Patents by Inventor Ramesh Ramji

Ramesh Ramji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210107003
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: November 5, 2020
    Publication date: April 15, 2021
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210106998
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: November 5, 2020
    Publication date: April 15, 2021
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
    Publication number: 20210107001
    Abstract: Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.
    Type: Application
    Filed: November 5, 2020
    Publication date: April 15, 2021
    Inventors: Devon CAYER, Andrew MACCONNELL, Pavel CHUBUKOV, Ramesh RAMJI, Sean STROMBERG
  • MODULATING POLYMER BEADS FOR DNA PROCESSING
    Publication number: 20200131502
    Abstract: Systems, methods, and compositions provided herein relate to preparation of beads encapsulating biomolecules for performing sequential reactions on the biomolecules. Some embodiments include preparation of nucleic acid reactions within the bead, wherein the bead includes pores that allow diffusion of molecules into or out of the beads while retaining other molecules of interest.
    Type: Application
    Filed: October 24, 2019
    Publication date: April 30, 2020
    Inventors: Steven Norberg, Dmitry Pokholok, Ramesh Ramji, Frank J. Steemers, Fan Zhang
  • CONTIGUITY PARTICLE FORMATION AND METHODS OF USE
    Publication number: 20190352591
    Abstract: Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.
    Type: Application
    Filed: April 15, 2019
    Publication date: November 21, 2019
    Inventors: Frank J. Steemers, Ramesh Ramji, Steven Norberg, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang
  • ANALYSIS SYSTEM FOR ORTHOGONAL ACCESS TO AND TAGGING OF BIOMOLECULES IN CELLULAR COMPARTMENTS
    Publication number: 20190323003
    Abstract: The invention relates to a system and methods for enhancing access to nuclear informational molecules, such as DNA, RNA, and proteins, by analytical biomolecules, such as transposome complexes, by treating nuclei with a nuclear permeability enhancer, and to methods of using nuclear membrane, cell membrane, and external compartmentalization approaches as contiguity preserving elements.
    Type: Application
    Filed: June 28, 2019
    Publication date: October 24, 2019
    Applicant: ILLUMINA, INC.
    Inventors: Ramesh Ramji, Frank J. Steemers, Lena Christiansen, Dmitry K. Pokholok, Fan Zhang
  • Assay device
    Patent number: 10234451
    Abstract: The disclosure relates to a method and device for detecting and quantifying biological molecules such as cell surface or intracellular ligands/receptors in a dynamic system with high sensitivity and specificity; the method of using such platform optionally in combination with an optical detection system and kits comprising the optical platform.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: March 19, 2019
    Assignee: National University of Singapore
    Inventors: Ramesh Ramji, Fook Chiong Cheong, Chwee Teck Lim
  • Simple, Fast and Plasma-Free Method of Fabricating PDMS Microstructures on Glass by Pop Slide Pattering
    Publication number: 20160124205
    Abstract: The present invention relates to patterned microstructures on substrates and methods of making the same. The method completely eliminates the need for elements such as transfer membranes, UV lamps, plasma cleaners, reactive ion etchers, and mask aligners.
    Type: Application
    Filed: October 27, 2015
    Publication date: May 5, 2016
    Inventors: Ramesh Ramji, Kathryn Miller-Jensen, Nafeesa T. Khan
  • ASSAY DEVICE
    Publication number: 20160069874
    Abstract: The disclosure relates to a method and device for detecting and quantifying biological molecules such as cell surface or intracellular ligands/receptors in a dynamic system with high sensitivity and specificity; the method of using such platform optionally in combination with an optical detection system and kits comprising the optical platform.
    Type: Application
    Filed: September 4, 2015
    Publication date: March 10, 2016
    Applicant: National University of Singapore
    Inventors: Ramesh Ramji, Fook Chiong Cheong, Chwee Teck Lim