Abstract: An application programming interface schema, method and system for communicating between first and second application programming interfaces within a process control system includes processing a call from a first application programming interface for a data request, translating the data request from the first application programming interface into one or more methods of a unified application programming interface, and implementing the one or more methods of the unified application programming interface with a second application programming interface. A first unified layer receives a transmission request from a proprietary application programming interface, and translates the transmission request into one or more methods of a unified application programming interface. A second unified layer implements methods of the unified application programming interface with the wireless network application programming interface.

Abstract: A method and system of communicating between a wireless network and a process control system communicatively coupled to a server via a process control system interface, such as OPC or a proprietary API. The wireless network may be a mesh network and the server may be a mesh server. The server receives data from the wireless network, where the data is generated from an input/output data point within the wireless network. The server maps the data between the input/output data point and a data point placeholder within the process control system. The server writes the mapped data to the corresponding data point placeholder of the process control system via the process control interface, and the mapped data is provided to the process control system as process control data native to the process control system.

Abstract: Antagonists of cation-independent mannose 6-phosphate/insulin-like growth factor-II receptor are provided for attenuation of CTGF signaling in a method of down-regulation of receptor signaling and downstream decreased signaling of connective tissue growth factor in ocular disorders involving inappropriate CTGF signaling. Ocular disorders involving inappropriate CTGF signaling include ocular hypertension, glaucoma, glaucomatous retinopathy, optic neuropathy, macular degeneration, diabetic retinopathy, choroidal neovascularization, and proliferative vitreoretinopathy, for example. Such disorders are treated by administering antagonists of the present invention.

Abstract: Antagonists of S1P3 (Edg-3) receptors are provided for attenuation of Smad signaling in a method of down-regulation of receptor signaling and downstream decreased production of connective tissue growth factor in ocular disorders involving CTGF accumulation. Ocular disorders involving inappropriate CTGF accumulation include ocular hypertension, glaucoma, glaucomatous retinopathy, optic neuropathy, macular degeneration, diabetic retinopathy, choroidal neovascularization, proliferative vitreoretinopathy and ocular wound healing, for example. Such disorders are treated by administering antagonists of the present invention.

Abstract: The disclosed system, device and method for spatial homogenization and focusing of electromagnetic radiation over an aperture to reduce the effects of atmospheric scintillation generally includes an optical lens having an at least partially undulating pattern mapped onto a curvilinear surface. Disclosed features and specifications may be variously controlled, adapted or otherwise optionally modified to eliminate or otherwise reduce the effects of atmospheric scintillation as well as other optical aberrations. Exemplary embodiments of the present invention generally provide improved systems and methods for the acquisition, tracking and engagement of military targets with missiles or other guided ordinance.

Abstract: A process is disclosed for releasing proteins from cells and/or inactivating viruses. In the process, a host cell containing a protein of interest is contacted with a solution of an effective amount of a detergent.

Abstract: Fabrication of microelectronic devices is accomplished using a substrate having a recessed pattern. In one approach, a master form is used to replicate a substrate having a pit pattern. In another approach, the substrate is produced by etching. A series of stacked layers having desired electrical characteristics is applied to the substrate and planarized in a manner that creates electrical devices and connections therebetween. The microelectronic devices can include a series of row and columns and are used to store data at their intersection.

Abstract: A communication technique enables the efficient transmission of data through a low bandwidth and/or time delayed communication link and minimizes the idle time of the communication link by using a deferred acknowledgment of message bundles to temporally pack the communication link. The transmitting system stores messages to be transmitted in a pending message queue and applies a dynamic window to the pending message queue to define a message bundle to be sent through the slow communication link. The transmitting system requests an acknowledgment for at least one message within the bundle, but does not require an acknowledgment for every message within the bundle. Transmitted messages are temporarily stored as outstanding messages in a retransmission queue until the transmitted messages are acknowledged or until a time-out period associated with the messages has lapsed.

Abstract: A communication technique enables the efficient transmission of data through a low bandwidth and/or time delayed communication link and minimizes the idle time of the communication link by using a deferred acknowledgment of message bundles to temporally pack the communication link. The transmitting system stores messages to be transmitted in a pending message queue and applies a dynamic window to the pending message queue to define a message bundle to be sent through the slow communication link. The transmitting system requests an acknowledgment for at least one message within the bundle, but does not require an acknowledgment for every message within the bundle. Transmitted messages are temporarily stored as outstanding messages in a retransmission queue until the transmitted messages are acknowledged or until a time-out period associated with the messages has lapsed.

