Abstract: This invention provides a method of determining whether a nucleic acid molecule having a sequence of interest is present within a nucleic acid-containing sample which comprises the steps: (A) subjecting said nucleic acid of said sample to a treatment sufficient to fragment said nucleic acid and to produce a plurality of fragments derived from said nucleic acid; (B) fractionating said plurality of fragments; (C) contacting said fractionated plurality of fragments, under hybridizing conditions, with a reagent comprising a mixture of random or pseudorandom oligonucleotides, said oligonucleotides having a length a .gtoreq.3 and .ltoreq.

Abstract: An apparatus for measuring the angle of flexure between an elongated body limb and the portion of the body to which the limb is affected. The apparatus can be used to monitor flexure between a thigh and lower portion of a human leg. The apparatus is useful during the performance of rehabilitative knee-bends includes means for coupling the apparatus to the thigh, and two gravity actuated switches for monitoring the angle between a long axis of the thigh and vertical axis. The apparatus indicates when the extreme points of the knee-bend have been crossed.

Abstract: A pizza box lid has a plastic support device centrally mounted to its underside. The device has a mounting portion adhesively attached to the lid, and a post portion which is originally coplanar with the mounting portion and flat against the underside of the lid. The post portion has two panels, one of the two panels being hinged to the mounting portion and the other panel being hinged to the one panel. The entire support is formed from one homogeneous piece of material which is appropriately scored to define the hingedly connected mounting and panel portions. The post portion is folded about the hinge relative to the mounting portion and away from the lid to an erect position generally perpendicular to the lid, and then one panel is folded relative to the other panel so as to prop the panels perpendicular to the lid whereby they serve as a support post to prevent the lid from sagging when the lid is closed.

Abstract: A method for generating single-stranded nucleic acid molecules. The molecules contain nuclease resistant modified nucleotides, such that they are resistant to 5'.fwdarw.3' exonucleases.

Abstract: An apparatus for measuring the angle of flexure between an elongated body limb and the portion of the body to which the limb is affected. The apparatus can be used to monitor flexure between a thigh and lower portion of a human leg. The apparatus is useful during the performance of rehabilitative knee-bends includes means for coupling the apparatus to the thigh, and two gravity actuated switches for monitoring the angle between a long axis of the thigh and a vertical axis. The apparatus indicates when the extreme points of the knee-bend have been crossed.

Abstract: A retractable distributed array antenna has a multiplicity of radiative elements arranged in a beam-forming array of desired configuration and resolvable into a plurality C of columns, with each column having at least one of the antenna radiator elements. Each of a number P of elongated column members, up to but not exceeding C in number, supports the antenna elements of an associated column. The column members are arranged with their elongated dimension generally parallel to one another. The adjacent end portions of each pair of column member, or of a column member and a central stowage module, are joined by a spring-loaded hinge assembly, which urges the joined column member end portions away from each other, to place the columns of elements into the desired distributed array antenna configuration, if no retroactive forces are present.

Abstract: A passive transponder may be encoded with a number or code of up to 64 binary bits and then mounted to virtually any prosthesis implanted in a human, such as a breast implant. After implantation, the transponder's code may be conveniently read with a hand held electromagnetic reader which may merely be brought within proximity of the transponder. The encoded transponder may thus be read in a non-invasive procedure and without the use of any sophisticated or potentially harmful medical equipment or technology such as X-ray. The information encoded in the transponder may correspond to patient demographics and implant data to aid in tracking the implant's manufacturer and use for medical as well as legal reasons.

Abstract: An apparatus for measuring the angle A of flexure of a joint between longitudinal axes of adjacent, jointed body parts includes first and second coupling mechanisms for fixture respectively to the first and second body parts. Each of the coupling mechanisms is fixed to its respective body part at a specified distance from the joint being measured. The apparatus further includes a measuring device for generating a signal representative of the direct, linear distance between the coupling mechanisms as the joint passes through a range of motion. A computing device operates in response to the signal generated by the measuring device to determine the angle A in accordance with the law of cosines. An advantage of the apparatus is that it is significantly tolerant of improper placement of the coupling mechanisms.

Abstract: A method and apparatus for registering a sheet member with an indicia on the surface of a moving member which comprises means for driving a sheet member substantially tangentially of the moving member and between the moving member and a linear image sensor which is disposed adjacent the surface of the moving member. The linear image sensor senses the leading edge of the sheet member and, as the moving member is driven, the linear image sensor senses the passage of the indicia on the surface thereof as the member travels therepast. The distance between the indicia and the leading edge of the sheet member is sensed and an error signal is generated representative of the distance. The sheet member driving means is regulated so as to reduce the error signal and the sheet is attached to the moving member when the error signal is reduced to a predetermined value.

