Patents by Inventor Ramesh Ramji

Ramesh Ramji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and systems for microfluidic screening
    Patent number: 11919000
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: March 5, 2024
    Assignee: 1859, Inc.
    Inventors: Devon Cayer, Andrew MacConnell, Pavel Chubukov, Ramesh Ramji, Sean Stromberg
  • CONTIGUITY PARTICLE FORMATION AND METHODS OF USE
    Publication number: 20220333157
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.
    Type: Application
    Filed: May 16, 2022
    Publication date: October 20, 2022
    Inventors: Frank J. Steemers, Ramesh Ramji, Steven Norberg, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20220305492
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: February 11, 2022
    Publication date: September 29, 2022
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20220297125
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: February 3, 2022
    Publication date: September 22, 2022
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20220266250
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: February 11, 2022
    Publication date: August 25, 2022
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20220226825
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: February 3, 2022
    Publication date: July 21, 2022
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • Contiguity particle formation and methods of use
    Patent number: 11359226
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: June 14, 2022
    Assignee: ILLUMINA, INC.
    Inventors: Frank J. Steemers, Ramesh Ramji, Steven Norberg, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20220176374
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: August 20, 2021
    Publication date: June 9, 2022
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20220176375
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 9, 2022
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • Methods and systems for microfluidic screening
    Patent number: 11351543
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: June 7, 2022
    Assignee: 1859, Inc.
    Inventors: Devon Cayer, Andrew MacConnell, Pavel Chubukov, Ramesh Ramji, Sean Stromberg
  • Methods and systems for microfluidic screening
    Patent number: 11351544
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: June 7, 2022
    Assignee: 1859, Inc.
    Inventors: Devon Cayer, Andrew MacConnell, Pavel Chubukov, Ramesh Ramji, Sean Stromberg
  • Methods and systems for microfluidic screening
    Patent number: 11247209
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: February 15, 2022
    Assignee: 1859, Inc.
    Inventors: Devon Cayer, Andrew MacConnell, Pavel Chubukov, Ramesh Ramji, Sean Stromberg
  • MODULATING POLYMER BEADS FOR DNA PROCESSING
    Publication number: 20210332349
    Abstract: Systems, methods, and compositions provided herein relate to preparation of beads encapsulating biomolecules for performing sequential reactions on the biomolecules. Some embodiments include preparation of nucleic acid reactions within the bead, wherein the bead includes pores that allow diffusion of molecules into or out of the beads while retaining other molecules of interest.
    Type: Application
    Filed: July 1, 2021
    Publication date: October 28, 2021
    Inventors: Steven Norberg, Dmitry Pokholok, Ramesh Ramji, Frank Steemers, Fan Zhang
  • Methods and systems for microfluidic screening
    Patent number: 11123735
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: September 21, 2021
    Assignee: 1859, Inc.
    Inventors: Devon Cayer, Andrew MacConnell, Pavel Chubukov, Ramesh Ramji, Sean Stromberg
  • Modulating polymer beads for DNA processing
    Patent number: 11085036
    Abstract: Systems, methods, and compositions provided herein relate to preparation of beads encapsulating biomolecules for performing sequential reactions on the biomolecules. Some embodiments include preparation of nucleic acid reactions within the bead, wherein the bead includes pores that allow diffusion of molecules into or out of the beads while retaining other molecules of interest.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: August 10, 2021
    Assignee: Illumina, Inc.
    Inventors: Steven Norberg, Dmitry Pokholok, Ramesh Ramji, Frank J. Steemers, Fan Zhang
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210106999
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: November 5, 2020
    Publication date: April 15, 2021
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210107000
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: November 5, 2020
    Publication date: April 15, 2021
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210107004
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: November 5, 2020
    Publication date: April 15, 2021
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210107002
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: November 5, 2020
    Publication date: April 15, 2021
    Inventors: Devon Cayer, Andrew Macconnell, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210106996
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: October 9, 2020
    Publication date: April 15, 2021
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG