Abstract: Methods and reagents are provided for determining endocytosis, using a cell expressing an externally polypeptide labeled cell membrane receptor, and as a reagent an antibody to said label conjugated to a fragment of an enzyme fragment complementation pair. Compounds are tested for their effect on endocytosis by complexing the reagent with said cells, adding the test compound at any time in relation to the complexing, allowing any endocytosis to occur, proteolytically degrading external enzyme fragment, adding protease inhibitor and the complementary member of the enzyme fragment complementation pair and substrate. The product provides a detectable signal related to the amount of endocytosis that occurred. The method is readily automated as all steps can occur in a single vessel without separations and washings.

Abstract: The present invention is directed to a tubular article of manufacture in an annular or tubular shape having an outer diameter, an inner diameter and a length comprising one or more materials selected from the group consisting of: a) an immiscible blend of polymers comprising one or more polyetherimides, having more than one glass transition temperature wherein the polyetherimide has a glass transition temperature greater than 217° Celsius; b) a miscible blend of polymers, comprising one or more polyetherimides, having a single glass transition temperature greater than 180° Celsius; or, c) a single polyetherimide having a glass transition temperature of greater than 247° Celsius.

Abstract: Blends of polysulfones, polyethersulfones and polyphenylene ether sulfones with resorcinol based polyesters, or resorcinol based polyester carbonate polymers, and silicone copolymers have improved flame resistance. Peak heat release energy is reduced and the time to reach peak heat release is increased.

Abstract: The present invention is directed to a tubular article of manufacture in an annular or tubular shape having an outer diameter, an inner diameter and a length comprising one or more materials selected from the group consisting of: a) an immiscible blend of polymers comprising one or more polyetherimides, having more than one glass transition temperature wherein the polyetherimide has a glass transition temperature greater than 217° Celsius; b) a miscible blend of polymers, comprising one or more polyetherimides, having a single glass transition temperature greater than 180° Celsius; or, c) a single polyetherimide having a glass transition temperature of greater than 247° Celsius

Abstract: A composite material comprises an electrically conductive material disposed over at least a portion of a substrate wherein the substrate comprises either: a) an immiscible blend of polymers having more than one glass transition temperature and one of the polymers has a glass transition temperature greater than 180 degrees Celsius; b) a miscible blend of polymers having a single glass transition temperature greater than 217 degrees Celsius; or, c) a single virgin polymer having a glass transition temperature of greater than 247 degrees Celsius.

Abstract: Blends of polyimides, polyetherimides or polyetherimide sulfones with resorcinol based polyesters, or resorcinol based polyester carbonate polymers, and silicone copolymers, have improved flame resistance. Peak heat release energy is reduced and the time to reach peak heat release is increased. In some instances the flame retardant blends show high percent transmission with low haze. Addition of metal oxides may further improve flame resistance.

Abstract: The present invention relates generally to the field of articles of manufacture in the form of a shaped article comprising a blend of polymers wherein all, or some of, one or more surfaces of the shaped article is coated with a covering material, wherein the covering material has a different composition than the shaped article, and, wherein the shaped article comprises either: a) an immiscible blend of polymers having more than one glass transition temperature and one of the polymers has a glass transition temperature greater than 180° Celsius; b) a miscible blend of polymers having a single glass transition temperature greater than 217° Celsius; or, c) a single virgin polymer having a glass transition temperature of greater than 247° Celsius. The present invention is also directed to light source reflectors comprising a polymer according to a), b) or c) above.

Abstract: A cellular communications system comprising a space based system comprising a first set of cells, and a ground based system comprising a second set of cells The space and ground systems can optionally function substantially autonomously, with each using spectrum from at least one predetermined frequency band.

Abstract: A method of communicating data between a first transceiver and any of a plurality of second transceivers, wherein areas serviced by each of the plurality of second transceivers either overlap or are adjacent. The method comprises operating the first transceiver and the plurality of second transceivers in an overlapping frequency range. Each of the plurality of second transceivers operates in a time period different from a time period of another of the plurality of second transceivers.

Abstract: An amplifiable ?-lactamase substrate is provided comprising an enzyme donor fragment of ?-galactosidase linked to form a ring to a ?-lactam ring that is a substrate for lactamase and upon opening of the ?-lactam ring the enzyme donor fragment becomes linearized. The cyclic substrate only weakly binds to the enzyme acceptor fragment of ?-galactosidase. The substrate finds application for the sensitive detection of ?-lactamase for direct detection of the enzyme or when the enzyme is used as a label.

