Abstract: Systems and methods for detecting an analyte of interest in a sample. The system can include a first container comprising a filter portion. The filter portion can include a filter comprising a filtrand of the sample on a first side of the filter. The system can further include a second container comprising the filter portion coupled to a detection portion comprising a microstructured surface. The method can include providing the first container, coupling the filter portion to the detection portion to form the second container where the first side of the filter faces the microstructured surface, and centrifuging the second container toward the microstructured surface. The method can further include inverting the second container after centrifuging to decant the supernatant from the detection portion, such that a concentrate comprising a sediment of the sample is retained in the microstructured surface, which can be interrogated for an analyte of interest.

Abstract: A device includes a tubular substrate and a support member. The support member includes a component that is elastically deformable and elastically recoverable. The support member wraps around and adheres to an abluminal surface of the tubular substrate. The device is adapted for use in an anatomical conduit. For example, the device may be adapted for bypassing an anatomical conduit, for creating an arteriovenous shunt, or as a support structure for maintaining an opening in an anatomical conduit.

Abstract: The present invention provides antibodies that bind to the endospore of the bacterium Clostridium difficile, methods of making such antibodies, and methods of using such antibodies, including methods of detecting C. difficile endospores.

Abstract: Adaptive and integrated visualization of spatiotemporal data from large-scale simulation, is provided. A simulation is performed utilizing a simulator comprising multiple processors, generating spatiotemporal data samples from the simulation. Each data sample has spatial coordinates with a time stamp at a specific time resolution, and a tag. The data samples are assembled into data streams based on at least one of a spatial relationship and the corresponding tag. Each data stream is encoded into multiple formats, and an integrated and adaptive visualization of the data streams is displayed, wherein various data streams are simultaneously and synchronously displayed.

Abstract: Access to objects of a computing environment is managed. Access to an object of the computing environment is prohibited via one cached entity corresponding to the object, while access to the object is allowed via another cached entity. The cached entities are concurrently maintained for a period of time, but the one cached entity is in a shadow state. In one example, the cached entities are session locks and the object is a file system object.

Abstract: Techniques and mechanisms for managing a delivery of power to a resource of an input/output (I/O) interface. In an embodiment, a first link of a plurality of communication links is monitored. Of the plurality of links, a first set of resources of the I/O interface is to support communication only via the first link. One or more other resources of the I/O interface are for supporting communications of another link of the plurality of links. In another embodiment, a resource of the first set of resources is decoupled from a power supply in response to detecting a total number of active lanes of the first link, decoupling.

Abstract: Methods and devices for molecular analysis are disclosed, based on centrifugation. A centrifuge device comprises strips of centrifuge tubes and elements to create a magnetic field. The magnetic shear forces applied to beads inside a solution with biological molecules permit the performance of different analytic techniques, such as lysis and sample preparation for PCR.

Abstract: Method for detecting an analyte of interest in a sample. The method can include providing a container comprising a microstructured surface, and centrifuging the container toward the microstructured surface to form a sediment and a supernatant of the sample. Following centrifugation, the container can be inverted to decant at least a portion of the supernatant of the sample from the second portion, such that a concentrate (e.g., comprising the sediment) of the sample is retained in the microstructured surface. The concentrate can then be interrogated in the microstructured surface for the analyte of interest. In some embodiments, at least a portion of the second portion can be substantially transparent, such that the concentrate can be interrogated from the outside of the container, without requiring that the container be opened prior to interrogation.

Abstract: Embodiments of the present invention provide a system that facilitates session management between a web application and a Customer Relationship Management (CRM) system. During operation, the system receives, at a proxy, a service call intended for a CRM system. Next, the system modifies a header of the service call to include authentication credentials for the CRM system. The system then determines if an available session token for the CRM system exists at the proxy. If so, the system modifies the header of the service call to include the session token. Next, the system forwards the service call with the modified header to the CRM system. The system then receives a response to the service call, which includes the session token. Upon receiving the response, the system stores the session token at the proxy for a subsequent service call. Finally, the system forwards the response to the web application.

Abstract: A film comprising stripes alternating with strands is disclosed. In some embodiments, the strands have a core and a sheath. The core is more elastic than both the sheath and the strands. In some embodiments, the film has an elongation of at least 75 percent, the width of the strands is in a range from 100 micrometers to 750 micrometers, and a portion of each strand forms part of at least one major surface of the film. An extrusion die useful for making the film and a method for making the film using the extrusion die are also disclosed.

Abstract: A datastore for a virtual machine that can be executed on a host computer networked to a physical storage system is allocated by a server. The server generates a unique identifier to associate with the datastore, wherein the unique identifier mimics a form of identifier that is generated by the physical storage system to identify volumes of physical storage in the physical storage system that are accessible to the host computer. At least one volume of physical storage in the physical storage system having physical storage available to satisfy the request to allocate the datastore is identified and the server maintains a mapping of the unique identifier to the at least one volume of physical storage and provides the mapping to the host computer upon running the virtual machine, thereby enabling the host computer to store data for the datastore in the at least one volume of physical storage.

