Abstract: A novel method of treating diseases characterized by high PAI-1 is presented. Administering a composition comprising a therapeutically effective amount of genistein was found to inhibit PAI-1 promotor activity and decrease PAI-1 levels to treat diseases such as asthma, which exhibit increased PAI-1 levels. Genotyping the patient can be performed prior to administration to detect a 4G/5G polymorphism as patients having a 4G genotype have better response to the genistein treatment. The composition may be comprised of a therapeutically effective amount of genistein derived naturally from soybeans or synthetically produced and optionally present in nanoparticle form.

Abstract: A data processing and analysis system that optimizes the resources to be used for data storage and refresh events. A partitioner module for a data analysis system can receive a first client criteria and a first client dataset that includes tabular data and calculate scores that are used to generate partitioning strategies. The selected partitioning strategy can be implemented to produce aggregated data that can be stored in an intelligent data mart. The partitions can then be accessed by a data visualization platform for intelligent, dynamic responses to user requests for data analyses and generation of visualizations. By providing synchronous partitioning of data (especially big data) and intelligent refresh, the data can move from the back-end to the front-end with minimal user clicks and minimal latency in performance.

Abstract: A fiber optic distribution cable includes a central inner jacket formed from one of a polyvinyl chloride or a low smoke zero halogen material, a plurality of optical fibers disposed within the inner jacket, and a plurality of first strength members disposed within the inner jacket. The fiber optic distribution cable further includes an outer jacket surrounding the central inner jacket, the outer jacket formed from the one of the polyvinyl chloride or the low smoke zero halogen material, and a plurality of second strength members disposed between the outer jacket and the central inner jacket. A fiber density of the cable is greater than 0.65 fibers per square millimeter.

Abstract: Modified zeolites may include a microporous framework including a plurality of micropores having diameters of less than or equal to 2 nm. The microporous framework may include at least silicon atoms and oxygen atoms. The modified zeolite may include a plurality of mesopores having diameters of greater than 2 nm and less than or equal to 50 nm, wherein the plurality of mesopores are ordered with cubic symmetry. The modified zeolite may include a plurality of hafnium hydride moieties each bonded to at least two bridging oxygen atoms, wherein a hafnium atom of the hafnium hydride is bonded to the bridging oxygen atom, and wherein the bridging oxygen atom bridges the hafnium atom of the hafnium hydride moiety and a silicon atom of the microporous framework.

Abstract: Mechanisms are provided for automated document image annotation and data extraction. A received document image is processed to identify a document type of the received document image, and retrieve a corresponding document template having key point location data and annotation location data for documents of the document type. First key points of the received document image are matched with second key points of the corresponding document template and a mapping is generated to map locations of the document template to locations of the received document image. A perspective transformation is applied, based on the mapping, to first annotation locations specified in the document template data structure to generate second annotation locations corresponding to locations in the received document image. Data extraction is performed on data associated with the second annotation locations based on the annotations corresponding to the second annotation locations.

Abstract: A method for synchronizing a file system (FS) and a remote file system (RFS) includes monitoring the FS for FS events, generating FS event records, receiving RFS event records of RFS events, generating file system operations (FSOs) based on the FS and RFS event records, and communicating the FSOs to the FS and RFS to synchronize them. A method for generating the FSOs includes accessing a plurality of FS and/or RFS event records, processing the accessed records to generate processed event records, generating the FSOs based on the processed event records, and outputting the FSOs to cause synchronization of the FS and RFS. Systems are also described. The invention facilitates event-based, steady-state synchronization of local and remote file systems.

Abstract: The invention provides a lateral flow device and methods for the detection of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a sample of bodily fluid of an animal or human. The test methods include contacting the sample with a conjugate comprising a recombinant SARS-CoV-2 spike protein antigen that has been conjugated to a detection agent, wherein an antigen-antibody complex is formed between the SARS-CoV-2 spike protein antigen conjugate and SARS-CoV-2 antibodies present in the sample; capturing the formed antigen-antibody complex with an Fc-binding molecule; and detecting the captured complex.

Abstract: A system and method for hydraulic fracturing a subterranean formation with fracturing fluid to generate fractures, and intermittently adjusting a characteristic of the fracturing fluid conveying proppant to form pillars of proppant in the fractures.

Abstract: Techniques that enable a hypervisor to (1) maintain shared memory pages and (2) handle memory accounting for VMs that are suspended to and resumed from the volatile memory of a host system are provided. Regarding (1), the hypervisor can maintain shared memory pages in volatile memory across the suspend-to-memory and resume-from-memory operations, without having to save their reference counts. Regarding (2), the hypervisor can keep track of the volatile memory reserved and consumed by VMs as they are suspended and resumed, without erroneously double counting that memory.

Abstract: A mechanism is described for facilitating misuse index for explainable artificial intelligence in computing environments, according to one embodiment. A method of embodiments, as described herein, includes mapping training data with inference uses in a machine learning environment, where the training data is used for training a machine learning model. The method may further include detecting, based on one or more policy/parameter thresholds, one or more discrepancies between the training data and the inference uses, classifying the one or more discrepancies as one or more misuses, and creating a misuse index listing the one or more misuses.

