Abstract: A method of promoting travel includes the step of providing a website for promoting travel destinations for access by subscriber consumers and compiling promotional offers of all participating entities by travel destination. The method further includes allowing the subscriber consumer to select a travel destination and a promotional offer of interest. Further, the method includes sending the selected promotional offer to the subscriber consumer by means of text messaging on a mobile communication device of the subscriber consumer or customer.

Abstract: A method of simplified rebate redemption for a good or service purchased by a consumer comprises using a mobile communication device of a consumer to complete the rebate redemption. Preferably the mobile communication device utilized is a mobile telephone having text messaging capability. Thus, the method includes sending a receipt, bar code information and redemption offer information to the entity offering the rebate using the text messaging capability of a mobile telephone of a consumer purchasing the good or service for which the rebate is offered.

Abstract: A communication device comprises a transmitter, a receiver and a bar code reader. In one embodiment the communication device comprises a combined or integrated mobile telephone and bar code reader. Further, a method is provided for promoting the sale of a selected good or service. The method comprises the steps of receiving a bar code for a selected good or service from the communication device of the consumer and sending a coupon for the selected good or service to the communication device of the consumer.

Abstract: Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.

Abstract: A method of marketing includes steps of providing a business with a mobile phone text messaging service, providing a medium for a customer to join that text messaging service, creating and maintaining a list of customers for the business and sending a communication to at least one of the customers.

Abstract: An absorption spectroscopy gauge to measure chemical concentrations in a post-detonation combustion cloud of energetic materials. A broadband light source coupled to an optical fiber guides light into a gauge via a first leg where a plano-convex lens collimates the light source internally. The light reflects off a mirror and passes through an absorption region before entering a second leg of the gauge where it is refocused into a different fiber and sent to a time-resolved spectroscopy system for analysis. The time-resolved spectroscopy system can include a spectrometer and a steak camera. The two legs of the gauge are arranged as separate halves connected by a plurality of rods that can be adjusted to change the length of the absorption region. The gauge is arranged to include stainless steel cone shaped tips to minimize added turbulence brought upon by its use.

Abstract: Hydrocarbon containing formations can be processed using an in-situ liquefaction technique. This new technique embodies systematic temperature elevation applied to subsurface formation allowing recoverable hydrocarbons to reach a Newtonian fluid viscosity suitable for extraction.

Abstract: The invention provides novel compounds that may be used as intermediates in the preparation of epothilones, epothilone analogs and derivative, as well as new synthetic methods for producing the intermediates and products.

Abstract: An exemplary method for monitoring neonate brain function includes processing electroencephalographic data of the neonate to calculate at least one measure, the at least one measure including a non-linear measure, comparing the calculated at least one measure against at least one baseline threshold, wherein the at least one baseline threshold corresponds to a neonate age range, and outputting a result of the comparison. An exemplary system for monitoring neonate brain function includes a computing device for processing electroencephalographic data of the neonate to calculate at least one measure, the at least one measure including a non-linear measure, and for comparing the calculated at least one measure against at least one baseline threshold, wherein the at least one baseline threshold corresponds to a neonate age range, and a display for displaying a result of the comparison.

Abstract: Hydrocarbon containing formations can be processed using an in-situ liquefaction technique. This new technique embodies systematic temperature elevation applied to subsurface formation allowing recoverable hydrocarbons to reach a Newtonian fluid viscosity suitable for extraction.

Abstract: Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.

Abstract: Migrastatin and a migrastatin analog can be produced by fermentation of Streptomyces platensis NRRL 18993 and used in pharmaceutical formulations to treat cancer and/or inhibit metastasis of cancer cells.

Abstract: This invention relates to compounds of formula (I) and to pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, W, X, Y, and Ar are as defined herein. Compounds of formula (I) are useful in the treatment of diseases or conditions characterized by cellular hyperproliferation. This invention also relates to means for the preparation of compounds of formula (I); formulations containing compounds of formula (I); and methods for the use of said compounds and formulations in the treatment of a disease or condition characterized by cellular hyperproliferation, including cancer.

Abstract: A method and apparatus for laser drilling a vibrating workpiece. A laser is mounted to a stationary frame. A separate machine having a separate machine frame has a spherical lens mounted to the top of the machine frame in proximity to a workpiece engaged by the machine. The vibrations of the machine caused by operation are transmitted to the lens and workpiece. A laser beam emitted by the laser is transmitted thought the lens and focused on the workpiece.

Abstract: This present invention relates to compounds of formula (I) and to pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, W, X, Y, and Ar are as defined herein. Compounds of formula (I) are useful in the treatment of diseases or conditions characterized by cellular hyperproliferation. This invention also relates to means for the preparation of compounds of formula (I); formulations containing compounds of formula (I); and methods for the use of said compounds and formulations in the treatment of a disease or condition characterized by cellular hyperproliferation, including cancer.

Abstract: The present invention relates to compounds of the formula: 1

Abstract: An apparatus is disclosed for preparing a quantity of individual treated fibers from one or more fiber mats. The apparatus comprises a fiber treatment zone, and a conveyor for conveying each mat through the fiber treatment zone. In the treatment zone each mat is impregnated by an applicator with a treatment material, such as a crosslinking substance, and conveyed directly to an attrition device. The attrition device fiberizes the mats to form a fiber output having a low nit level, such as no more than about three, and a dryer both dries the fiber output and cures the crosslinking substance. The fiberizer is configured to minimize the accumulation of fiber at locations therein. Fiber is transported from the attrition device to the dryer at a high velocity under reduced pressure to promote drying. A heated retention bin is provided after drying to increase curing time in the system. A thermobonding agent may be added to the dried and cured fibers to enhance the wet strength of webs made from the fiber.

Abstract: An adaptive security system having a hierarchy of security servers. The security system maintains a primary security server for each task or process executing within a computing environment. An enforcement mechanism receives resource requests from the tasks and queries the corresponding primary security server which resolves the request based on a set of security associations. If the primary security server is unable to resolve the request, the enforcement mechanism queries a parent security server. Security servers are dynamically created and terminated in response to changing organizational policies. The present invention facilitates the dynamic creation and termination of security servers to adapt to organizational policy changes.

Abstract: A wireless system architecture whereby high efficiency broadband transceiver systems can be deployed at an initial build out stage of the system in a cost-efficient manner. A home base station location is identified within each cluster of cells and rather than deploy a complete suite of base station equipment at each of the cells in the cluster, inexpensive translator units are located in the outlying cells serviced by the home base station in which low traffic density is expected. The translators are connected to directional antennas arranged to point back to the home base station site. The translators are deployed in such a way which meshes with the eventually intended frequency reuse for the entire cluster of cells. The translator to base station radio links operate in-band that is, within the frequencies assigned to the service provider. The available frequency bands are divided into at least two sub-bands, with frequency translations ocurring entirely within a given sub-band.

Abstract: A wireless communication system basestation making use of a wideband, multichannel digital transceiver having incorporated therein a time division multiple-access (TDM) bus for providing digital samples of a plurality of wireless communication channels, wherein the TDM bus is used as a cross-bar switch to permit dynamic allocation of modulator and demodulator signal processing resources. The invention allows various standards, even those having different channel bandwidths, to be serviced by the same basestation, with automatic redistributed of signal processing resources, eliminating the need to reconfigure the basestation when the loading of different types of wireless signaling traffic changes.