Abstract: A system and method of operation for efficiently reusing and/or sharing at least a portion of the frequency spectrum between a first satellite spot beam and a second satellite spot beam, and/or an underlay terrestrial network associated with a second satellite spot beam. The spectrum is efficiently reused and/or shared between respective spot beams and/or associated underlay terrestrial systems in a manner minimizes interference between the respective satellite and terrestrial systems.

Abstract: Short enzyme donor fragments of ?-galactosidase are provided of not more than 40 amino acids, where the short fragments are used as a label and may be substituted with a wide variety of organic compounds, particularly polypeptides having independent functional activity. The enzyme donor finds use in competitive and non-competitive assays, monitoring intracellular events, or other processes where a sensitive non-interfering label is desired.

Abstract: A system and method of operation for efficiently reusing and/or sharing at least a portion of the frequency spectrum between a first satellite spot beam and a second satellite spot beam, and/or an underlay terrestrial network associated with a second satellite spot beam. The spectrum is efficiently reused and/or shared between respective spot beams and/or associated underlay terrestrial systems in a manner minimizes interference between the respective satellite and terrestrial systems.

Abstract: Methods and compositions are provided for determining ADP in the presence of ATP. These comprise including among the assay reagents at least one of the correcting components creatine phosphokinase and phosphocreatine, pyruvate kinase and phosphoenolpyruvate, peroxidase and a non-interfering peroxidase substrate, and catalase. One aspect of the method employs formation of hydrogen peroxide from the ADP by pyruvate kinase, phosphoenolpyruvate and pyruvate oxidase. The hydrogen peroxide is then determined. A combined reagent having all of the reagents may optionally include a peroxidase when the hydrogen peroxide is to be enzymatically determined. A peroxidase substrate is added to the sample in conjunction with the peroxidase substrate reagent, the mixture incubated and depending on whether the peroxidase substrate is a fluorescer or chemiluminescer, the mixture may be illuminated with excitation light and the emitted light determined as a measure of the ADP in the sample.

Abstract: A system and method of operation for efficiently reusing and/or sharing at least a portion of the frequency spectrum between a first satellite spot beam and a second satellite spot beam, and/or an underlay terrestrial network associated with a second satellite spot beam. The spectrum is efficiently reused and/or shared between respective spot beams and/or associated underlay terrestrial systems in a manner minimizes interference between the respective satellite and terrestrial systems.

Abstract: A method for planning the establishment of a business comprising the steps of providing partner characteristic information representing objective representations of characteristics of potential partners, providing location characteristic information representing objective representations of characteristics of potential business locations providing a minimum profit desired for the operation of said business, determining constraints for optimizing potential partners and potential locations to be used for determining profits according to a selected partner and selected locations; and determining a set of results wherein each member of said set of results contains at least one potential partner and at least one potential location according to said constraints.

Abstract: A thermoplastic composition comprises greater than or equal to about 60 wt. % polycarbonate; and about 10 wt. % to about 40 wt. % of a polyimide; wherein weight percents are based on a total weight of the thermoplastic composition.

Abstract: Methods and reagents are provided for determining endocytosis, using a cell expressing an externally polypeptide labeled cell membrane receptor, and as a reagent an antibody to said label conjugated to a fragment of an enzyme fragment complementation pair. Compounds are tested for their effect on endocytosis by complexing the reagent with said cells, adding the test compound at any time in relation to the complexing, allowing any endocytosis to occur, proteolytically degrading external enzyme fragment, adding protease inhibitor and the complementary member of the enzyme fragment complementation pair and substrate. The product provides a detectable signal related to the amount of endocytosis that occurred. The method is readily automated as all steps can occur in a single vessel without separations and washings.

Abstract: Selected data packets that were broadcast over millimeter microwave frequencies to millimeter microwave receiving stations in a millimeter microwave broadcasting system footprint are rebroadcast. Rebroadcasting is selected based upon an indication that is received from a subset of the millimeter microwave receiving stations, that the one or more data packets were not received successfully by the subset of the millimeter microwave receiving stations. Selective rebroadcasting may be performed based upon statistical analysis of indications that are received from the subset of the millimeter microwave receiving stations.

Abstract: The present invention relates generally to novel protein modification reagents for fractionation and quantitative (differential) profiling of proteins in a complex mixture. The reagents react with amino acids or other protein components or structures and function as mass tags. The present invention provides methods of making the protein modification reagents and methods of using the protein modification reagents for quantitative analysis of proteins.