Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: A fuel injection nozzle is connected to a pump for injecting the fuel and to a fresh air supply for the internal combustion engine. In order to provide an injection device which allows temperature control of the injected media with a simple structure and arrangement in the motor vehicle, the injection device has an electric heating device for heating the fresh air supplied. The heating device is fluidically connected via a first hose section to the inlet side of the fresh air supply and via a second hose section to the internal combustion engine. The heating device has a layered heating block comprising at least one heat-emitting layer and at least one heat-generating layer coupled thereto in a heat-conducting manner The heat-generating layer includes at least one PTC element and conductor elements abutting opposed sides of the PTC element.

Abstract: The compact scent delivery system (300) comprises: —a compact scent delivery device (100, 200), —an air flow mixing unit (400) comprising: 5—an inlet (405) for scented air, configured to be connected to an outlet (125) of scented air of the compact scent delivery device, —an outlet (410) for mixed scented air directed at a smelling port (415), —a conduit (420) connecting the inlet for scented air and the outlet for mixed diluted scent air and 0—at least one element of: —an inlet (425) for fresh air, configured to be connected to a fresh air delivery apparatus, said inlet delivering fresh air into the scented air stream between the inlet for scented air and the outlet for mixed scented air and/or 5—an outlet (430) for waste scented air, configured to be connected to an air flow retrieval apparatus and/or a waste air exhaust, said outlet retrieving scented air from the scented air stream between the inlet for scented air and the outlet for mixed scented air to reduce the air flow either for subsequent dilution

Abstract: The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer, said method comprising: (a) determining in a tumor sample from said patient the RNA expression levels of at least 2 of the following 9 genes: UBE2C, BIRC5, RACGAP1, DHCR7, STC2, AZGP1, RBBP8, IL6ST, and MGP (b) mathematically combining expression level values for the genes of the said set which values were determined in the tumor sample to yield a combined score, wherein said combined score is indicative of a prognosis of said patient; and kits and systems for performing said method.

Abstract: A component for an injection system for mixture-compressing, spark-ignition internal combustion engines, which is used to apportion a fluid under high pressure, in particular a high-pressure line or fluid manifold. The component includes a main body on which at least one hydraulic connection is provided, at least the main body having the connection being formed by single stage or multistage forging, an interior being formed on the main body by chip-removing machining after forging and a connection channel, which intersects with the interior in an intersection region, being formed at the connection by chip-removing machining after forging. The intersection region is deburred by mechanical deburring. An injection system and a method for producing such a component are also described.

Abstract: A fluid distributor. The fluid distributor includes a base body, a high pressure output, and a connecting piece which is joined to the base body and is used for the high pressure output. The base body is formed by a forging operation. An interior space of the base body is formed at the base body by a machining operation after the forging operation. The connecting piece is processed by a machining operation. A holding element is provided, that, as a result of the machining operation, an accommodating opening, which leads from an outer side of the connecting piece through a wall of the connecting piece and is used for at least partially accommodating the holding element, and an accommodating space, into which, during assembly, a connector of an injector is at least partially insertable in a mounting direction, are formed at the connecting piece.

Abstract: A fluid distributor rail for an injection system for mixture-compressing, externally ignited internal combustion engines for metering a highly pressurized fluid. The fluid distributor rail includes a base body, and at least one connector configured on the base body. The base body with the at least one connector configured on the base body is formed by single stage or multistage forging. At least one interior space of the base body and a hydraulic fluid passage which leads into the interior space via the at least one connector configured on the base body are formed on the base body by machining after the forging. At least one element for connection is formed at least in part by mechanical cold-forming on at least one connector configured on the base body.

Abstract: A fuel distributor for a fuel injection system for mixture-compressing, spark-ignited internal combustion engines. The fuel distributor rail includes a tubular base body which is processed by forging. At the base body, a first high-pressure output, a second high-pressure output, and a third high-pressure output are provided. The second high-pressure output is situated in an offset manner opposite the first high-pressure output in a first direction along a longitudinal axis of the tubular base body at a predefined distance. The third high-pressure output is situated in an offset manner opposite the second high-pressure output in the first direction along the longitudinal axis at the predefined distance. A first and second holding element, which are used for an at least indirect fastening of the base body, are situated at the tubular base body.

Abstract: A recyclable trolley case having a folded, closable container, a handle, at least one roller mount and at least one roller, the container rests on a common planar part with a front face, a rear face, two side faces, a bottom face and a multiplicity of tabs, the container has a top face, the top face is part of the common planar part or of a further element arranged on the planar part of the container, and the container, the roller mount, the handle and, if appropriate, the at least one roller are produced from cardboard, the handle, in a position A, is integrated or recessed in the container and, in a position B, protrudes from the container, the handle can be changed reversibly from position A to position B. The method for producing the trolley case and the use thereof are also claimed.

