Patents by Inventor Ralf Schumacher

Ralf Schumacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10344085
    Abstract: Herein are reported humanized anti-IL-1beta antibodies that are humanized variants of the murine anti-IL-1beta antibody H34. A specific humanized antibody comprises (a) a HVR-H1 comprising the amino acid sequence of SEQ ID NO: 25, (b) a HVR-H2 comprising the amino acid sequence of SEQ ID NO: 27, and (c) a HVR-H3 comprising the amino acid sequence of SEQ ID NO: 28.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: July 9, 2019
    Assignee: Hoffman-La Roche, Inc.
    Inventors: Stefan Dengl, Peter Michael Huelsmann, Christian Gassner, Sebastian Breuer, Olaf Mundigl, Guy Georges, Ralf Schumacher, Guido Hartmann, Sabine Gruener
  • Patent number: 10082165
    Abstract: A fastener, in particular for bellows, comprises a male end segment and a female end segment complementary to the male end segment. The fastener can be used to fasten bellows to joint housings and/or shafts, said fastener having improved closing behavior.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: September 25, 2018
    Assignee: GKN Driveline International GmbH
    Inventors: Markus Deisinger, Ralf Schumacher, Joachim Wette, Daniela Ballas, Andreas Gehrke, Ludger Wenning, Achim Pfeifer, Maik Lehmann
  • Patent number: 9933095
    Abstract: A fastening means, in particular for a bellows, comprises a male end segment and a female end segment complementary to the male end segment. The fastening means can be used to fasten bellows to joint housings and/or shafts. The fastening means has an inner undercut region in order to provide an improved closing behavior of the fastening means.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: April 3, 2018
    Assignee: GKN Driveline International GmbH
    Inventors: Markus Deisinger, Ralf Schumacher, Joachim Wette, Daniela Ballas, Andreas Gehrke, Ludger Wenning, Achim Pfeifer, Maik Lehmann
  • Publication number: 20170247447
    Abstract: Herein are reported humanized anti-IL-1beta antibodies that are humanized variants of the murine anti-IL-1beta antibody H34. A specific humanized antibody comprises (a) a HVR-H1 comprising the amino acid sequence of SEQ ID NO: 25, (b) a HVR-H2 comprising the amino acid sequence of SEQ ID NO: 27, and (c) a HVR-H3 comprising the amino acid sequence of SEQ ID NO: 28.
    Type: Application
    Filed: May 9, 2017
    Publication date: August 31, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Stefan Dengl, Peter Michael Huelsmann, Christian Gassner, Sebastian Breuer, Olaf Mundigl, Guy Georges, Ralf Schumacher, Guido Hartmann, Sabine Gruener
  • Publication number: 20170240629
    Abstract: Herein are reported novel bispecific antibodies that specifically bind to two different antigens selected from the group consisting of human ANG2, human VEGF, human IL-1beta and human PDGF-B.
    Type: Application
    Filed: May 9, 2017
    Publication date: August 24, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Marc Bedoucha, Sebastian Breuer, Stefan Dengl, Christian Gassner, Guy Georges, Sabine Gruener, Guido Hartmann, Peter Michael Huelsmann, Hubert Kettenberger, Joerg Moelleken, Michael Molhoj, Olaf Mundigl, Joerg Thomas Regula, Ralf Schumacher, Barbara Weiser
  • Publication number: 20170143501
    Abstract: A scaphoid prosthesis comprises a body bounded by an outer surface, wherein the outer surface is substantially corresponding to a patient's scaphoid. The body of the scaphoid prosthesis comprises a tubular base element including a first end portion and a second end portion and a plurality of protruding portions. A passage is provided in the tubular base element for a fixation means for fixing the scaphoid prosthesis in its position. The passage is configured as a curved passage.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 25, 2017
    Inventors: Philipp Honigmann, Florian Thieringer, Ralf Schumacher, Mathias Häfeli
  • Publication number: 20170108021
    Abstract: A fastener, in particular for bellows, comprises a male end segment and a female end segment complementary to the male end segment. The fastener can be used to fasten bellows to joint housings and/or shafts, said fastener having improved closing behavior.
    Type: Application
    Filed: October 25, 2016
    Publication date: April 20, 2017
    Inventors: Markus Deisinger, Ralf Schumacher, Joachim Wette, Daniela Ballas, Andreas Gehrke, Ludger Wenning, Achim Pfeifer, Maik Lehmann
  • Publication number: 20170037990
    Abstract: A fastening means, in particular for a bellows, comprises a male end segment and a female end segment complementary to the male end segment. The fastening means can be used to fasten bellows to joint housings and/or shafts. The fastening means has an inner undercut region in order to provide an improved closing behavior of the fastening means.
