Patents by Inventor Ralf Engelmann

Ralf Engelmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060012870
    Abstract: Light scanning microscope for recording at least one sample area by a relative movement between illumination light and sample, whereby an illumination light illuminated the sample in parallel in several spots or areas and several spots or areas are simultaneously detected with a detector arrangement and several illuminated sample points lie on a line and several points are simultaneously detected with a detector having local resolution whereby detection beams are provided with replaceable and/or switchable beam splitters and/or filters.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Engelmann, Ralf Wolleschensky, Joerg Steinert, Dieter Schau
  • Publication number: 20060013491
    Abstract: Process for the acquisition of images from a probe with a light scanning electron microscope with linear scanning, wherein detected image data that correspond to three dimensional probe regions are detected and stored to memory, wherein data compression ensues in that the data of images lying next to one another and over one another on the probe are taken into consideration during compression. A stack of images is advantageously recorded and images that are respectively adjacent in the image stack are consulted for the compression of data. Temporally and/or spectrally detected and stored data shall be consulted for the compression of data.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Frank Hecht, Ralf Engelmann, Ralf Wolleschensky
  • Publication number: 20060011857
    Abstract: Raster Scanning Light Microscope with line pattern scanning with at least one illumination module, in which the means to achieve a variable partition of the laser light into least two illumination channels are envisioned and joint illumination of a sample takes place at the same or at different areas of the sample.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Joerg-Michael Funk, Ralf Wolleschensky, Bernhard Zimmermann, Stefan Wilhelm, Ralf Engelmann
  • Publication number: 20060011859
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope with line by line scanning, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Publication number: 20060011824
    Abstract: Process for the observation of at least one sample region with a light raster microscope by a relative movement between the illumination light and sample via first scanning means along at least one scanning axis essentially perpendicular to the illumination axis wherein the illumination light illuminates the sample in parallel at several points or regions and several points or regions are detected simultaneously wherein at an angle to the plane of the relative movement, preferably perpendicular thereto, second scanning means are moved and an image acquisition takes place by the movement of the first and second scanning means being coupled and a three-dimensional sampling movement being done by the illumination of the sample wherein the second scanning means are coupled to the movement of the first scanning means in such a manner that straight and/or curved lines and/or plane and/or curved surfaces are scanned which are extended along at least one scanning direction of the first scanning means as well as along
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Engelmann, Joerg-Michael Funk, Joerg Steinert, Bernhard Zimmermann, Stefan Wilhelm, Joerg Engel, Ulrich Meisel
  • Publication number: 20060012864
    Abstract: Raster Scanning Light Microscope with line pattern scanning with at least one illumination module, in which the means to achieve a variable partition of the laser light into least two illumination channels are envisioned and joint illumination of a sample takes place at the same or at different areas of the sample.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Joerg-Michael Funk, Ralf Wolleschensky, Bernhard Zimmermann, Stefan Wilhelm, Ralf Engelmann
  • Publication number: 20060011858
    Abstract: Process for the observation of at least one sample region with a light raster microscope by a relative movement between the illumination light and sample via first scanning means along at least one scanning axis essentially perpendicular to the illumination axis wherein at an angle to the plane of the relative movement, preferably perpendicular thereto, second scanning means are moved and an image acquisition takes place by the movement of the first and second scanning means being coupled and a three-dimensional sampling movement being done by the illumination of the sample wherein the second scanning means are coupled to the movement of the first scanning means in such a manner that straight and/or curved lines and/or plane and/or curved surfaces are scanned which are extended along at least one scanning direction of the first scanning means as well as along the scanning direction of the second scanning means.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Engelmann, Joerg-Michael Funk, Joerg Steinert, Bernhard Zimmermann, Stefan Wilhelm, Joerg Engel, Ulrich Meisel
  • Publication number: 20060011860
    Abstract: Process for the acquisition of images from a probe with a microscope, wherein detected image data that correspond to three dimensional probe regions are detected and stored to memory, wherein data compression ensues in that the data of images lying next to one another and over one another on the probe are taken into consideration during compression. A stack of images is advantageously recorded and images that are respectively adjacent in the image stack are consulted for the compression of data. Temporally and/or spectrally detected and stored data shall be consulted for the compression of data.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Frank Hecht, Ralf Engelmann, Ralf Wolleschensky
  • Publication number: 20060012874
    Abstract: Raster Scanning Light Microscope with punctiform light source distribution with at least one illumination module, in which the means to achieve a variable partition of the laser light into least two illumination channels are envisioned and joint illumination of a sample takes place at the same or at different areas of the sample.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Joerg-Michael Funk, Ralf Wolleschensky, Bernhard Zimmermann, Stefan Wilhelm, Ralf Engelmann
  • Publication number: 20060011812
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope with punctual light source distribution, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Publication number: 20060012862
    Abstract: Light scanning microscope for recording at least one sample area by a relative movement between illumination light and sample, whereby an illumination light illuminated the sample in parallel in several spots or areas and several spots or areas are simultaneously detected with a detector arrangement whereby the illumination light consists of a distribution of spot-shaped light sources and the illumination sample spots are assigned to detectors on the detection side whereby detection beams are provided with replaceable and/or switchable beam splitters and/or filters.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Engelmann, Ralf Wolleschensky, Joerg Steinert, Dieter Schau
  • Publication number: 20050072913
    Abstract: Laser scanning microscope with at least four separate input-coupling locations for wavelength ranges in the UV region, in the visible region and in the IR region, and advantageously with at least two individually displaceable collimators for achieving a maximum flexibility in the selection of dyes and evaluating methods, preferably for displaying cellular calcium and the associated receptors in living tissue over long periods of time (time lapse) with infrared lasers and UV lasers, wherein fluorescence detection and uncaging are applied, for releasing drugs (uncaging) and IR illumination with transmission detection, for the realization of applications with fluorescing proteins of the (G)FP family, including photoactivation of GFP and CFP/YFP-FRET, for the use of CY 5.5 dyes in the dark-red region (laser 675 nm) for tumor research.
    Type: Application
    Filed: July 9, 2004
    Publication date: April 7, 2005
    Inventors: Ralph Lange, Thomas Mehner, Stefan Wilhelm, Ralf Wolleschensky, Ralf Engelmann
  • Publication number: 20050058372
    Abstract: A method for the operation of a laser scanning microscope and for the detection of a specimen, wherein at least two detected images or image areas are compared to one another and temporal and/or spatial changes in the color and/or intensity lead to the formation of control signals for the illumination and/or detection and/or scanner control and/or other adjustable microscope components, and a laser scanning microscope with detection structure for detecting spatial and/or temporal changes in a specimen and/or in a specimen area and a control element for controlling the illumination and/or detection and/or scanner control and/or other optical and/or electronic microscope components depending on the detected change.
    Type: Application
    Filed: July 9, 2004
    Publication date: March 17, 2005
    Inventors: Ralf Engelmann, Joerg Engel