Abstract: A first ultrasonic beacon transmission includes a first pilot signal and a first encoded information signal. An apparatus may detect the first pilot signal and decode, based on the first pilot signal, the first encoded information signal to identify a medical system associated with the first ultrasonic beacon transmission. Based on the first encoded information signal, the apparatus may enter into a first pairing state in which the apparatus is communicatively paired with the medical system. While the apparatus is operating in the first pairing state and within a threshold time of entering the first pairing state, the apparatus may detect a second pilot signal included in a second ultrasonic beacon transmission, which also includes a second encoded information signal. Based on the detection of the second pilot signal within the threshold time, the apparatus may continue operating in the first pairing state without decoding the second encoded information signal.

Abstract: A method includes displaying a plurality of computer-generated objects, and obtaining finger manipulation data from a finger-wearable device via a communication interface. In some implementations, the method includes receiving an untethered input vector that includes a plurality of untethered input indicator values. Each of the plurality of untethered input indicator values is associated with one of a plurality of untethered input modalities. In some implementations, the method includes obtaining proxy object manipulation data from a physical proxy object via the communication interface. The proxy object manipulation data corresponds to sensor data associated with one or more sensors integrated in the physical proxy object. The method includes registering an engagement event with respect to a first one of the plurality of computer-generated objects based on a combination of the finger manipulation data, the untethered input vector, and the proxy object manipulation data.

Abstract: A method includes, while displaying a computer-generated object at a first position within an environment, obtaining extremity tracking data from an extremity tracker. The first position is outside of a drop region that is viewable using the display. The method includes moving the computer-generated object from the first position to a second position within the environment based on the extremity tracking data. The method includes, in response to determining that the second position satisfies a proximity threshold with respect to the drop region, detecting an input that is associated with a spatial region of the environment. The method includes moving the computer-generated object from the second position to a third position that is within the drop region, based on determining that the spatial region satisfies a focus criterion associated with the drop region.

Abstract: Embodiments herein relate to a local assistant system responding to voice input using an ear-wearable device. The system detects a wake-up signal and receives a first voice input communicating a first query content. The system includes speech recognition circuitry to determine the first query content, speech generation circuitry, and an input database of locally-handled user inputs. If the first audio input matches one of the locally-handled user inputs, then the system takes a local responsive action. If the first audio input does not match one of the locally-handled user inputs, then the system transmits at least a portion of the first query content over a wireless network to a network resource.

Abstract: A system for near-surface geophysical subsurface imaging for detecting and characterizing subsurface heterogeneities comprises an instrument that outputs probing electromagnetic signals through a ground surface that interact and are affected by scattered signals of acoustic waves that travel through the ground surface and further senses vibrational modes of a subsurface below the ground surface; an imaging device that dynamically generates a time sequence of images of properties of the acoustic waves and maps elastic wave fields of the acoustic waves; and a processor that analyzes dynamic multi-wave data of the images to quantify spatial variations in the mechanical and viscoelastic properties of the subsurface.

Abstract: Aspects of subject technology provide systems and methods for generation and distribution of a stable identifier associated with multiple aliases of a user account. The stable identifier may be provided to various electronic devices by a server, responsive to requests associated with communications to those devices from one of the associated aliases. In this way, messaging applications can utilize the stable identifier to merge conversations from a single user having multiple aliases, and secure access to a secure device can be provided to an authorized user, even if the authorized user attempts access from an unauthorized account alias.

Abstract: Provided herein are combinations comprising difluoromethylornithine (DFMO), or an ionic form thereof, and a compound of the following structural formula: or a protonated form thereof, wherein values for the variables (e.g., a, b, c, d, e, n, R1, R2, X) are described herein. The combinations can provide combination drug therapy in a single pharmaceutical dosage form, and be used, for example, for the treatment of cancer.

Abstract: Disclosed herein is a multifunctional probe that may be inserted into tissue (e.g. brain tissue) that includes an optical waveguide, a microfluidic channel and a plurality of carbon nanofiber electrodes. In another embodiment, the probe includes a shank onto which carbon nanofiber electrodes are disposed. Also disclosed are methods of making disclosed probes.

Abstract: Examples include an apparatus for restraining an aircraft during engine acceleration, the apparatus including: a collet shaft that is configured to attach to the aircraft, a rod that is configured to attach to a runway, and a release mechanism that is configured to restrain the collet shaft to the release mechanism and configured to release the collet shaft in response to the release mechanism receiving an electric current.

