Patents by Inventor Rajesh Singh

Rajesh Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240350489
    Abstract: The invention concerns method of treating multiple sclerosis (MS) by administering a therapeutically effective dose of LOU064 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 1, 2022
    Publication date: October 24, 2024
    Inventors: Souvik BHATTACHARYA, Bruno BIETH, Bruno CENNI, Peter END, Gordon GRAHAM, Michael JUHNKE, Rajesh Singh KARAN, Allison Donna MANN, Etienne PIGEOLET, Karin RAPP, Kim-Hien SIN, Huixin YU, Ying ZHANG
  • Patent number: 12116411
    Abstract: The invention relates to new anti-hCD3 antibodies that, in contrast to prior art anti-CD3 antibodies, bind specifically to human CD3 at acidic pH, but do not significantly bind to human CD3 at neutral or physiological pH, methods to produce these antibodies and therapeutic uses of these antibodies. These antibodies are able to activate T cells at acidic pH while having significantly reduced activity at neutral or physiological pH.
    Type: Grant
    Filed: November 2, 2021
    Date of Patent: October 15, 2024
    Assignee: Abzyme Therapeutics LLC
    Inventors: Hiep Tran, Carla Campbell, Byung Lee, Fouad Moussa, Andrew Phillips, Rajesh Singh, Laura DeCristofano
  • Patent number: 12033493
    Abstract: In some embodiments, methods and systems are provided for managing emergency notifications and incident reports at a commercial facility. A graphical interface enables a worker associated with a facility to input information regarding an ongoing/impending emergency event, e.g., Active Threat, Acts of Violence, Fire/Explosion, Injury, Power Failure, Missing Child, Severe Weather, Robbery, Hazmat, Bomb Threat, Covid-19, Store Closure, Special Events etc. This information is processed via an analytical engine that evaluates the entered information in view of various business rules in order to identify the appropriate workers to notify, and generates and transmits the notifications to the employees determined to be suitable for receiving a notification. In response to the generation of the emergency notification, an incident report engine evaluates the entered emergency, and automatically generates an incident report, which may be later accessed and/or modified by workers having a suitable employee access level.
    Type: Grant
    Filed: May 9, 2023
    Date of Patent: July 9, 2024
    Assignee: Walmart Apollo, LLC
    Inventors: Tanvi Chopra, Grace K. Shea, Sharon Grayce Randolph, David M. Nelms, Rajesh Singh, Kartik S. Soni
  • Publication number: 20230282095
    Abstract: In some embodiments, methods and systems are provided for managing emergency notifications and incident reports at a commercial facility. A graphical interface enables a worker associated with a facility to input information regarding an ongoing/impending emergency event, e.g., Active Threat, Acts of Violence, Fire/Explosion, Injury, Power Failure, Missing Child, Severe Weather, Robbery, Hazmat, Bomb Threat, Covid-19, Store Closure, Special Events etc. This information is processed via an analytical engine that evaluates the entered information in view of various business rules in order to identify the appropriate workers to notify, and generates and transmits the notifications to the employees determined to be suitable for receiving a notification. In response to the generation of the emergency notification, an incident report engine evaluates the entered emergency, and automatically generates an incident report, which may be later accessed and/or modified by workers having a suitable employee access level.
    Type: Application
    Filed: May 9, 2023
    Publication date: September 7, 2023
    Inventors: Tanvi Chopra, Grace K. Shea, Sharon Grayce Randolph, David M. Nelms, Rajesh Singh, Kartik S. Soni
  • Publication number: 20220329084
    Abstract: The present invention generally relates to a self-charging system for electric vehicles comprises at least one gearbox comprises an input end and an output end mechanically coupled to one of the wheels of a vehicle to the input end to generate a rotational energy with an increased output of one of the torque or speed (RPM) to the output end; an auxiliary generator connected to the output end of the at least one gearbox to convert the rotational energy into electrical energy; a controller equipped with a maximum power point tracker to produce maximum power output; and a charger controller coupled to the maximum power point tracker to charge a batter of the vehicle upon limiting electric current rate of the power output to protect against electrical overload, overcharging, and overvoltage.
    Type: Application
    Filed: June 28, 2022
    Publication date: October 13, 2022
    Inventors: Vineet Tirth, Anush Prabhakaran, Ram Karan Singh, Puneet Kumar Gupta, Santosh Kumar Singh, Rakesh Ranjan, Rajesh Singh
  • Publication number: 20220135680
    Abstract: The invention relates to new anti-hCD3 antibodies that, in contrast to prior art anti-CD3 antibodies, bind specifically to human CD3 at acidic pH, but do not significantly bind to human CD3 at neutral or physiological pH, methods to produce these antibodies and therapeutic uses of these antibodies. These antibodies are able to activate T cells at acidic pH while having significantly reduced activity at neutral or physiological pH.