Abstract: An incrementally activated laminate that includes an incrementally activated fibrous web and a film having alternating first and second regions and a laminate of the film and an extensible fibrous web. The first region of the film includes a first polymeric composition, and the second regions include an elastic polymeric composition that is more elastic than the first polymeric composition. In the incrementally activated laminate, the distance between midpoints of two first regions separated by one second region is smaller than the activation pitch, and the first regions are not plastically deformed. In the extensible laminate, a tensile elongation at maximum load of the film is up to 250 percent of the tensile elongation at maximum load of the extensible fibrous web. Methods of making the laminates are also described.

Abstract: A system and method for preparing and analyzing samples. The system can include a sample preparation system and a sample detection system coupled to the sample preparation system. The sample preparation system can include a deformable self-supporting receptacle comprising a reservoir adapted to contain a liquid composition comprising a source and a diluent. The sample detection system can be positioned in fluid communication with the reservoir, and can be adapted to analyze a sample of the liquid composition for an analyte of interest. The system can further include a fluid path defined at least partially by the reservoir and the sample detection system. The method can include applying pressure to the deformable self-supporting receptacle to move a sample of the liquid composition in the fluid path to the sample detection system, and analyzing the sample for the analyte of interest with the sample detection system.

Abstract: A method of generating an area efficient power switch cell includes receiving, by a cell library design tool, a specification of a power switch circuit to be established as a power switch cell in a cell library. The cell library design tool also receives one or more attributes of the power switch cell including a height of the cell boundary and receiving, by the cell library design tool, a layout placement constraint requiring the power switch cell to be placed in a semiconductor layout so as to bridge two parallel rows of doped wells. The parallel rows of doped wells are interleaved with doped substrate and the doping of the wells is of a different type than that of the substrate. Based on the specification of the power switch circuit, the one or more attributes, and the layout placement constraint, the cell library design tool generates the power switch cell.

Abstract: A method for wireless power transmission includes establishing respective wireless communication link between a coordinating transmitter and each receiver. The method further includes measuring respective mutual impedance between a coordinating transmitter and each receiver by applying a voltage to the coordinating transmitter and configuring each receiver to measure an induced current in response to the applied voltage. The method calculates respective matching impedance for the coordinating transmitter and each receiver based on corresponding mutual impedance. The method transmits the respective matching impedance to each receiver to enable each receiver to adjust to have the respective matching impedance. The method adjusts the coordinating transmitter to have the respective matching impedance.

Abstract: Novel methods and systems for polymerase chain reaction (PCR) are disclosed. A PCR device has a bottom heater layer, a central reacting layer, and a top heater layer. The central reacting layer has a PCR reacting chamber connected with fluidics channels. Photoluminescence of a DNA solution in the PCR reactive chamber is carried out through the transparent top layers.

Abstract: A contact lens (10) for use in controlling or retarding the progression of myopia in an eye has a central optical zone (20) approximating the normal diameter of the pupil of the eye (22) that gives clear central vision at distance for the wearer. An annular peripheral optical zone 24 that is substantially outside the diameter of the pupil is formed around the central optical zone (20) with greater refractive power than that of the central zone (22) so that oblique rays entering the eye through the peripheral optical zone (24) will be brought to focus at a focal plane that is substantially on or anterior to the peripheral region of the retina. Preferably, the rear surface (16) of the lens is shaped to conform to the cornea of the eye and the front surface (18) of the lens (10) is shaped to provide—in conjunction with the rear surface (16)—the desired optical properties of the central and peripheral optical zones.

Abstract: Sets, kits or stocks of anti-myopia contact or spectacle lenses, along with methods for their use, that do not require a clinician to measure peripheral refractive error in the eyes of myopic patients. Extensive surveys have shown that lenses having peripheral powers or defocus set in accordance with central corrective power will cover almost all normal myopes not worse than ?6 D central refractive error. In one example, a kit or set of lenses (50, FIG. 15) can have multiple parts or sub-sets (52, 54) each comprising a compartmented container (56a, 56b) with lenses (58a, 58b) arranged according to increments of central corrective power (59a, 59b). The lenses (58a) of the first part (52) have four steps (60a, 61a, 62a, 64a) of peripheral power or defocus to pro vide therapeutic effect and, while the lenses (58b) of the second part (54) also have four steps (60b, 61b, 62b, 64b), the level of therapeutic effect is higher.

Abstract: Methods and apparatus of allocating antennas for cyclic delay diversity (CDD) transmission are disclosed. One method includes estimating a transmission channel of a transceiver having a plurality of antennas. A subset of a plurality of transceiver antennas is selected based on the estimated transmission channel. A single transceiver antenna of the subset is identified based on a channel quality of a transmission path of the single transceiver antenna. Cyclic delay diversity (CDD) signals are transmitted from the subset of the plurality of antennas, wherein a minimally delayed CDD signal is transmitted from the identified single transceiver antenna of the subset of the plurality of transceiver antennas.

Abstract: Methods and devices for phase shifting an RF signal for a base station antenna are provided. The device includes a transmission line that has a stationary ground plane coupled to the top of a substrate and a signal line on the bottom of the substrate. The signal line has an input port and an output port. The input port receives the RF signal with a certain phase and travels across the bottom of the substrate to the output port. The RF signal has a different phase at the output port because defected ground structures etched on the stationary ground plane shift the phase of the RF signal. In addition, the device includes a movable ground plane that may cover a portion of the defected ground structures, the substrate, and the stationary ground plane such that the moveable ground plane further adjusts the phase of the RF signal.