Abstract: A fuel distributor for a fuel injection system for mixture-compressing, spark-ignited internal combustion engines. The fuel distributor rail includes a tubular base body which is processed by forging. At the base body, a first high-pressure output, a second high-pressure output, and a third high-pressure output are provided. The second high-pressure output is situated in an offset manner opposite the first high-pressure output in a first direction along a longitudinal axis of the tubular base body at a predefined distance. The third high-pressure output is situated in an offset manner opposite the second high-pressure output in the first direction along the longitudinal axis at the predefined distance. A first and second holding element, which are used for an at least indirect fastening of the base body, are situated at the tubular base body.

Abstract: A component for an injection system for mixture-compressing, spark-ignition internal combustion engines, which is used to apportion a fluid under high pressure, in particular a highpressure line or fluid manifold. The component includes a main body on which at least one hydraulic connection is provided, at least the main body having the connection being formed by single stage or multistage forging, an interior being formed on the main body by chip-removing machining after forging and a connection channel, which intersects with the interior in an intersection region, being formed at the connection by chip-removing machining after forging. The intersection region is deburred by mechanical deburring. An injection system and a method for producing such a component are also described.

Abstract: A fluid distributor for an injection system, in particular a fuel distributor rail for a fuel injection system for mixture-compressing, spark ignition internal combustion engines. The fuel distributor includes a tubular base body, which is preferably processed by a one-stage or multi-stage forging process, a first high-pressure output, a second high-pressure output, a third high-pressure output, and a fourth high-pressure output being provided at the base body. The second high-pressure output is situated offset by a predefined distance compared to the first high-pressure output in a first direction along a longitudinal axis of the tubular base body. The third high-pressure output is situated offset by the predefined distance compared to the second high-pressure output along the longitudinal axis in the first direction, the fourth high-pressure output being situated offset by the predefined distance compared to the third high-pressure output along the longitudinal axis in the first direction.

Abstract: A component (3; 3?) for an injection system (1), in particular a high-pressure line (5) or a fluid distributor (2), including a base body (14; 13), at which a high-pressure input (15; 12) and at least one high-pressure output (16 through 19; 12?) are provided, at least the base body (14; 13) being at least essentially formed from an austenitic or martensitic material. It is provided that the material is developed as a grain-stabilized material.

Abstract: A component, which can be in the form of a fuel line or fuel distributor, is used for a fuel injection system, which is used for injecting fuel or a mixture of fuel and water having a variable water content. The component has a main body on which is provided a high-pressure inlet and at least one high-pressure outlet, the fuel, respectively the mixture being passable from the high-pressure inlet through an inner space of the main body to the least one high-pressure outlet, and an insertion member being configured in the inner space. The insertion member is at least partially made of at least a material having a modulus of compression specified to at least substantially correspond to or be lower than that of the fuel, respectively the mixture and/or lower than 30 GPa.

Abstract: A component, which can be in the form of a fuel line or fuel distributor, is used for a fuel injection system, which is used for injecting fuel or a mixture of fuel and water having a variable water content. The component has a main body on which is provided a high-pressure inlet and at least one high-pressure outlet, the fuel, respectively the mixture being passable from the high-pressure inlet through an inner space of the main body to the least one high-pressure outlet, and an insertion member being configured in the inner space. The insertion member is at least partially made of at least a material having a modulus of compression specified to at least substantially correspond to or be lower than that of the fuel, respectively the mixture and/or lower than 30 GPa.

Abstract: A rotationally symmetrical bellows has a first end ring and a second end ring with a smaller diameter, and multiple folds, which in a relaxed position each have two flanks running in opposite directions with respect to one another while forming a bend. The flanks extend approximately parallel to an axis of rotation of the bellows. The rotationally symmetrical bellows is designed such that in a relaxed position of the bellows, the second end ring is arranged at an axial distance to the first end ring.

Abstract: A vibration damping system for injection systems of motor vehicles includes an actively controllable actuator element, which is situated at a component of the injection system. The actuator element is situated at the component in such a way that, during operation of the injection system a vibration reduction of the injection system is achieved with the aid of an active control of the actuator element.

Abstract: A fuel distributor, for example that is usable as a fuel rail for mixture-compressing spark-ignition internal combustion engines, includes a main body, on which a plurality of high-pressure outlets are provided. The main body includes at least one dividing wall that at least largely separates an inflow region from a damping region within the main body. The main body is made up of at least two profiles that are joined to each other.

Abstract: An installation switching device has a housing and screw connecting clamp with an essentially frame-shaped clamping part having longitudinal faces, narrow faces and broad faces, a head-clamp screw received in a clamping part threaded aperture, and a current rail arranged fixed in the device extending through the frame-shaped clamping part interior, wherein a current rail broad face is oriented, as assembled, parallel to a clamping part broad face facing the head clamping screw, the screw supporting itself, screwed in, on the current rail, wherein consequently, the clamping part is displaceable in its longitudinal direction, parallel to the narrow face, relative to the current rail by further screwing in the head clamping screw so a connecting conductor can be fixedly clamped between the current rail face remote from the screw and the clamping part broad face remote from the screw, the housing having a screw receiving region guiding the screw head.

Abstract: A vibration damping system for injection systems of motor vehicles includes an actively controllable actuator element, which is situated at a component of the injection system. The actuator element is situated at the component in such a way that, during operation of the injection system a vibration reduction of the injection system is achieved with the aid of an active control of the actuator element.