Abstract: The present invention relates to clinically proven subcutaneous pharmaceutical compositions comprising anti-CD38 antibodies and methods of their uses in combination with bortezomib and dexamethasone.

Abstract: Techniques are disclosed herein for creating over and under interconnects. Using techniques described herein, over and under interconnects are created on an IC. Instead of creating signaling interconnects and power/ground interconnects on a same side of a chip assembly, the signaling interconnects can be placed on an opposing side of the chip assembly as compared to the power interconnects.

Abstract: Systems, methods and computer software are disclosed for providing a bubble network are described. In one embodiment, a method is disclosed including providing an isolated base station having a coverage area, providing a local HetNet Gateway (HNG) disposed within the coverage area and in communication with the isolated base station, providing a local Evolved Packet Core (EPC) in communication with the local HNG and disposed within the coverage area, and wherein the bubble network is disconnected from a mobile operator core network.

Abstract: The present invention relates to pharmaceutical compositions of Eliglustat. In particular the present invention relates to stable amorphous Eliglustat premix having enhanced stability and dissolution properties. The present invention also provide a stable premix composition comprising amorphous Eliglustat or a pharmaceutical acceptable salt thereof, pharmaceutical compositions comprising the premixes, and processes for preparing the same. The compositions prepared in the present invention includes sublingual or mouth dissolving tablets, and capsules of Eliglustat and/or its pharmaceutically acceptable salts thereof and at least one pharmaceutically acceptable carrier.

Abstract: Techniques are described for providing wireless network connectivity using a distributed mobility management functionality. In one example, each of a plurality of on-premise access points co-locate a mobility management functionality and a packet routing and forwarding functionality. Each of the plurality of on-premise access points obtain, from user equipment, a request to wirelessly connect to the on-premise access point. Each of the plurality of on-premise access points provide the user equipment with wireless network connectivity using the co-located mobility management functionality and the packet routing and forwarding functionality.

Abstract: In one embodiment, an apparatus includes an input/output virtualization (IOV) device comprising: at least one function circuit to be shared by a plurality of virtual machines (VMs); and a plurality of assignable device interfaces (ADIs) coupled to the at least one function circuit, wherein each of the plurality of ADIs is to be associated with one of the plurality of VMs and comprises a first process address space identifier (PASID) field to store a first PASID to identify a descriptor queue stored in a host address space and a second PASID field to store a second PASID to identify a data buffer located in a VM address space. Other embodiments are described and claimed.

Abstract: Some embodiments include a method comprising using a first computing device to perform: obtaining an image of a scene captured using a camera coupled to the first computing device; obtaining camera setting values used to capture the image; determining, using the image, surface attribute values characterizing at least one surface shown in the image of the scene; generating an augmented reality (AR) interface at least in part by using the camera setting values and the surface attribute values to create a first composite image by overlaying a selected virtual furniture object onto the image so that the virtual furniture object is displayed in the AR interface as being on a first surface of the at least one surface shown in the image; and transmitting, to a second computing device and via at least one communication network, the first composite image, the camera setting values and the surface attribute values.

Abstract: A method for converting data via a centralized application programming interface (“API”) is provided. The method may include retrieving data files from two or more data repositories and transmitting the data files to the centralized API. For each of the data files, the method may include selecting a conversion application and executing the conversion application to convert the data files into secure data files. The executing may include converting sensitive data strings into fictional data strings. Each of the sensitive data strings may include a first sub-set of characters and a second sub-set of characters. The converting may include, for each of the sensitive data strings, replacing the first sub-set of characters with a third sub-set of characters and maintaining the second sub-set of characters. Following the converting, the method may include transmitting the secure data files to an external network.

Abstract: Techniques for generating a layout of a multi-port memory cell are provided. A specification describing at least on port within a memory cell is defined. A base memory cell including at least one extension point is modeled. A port that interfaces with the base memory cell is identified from the specification. An electrical interface between the identified port and an extension point of the base memory cell is modeled. In some embodiments, a design bucket is selected from among a predefined set of design buckets based on a count of ports within the memory cell, as described by the specification. Each design bucket corresponding to a respective layout template including the base memory cell and a respective maximum count of ports. Each electrical interface including a port described in the specification of the memory cell is modeled based on the selected design bucket and the respective layout template.

Abstract: Compounds of Formulae I? and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.

Abstract: The present disclosure relates to 1,2-dihydro-3H-pyrazol-3-one compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.

Abstract: The present disclosure is directed toward a method that includes acquiring current dynamic characteristics of a moving object about an un-signalized intersection, determining a dynamic traffic flow of the un-signalized intersection based on the current dynamic characteristics to determine a position of the moving object about the un-signalized intersection, and predicting future dynamic characteristics of the moving object based on the dynamic traffic flow and a predictive control. The future dynamic characteristics includes a predicted position of the moving object at a predefined time in the future. The method further calculates an entry parameter for a vehicle about an entrance of the un-signalized intersection based on the dynamic traffic flow and the predicted future dynamic characteristics and notifies the vehicle of the entry parameter.

