Abstract: Compositions and methods are provided for preparing nanosized biologically nucleic acids, including agents formulated for target specific drug delivery. In some embodiments, the nanoparticles comprise a polymer coating, which can provide for controlled delivery, targeting, controlled release, and the like. In other embodiments, the nanoparticles comprise a target specific tag for targeting the nanoparticles to a site of interest, e.g. tissue, cell, etc.

Abstract: The inventive system and method for improving network security, availability, and regulatory compliance, and maximizing a network comprises a network configuration component, a network inventory component, a network monitoring component, and a network assessment component, wherein information is extracted from each of the configuration, inventory, and monitoring components, the extracted information is combined and assessed in the assessment component, and the maximized network is produced using the combined information. In one embodiment, the combined information is stored in a database. In one embodiment, an XML is produced from the extracted inventory information, and this XML is converted to a canonical form.

Abstract: An automated method for checking electrostatic discharge (ESD) guidelines ensures that a sufficient number of ESD protection cells have been provided in the neighborhood of each pad in an integrated circuit design to ensure adequate current sinking and voltage clamping during the occurrence of an ESD event.

Abstract: Provided is a method that enables an interpretive engine to execute in a non-homogeneous, multiple processor architecture. Am interpretive engine is modified to identify code native to a target processor that is executing an ISA different than the ISA of the processor executing the interpretive engine. An intermediate function is called to correlate the native code with a processor type and a target processor is identified. A context is created for the native code and the context is either transmitted to the target processor or stored in a memory location such that the target processor may retrieve the context. Once the context is transmitted, the target processor executes the task. Results are either transmitted to the originating processor or placed in memory such that the originating processor can access the result and the originating processor is signaled of the completion of the task.

Abstract: A slatwall mounting system includes a rail member and a mounting arrangement. The rail member includes longitudinally extending upper and lower edges, a longitudinally extending upper slot portion including a downward extending undercut a longitudinally extending lower slot portion including an upward extending undercut. The mounting arrangement includes a bracket member having a downward oriented hook portion and a mounting aperture, and a cam assembly having a mounting cam assembled with a user graspable cam driver, the cam and cam driver defining an annular groove for securing the cam assembly to the mounting aperture. The mounting cam is rotatable between a slatwall securing position for mounting engagement with the lower slot of the rail member, and a slatwall releasing position, in response to user manipulation of the cam driver.

Abstract: Systems and methods for the dissemination of information from a controlled environment facility employ facility information management functionality managing resident information and facility information, and call manager functionality selectively providing at least a portion of the resident information and/or the facility information to an outside party in an automated manner. The invention may employ outgoing IVR functionality to provide select portions of the resident information in response to the call manager recognizing that a call is a first call by a resident, or a first call to a particular telephone number by a resident. The invention may manage information related to providers of services or goods for residents of a facility, provide an outside party this information, and notify a selected provider of selection of that provider by the outside party to provide goods or services for a resident.

Abstract: An Algorithmic Reactive Testbench (ART) system is provided. The ART system is a high level verification environment with a user program in which on or more analog testbenches are instantiated and operated as prescribed in the program algorithm, and the properties of the unit testbenches (test objects) can be influenced by prior analysis of themselves or other tests. The results of the analysis may also affect the flow of the program itself. In the ART system, modification of the properties of a unit testbench occurs separately in the user program after definition of the unit testbench in the program (test object). A test object is a representation of a unit testbench along with its complete simulation setup and all associated data for the simulation. The test object may also contain various properties including information reflecting the status of the test object. The modification of a property of a test object is an act of communication in the ART system from the ART program to the test object.

Abstract: The present invention relates to compounds of formula (I): wherein Q, G1, G2, and G3, are defined herein. Pharmaceutical compositions and methods for treating DGAT-1 related diseases or conditions are also disclosed.

Abstract: Compounds of formula (I), or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof, Pharmaceutical compositions of formula (I) and related methods for treating or preventing metabolic diseases or conditions.

Abstract: A method is provided for identifying and isolating peptides capable of binding of inorganic materials such as silica, silver, germanium, cobalt, iron, or oxides thereof, or other materials on a nanometric scale such as carbon nanotubes, using a combinatorial phage display peptide library and a polymerase-chain reaction (PCR) step to obtain specific amino acids sequences. In the method of the invention, a combinatorial phage display library is used to isolate and select the desired binding peptides by a series of steps of target binding of phage with the nanometric material of interest, elution and purification of the bound phages, and amplification using PCR to determine the sequences of phages producing the desired binding peptides. The binding peptides of the invention are particularly advantageous in that they may be used as templates to guide the development of useful structures on a nanometric scale.