Abstract: Fabrication of microelectronic devices is accomplished using a substrate having a recessed pattern. In one approach, a master form is used to replicate a substrate having a pit pattern. In another approach, the substrate is produced by etching. A series of stacked layers having desired electrical characteristics is applied to the substrate and planarized in a manner that creates electrical devices and connections therebetween. The microelectronic devices can include a series of row and columns and are used to store data at their intersection.

Abstract: An air knife constructed in accordance with the present invention directs a curtain of air across a region and most typically is used to direct the stream of air against a surface. In an exemplary embodiment of the invention the air knife includes an elongated housing having an inlet for receiving air into the housing. The housing includes an elongated gap that extends along the housing that allows air entering the housing through the inlet to exit the housing and form a curtain of air. The elongated housing is made from a piece of sheet metal bent to define a hollow region into which air is forced. The sheet metal defines a gap along a length of the housing from which the air exits. The elongated air knife forms an angle with respect to a direction of travel of glass sheets passing the air knife so that a leading edge of those glass sheets passes progressively different parts of the air knife.

Abstract: The present invention provides a method for recombinant production, recovery and purification of angiostatin protein. This method may be employed for large scale recovery and purification of recombinantly-produced angiostatin protein.

Abstract: The present invention relates to methods and processes of inactivating viral contaminants in a biological source material (e.g. a host cell, cell supernatant, cell lysate, blood plasma, tissue homogenate, or other biological materials) with a solution containing one or more alkylamine compounds. In a particular embodiment, the active ingredients are amphipathic, charged amines or amine oxides coupled to saturated hydrocarbon chains of varying lengths.

Abstract: The present invention relates to methods and processes of inactivating a viral contaminants in a biological source material or process intermediate by contacting the biological source material (e.g., a host cell, cell supernatant, cell lysate, blood plasma, tissue homogenate, or other biological materials) with a solution containing one or more alkylamine compounds. In a particular embodiment, the active ingredients are amphipathic, charged amines or amine oxides coupled to saturated hydrocarbon chains of varying lengths.

Abstract: Fabrication of microelectronic devices is accomplished using a substrate having a recessed pattern. In one approach, a master form is used to replicate a substrate having a pit pattern. In another approach, the substrate is produced by etching. A series of stacked layers having desired electrical characteristics is applied to the substrate and planarized in a manner that creates electrical devices and connections therebetween. The microelectronic devices can include a series of row and columns and are used to store data at their intersection.

Abstract: The present invention provides a method for recombinant production, recovery and purification of angiostatin protein. This method may be employed for large scale recovery and purification of recombinantly-produced angiostatin protein.

Abstract: The present invention relates to methods and processes of inactivating a viral contaminants in a biological source material or process intermediate by contacting the biological source material (e.g., a host cell, cell supernatant, cell lysate, blood plasma, tissue homogenate, or other biological materials) with a solution containing one or more alkylamine compounds. In a particular embodiment, the active ingredients are amphipathic, charged amines or amine oxides coupled to saturated hydrocarbon chains of varying lengths.

Abstract: Fabrication of microelectronic devices is accomplished using a substrate having a recessed pattern. In one approach, a master form is used to replicate a substrate having a pit pattern. In another approach, the substrate is produced by etching. A series of stacked layers having desired electrical characteristics is applied to the substrate and planarized in a manner that creates electrical devices and connections therebetween. The microelectronic devices can include a series of row and columns and are used to store data at their intersection.

Abstract: An apparatus for high speed attachment of a cord to a piece of receiving material is characterized by one or more pins which engage the cord, pierce the receiving material and draw the cord through the receiving material from the first side to a second side thereof so that open loops are formed in the cord on the second side of the receiving material. The pins may be implemented as a push pin and a spreader pin pair movably mounted relative to each other and each of which is adapted to grasp the cord and penetrate the receiving material. The loop(s) are formed as the push pin and spreader pin move relative to each other. The apparatus further comprises a floating shuttle, not attached to the frame of the apparatus but supported by a series of gear assemblies. The pins move relative to the shuttle in a single direction causing the shuttle to engage an end portion of the cord, drawing the cord through the open loops so as to complete the lacing stitch of the cord through the receiving material.