Abstract: Disclosed are various approaches for decreasing the latency involved in reading pages from swap devices. These approaches can include setting a first queue in the plurality of queues as a highest priority queue and a second queue in the plurality of queues as a low priority queue. Then, an input/output (I/O) request for an address in memory can be received. The type of the I/O request can be determined, and then the I/O request can be assigned to the first queue or the second queue of the swap device based at least in part on the type of the I/O request.

Abstract: A minimally invasive blood clot capturing invention made of nitinol. The nitinol is shaped into a plurality of fingers to form a frame for a basket and funnel to capture and remove blood clots. The basket and funnel being delivered to the blood clot by a catheter. The basket and funnel are capable of being collapsed within a catheter capable of being deployed into a blood vessel, and capable of being retracted into the catheter for removal from the blood vessel.

Abstract: Techniques are provided for processing read operations while splitting a clone volume from a parent volume whose data is stored within objects of an object store. A transfer map is created to track mappings of child object identifiers to parent object identifiers of the parent objects to copy as child objects having the child object identifiers. The transfer map for the object store is traversed to copy the parent objects as the child objects for the split clone operation. The child objects are verified as being successfully created with valid data. In response to determining that the parent object has been copied as the child object, a context check is performed using the reverse map to verify a block within the child object. In response a successful context check, the read operation is processed using the block of the child object.

Abstract: A microelectronic device comprises a stack structure comprising insulative levels vertically interleaved with conductive levels. The conductive levels individually comprise a first conductive structure, and a second conductive structure laterally neighboring the first conductive structure, the second conductive structure exhibiting a concentration of ?-phase tungsten varying with a vertical distance from a vertically neighboring insulative level. The microelectronic device further comprises slot structures vertically extending through the stack structure and dividing the stack structure into block structures, and strings of memory cells vertically extending through the stack structure, the first conductive structures between laterally neighboring strings of memory cells, the second conductive structures between the slot structures and strings of memory cells nearest the slot structures. Related memory devices, electronic systems, and methods are also described.

Abstract: A method of operating a server is provided that includes providing, with the server, one or more services relating to network access control and management of a network, predicting a network configuration failure associated with the network with a failure prediction model, and generating a network configuration recommendation based on the predicted network configuration failure to avoid the predicted network configuration failure. The failure prediction model can be a machine-learning based network configuration failure prediction model that is trained on past network configuration failure events. Operated in this way, erroneous network configuration issues can be automatically identified and addressed in a timely fashion.

Abstract: A device access management server may facilitate secure access of a target device by an accessing device. The secure remote access of the target device by the accessing device may be facilitated by a public key infrastructure (PKI) certificate issued and/or validated by the device access management server.

Abstract: A method of operating a network is provided that includes identifying a plurality of client devices connected to the network, categorizing the client devices into respective client groups based on device characteristics of each of the client devices, analyzing traffic patterns among the client groups and assigning the client groups to respective network segments based on the observed traffic patterns, and generating one or more network access policy for at least one of the network segments based on the traffic patterns or baseline behavior associated with a portion of the client devices belonging to the at least one of the network segments.

Abstract: Methods, apparatus, and processor-readable storage media for automatically detecting data anomalies using artificial intelligence techniques are provided herein. An example computer-implemented method includes obtaining data pertaining to multiple tasks associated with at least one enterprise; detecting one or more data anomalies by predicting one or more values within the obtained data by processing at least a portion of the obtained data using one or more artificial intelligence techniques, and comparing the one or more predicted values to one or more corresponding portions of the obtained data; generating one or more data recommendations associated with at least a portion of the one or more detected data anomalies; and performing one or more automated actions based at least in part on at least one of the one or more detected data anomalies and the one or more generated data recommendations.

Abstract: In some implementations, the disclosed techniques may include tuning a first antenna element to a first tuning state during an acquisition mode for establishing communication channels with satellites. The first tuning state can configure the first antenna element to receive signals in a first frequency range. The techniques may include establishing the communication channels using the first antenna element in the first tuning state during the acquisition mode. The techniques may include transitioning from the acquisition mode to a tracking mode. The techniques may include changing the tuning state of the first antenna element. The techniques may include determining a location of the mobile device during the tracking mode: (1) using the first antenna element and a second antenna element of the mobile device or (2) not using the first antenna element and using the second antenna element that is configured to receive signals in a second frequency range.

Abstract: Provided is pharmaceutical composition for treating a pain disorder in a subject in need thereof, wherein the pharmaceutical composition includes a therapeutically active ingredient including an intranasally bioavailable CGRP inhibitor. Also provided is a method of treating a pain disorder in a subject in need thereof, wherein the method includes intranasally administering to the subject a composition including a therapeutically active component including an intranasally bioavailable CGRP inhibitor.