective, and direct multiplex detection, differentiation and quantification of distinct target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method based on miRNA levels in the patient's tissue sample.
    Type: Application
    Filed: July 12, 2017
    Publication date: January 4, 2018
    Inventors: Li-Qun Gu, Xinyue Zhang
  • Publication number: 20170264261
    Abstract: Methods and apparatuses for measuring a phase noise level in an input signal are disclosed. An input signal can be delayed to generate a delayed version of the input signal. Next, a phase difference can be detected between the input signal and the delayed version of the input signal. A phase noise level in the input signal can then be determined based on the detected phase difference. The measured phase noise level can then be used to suppress phase noise in the input signal.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 14, 2017
    Applicant: The Regents of the University of California
    Inventor: Qun Gu
  • Patent number: 9732379
    Abstract: The present invention provides a new and improved multiplexed oligonucleotide detection method based on the nanopore technology with one or more probes containing a sequence with complementarity to the target oligonucleotide, a terminal extension at the probe's 3? terminus, 5? terminus, or both termini and a label attached to the terminus. The improved probes and probe sets enable sensitive, selective, and direct multiplex detection, differentiation and quantification of distinct target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method based on miRNA levels in the patient's tissue sample.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: August 15, 2017
    Assignee: The Curators of the University of Missouri
    Inventors: Li-Qun Gu, Xinyue Zhang
  • Patent number: 9667219
    Abstract: Methods and apparatuses for measuring a phase noise level in an input signal are disclosed. An input signal can be delayed to generate a delayed version of the input signal. Next, a phase difference can be detected between the input signal and the delayed version of the input signal. A phase noise level in the input signal can then be determined based on the detected phase difference. The measured phase noise level can then be used to suppress phase noise in the input signal.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: May 30, 2017
    Assignee: The Regents of the University of California
    Inventor: Qun Gu
  • Patent number: 9621152
    Abstract: A switch comprising a plurality of inductors and a plurality of shunt transistors is described. Each inductor can be electrically coupled between adjacent shunt transistors to form a distributed switch structure. At least two inductors in the plurality of inductors can be inductively coupled with each other. The plurality of inductors can correspond to portions of a coupling inductor, wherein the coupling inductor can have an irregular octagonal shape.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: April 11, 2017
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Ran Shu, Adrian J. Tang, Qun Gu, Brian J. Drouin
  • Patent number: 9574228
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: February 21, 2017
    Assignee: The Curators of the University of Missouri
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Publication number: 20170002403
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Application
    Filed: July 13, 2016
    Publication date: January 5, 2017
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Patent number: D836626
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: December 25, 2018
    Assignee: BEIJING RESEARCH & DEVELOPMENT CENTER OF CHINA AVIC AVIONICS SYSTEMS CO., LTD.
    Inventor: Qun Gu