Patents by Inventor Rangarajan Sampath

Rangarajan Sampath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR USE IN IDENTIFICATION OF NEISSERIA, CHLAMYDIA, AND/OR CHLAMYDOPHILA BACTERIA
    Publication number: 20110183346
    Abstract: The present invention relates generally to the detection and identification of Neisseria, Chlamydia, and/or Chlamydophila bacterial bioagents, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Applicant: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Rachael Kreft, Javier P. Femandez, Lawrence B. Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF CLOSTRIDIUM DIFFICILE
    Publication number: 20110183344
    Abstract: The present invention relates generally to identification of strains of Clostridium difficile and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Inventors: Rangarajan Sampath, Feng Li, David J. Ecker, Robert J. Lovari, Lawrence B. Blyn, Thomas A. Hall
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF STREPTOCOCCUS PNEUMONIAE
    Publication number: 20110183345
    Abstract: The present invention relates generally to the identification of Streptococcus pneumoniae, such as antibiotic resistant Streptococcus pneumoniae, and provides methods, compositions, kits and systems useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Applicant: Ibis Biosciences, Inc.
    Inventors: Christian Massire, Rachael Kreft, Lawrence B. Blyn, David J. Ecker, Feng Li, Rangarajan Sampath
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF MEMBERS OF THE BACTERIAL CLASS ALPHAPROTEOBACTER
    Publication number: 20110183343
    Abstract: The present invention relates generally to identification of members of the bacterial class Alphaproteobacter and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 28, 2011
    Inventors: Rangarajan Sampath, Feng Li, Robert J. Lovari, Lawrence B. Blyn, David J. Ecker
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF FRANCISELLA
    Publication number: 20110177515
    Abstract: The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of bacteria which are members of the Francisella genus by amplification of a segment of bacterial nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: May 29, 2009
    Publication date: July 21, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, David J. Ecker, Mark W. Eshoo, David D. Duncan, Feng Li
  • Secondary Structure Defining Database And Methods For Determining Identity And Geographic Origin Of An Unknown Bioagent Thereby
    Publication number: 20110172925
    Abstract: The present invention relates generally to the field of investigational bioinformatics and more particularly to secondary structure defining databases. The present invention further relates to methods for interrogating a database as a source of molecular masses of known bioagents for comparing against the molecular mass of an unknown or selected bioagent to determine either the identity of the selected bioagent, and/or to determine the origin of the selected bioagent. The identification of the bioagent is important for determining a proper course of treatment and/or irradication of the bioagent in such cases as biological warfare. Furthermore, the determination of the geographic origin of a selected bioagent will facilitate the identification of potential criminal identity.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 14, 2011
    Applicant: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF STRAINS OF E. COLI O157:H7
    Publication number: 20110166040
    Abstract: The present invention relates generally to strain typing of Escherichia coli O157:H7, and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: May 28, 2009
    Publication date: July 7, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: James C. Hannis, Feng Li, Rangarajan Sampath, Lawrence B. Blyn, Steven A. Hofstadler, David J. Ecker, Mark W. Eshoo
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF ADVENTITIOUS VIRUSES
    Publication number: 20110151437
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of adventitious contaminant viruses by molecular mass and base composition analysis.
    Type: Application
    Filed: June 1, 2009
    Publication date: June 23, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, Feng Li, Rachael Kreft, Thomas A. Hall, Lawrence B. Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF TICK-BORNE PATHOGENS
    Publication number: 20110143358
    Abstract: The present invention relates generally to the field of genetic identification and quantification of tick borne pathogens and provides methods, compositions and kits useful for this purpose when combined with molecular mass or base composition analysis.
    Type: Application
    Filed: May 29, 2009
    Publication date: June 16, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, David J. Ecker, Mark W. Eshoo, Heather E. Matthews, Christopher D. Crowder, Lawrence B. Blyn
  • Compositions for use in identification of bacteria
    Patent number: 7956175
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: June 7, 2011
    Assignee: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Thomas A. Hall, David J. Ecker, Lawrence Blyn
  • COMPOSITIONS AND METHODS FOR IDENTIFICATION OF SUBSPECIES CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS
    Publication number: 20110105531
    Abstract: The present invention provides compositions, kits and methods for rapid genotyping of strains of Mycobacterium tuberculosis by molecular mass and base composition analysis. Drug-resistant strains of Mycobacterium tuberculosis may be identified in human clinical samples and as such, provide for methods of treatment of humans infected with drug resistant strains of Mycobacterium tuberculosis.
