Abstract: Described is a technology in which a set of objects represent educational entities of an educational model, with relationships between objects. For example, a course object instance may have a relationship with a task instance and a user instance (such as representing a student). Other objects may include user credentials objects, group objects, degree program objects, course plan objects, institution objects, school objects, and/or department objects. The set of objects may be pre-defined and maintained in a persistent storage; this pre-defined set may be extended with an extended object that has relationships with pre-defined objects. The educational entities of an object model may be maintained in rows of a table, with each row having a field that identifies which entity is represented by that row. The table is accessed to determine relationships between an instantiated object for an entity and at least one other instantiated object for another entity.

Abstract: A binary rewriter that can provide complete code coverage without relocation information is provided, together with a method of performing such rewriting. The method can include processing a binary file as an original binary file. The method can also include disassembling the binary file to provide a disassembled binary file. The method can further include rewriting the disassembled binary file without relocation information to provide a rewritten binary file. The rewriting can provide a physical transformation in a recording medium relative to the binary file in the recording medium prior to the rewriting. The processing the binary file, disassembling the binary file, and rewriting the disassembled binary file can be performed by a particular machine.

Abstract: Binary rewriters that do not require relocation information and automatic parallelizers within binary rewriters are provided, as well as methods for performing binary rewriting and automatic parallelization. The method, in certain embodiments. includes disassembling a binary file and determining functions in the disassembled binary file. The method can further include rewriting the binary file without relying on relocation information or object files. Optionally, the method can further include performing automatic parallelization of the binary before rewriting the binary file.

Abstract: This invention relates to a simple end point assay for detection of transient intracellular Ca2+ with broad applicability to many Ca2+channel proteins comprising, Generation of expression constructs for the fusion proteins having the Ca2+/calmodulin dependent protein kinase II (CaMKII) phosphorylation sites of NR2A or NR2B subunits of N-methyl-D-aspartate receptor (NMDAR) or the voltage gated potassium channel of Drosophila (Eag) or any protein sequence which binds to the T-site of CaMKII similar to NR2B, conjugated to mitochondrial localizing signal sequence, or mutants of these sequences as described herein. Generation of mammalian expression constructs of ?-CaMKll as a chimera with green fluorescent protein (GFP-?-CaMKII) or its mutants as described herein.

Abstract: Provided is a process for the preparation of flame retardant cellulosic product including the steps of adding a soluble salt of silica to viscose, followed by blending and extruding the blended viscose into a spin bath, regenerating the viscose and subjecting the regenerated viscose to a step of glow proofing with polyaluminium compounds to obtain the flame retardant cellulosic product.

Abstract: The attached disclosure provides a systems approach based on mathematical modelling of the kinetics of essential biochemical pathways involved in organ homeostasis. When this in silico model is coupled with in-vitro and/or in-vivo measurements to quantify drug-induced perturbations, a powerful platform that allows accurate and mechanistic-level prediction of drug-induced organ injury can be generated. The method described in this disclosure demonstrates that several physiological situations can also be accurately modelled in addition to the effect of perturbations induced by drugs. It can also be used along with high-throughput “omics” data to generate testable hypotheses leading to informed decision-making in drug development.

Abstract: In one embodiment, an optimization hint may be included in a business process flow. An executable process may be generated from the business process flow where the optimization hint is included in the executable process. While executing the executable process, the runtime engine encounters an optimization hint and determines an optimization to perform. The optimization hint may be related to an aspect of a business process being orchestrated by the business process flow. The optimization is then performed while executing the executable process. For example, the runtime engine may start pre-processing the branch while the condition is being evaluated. If the condition evaluates such that the pre-processed branch should be executed, then the runtime engine has already started processing of that branch. The processing is thus optimized in that the runtime engine is not sitting idle while waiting for the condition to be evaluated.

Abstract: A flame retardant and glow resistant zinc free cellulose product containing silica, modified with polyaluminium ions. In the preparation of product the cellulose solution (viscose) and sodium silicate are blended and regenerated to obtain a polymeric silica in the cellulose structure which is further modified with polyaluminium ions to attach aluminium sites on silica molecules to make the product glow resistant and impart wash fastness as well.

Abstract: Provided is a process for the preparation of flame retardant cellulosic product including the steps of adding a soluble salt of silica to viscose, followed by blending and extruding the blended viscose into a spin bath, regenerating the viscose and subjecting the regenerated viscose to a step of glow proofing with polyaluminium compounds to obtain the flame retardant cellulosic product.

Abstract: A linkage control system for a machine having a linkage and a work implement is disclosed. The linkage control system has an operator input device configured to control the movement of the linkage, at least one actuator configured to respond to the operator input device to control the movement of the linkage, and at least one sensor configured to generate a signal indicative of sensor data on at least one actuator. The linkage control system has a controller in communication with at least one actuator, at least one sensor, and the operator input device. The controller is configured to calculate the position of the linkage, to detect anomalous sensor data from at least one sensor, and to predict the position of the linkage and work implement based on a last known accurate position, a last known accurate sensor data, and the operator input device.