Abstract: A fiber optic distribution cable includes a central inner jacket formed from one of a polyvinyl chloride or a low smoke zero halogen material, a plurality of optical fibers disposed within the inner jacket, and a plurality of first strength members disposed within the inner jacket. The fiber optic distribution cable further includes an outer jacket surrounding the central inner jacket, the outer jacket formed from the one of the polyvinyl chloride or the low smoke zero halogen material, and a plurality of second strength members disposed between the outer jacket and the central inner jacket. A fiber density of the cable is greater than 0.65 fibers per square millimeter.

Abstract: A method for detecting a gene fusion includes amplifying a nucleic acid sample in the presence of primer pool to produce a plurality of amplicons. The primer pool includes primers targeting a plurality of exon-exon junctions of a driver gene. The amplicons correspond to the exon-exon junctions. The amplicons are sequenced and aligned to a reference sequence. The number of reads corresponding to each amplicon is normalized to give a normalized read count. A baseline correction is applied to the normalized read counts for the amplicons to form corrected read counts. A binary segmentation score is calculated for each corrected read count. A predicted breakpoint for the gene fusion is determined based on the amplicon index corresponding to the maximum absolute binary segmentation score. Gene fusion events may be detected in a partner agnostic manner, i.e. without prior knowledge of the specific fusion partner genes or specific breakpoint information.

Abstract: A multi-pin wafer level chip scale package is achieved. One or more solder pillars and one or more solder blocks are formed on a silicon wafer wherein the one or more solder pillars and the one or more solder blocks all have a top surface in a same horizontal plane. A pillar metal layer underlies the one or more solder pillars and electrically contacts the one or more solder pillars with the silicon wafer through an opening in a polymer layer over a passivation layer. A block metal layer underlies the one or more solder blocks and electrically contacts the one or more solder pillars with the silicon wafer through a plurality of via openings through the polymer layer over the passivation layer wherein the block metal layer is thicker than the pillar metal layer.

Abstract: This application relates generally to automated systems and methods for identifier propagation across uniform resource locator requests. In an embodiment, a system includes at least one processor operatively coupled with a datastore, the at least one processor configured to receive, from a user device, a request message comprising a request component uniform resource locator. The at least one processor is further configured to produce a redirect uniform resource locator in response to the request message not comprising a session identifier, where the redirect uniform resource locator comprises a current session identifier appended to the request component uniform resource locator. The at least one processor is further configured to send, to the user device, a redirection instruction comprising the redirect uniform resource locator, where the redirection instruction indicates that a resource requested by the request message has been temporarily moved to the redirect uniform resource locator.

Abstract: Methods and system perform tool tracking during minimally invasive robotic surgery. Tool states are determined using triangulation techniques or a Bayesian filter from either or both non-endoscopically derived and endoscopically derived tool state information, or from either or both non-visually derived and visually derived tool state information. The non-endoscopically derived tool state information is derived from sensor data provided either by sensors associated with a mechanism for manipulating the tool, or sensors capable of detecting identifiable signals emanating or reflecting from the tool and indicative of its position, or external cameras viewing an end of the tool extending out of the body. The endoscopically derived tool state information is derived from image data provided by an endoscope inserted in the body so as to view the tool.

Abstract: Systems, methods, media, and other such embodiments described herein relate to improved operation of test devices which verify circuit operations. One embodiment involves accessing a circuit design comprising a plurality of instances of one or more blocks, where each block of the one or more blocks is associated with a corresponding block test pattern comprising one or more test subpatterns. Each corresponding block test pattern is processed to identify independent test subpatterns, and then each instance is processed to identify each independent test subpattern for the circuit design. Similar types of independent test subpatterns are merged into a circuit design test pattern, such that at least two of the independent test subpatterns associated with the circuit design occupy shared test cycles within the circuit design test pattern.

Abstract: A sequence mining platform (SMP) comprises a processor, at least one machine-accessible storage medium responsive to the processor, and a sequence manager in the machine-accessible storage medium. The sequence manager is configured to use processing resources to determine a sequence of nucleobases in a nucleic acid. The storage medium also comprises a blockchain manager to (a) collect transaction data for one or more transactions for a blockchain which requires a proof of work (POW) for each new block; and (b) include at least some of the transaction data in a new block for the blockchain. The storage medium also comprises a sequence mining module (SMM) to use the determined sequence of nucleobases from the sequence manager to create a POW for the new block. In one embodiment, the SMM enables an entity which controls the SMP to receive transaction rewards and sequencing rewards. Other embodiments are described and claimed.

Abstract: Embodiments provide a computer-executable method, computer system and non-transitory computer-readable medium for programmatically generating an association among two or more purchase categories based on purchase data of a plurality of consumers. The method includes programmatically accessing, from a dataset via a network device, prior purchase data associated with purchases of a plurality of commercial objects by a plurality of consumers. The method also includes programmatically identifying a plurality of categories associated with the plurality of commercial objects. The method also includes, for each consumer in the plurality of consumers, programmatically generating a total number of purchases by the consumer in each category in the plurality of categories.