Abstract: A system comprises a display configured to present a graphical user interface including a viewing area and one or more user interface elements. The system also comprises a gaze tracking device configured to detect a change in a gaze of a user while the user views the graphical user interface presented on the display. The system also comprises an audio input device configured to receive audio information. The system also comprises one or more processors configured to process the audio information received at the audio input device in accordance with a first mode to direct the received audio information as audio output to one or more audio output devices; and in response to the gaze tracking device detecting the change in the gaze of the user, process the received audio information in accordance with a second mode, the second mode being distinct from the first mode.

Abstract: A system for near-surface subsurface imaging for detecting and characterizing subsurface heterogeneities comprises a non-contact acoustic source that senses a plurality of acoustic waves that travel through a surface; an instrument that outputs probing electromagnetic signals through the surface that interact and are affected by scattered signals of the acoustic waves and further senses vibrational modes of a subsurface below the surface; an imaging device that dynamically generates a time sequence of images of properties of the acoustic waves and maps elastic wave fields of the acoustic waves; and a processor that analyzes dynamic multi-wave data of the images to quantify spatial variations in the mechanical and viscoelastic properties of the subsurface.

Abstract: Provided herein are methods of treating cancer, comprising administering AMXT 1501, or a pharmaceutically acceptable salt thereof, orally, and difluoromethylornithine (DFMO), or a pharmaceutically acceptable salt thereof, intravenously to a subject in need thereof.

Abstract: A method comprises displaying an image of an environment on a graphical user interface, the environment including personnel elements visible in the image, detecting a gaze of a user directed at an image of a first personnel element corresponding to a first information conveyor of a plurality of information conveyors, changing a state of the first information conveyor corresponding to the first personnel element from a passive state to a listening state in response to detecting that the gaze is directed at the image of the first personnel element, wherein the first information conveyor includes a first audio output device, receiving audio information through an audio input device, and when the state of the first information conveyor is changed to the listening state, controlling an output operation, wherein the output operation includes directing the received audio information as an audio output through the first audio output device.

Abstract: Disclosed herein are pharmaceutical salts of a cationic protonated polyamine pharmaceutical agent and an anionic organic carboxylate which is hydrophobic when in protonated form, particularly suited for oral administration, where these salts have good bioavailability in solid dosage forms and may be used in the treatment of cancer and other medical conditions for which the pharmaceutical agent is intended.

Abstract: A device pairing system is configured to determine that an auxiliary device detects an ultrasonic beacon emitted by a beacon generator and identify, in response to the determination that the auxiliary device detects the ultrasonic beacon, a medical system associated with the ultrasonic beacon. The auxiliary device is further configured to communicatively pair, in response to the identification of the medical system, the auxiliary device with the identified medical system.

Abstract: Examples include an apparatus for restraining an aircraft during engine acceleration, the apparatus including: a collet shaft that is configured to attach to the aircraft, a rod that is configured to attach to a runway, and a release mechanism that is configured to restrain the collet shaft to the release mechanism and configured to release the collet shaft in response to the release mechanism receiving an electric current.

Abstract: In order to facilitate product development, such as pharmaceutical product development, a computer implemented method and an apparatus are proposed that enable formulators to develop robust drug formulations in a cost- and time-efficient manner. To start the development process, the user selects the preferred dosage form (e.g., granules, pellets, capsules, tablets etc.), defines a target profile (e.g., amount of active ingredient per unit, size of dosage form, mechanical strength of dosage form, desired release behaviour etc.) and enters key characteristics of the active ingredient (e.g., true density, particle size distribution data, bulk and tapped density, angle of repose, compressibility and compactibility profile etc.). The identity (e.g., chemical name or structure) of the active ingredient is not necessarily disclosed. The apparatus processes the provided data and calculates key parameters of the AI (e.g.

Abstract: Disclosed herein are pharmaceutical salts of a cationic protonated polyamine pharmaceutical agent and an anionic organic carboxylate which is hydrophobic when in protonated form, particularly suited for oral administration, where these salts have good bioavailability in solid dosage forms and may be used in the treatment of cancer and other medical conditions for which the pharmaceutical agent is intended.

Abstract: A device providing inter-device call continuity facilitated by a wireless audio output device may include a processor configured to initiate, over a peer-to-peer connection with a second device, a communication session between the second device and a third device. The processor may be further configured to establish, over the peer-to-peer connection with the second device, an audio link corresponding to the communication session. The processor may be further configured to determine, based at least in part on the audio link, that a connection quality of the peer-to-peer connection satisfies a connection degradation condition. The processor may be further configured to request, over a wide area network connection, for the communication session with the third device to be handed-off from the second device to the first device, and to establish, over the wide area network connection, the communication session with the third device.