Abstract: Compounds of formula I that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase, pharmaceutical compositions including such compounds and methods of treating diseases, conditions or disorders utilizing such compounds and compositions.

Abstract: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Abstract: Compounds of formula I that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase, pharmaceutical compositions including such compounds and methods of treating diseases, conditions or disorders utilizing such compounds and compositions.

Abstract: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Abstract: The compounds are of the class of 3,7 substituted benzoxaboroles, useful for killing and/or inhibiting the growth of microorganisms.

Abstract: Compositions and methods are provided for assessing the presence or absence, and optionally quantitating, the surface loading of a noble metal such as platinum on the surface of a substrate. The invention utilizes the decomposition rate of hydrogen peroxide (H2O2) or other redox active molecule following exposure to the substrate surface to effectively establish a qualitative or quantitative correlation between the redox agent survival fraction and the presence or absence of noble metal (e.g., platinum), and further, for the quantitation of noble metal loading on the substrate surface. The invention finds applicability in assessing the surface loading of noble metals on the internal surfaces of boiling water nuclear reactor plants (BWR) that have undergone prior noble metal application.

Abstract: The present invention provides compositions and methods for assessing the presence or absence, and optionally quantitating, the surface loading of a noble metal such as platinum on the surface of a substrate. The invention utilizes the decomposition rate of hydrogen peroxide (H2O2) or other redox active molecule following exposure to the substrate surface to effectively establish a qualitative or quantitative correlation between the redox agent survival fraction and the presence or absence of noble metal (e.g., platinum), and further, for the quantitation of noble metal loading on the substrate surface. The invention provides advantages over the state of the art, and finds applicability in diverse industries. In some embodiments, the compositions and/or methods of the invention are used to assess the surface loading of noble metals on the internal surfaces of boiling water nuclear reactor plants (BWR) that have undergone prior noble metal application.

Abstract: Techniques are presented for establishing context awareness during first negotiation of secure key exchange. These techniques may be embodied as a method, apparatus or instructions in a computer-readable storage media. At a first network device, a message is received from a second network device as part of an initial exchange of information of a secure key exchange, the message containing information indicating one or more secure key exchange policies acceptable to the second network device and defining one or more associated security parameters. The message further contains context-specific information identifying a context of the second network device. The first network device selects a secure key exchange policy for communicating with the second network device based upon the context-specific information and sends a response message to the second network device containing the selected secure key exchange policy. If the context was understood, the response message also includes context-specific information.

Abstract: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Abstract: Techniques are presented for establishing context awareness during first negotiation of secure key exchange. These techniques may be embodied as a method, apparatus or instructions in a computer-readable storage media. At a first network device, a message is received from a second network device as part of an initial exchange of information of a secure key exchange, the message containing information indicating one or more secure key exchange policies acceptable to the second network device and defining one or more associated security parameters. The message further contains context-specific information identifying a context of the second network device. The first network device selects a secure key exchange policy for communicating with the second network device based upon the context-specific information and sends a response message to the second network device containing the selected secure key exchange policy. If the context was understood, the response message also includes context-specific information.

Abstract: Novel monosubstituted and disubstutituted oxaboroles and pharmaceutical compositions containing such oxaboroles are provided, which are useful for treating bacterial infections, as well as combinations of these oxaboroles with at least one additional therapeutically effective agent.

Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.

Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.

Abstract: This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.

Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.

Abstract: Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.

Abstract: Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

Abstract: This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.

Abstract: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.