Patents by Inventor R. Richard Goehring

R. Richard Goehring has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aryl substituted pyridines and the use thereof
    Patent number: 7105549
    Abstract: This invention relates aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1–R4 are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: September 12, 2006
    Assignee: Euro-Celtique S.A.
    Inventors: Bin Shao, R. Richard Goehring, Samuel F Victory, Qun Sun
  • Tertiary amino compounds having opioid receptor affinity
    Patent number: 6984664
    Abstract: Disclosed are compounds of the formula (I) wherein R1, R2 R3 R4 R5, R6 and N are as disclosed herein. The compounds are useful for the treatment of chronic and acute pain.
    Type: Grant
    Filed: December 6, 2000
    Date of Patent: January 10, 2006
    Assignee: Euro-Celtique, S.A.
    Inventors: Donald Kyle, R Richard Goehring, Sam Victory
  • Benzimidazolone compounds
    Patent number: 6872733
    Abstract: Disclosed are compounds of the formula (I): wherein A, B, C, M1-M4, R, R1, R2 and n are as described herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 29, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: R. Richard Goehring, Zhengming Chen, Sam Victory, Donald Kyle
  • Nociceptin analogs
    Patent number: 6867222
    Abstract: A compound of the formula (I), (II), (III) or (IV) wherein Z, A, B, C, R, R1, R2, Q, and n are as described herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 15, 2005
    Assignee: Euro-Celtique, S.A.
    Inventors: Qun Sun, R. Richard Goehring, Donald Kyle, Zhengming Chen, Sam Victory, John Whitehead
  • Nociceptin analogs
    Patent number: 6861421
    Abstract: A compound of the having the general formula (I) or general formula (II): wherein Z, A, B, C, R1, R2, Q, W, and n are as described herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 1, 2005
    Assignee: Euro-Celtique S.A
    Inventors: R. Richard Goehring, Zhengming Chen, John Whitehead, Parviz Gharagozloo, Sam Victory, Donald Kyle
  • Spiroindene and spiroindane compounds
    Patent number: 6828440
    Abstract: A compound of the formula (I): wherein Z, A, B, C, R1, R2, X1, X2, Q and n are as disclosed herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: December 7, 2004
    Assignee: Euro-Celtique, S.A.
    Inventors: R. Richard Goehring, Sam Vicotry, Donald Kyle
  • Aryl substituted pyridines and their use
    Patent number: 6770661
    Abstract: This invention relates to aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1-R4 are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, including diabetic neuropathy, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, and as antiarrhythmics.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: August 3, 2004
    Assignee: Euro-Celtique S.A.
    Inventors: Bin Shao, R. Richard Goehring
  • Triazospiro compounds having nociceptin receptor affinity
    Publication number: 20040132757
    Abstract: Disclosed are compounds of the formula (I) 1
    Type: Application
    Filed: December 19, 2003
    Publication date: July 8, 2004
    Inventors: Donald Kyle, R. Richard Goehring
  • Spiropyrazole compounds
    Publication number: 20040087641
    Abstract: A compound of the formula (I): 1
    Type: Application
    Filed: June 19, 2003
    Publication date: May 6, 2004
    Applicant: Euro-Celtique
    Inventors: R. Richard Goehring, Gary Lee, Parviz Gharagozloo, Sam Victory, Donald Kyle
  • Triazospiro compounds having nociceptin receptor affinity
    Patent number: 6686370
    Abstract: Disclosed are compounds of the formula (I) wherein A, R1, R2, R3, R4 and X1 are as disclosed herein. The compounds have affinity for the ORL1 receptor and are useful in the treatment of chronic and acute pain.
    Type: Grant
    Filed: December 6, 2000
    Date of Patent: February 3, 2004
    Assignee: Euro-Celtique S.A.
    Inventors: Donald Kyle, R. Richard Goehring
  • Aryl substituted pyrimidines and the use thereof
    Publication number: 20030236273
    Abstract: This invention relates to a method of treating disorders responsive to the blockade of sodium ion channels using novel aryl-substituted pyrimidine compounds of Formula I: 1
    Type: Application
    Filed: March 13, 2003
    Publication date: December 25, 2003
    Applicant: Euro-Celtique S.A.
    Inventors: R. Richard Goehring, Sam F. Victory, Donald J. Kyle
  • Spiropyrazole compounds
    Patent number: 6635653
    Abstract: A compound of the formula (I): wherein Z, W, A, B, C, R1, R2, Q and n are as disclosed herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: October 21, 2003
    Assignee: Euro-Celtique S.A.
    Inventors: R. Richard Goehring, Gary Lee, Parviz Gharagozloo, Sam Victory, Donald Kyle
  • Aryl substituted pyridines and their use
    Publication number: 20030073724
    Abstract: This invention relates to aryl substituted pyridines of Formula I: 1
    Type: Application
    Filed: September 6, 2002
    Publication date: April 17, 2003
    Inventors: Bin Shao, R. Richard Goehring
  • Nociceptin analogs
    Publication number: 20030069249
    Abstract: A compound of the formula (I), (II), (III) or (IV) 1
    Type: Application
    Filed: April 18, 2002
    Publication date: April 10, 2003
    Inventors: Qun Sun, R. Richard Goehring, Donald Kyle, Zhengming Chen, Sam Victory, John Whitehead
  • Inhibitors of p38-a kinase
    Patent number: 6541477
    Abstract: The invention is directed to methods for treating conditions mediated by by P38&agr; kinase using compounds of the formula wherein Ar1 and Ph are limited to specific embodiments or wherein the compound of formula (3) is a compound set forth in FIGS. 1A-1T.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: April 1, 2003
    Assignee: Scios, Inc.
    Inventors: R. Richard Goehring, Babu J. Mavunkel, David Y. Liu, George F. Schreiner, Gregory Leudtke, John A. Lewicki
  • Aryl substituted pyridines and the use thereof
    Publication number: 20030055088
    Abstract: This invention relates aryl substituted pyridines of Formula I: 1
    Type: Application
    Filed: September 6, 2002
    Publication date: March 20, 2003
    Applicant: Euro-Celtique S.A.
    Inventors: Bin Shao, R. Richard Goehring, Samuel F. Victory, Qun Sun
  • Spiropyrazole compounds
    Publication number: 20030027834
    Abstract: A compound of the formula (I): 1
    Type: Application
    Filed: April 18, 2002
    Publication date: February 6, 2003
    Inventors: R. Richard Goehring, Gary Lee, Parviz Gharagozloo, Sam Victory, Donald Kyle
  • Spiroindene and spiroindane compounds
    Publication number: 20030018041
    Abstract: A compound of the formula (I): 1
    Type: Application
    Filed: April 18, 2002
    Publication date: January 23, 2003
    Inventors: R. Richard Goehring, Sam Vicotry, Donald Kyle
  • Nociceptin analogs
    Publication number: 20030013874
    Abstract: A compound of the having the general formula (I) or general formula (II): 1
    Type: Application
    Filed: April 18, 2002
    Publication date: January 16, 2003
    Inventors: R. Richard Goehring, Zhengming Chen, John Whitehead, Parviz Gharagozloo, Sam Victory, Donald Kyle
  • Benzimidazolone compounds
    Publication number: 20030008886
    Abstract: Disclosed are compounds of the formula (I): 1
    Type: Application
    Filed: April 18, 2002
    Publication date: January 9, 2003
    Inventors: R. Richard Goehring, Zhengming Chen, Sam Victory, Donald Kyle