Abstract: A system for protecting access to digital documents may include a blockchain network and a stamp generation node. The stamp generation node may receive a digital document and access parameters from a first user node. A unique identifier for the document may be generated and recorded on the blockchain with the access parameters. A QR code encoding a URL for accessing the document may be generated and embedded in the document. A shortened URL corresponding to the encoded URL may be generated and transmitted to a second user node. When accessed, the shortened URL may cause the stamp generation node to verify the access parameters on the blockchain and grant or deny access to the document based on the verification.

Abstract: A digital document protection system is disclosed. The system includes a processor of a stamp generation node connected to at least first user node and to a second user node over a blockchain network; a memory on which are stored machine-readable instructions that when executed by the processor, cause the processor to: receive a digital document from the first user node designated to the second user node; execute a smart contract to: generate a URL referencing a QR code and a unique tiny URL represented by the QR code, embed the QR code onto the document, wherein the document is accessible at the URL, and provide the tiny URL to the second node.

Abstract: A method of improving the adhesion of metathesis compositions, such as ring-opening metathesis polymerization (ROMP) compositions, to a substrate is disclosed, in which an adhesion promoter is added to a polymerizable resin composition in order to improve the adhesion of the polymerizing resin to a substrate material. The addition of the adhesion promoter has been found to provide beneficial improvements in the adhesion of metathesis, especially ROMP, compositions to substrates, particularly glass surfaces, leading to improved characteristics in ROMP materials formed therefrom. The adhesion promoter generally comprises a functionalized silane compound and a peroxide compound. A ROMP composition is further disclosed comprising a cyclic olefin, a ROMP metathesis catalyst, and the adhesion promoter. Polymer products produced via metathesis (ROMP) reactions of the invention may be utilized to provide a wide range of materials and in a variety of composite applications.

Abstract: The present disclosure provides a method of treating or preventing symptoms of allergic rhinitis or chronic nasal congestion in a subject by administering to the subject an MPLA compound.

Abstract: This invention relates to compositions and methods for improving the adhesion of resin compositions to substrate materials, pre-treating substrate materials to improve the adhesion of resin compositions to the substrate materials, and/or controlling gel formation of resin compositions. More particularly, the invention relates to compositions and methods for improving the adhesion of ring opening metathesis polymerization (ROMP) compositions to substrate materials using adhesion promoters containing isocyanate groups in a resin composition. The invention also relates to methods for improving the adhesion of resin compositions to substrate materials by pre-treating substrate materials with adhesion promoters containing isocyanate groups. The invention further relates to a method of providing a gel-modified ROMP composition, in which a hydroperoxide is added to a ROMP polymerizable resin composition in order to control gel formation of the polymerizing resin.

Abstract: Disclosed are pharmaceutical compositions of monophosphoryl lipid A (MPLA) like compounds, as well as methods of preparing such pharmaceutical compositions, and method of use for such compositions in treating allergic disease.

Abstract: A method of improving the adhesion of metathesis compositions, such as ring-opening metathesis polymerization (ROMP) compositions, to a substrate is disclosed, in which an adhesion promoter is added to a polymerizable resin composition in order to improve the adhesion of the polymerizing resin to a substrate material. The addition of the adhesion promoter has been found to provide beneficial improvements in the adhesion of metathesis, especially ROMP, compositions to substrates, particularly glass surfaces, leading to improved characteristics in ROMP materials formed therefrom. The adhesion promoter generally comprises a functionalized silane compound and a peroxide compound. A ROMP composition is further disclosed comprising a cyclic olefin, a ROMP metathesis catalyst, and the adhesion promoter. Polymer products produced via metathesis (ROMP) reactions of the invention may be utilized to provide a wide range of materials and in a variety of composite applications.

Abstract: A mobile communication device-based corneal topography system includes an illumination system, a mobile communication device and a corneal topography optical housing. The illumination system is configured to generate an illumination pattern and to generate reflections of the illumination pattern off a cornea of a subject, wherein the illumination system is aligned along an axis of centers of the illumination pattern. The mobile communication device includes an image sensor to capture an image of the reflected illumination pattern. The corneal topography optical housing is coupled to the illumination system and the mobile communication device, wherein the corneal topography optical housing supports and aligns the illumination system with the image sensor of the mobile communication device. The corneal topography optical housing includes an imaging system coupled to the image sensor.

Abstract: A digital document protection system is disclosed. The system includes a processor of a stamp generation node connected to at least first user node and to a second user node over a blockchain network; a memory on which are stored machine-readable instructions that when executed by the processor, cause the processor to: receive a digital document from the first user node designated to the second user node; execute a smart contract to: generate a URL referencing a QR code and a unique tiny URL represented by the QR code, embed the QR code onto the document, wherein the document is accessible at the URL, and provide the tiny URL to the second node.

Abstract: Tamper-evident features for containers. A tamper-evident film is target printed onto a sheet material that is thermoformable. The sheet is thermoformed into a container base or lid having a desired shape, such that the tamper-evident film is positioned in a desired area. A container lid is disposed on the container base, and heat sealed to a rim or edge of the container base. The heat sealing activates an adhesive of the tamper-evident film, and when the container lid is removed or separated from the container base, a first portion of the tamper-evident film remains on the container lid and a second portion remains on the container base. The separation of the tamper-evident film provides an indication of tampering.