Abstract: Apparatus and method of producing image edge enhancement in four-color printers. The true black color is aligned for printing between the cyan, magenta, and yellow colors. When a black edge is desired, process black and true black are both used to produce the pixels along the edge. Because the process and true black pixels are interleaved with each other along the edge, the effective resolution is doubled and the sharpness is enhanced along the edge.

Abstract: A method and apparatus for producing neon and similar signs. The method includes a direct bending of glass tubing over a drawing which is protected by a translucent heat resistant sheet. The sheet and process for its production are also described.

Abstract: A seal elements of hard material for use, for instance, as a pair of small plates which form the parts to control the fluid flow through a faucet. The seal is constructed of a hard material--a metal, a metallic oxide, a metallic carbide, a metallic nitride, a ceramic or glassy material--which is sintered from a semi-finished product obtained by mixing a powder of fine particle size of the aforementioned hard materials with an organic binder--a plastic material, a wax, or a combination of these substances. This mixture is formed under compression in a mold and, eventually, at least some of the binder is eliminated.

Abstract: An interlocking door guard securely covers and is attached to the outside of doors that open inward. It uses a full length pendulum torsion rod assembly on the hinge side of the door as well as guides in connection therewith and matching receptacles in and/or on both vertical casing members to accommodate mating sections of door guard. The forward section has an open area adequate to access door locks. This area is further protected by adjustable guard bars. Hinge lever assemblies attached to the door and guard in the forward area cause it to shift and interlock and disengage both vertical casing members when encountering stop plates on forward casing receptacles.

Abstract: Derivatives of propranolol which have the following structure: ##STR1## where R is X--(CH.sub.2).sub.n --O, X is NH.sub.2 or COOH, n is 1,2,3,4, or 5, provided that when n is 1, X must be COOH, and R is attached in the 4',5',6',7' or 8' position. The compounds are useful in immunoassay applications to (1) conjugate to a protein carrier in order to prepare antibodies to propranolol and (2) to conjugate to a tracer moiety such as a radiolabeled ligand, an enzyme, an enzyme substrate or a fluorescent dye.

Abstract: Novel substituted phenyl eicosanoid analogs having the formula: ##STR1## and their pharmaceutically acceptable esters and salts, wherein: R is H or OH;R.sub.1 is H or lower alkyl;X is --CH.sub.2 --CH.sub.2 -- or cis --CH.dbd.CH--;Y is --CH.sub.2 --, ##STR2## --O-- or --S--; n is 0 or 1; and.circle.A is (1) an eicosanoid nucleus (ring system), (2) a carbocyclic analog of an eicosanoid nucleus or (3) a heterocyclic analog of an eicosanoid nucleus wherein one of the carbons in a carbocyclic analog is replaced by O, S or N.

Abstract: Derivatives of propranolol which have the following structure: ##STR1## where R is X--(CH.sub.2).sub.n --O, X is NH.sub.2 or COOH, n is 1,2,3,4, or 5, provided that when n is 1, X must be COOH, and R is attached in the 4', 5', 6', 7' or 8' position. The compounds are useful in immunoassay applications to (1) conjugate to a protein carrier in order to prepare antibodies to propranolol and (2) to conjugate to a tracer moiety such as a radiolabeled ligand, an enzyme, an enzyme substrate or a fluorescent dye.

Abstract: A water distribution system for a shower enclosure (1) including longitudinal water channels (20-24), each having an internal passage (36), and covering clips (60,70) secured to each of a pair of water channels at a corner therebetween.

Abstract: Apparatus for and a method of preforming into an elongate mold charge a gob of molten glass issuing from the outlet orifice of a forehearth and delivering such elongate charge to the forming cavity of a forming mold with the virgin or untouched surface of the charge facing downwardly in such cavity thereby providing to the mold cavity a mold charge having one or a lower surface of high optical quality. A mothering or serving cup receives said gob from said outlet orifice and is horizontally moved to spread or preform the gob into the elongate mold charge with the upper surface thereof being untouched, and the cup is then inverted to deliver the charge to a mold cavity with said upper surface of the gob facing downwardly.

Abstract: A method for augmenting hard or soft connective tissue, such as skin, tendon, cartilage, bone or interstitium, in a living mammal comprising implanting a proteolytic enzyme-solubilized, purified, native, in situ polymerizable collagen solution into the mammal at the augmentation site. The solution polymerizes at the site into a stable, non-reactive fibrous mass of tissue which is rapidly colonized by host cells and vascularized.