    Type: Application
    Filed: October 25, 2016
    Publication date: February 9, 2017
    Inventors: Markus Deisinger, Ralf Schumacher, Joachim Wette, Daniela Ballas, Andreas Gehrke, Ludger Wenning, Achim Pfeifer, Maik Lehmann
  • Patent number: 9494199
    Abstract: A rolling boot comprises a first fastening region for fastening the boot to a joint casing, a second fastening region for fastening the boot to a shaft, and a fold region between the first and the second fastening region with a first fold near to the first fastening region and a second fold near to the second fastening region. The boot further comprises, between the first fastening region and the first fold, a first transition region comprising a first flange neighboring the first fastening region with a bottom. A ratio between a first minimal diameter D1, defined by the bottom of the first flange of the first transition region, and a second maximal diameter D2, defined by the first fold, where both are viewed in a longitudinal section direction along the main axis, is between approximately 1:1.01 to approximately 1:1.25.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: November 15, 2016
    Assignee: GKN Driveline International GmbH
    Inventors: Ralf Schumacher, Winfried Busch, Markus Deisinger, Joachim Wette, Wolfgang Hildebrandt, Thomas Schafferus, Achim Schmeink
  • Patent number: 9263861
    Abstract: A module latching arrangement for mounting and dismounting on a generally U-shaped support rail at least two module base bodies arranged orthogonally above and extending transversely across the support rail, each of the base bodies having a pair of bottom corner portions arranged on opposite sides of the support rail. At least one foot member is connected for horizontal longitudinal sliding movement relative to one of the base body corner portions relative to the adjacent support rail horizontal flange portion. A lateral displacement arrangement on the foot member is operable, when the foot member is displaced from a locked position toward an unlocked position relative to the support rail, to displace the first base body laterally away from an adjacent second base body mounted on the support rail. The foot member is latched in either a locked or an unlocked position relative to the base member.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: February 16, 2016
    Assignee: Weidmueller Interface GmbH & Co. KG
    Inventors: Ralf Schumacher, Klaus Wohlgemuth, Stephan Fehling, Georg Kulturidi, Matthias Niggemann, Klaus Pueschner, Marco Waldhoff
  • Patent number: 9102733
    Abstract: This invention relates to anti-OX40L antibodies and, in particular, to anti-OX40L antibodies and variants thereof that contain a Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from inflammatory diseases.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: August 11, 2015
    Assignee: Roche Palo Alto LLC
    Inventors: Joseph Endl, Elsie M. Eugui, Maria Elena Fuentes, Yvo Graus, Aran Frank Labrijn, Martin Lanzendoerfer, Paul Parren, Frank Rebers, Ralf Schumacher, Stefan Seeber, Jan Van De Winkel, Martine Van Vugt
  • Patent number: 9039869
    Abstract: A device for feeding and controlling secondary air from secondary air ducts into flue gas channels of horizontal coke oven chambers is shown. The flue gas channels are located underneath the coke oven chamber floor on which coal carbonization is realized. The flue gas channels serve for combustion of partly burnt coking gases from the coke oven chamber. The partly burnt gases are burnt with secondary air, thus heating the coke cake also from below to ensure even coal carbonization. Secondary air comes from the secondary air ducts connected to atmospheric air and to the flue gas channels. Controlling elements are mounted in the connecting channels between the flue gas channels and secondary air ducts which can precisely control the air flow into the flue gas channels. Thereby, it is possible to achieve a much more regular heating and heat distribution in coke oven chambers. The actual controlling devices in the connecting channels can be formed by turnable pipe sections, wall bricks, or metal flaps.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: May 26, 2015
    Assignee: UHDE GMBH
    Inventors: Ronald Kim, Ralf Schumacher
  • Publication number: 20150119152
    Abstract: A rolling boot comprises a first fastening region for fastening the boot to a joint casing, a second fastening region for fastening the boot to a shaft, and a fold region between the first and the second fastening region with a first fold near to the first fastening region and a second fold near to the second fastening region. The boot further comprises, between the first fastening region and the first fold, a first transition region comprising a first flange neighbouring the first fastening region with a bottom. A ratio between a first minimal diameter D1, defined by the bottom of the first flange of the first transition region, and a second maximal diameter D2, defined by the first fold, where both are viewed in a longitudinal section direction along the main axis, is between approximately 1:1.01 to approximately 1:1.25.
    Type: Application
    Filed: November 6, 2014
    Publication date: April 30, 2015
    Inventors: Ralf Schumacher, Winfried Busch, Markus Deisinger, Joachim Wette, Wolfgang Hildebrandt, Thomas Schafferus, Achim Schmeink
  • Patent number: 8986033
    Abstract: An electrical module includes a rectangular carrier frame adapted for vertical transverse mounting on a horizontal support rail, a housing for mounting an electrical component in an open-top chamber contained in the carrier frame, and a rectangular electrical connector mounted on and extending across the upper end of the carrier frame, thereby to enclose the component and afford electrical connection with upper terminals thereof. The connector is pivotally connected at one end with the carrier frame for displacement between open and closed positions, and a fastener device serves to lock the connector in the closed position to the carrier frame. Alternatively, the ends of the connector are removably fastened to the carrier frame. Lower terminals of the component are connected with lower contacts arranged at the bottom of the chamber for connection with corresponding lower contacts of adjacent modules mounted in stacked relation on the support rail.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: March 24, 2015
    Assignee: Weidmueller Interface GmbH & Co. KG
    Inventors: Timo Berger, Stephan Fehling, Georg Kulturidi, Daniela Luecke-Janssen, Matthias Niggemann, Klaus Pueschner, Michael Schnatwinkel, Ralf Schumacher, Klaus Wohlgemuth, Gordon Opitz
  • Publication number: 20140193404
    Abstract: The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof.
