Abstract: A window pane includes a transmission control layer including a first glass sheet, a second glass sheet, and a liquid crystal material disposed between the first glass sheet and the second glass sheet. Each of the first glass sheet and the second glass sheet has a thickness of about 1 mm or less. A first panel is bonded to the first glass sheet of the transmission control layer. A second panel is bonded to the second glass sheet of the transmission control layer. The transmission control layer is disposed between the first panel and the second panel. The liquid crystal material is controllable to adjust a transmittance of the window pane.

Abstract: The disclosure provides synthetic (e.g. recombinant) pneumococcal saccharide comprising one or more repeat unit(s) ?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?. Also provided are conjugates comprising a ?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?, immunogenic compositions, vaccines and their use in preventing or treating infection by Streptococcus pneumoniae.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: An audio scene classifier classifies an audio input signal from an audio scene and includes a pre-processing neural network configured for pre-processing the audio input signal based on initial classification parameters to produce an initial signal classification, and a scene classifier neural network configured for processing the initial scene classification based on scene classification parameters to produce an audio scene classification output. The initial classification parameters reflect neural network training based on a first set of initial audio training data, and the scene classification parameters reflect neural network training on a second set of classification audio training data separate and different from the first set of initial audio training data. A hearing implant signal processor configured for processing the audio input signal and the audio scene classification output to generate the stimulation signals to the hearing implant for perception by the patient as sound.

Abstract: A stabilization device for stabilizing an attachment component relative to movements of a basic component which occur outside a permitted plane of movement.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A stabilization device for stabilizing an attachment component relative to movements of a basic component which occur outside a permitted plane of movement.

Abstract: An audio scene classifier classifies an audio input signal from an audio scene and includes a pre-processing neural network configured for pre-processing the audio input signal based on initial classification parameters to produce an initial signal classification, and a scene classifier neural network configured for processing the initial scene classification based on scene classification parameters to produce an audio scene classification output. The initial classification parameters reflect neural network training based on a first set of initial audio training data, and the scene classification parameters reflect neural network training on a second set of classification audio training data separate and different from the first set of initial audio training data. A hearing implant signal processor configured for processing the audio input signal and the audio scene classification output to generate the stimulation signals to the hearing implant for perception by the patient as sound.

Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.

Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.

Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.

Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.

Abstract: A method performs noise suppression in hearing aids. A step of the method involves a first audio signal being split into a plurality of essentially disjunct frequency bands. A further step of the method involves a reference band being selected from the plurality of frequency bands, which reference band has an establishable first component of a speech signal. Another step involves a correlation between the reference band and a first frequency band being ascertained. A further step involves a value that indicates a second component of a speech signal in the first frequency band being ascertained on the basis of the correlation. Another step of the method involves a noise suppression being set in the first frequency band on the basis of the ascertained value.

Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.

Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.

Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.

Abstract: A method performs noise suppression in hearing aids. A step of the method involves a first audio signal being split into a plurality of essentially disjunct frequency bands. A further step of the method involves a reference band being selected from the plurality of frequency bands, which reference band has an establishable first component of a speech signal. Another step involves a correlation between the reference band and a first frequency band being ascertained. A further step involves a value that indicates a second component of a speech signal in the first frequency band being ascertained on the basis of the correlation. Another step of the method involves a noise suppression being set in the first frequency band on the basis of the ascertained value.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an A?1-peptide-VLP-composition. More specifically, the invention provides a composition comprising a virus-like particle and at least one A?1-6 peptide bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of Alzheimer's disease and as a pharmaccine to prevent or cure Alzheimer's disease and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune, responses within the indicated context.

Abstract: The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.