Abstract: A family of reflectin proteins is identified herein that is deposited in flat, structural platelets in reflective tissues of the squid Euprymna scolopes. These proteins are encoded by at least six genes in three subfamilies and have no reported homologues outside of squids. Reflectins possess 5 repeating domains, that are remarkably conserved among members of the family. The proteins have a highly unusual composition with four relatively rare residues (tyrosine, methionine, arginine, and tryptophan) comprising ˜57% of a reflectin, and several common residues (alanine, isoleucine, leucine, and lysine) occurring in none of the family members. These protein-based reflectors in squids provide a striking example of nanofabrication in animal systems.

Abstract: In accordance with embodiments of the present invention a present authentication or identification process includes iterative and successive cross-hatching of biometric components such as voice print, fingerprint, hand analysis, retina scan, iris scan, and/or features (such as facial characteristics, scars, tattoos and/or birthmarks) with other identifying data such as a PIN, password phrase, barcode, or identification card.

Abstract: A wavelength router to be used for fiber optical networking router is based on a diffraction grating which utilizes only N wavelengths to interconnect N inputs to N outputs. The basic approach is to augment the grating with additional couplers or wavelength selective elements so than N?1 of the 2N?1 outputs are combined with other N outputs (leaving only N outputs). One embodiment uses directional couplers as combiners. Another embodiment uses wavelength-selective couplers. Another embodiment uses a pair of diffraction gratings to maintain parallel propagation of all optical beams. Also, beam combining can be implemented either by using retroflection back through the grating pair or by using couplers.

Abstract: A mechanism is provided at a host system to allow multiple entities (clients) to send and receive messages of a particular class of management services in a switched fabric for scalable solutions.

Abstract: An apparatus and method for detecting infrared radiation is provided which comprises a temperature-sensing helical coiled-coil protein such as TlpA, CC1, collagen or myosin, incorporated into an electrically conductive film or gel deposited onto an electrically conductive medium such as an electrode, means for recording changes in conductivity or resistance of the conductive film or gel caused by the presence of infrared radiation and the effect of the infrared radiation on the thermal-sensing protein, and means to analyze the changes in conductivity or resistance in the conductive film caused by the infrared radiation so as to determine if infrared radiation is present.

Abstract: The present invention relates to compounds that activate AMP-activated protein kinase (AMPK), including the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders such as diabetes, metabolic syndrome, and obesity.

Abstract: A host is coupled to a cluster interconnection fabric which includes a fabric-attached I/O controller. The host includes a processor, a memory coupled to the processor and an operating system. The operating system includes a kernel and a fabric bus driver to provide an I/O bus abstraction to the kernel for the cluster interconnection fabric. The fabric bus driver presents the cluster interconnection fabric to the kernel as a local I/O bus, and presents the fabric-attached I/O controller to the kernel as a local I/O controller attached to a local I/O bus.

Abstract: A cluster having a host connected thereto via a cluster interconnection fabric where a determination is made as to whether an error condition exists in an I/O controller connected to the host via the cluster interconnection fabric. This is achieved by attempting to communicate with the I/O controller a first predetermined time period after an inquiry by an operating system as to whether or not an I/O controller driver stack should be unloaded. Also, the operating system is commanded to unload the I/O controller driver stack upon a determination that the error condition still exists.

Abstract: A host is coupled to a cluster fabric which includes a fabric-attached I/O controller. The host includes a processor, a memory coupled to the processor and an operating system. The operating system includes a kernel and a fabric bus driver to provide an I/O bus abstraction to the kernel for the cluster fabric to report multiple paths to a target fabric-attached I/O controller.

Abstract: A parent driver desiring to access a service of a child driver in a driver stack creates a virtual device object. The virtual device object is inserted into the driver stack below the child driver. When a query to dynamically remove the driver stack arrives at the virtual device object, the virtual device object notifies the parent driver. The parent driver stops accessing the child driver before directly receiving and processing the remove query, allowing the driver stack to be removed after all drivers in the driver stack process the remove query.