Abstract: A knotless interference or contact fixation anchor assembly comprising an anchor body with a removable inserter/driver that fully supports the suture anchor over its entire working length. The anchor body may also incorporating a suture trap that is housed within a proximal eyelet of the anchor body. The anchor body may include a plurality of elongate ribs extending longitudinally along at least a portion of the anchor body. The plurality of ribs comprise flexible barbs. When inserted into bone or a bone tunnel, the barbs compress slightly, resulting in less bone compression around the anchor due to the forces required for insertion, and increased pull-out resistance.

Abstract: In one aspect, the invention relates to compositions comprising BCR-ABL tyrosine kinase inhibitors and artemisinin analogs, derivatives thereof, or related compounds, which are useful as in treating Philadelphia chromosome positive leukemias; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with BCR-ABL dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A hydrocarbon processing plant, such an LNG plant, is disclosed. A piperack structure has a major axis parallel to the major axis of the train with which it is associated. A first multipurpose module, substantially pre-assembled prior to being transported to an operating location, has a major axis that is either parallel or perpendicular to the major axis of the piperack. The first multipurpose module contains: process components that perform a function related to hydrocarbon processing or handling; piping systems that connect the process components directly to a second module that is adjacent the first multipurpose module, and wherein at least part of the piping systems are aligned with the major axis of the piperack structure; and at least one heat exchanger located in the first multipurpose module and operationally connected to process components in the hydrocarbon processing plant.

Abstract: A method of processing natural gas to produce liquefied natural gas using a consolidated refrigeration and liquefaction module. The natural gas is cooled in a first array of one or more heat exchangers using a first refrigerant from a first refrigerant circuit, wherein the first refrigerant is compressed in a first compressor. A second refrigerant from a second refrigerant circuit is compressed in a second compressor. The second refrigerant is cooled and partially condensed using the first refrigerant in a second array of one or more heat exchangers located in the consolidated refrigeration and liquefaction module. The partially condensed second refrigerant is separated into liquid and vapor phases using a refrigerant separator located in the consolidated refrigeration and liquefaction module. The natural gas is liquefied to produce LNG in a third array of one or more heat exchangers using the vapor and liquid phases of the partially condensed second refrigerant.

Abstract: The present invention provides polyolefin films comprising calcium carbonate that have a reduced moisture vapor transmission rate, methods of making the films, and packaging materials comprising the films.

Abstract: Embodiments of the invention include devices and methods for providing an anchor in tissue. An anchor of some embodiments is formed from strands of material combined together into a body and one or more elongated members extending from a distal end of the body that include one or more of the strands of material from which the proximal end of the body is formed. The elongated members may be pulled back through the body and pulled proximally relative to the body to laterally expand the body. Some embodiments may also use an inserter with a rod sized to fit in a cannula through the body of the anchor and a tube configured to provide a more rigid structure about the exterior of the anchor during insertion.

Abstract: The present invention provides polyolefin films comprising calcium carbonate that have a reduced moisture vapor transmission rate, methods of making the films, and packaging materials comprising the films.

Abstract: In one aspect, the invention relates to compositions comprising BCR-ABL tyrosine kinase inhibitors and artemisinin analogues, derivatives thereof, or related compounds, which are useful as in treating Philadelphia chromosome positive leukemias; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with BCR-ABL dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Aspects described herein pertain to restoring damaged portions of tooth or bone using plasma mediated deposition. In an embodiment, a biocompatible carrier gas is ionized to form a biocompatible atmospheric plasma stream. Restoration material, such as nano-scale powdered hydroxyapatite, is introduced into the plasma stream, which is then applied to a damaged portion of a bone or tooth. The restoration material is deposited on the damaged portion of the bone or tooth, thus restoring a shape and mechanical integrity of the bone or tooth.

Abstract: A strainer for removing debris from a fluid stream. The strainer includes a protective element, wherein the protective element comprises a flexible net configured to trap solids carried in a fluid stream, and a mount to hold the protective element within the fluid stream.

Abstract: The present invention is a dental device comprising natural and sustainable materials. These materials are derived from the nut of the tangua palm tree that may be fashioned into devices for human and animals when replacing one or more teeth of the subject.