    Type: Application
    Filed: November 2, 2021
    Publication date: May 5, 2022
    Inventors: Hiep Tran, Carla Campbell, Byung Lee, Fouad Moussa, Andrew Phillips, Rajesh Singh, Laura DeCristofano
  • Publication number: 20200209248
    Abstract: Methods for diagnosing cancer in a subject are disclosed. The method includes detecting the level of expression of one or more cancer markers in a biological sample obtained from the subject; and comparing the level of expression of the one or more cancer markers in the biological sample to a normal level of expression of the one or more cancer markers. The one or more cancer markers comprises CXCL13 or CXCR5 or both CXCL13 and CXCR5. Also disclosed is a kit for detecting cancer or monitoring cancer progression.
    Type: Application
    Filed: August 12, 2019
    Publication date: July 2, 2020
    Inventors: James W. Lillard, Rajesh Singh, Shailesh Singh
  • Patent number: 10614096
    Abstract: A method for copying first data stored at a primary data center to a secondary data center is provided. The method includes initiating a first replication task to copy the first data from the primary data center to the secondary data center. The method also includes receiving a first portion of the first data from the primary data center via a first access point, wherein a first bandwidth between the primary data center and the first access point is greater than a second bandwidth between the primary data center and the secondary data center. The method further includes storing the first portion of data in a first cache associated with the first access point. The method also includes transmitting the first portion of data from the first cache to the secondary data center. A system and non-transitory computer-readable medium are also provided.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: April 7, 2020
    Assignee: VMware, Inc.
    Inventor: Rajesh Singh
  • Patent number: 10346774
    Abstract: This disclosure generally relates to devices, systems, and computer-implemented methods for simulating one or more inventories in a distribution network. Specifically, methods are described that comprise the operations of receiving inventory data for one or more inventories to be simulated, wherein the inventory data includes lead time data and demand data; determining, based on the inventory data, probability distributions for each of lead time and demand for the one or more inventories to be simulated; determining a lead time demand probability distribution of the one or more inventories to be simulated based on the determined probability distributions for the lead time and the demand; determining a predictive state of the one or more inventories to be simulated based on the lead time demand probability distribution; and outputting one or more evaluation parameters associated with the predictive state of the one or more inventories to be simulated.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: July 9, 2019
    Assignee: Accenture Global Services Limited
    Inventors: Yair Martinez, Javier Subira Escrig, Dario Romare, Jaime Lagunas, Robert Gimeno, Ghanshyam Devnani, Rajesh Singh
  • Publication number: 20180343854
    Abstract: The present application relates to a nanoparticle compositions and methods for targeted delivery of a bioactive agent to a plant. In one embodiment, the nanoparticle composition includes a coronatine-coated nanoparticle formulated to deliver one or more bioactive agent through plant stomata. A variety of bioactive agents may be included in the nanoparticles, including one or more bactericides, fungicides, insecticides, acaricides, miticides, nemanticides, molluscicides, herbicides, plant nutrients, fertilizers, plant growth regulators, or combinations thereof.
    Type: Application
    Filed: July 26, 2018
    Publication date: December 6, 2018
    Inventors: James W. Lillard, JR., Rajesh Singh
  • Patent number: 10058093
    Abstract: The present application relates to a nanoparticle compositions and methods for targeted delivery of a bioactive agent to a plant. In one embodiment, the nanoparticle composition includes a coronatine-coated nanoparticle formulated to deliver one or more bioactive agent through plant stomata. A variety of bioactive agents may be included in the nanoparticles, including one or more bactericides, fungicides, insecticides, acaricides, miticides, nemanticides, molluscicides, herbicides, plant nutrients, fertilizers, plant growth regulators, or combinations thereof.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: August 28, 2018
    Assignee: JYANT TECHNOLOGIES, INC.
    Inventors: James W. Lillard, Jr., Rajesh Singh
  • Publication number: 20180232429
    Abstract: A method for copying first data stored at a primary data center to a secondary data center is provided. The method includes initiating a first replication task to copy the first data from the primary data center to the secondary data center. The method also includes receiving a first portion of the first data from the primary data center via a first access point, wherein a first bandwidth between the primary data center and the first access point is greater than a second bandwidth between the primary data center and the secondary data center. The method further includes storing the first portion of data in a first cache associated with the first access point. The method also includes transmitting the first portion of data from the first cache to the secondary data center. A system and non-transitory computer-readable medium are also provided.
    Type: Application
    Filed: April 17, 2018
    Publication date: August 16, 2018
    Applicant: VMware, Inc.
    Inventor: Rajesh Singh
  • Patent number: 9971658
    Abstract: A system and method for deploying clients at a target site with disaster recovery considerations uses recovery profiles with multiple recovery parameter settings, which can be associated with a client to be deployed. The recovery profile associated with the client is used to automatically initiate a recovery-related operation for the client using a recovery parameter setting defined in the recovery profile associated with the client.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: May 15, 2018
    Assignee: VMware, Inc.