Abstract: In mammalian systems, RNA interference (RNAi)-based suppression of target gene expression may be activated by delivery of RNAi probes such as double stranded small interfering RNA (siRNA) molecules or short hairpin RNAs (shRNAs), where the RNAi probe sequence is homologous to the target-gene. A reliable and quantitative method is provided for the rapid and efficient identification of RNAi probes that are most effective in providing RNAi-mediated suppression of target gene expression. This method may be used for high-throughput screens to identify effective RNAi probes.

Abstract: A system for transferring data includes an interface configured to receive data that is sent via a first link, and a processor coupled to the interface. The processor is configured to: receive data that is sent via a first link; determine whether there is discontinuity in the received data, the determination being based at least in part on information included in the received data; in the event that the received data includes a discontinuity, generate replacement data that repairs the discontinuity; and transmit at least a portion of replacement data to a second link such that a synchronization requirement associated with the second link is fulfilled.

Abstract: A merchant scoring system predicts and reports the likelihood that a merchant is reliable (e.g., trustworthy, honest, and reputable), which is expected to translate into a positive consumer experience. The system collects data from a variety of data sources, including combinations of the merchant, third-parties, and/or customers who have transacted with the merchant. A scoring model is executed on this collected data to determine an independent and objective merchant reliability metric that predicts the expected reliability of a merchant within a range. The system may also track transactions of individual merchants, populating a transaction history database with information about each merchant for use in this collection and scoring process. The transaction history data and other data may also be accessible to a prospective customer to build his or her confidence in and understanding of the merchant reliability metric and his or her trust of the merchant.

Abstract: A system, process and methods for providing a mobile to mobile service invocation framework in which a mobile device can invoke a service or request a data from another mobile or non-mobile device. The request from a mobile device is sent as a text message to another mobile device's phone number or as an email to another mobile device or non-mobile device. The request contains, among other things, a command and required data to enable the framework running on the destination device to execute the request and return the result as a text message back to the caller device. The framework also breaks the text message into pieces of max allowed size before sending, and, the pieces are rejoined by the framework at receiving end before executing a service.

Abstract: A highly predictable, low overhead and yet dynamic, memory allocation methodology for embedded systems with scratch-pad memory is presented. The dynamic memory allocation methodology for global and stack data (i) accounts for changing program requirements at runtime; (ii) has no software-caching tags; (iii) requires no run-time checks; (iv) has extremely low overheads; and (v) yields 100% predictable memory access times. The methodology provides that for data that is about to be accessed frequently is copied into the SRAM using compiler-inserted code at fixed and infrequent points in the program. Earlier data is evicted if necessary.

Abstract: In a finite state machine (FSMverify) a set of goal states, to be searched for their reachability from a start state, is defined. An overapproximated path is found from a start state to a goal state by a forward approximation technique. The overapproximated path representation relies upon a partitioning of the state and input bits of FSMverify. A state matrix of the overapproximated path is organized by time-steps of FSMverify along a first dimension and by partitions of FSMverify state bits along a second dimension. An underapproximated path, along the path of the stepping stone matrix, is determined. Underapproximation is typically accomplished by simulation. A sequence of states to be output is updated with the underapproximated path. If a start to goal state sequence has been found, the procedure ends. Otherwise, the above steps of over and under approximation are repeated, using the results of the last underapproximation as a start state.

Abstract: In mammalian systems, RNA interference (RNAi)-based suppression of target gene expression may be activated by delivery of RNAi probes such as double stranded small interfering RNA (siRNA) molecules or short hairpin RNAs (shRNAs), where the RNAi probe sequence is homologous to the target gene. A reliable and quantitative method is provided for the rapid and efficient identification of RNAi probes that are most effective in providing RNAi-mediated suppression of target gene expression. This method may be used for high-throughput screens to identify effective RNAi probes.

Abstract: Hair growth can be reduced by topical application of a composition including an emulsion and a compound that inhibits hair growth. The emulsion (1) is prepared using a phase inversion procedure, (2) includes droplets having an average size of from 10 nm to 150 nm, (3) includes droplets sufficiently small that the composition is clear, (4) is in the form of a nanoemulsion, and/or (5) is an oil-in-water emulsion in which the compound that inhibits hair growth is dissolved in the water phase and the oil phase includes glyceryl isostearate.

Abstract: A method and apparatus are provided that facilitate analysis of the intended flow of logical signals between key points in a design. According to one aspect of the present invention, a comprehensive set of design verification checks may be formulated by applying predetermined properties to an annotated hardware design representation. Information regarding the intended flow of logical signals in the hardware design is received by way of annotations in a control file or annotations embedded in the hardware design representation itself. The annotations include (1) an indication of one or more variables in the representation of the hardware design through which the logical signals pass, and (2) an indication of one or more conditions under which each of the one or more variables are to be associated with each of a set of states. Checks are then automatically formulated based upon a predetermined set of properties that must hold true in order for the hardware design to operate in accordance with the intended flow.