Abstract: The present invention is a dental device comprising natural and sustainable materials. These materials are derived from the nut of the tangua palm tree that may be fashioned into devices for human and animals when replacing one or more teeth of the subject.

Abstract: The present invention provides a system and method to quarantine in the storage operating system and configuration information in which the storage operating system is stored in a designated partition on a removable nonvolatile memory device, such as a compact flash or a personal computer (PC) card that is interfaced with a motherboard of a filer system server. By providing for separate partitions, a failure or error arising during an upgrade to the storage operating system will not corrupt the other partitions.

Abstract: The present invention provides polyolefin films comprising calcium carbonate that have a reduced moisture vapor transmission rate, methods of making the films, and packaging materials comprising the films.

Abstract: The present invention provides a system and method to quarantine in the storage operating system and configuration information in which the storage operating system is stored in a designated partition on a removable nonvolatile memory device, such as a compact flash or a personal computer (PC) card that is interfaced with a motherboard of a filer system server. By providing for separate partitions, a failure or error arising during an upgrade to the storage operating system will not corrupt the other partitions.

Abstract: Novel compounds that have been found effective in inhibiting PDZ domain interactions, and particularly interactions of PDZ domains in MAGIs with the oncogenic (tumor suppressor) protein PTEN and interactions between the PDZ domain in the Dishevelled (Dvl) protein and other proteins such as the Frizzled (Fz) protein, have the general formula The invention also includes combinatorial libraries, arrays and methods for screening and studying proteins using such compounds. Compounds of the invention have produced apoptosis in certain cell lines that overexpress the Dishevelled protein (Dvl); inhibiting Wnt signaling.

Abstract: The present invention provides a system and method for diagnostics execution in which diagnostics code is stored in a designated partition on a removable nonvolatile memory device, such as a compact flash or a personal computer (PC) card that is interfaced with the motherboard of a file server system. The file server system firmware is programmed in such a manner that, upon receipt of a diagnostics command, a normal boot mechanism is interrupted, and a diagnostics boot is performed. The firmware is programmed to probe the removable nonvolatile memory device, and to load the diagnostics code contained thereon into main memory and to execute the diagnostics in response to an initiation by an operator's key sequence. In accordance with a further aspect of the invention, the data produced as a result of the diagnostics test sequence is captured and stored in a maintenance log in another partition on the compact flash that has been pre-assigned for that purpose.

Abstract: The invention provides compositions, pharmaceutical preparations and methods for activation of the ?F508 cystic fibrosis transmembrane conductance regulator protein (?F508 CFTR) that are useful for the treatment and study of cystic fibrosis (CF). The compositions and pharmaceutical preparations of the invention may comprise one or more tetrahydrobenzothiophene, benzofuran, pyramidinetrione, dihydropyridine, tetraahydrocarbazol or anthraquinone compounds (referred to as “activator compounds”). The invention provides methods increasing ion transport in a ?F508 CFTR in a cell by contacting the cell with an effective amount of an activator compound. In other embodiments, the invention also provides a method of treating a patient suffering from a ?F508 CFTR-mediated disease or condition, for example CF, by administering to the patient an efficacious amount of an activator compound. Kits for use in the subject methods are also provided.

Abstract: The present invention relates to compositions and methods for making recombinant heteromeric proteins using a protein complementation assay employing complementation pairs of selectable markers.

Abstract: The present invention provides a system and method for diagnostics execution in which diagnostics code is stored in a designated partition on a removable nonvolatile memory device, such as a compact flash or a personal computer (PC) card that is interfaced with the motherboard of a file server system. The file server system firmware is programmed in such a manner that, upon receipt of a diagnostics command, a normal boot mechanism is interrupted, and a diagnostics boot is performed. The firmware is programmed to probe the removable nonvolatile memory device, and to load the diagnostics code contained thereon into main memory and to execute the diagnostics in response to an initiation by an operator's key sequence. Data produced as a result of the diagnostics test sequence is captured and stored in a maintenance log in another partition on the nonvolatile memory.