    Inventors: Rajesh Singh, Girish Ramchandra Rao, Puneet Gupta
  • Patent number: 9953072
    Abstract: A method for copying first data stored at a primary data center to a secondary data center is provided. The method includes initiating a first replication task to copy the first data from the primary data center to the secondary data center. The method also includes receiving a first portion of the first data from the primary data center via a first access point, wherein a first bandwidth between the primary data center and the first access point is greater than a second bandwidth between the primary data center and the secondary data center. The method further includes storing the first portion of data in a first cache associated with the first access point. The method also includes transmitting the first portion of data from the first cache to the secondary data center. A system and non-transitory computer-readable medium are also provided.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: April 24, 2018
    Assignee: VMware, Inc.
    Inventor: Rajesh Singh
  • Publication number: 20170280712
    Abstract: The present application relates to a nanoparticle compositions and methods for targeted delivery of a bioactive agent to a plant. In one embodiment, the nanoparticle composition includes a coronatine-coated nanoparticle formulated to deliver one or more bioactive agent through plant stomata. A variety of bioactive agents may be included in the nanoparticles, including one or more bactericides, fungicides, insecticides, acaricides, miticides, nemanticides, molluscicides, herbicides, plant nutrients, fertilizers, plant growth regulators, or combinations thereof.
    Type: Application
    Filed: March 27, 2017
    Publication date: October 5, 2017
    Inventors: James W. LILLARD, JR., Rajesh SINGH
  • Patent number: 9442620
    Abstract: This disclosure describes tools for navigating within applications, and in particular business applications. For example, a menu system may incorporate a notification system, such that notifications of events received at a business application are displayed within the context of the menu system. The user can be allowed to select an event from the menu system, allowing the user to quickly navigate to a context, within the application, corresponding to the event.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: September 13, 2016
    Assignee: ORACLE INTERNATIONAL CORPORATION
    Inventors: Nigel King, Steven Miranda, Rajesh Singh
  • Publication number: 20160203060
    Abstract: A system and method for deploying clients at a target site with disaster recovery considerations uses recovery profiles with multiple recovery parameter settings, which can be associated with a client to be deployed. The recovery profile associated with the client is used to automatically initiate a recovery-related operation for the client using a recovery parameter setting defined in the recovery profile associated with the client.
    Type: Application
    Filed: March 11, 2015
    Publication date: July 14, 2016
    Inventors: RAJESH SINGH, Girish Ramchandra Rao, Puneet Gupta
  • Publication number: 20160188689
    Abstract: A method for copying first data stored at a primary data center to a secondary data center is provided. The method includes initiating a first replication task to copy the first data from the primary data center to the secondary data center. The method also includes receiving a first portion of the first data from the primary data center via a first access point, wherein a first bandwidth between the primary data center and the first access point is greater than a second bandwidth between the primary data center and the secondary data center. The method further includes storing the first portion of data in a first cache associated with the first access point. The method also includes transmitting the first portion of data from the first cache to the secondary data center. A system and non-transitory computer-readable medium are also provided.
    Type: Application
    Filed: February 27, 2015
    Publication date: June 30, 2016
    Inventor: Rajesh Singh
  • Publication number: 20160139130
    Abstract: Methods for detecting cancer or monitoring cancer progression in a subject are disclosed. The method includes detecting the level of expression of one or more cancer markers in a biological sample obtained from the subject; and comparing the level of expression of the one or more cancer markers in the biological sample to a normal level of expression of the one or more cancer markers. The one or more cancer markers comprises CXCL16 or CXCR6 or both CXCL16 and CXCR6. Also disclosed is a kit for detecting cancer or monitoring cancer progression.
    Type: Application
    Filed: September 25, 2015
    Publication date: May 19, 2016
    Inventors: James W. LILLARD, JR., Shailesh Singh, Rajesh Singh
  • Publication number: 20160063419
    Abstract: This disclosure generally relates to devices, systems, and computer-implemented methods for simulating one or more inventories in a distribution network. Specifically, methods are described that comprise the operations of receiving inventory data for one or more inventories to be simulated, wherein the inventory data includes lead time data and demand data; determining, based on the inventory data, probability distributions for each of lead time and demand for the one or more inventories to be simulated; determining a lead time demand probability distribution of the one or more inventories to be simulated based on the determined probability distributions for the lead time and the demand; determining a predictive state of the one or more inventories to be simulated based on the lead time demand probability distribution; and outputting one or more evaluation parameters associated with the predictive state of the one or more inventories to be simulated.
    Type: Application
    Filed: August 25, 2015
    Publication date: March 3, 2016
    Inventors: Yair Martinez, Javier Subira Escrig, Dario Romare, Jaime Lagunas, Robert Gimeno, Ghanshyam Devnani, Rajesh Singh