    Type: Application
    Filed: June 23, 2008
    Publication date: May 5, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Christian Massire, Rangarajan Sampath, Lawrence B. Blyn, David J. Ecker
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF PICORNAVIRUSES
    Publication number: 20110097704
    Abstract: The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses which are members of the Picornaviridae family by amplification of a segment of viral nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: January 27, 2009
    Publication date: April 28, 2011
    Applicant: IBIS Biosciences, Inc.
    Inventors: Rangarajan Sampath, Lawrence B. Blyn
  • Compositions For Use In Genotyping Of Klebsiella Pneumoniae
    Publication number: 20110065111
    Abstract: The present invention relates generally to identification and characterization of genotypes of Klebsiella pneumoniae and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
    Type: Application
    Filed: August 27, 2010
    Publication date: March 17, 2011
    Applicant: Ibis Biosciences, Inc.
    Inventors: Rangarajan Sampath, Feng Li, Lawrence B. Blyn
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF ADVENTITIOUS CONTAMINANT VIRUSES
    Publication number: 20110045456
    Abstract: The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses by amplification of a segment of viral nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: June 12, 2008
    Publication date: February 24, 2011
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, Thomas A. Hall
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF STRAINS OF HEPATITIS C VIRUS
    Publication number: 20100291544
    Abstract: The present invention provides compositions, kits and methods for rapid identification and quantification of strains of hepatitis C viruses by molecular mass and base composition analysis.
    Type: Application
    Filed: May 27, 2008
    Publication date: November 18, 2010
    Applicant: IBIS BIOSCIENCES, INC.
    Inventors: Rangarajan Sampath, Lawrence B. Blyn, Christian Massire
  • Compositions for use in identification of influenza viruses
    Publication number: 20100248219
    Abstract: The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses which are members of the influenza virus family by amplification of a segment of viral nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: October 17, 2006
    Publication date: September 30, 2010
    Inventors: Rangarajan Sampath, Thomas A. Hall, Mark W. Eshoo, Feng Li
  • Methods for rapid identification of pathogens in humans and animals
    Patent number: 7781162
    Abstract: The present invention provides methods of: identifying pathogens in biological samples from humans and animals, resolving a plurality of etiologic agents present in samples obtained from humans and animals, determining detailed genetic information about such pathogens or etiologic agents, and rapid detection and identification of bioagents from environmental, clinical or other samples.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: August 24, 2010
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke
  • COMPOSITIONS FOR USE IN IDENTIFICATION OF MIXED POPULATIONS OF BIOAGENTS
    Publication number: 20100204266
    Abstract: The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of bacterial bioagents and populations of bioagents which are members of the Staphylococcus bacterial genus by amplification of a segment of bioagent nucleic acid followed by molecular mass analysis.
    Type: Application
    Filed: March 21, 2008
    Publication date: August 12, 2010
    Applicant: Ibis Biosciences, INC
    Inventors: David J. Ecker, Rangarajan Sampath, Christian Massire
  • Method for rapid detection and identification of bioagents
    Patent number: 7741036
    Abstract: Method for detecting and identifying unknown bioagents, including bacteria, viruses and the like, by a combination of nucleic acid amplification and molecular weight determination using primers which hybridize to conserved sequence regions of nucleic acids derived from a bioagent and which bracket variable sequence regions that uniquely identify the bioagent. The result is a “base composition signature” (BCS) which is then matched against a database of base composition signatures, by which the bioagent is identified.
    Type: Grant
    Filed: January 13, 2006
    Date of Patent: June 22, 2010
    Assignee: Ibis Biosciences, Inc.
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven Hofstadler, John McNeil
  • Systems for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
    Publication number: 20100145626
    Abstract: The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.
    Type: Application
    Filed: October 26, 2009
    Publication date: June 10, 2010
    Inventors: David J. Ecker, Richard H. Griffey, Rangarajan Sampath, Steven A. Hofstadler, John McNeil, Stanley T. Crooke, Lawrence B. Blyn, Thomas A. Hall, Yun Jiang, James C. Hannis, Neill White, Vivek Samant, Mark W. Eshoo, Jared J. Drader