Abstract: A mobile communication device-based corneal topography system includes an illumination system, a mobile communication device and a corneal topography optical housing. The illumination system is configured to generate an illumination pattern and to generate reflections of the illumination pattern off a cornea of a subject, wherein the illumination system is aligned along an axis of centers of the illumination pattern. The mobile communication device includes an image sensor to capture an image of the reflected illumination pattern. The corneal topography optical housing is coupled to the illumination system and the mobile communication device, wherein the corneal topography optical housing supports and aligns the illumination system with the image sensor of the mobile communication device. The corneal topography optical housing includes an imaging system coupled to the image sensor.

Abstract: A method and system for reversibly converting water between an initial ionic strength and an increased ionic strength, using a switchable additive, is described. The disclosed method and system can be used, for example, in distillation-free removal of water from solvents, solutes, or solutions. Following extraction of a solute from a medium by dissolving it in water, the solute can then be isolated from the aqueous solution or “salted-out” by converting the water to a solution having an increased ionic strength. The solute then separates from the increased ionic strength solution as a separate phase. Once the solute is, for example, decanted off, the increased ionic strength aqueous solution can be converted back to water having its original ionic strength and reused. Switching from lower to higher ionic strength is readily achieved using low energy methods such as bubbling with CO2, CS2 or COS.

Abstract: A mobile communication device-based corneal topography system includes an illumination system, a mobile communication device and a corneal topography optical housing. The illumination system is configured to generate an illumination pattern and to generate reflections of the illumination pattern off a cornea of a subject, wherein the illumination system is aligned along an axis of centers of the illumination pattern. The mobile communication device includes an image sensor to capture an image of the reflected illumination pattern. The corneal topography optical housing is coupled to the illumination system and the mobile communication device, wherein the corneal topography optical housing supports and aligns the illumination system with the image sensor of the mobile communication device. The corneal topography optical housing includes an imaging system coupled to the image sensor.

Abstract: This invention relates to compositions and methods for improving the adhesion of resin compositions to substrate materials, pre-treating substrate materials to improve the adhesion of resin compositions to the substrate materials, and/or controlling gel formation of resin compositions. More particularly, the invention relates to compositions and methods for improving the adhesion of ring opening metathesis polymerization (ROMP) compositions to substrate materials using adhesion promoters containing isocyanate groups in a resin composition. The invention also relates to methods for improving the adhesion of resin compositions to substrate materials by pre-treating substrate materials with adhesion promoters containing isocyanate groups. The invention further relates to a method of providing a gel-modified ROMP composition, in which a hydroperoxide is added to a ROMP polymerizable resin composition in order to control gel formation of the polymerizing resin.

Abstract: Tamper-evident features for containers. A tamper-evident film is target printed onto a sheet material that is thermoformable. The sheet is thermoformed into a container base or lid having a desired shape, such that the tamper-evident film is positioned in a desired area. A container lid is disposed on the container base, and heat sealed to a rim or edge of the container base. The heat sealing activates an adhesive of the tamper-evident film, and when the container lid is removed or separated from the container base, a first portion of the tamper-evident film remains on the container lid and a second portion remains on the container base. The separation of the tamper-evident film provides an indication of tampering.

Abstract: A mobile communication device-based corneal topography system includes an illumination system, a mobile communication device and a corneal topography optical housing. The illumination system is configured to generate an illumination pattern and to generate reflections of the illumination pattern off a cornea of a subject, wherein the illumination system is aligned along an axis of centers of the illumination pattern. The mobile communication device includes an image sensor to capture an image of the reflected illumination pattern. The corneal topography optical housing is coupled to the illumination system and the mobile communication device, wherein the corneal topography optical housing supports and aligns the illumination system with the image sensor of the mobile communication device. The corneal topography optical housing includes an imaging system coupled to the image sensor.

Abstract: A skin rejuvenation resurfacing apparatus comprising an oscillating, reciprocating high speed, needle-based device and its related procedure for inducing mechanical trauma to an area of the skin to be treated.

Abstract: The present disclosure provides polypeptides that have the ability to repair DNA damage by recognizing and removing a wide variety of DNA damage and distortions in double-stranded DNA. In particular, the polypeptides have the ability to remove cyclobutane pyrimidine dimers (CPDs) and/or (6-4) photoproducts from DNA. The polypeptides include at least one heterologous targeting sequence.

Abstract: The present invention is directed to addressing one or more of the aforementioned concerns and relates to thermal insulation materials and thermal insulation material compositions and methods for thermally insulating pipelines and associated equipment, structures, and objects used in offshore drilling. The present invention is directed to articles of manufacture comprising the thermal insulation materials and/or thermal insulation material compositions of the invention. More particularly the present invention relates to the use of ring opening metathesis polymerization polymers (ROMP polymers) and/or ROMP polymer composites for thermally insulating pipelines and associated equipment, structures, and objects used in offshore oil drilling.

Abstract: The invention is a new and distinct variety of grapevine plant named ‘ARAVELLE’, which is characterized by its adaptability to the Finger Lakes grape production region of New York and similar regions; fruit suitable for production of wines; moderate resistance to downy and powdery mildews; and resistance to Botrytis bunch rot.