    Type: Application
    Filed: March 3, 2014
    Publication date: July 10, 2014
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Silke Hansen, Klaus-Peter Kuenkele, Dietmar Reusch, Ralf Schumacher
  • Patent number: 8764497
    Abstract: An electrical contact arrangement includes a planar conductive metal blank having sections that are foldable to define pairs of orthogonally arranged component contacts and bus blade contacts. Connected with a first pair of opposed side edges of a horizontal rectangular core section of the blank are a pair of rectangular component contact sections that are upwardly bent to define a pair of component contacts for receiving therebetween an electrical component, such as a printed circuit board. Connected with the orthogonally arranged second pair of opposed side edges of the core section are a pair of rectangular support sections that are bent downwardly, whereby a corresponding pair of bus blade contact sections connected with corresponding edges of the support sections extend in vertical parallel spaced relation to define a pair of bus blade contacts adapted for insertion between the downwardly bent support sections of a corresponding second electrical contact arrangement.
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: July 1, 2014
    Assignee: Weidmueller Interface GmbH & Co. KG
    Inventors: Stephan Fehling, Georg Kulturidi, Matthias Niggemann, Klaus Pueschner, Michael Schnatwinkel, Ralf Schumacher, Klaus Wohlgemuth, Marco Waldhoff, Gerhard Eggert
  • Patent number: 8703919
    Abstract: The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: April 22, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Silke Hansen, Klaus-Peter Kuenkele, Dietmar Reusch, Ralf Schumacher
  • Patent number: 8647476
    Abstract: Disclosed is a device and a method for feeding primary combustion air for the combustion of coke oven gas into a coking chamber of a coke oven of the non-recovery or heat recovery type, the coke oven is provided with openings in the oven chamber through which the oven chamber can be charged with primary air, and heating flues in the oven chamber sole with openings through which the heating flues can be charged with secondary air, and downcomer-channels which allow for guiding partially burned gas for combustion with secondary air from the oven chamber into the heating flues, wherein in the oven wall above the door or in the upper door area there are one or more non-controlled openings comprised of a heat-proof material through which part of the primary air can be guided, and in the top area of the oven there are further controllable air feeder ducts conducting primary air through the oven top.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: February 11, 2014
    Assignee: UHDE GmbH
    Inventors: Ronald Kim, Ralf Schumacher
  • Publication number: 20130216304
    Abstract: A module latching arrangement for mounting and dismounting on a generally U-shaped support rail at least two module base bodies arranged orthogonally above and extending transversely across the support rail, each of the base bodies having a pair of bottom corner portions arranged on opposite sides of the support rail. At least one foot member is connected for horizontal longitudinal sliding movement relative to one of the base body corner portions relative to the adjacent support rail horizontal flange portion. A lateral displacement arrangement on the foot member is operable, when the foot member is displaced from a locked position toward an unlocked position relative to the support rail, to displace the first base body laterally away from an adjacent second base body mounted on the support rail. The foot member is latched in either a locked or an unlocked position relative to the base member.
    Type: Application
    Filed: August 4, 2011
    Publication date: August 22, 2013
    Inventors: Ralf Schumacher, Klaus Wohlgemuth, Stephan Fehling, Georg Kulturidi, Matthias Niggemann, Klaus Pueschner, Marco Waldhoff
  • Publication number: 20130109252
    Abstract: An electrical contact arrangement includes a planar conductive metal blank having sections that are foldable to define pairs of orthogonally arranged component contacts and bus blade contacts. Connected with a first pair of opposed side edges of a horizontal rectangular core section of the blank are a pair of rectangular component contact sections that are upwardly bent to define a pair of component contacts for receiving therebetween an electrical component, such as a printed circuit board. Connected with the orthogonally arranged second pair of opposed side edges of the core section are a pair of rectangular support sections that are bent downwardly, whereby a corresponding pair of bus blade contact sections connected with corresponding edges of the support sections extend in vertical parallel spaced relation to define a pair of bus blade contacts adapted for insertion between the downwardly bent support sections of a corresponding second electrical contact arrangement.
    Type: Application
    Filed: July 13, 2011
    Publication date: May 2, 2013
    Applicant: WEIDMUELLER INTERFACE GMBH & CO. KG
    Inventors: Stephan Fehling, Georg Kulturidi, Matthias Niggemann, Klaus Pueschner, Michael Schnatwinkel, Ralf Schumacher, Klaus Wohlgemuth, Marco Waldhoff, Gerhard Eggert