Abstract: Novel isohexide esters and isohexide compositions are prepared and used in improving skin health and condition.

Abstract: Novel isohexide esters and isohexide compositions are prepared and used in improving skin health and condition.

Abstract: The present invention relates to compositions and methods for treating and/or preventing chronic- or UV-induced photodamage in the skin as well as damage to the skin caused by chronological aging and disease. Specifically, select aryl alkanones have been found to induce/produce a number of beneficial effects in the skin and skin processes by elevating the skin's defense against UV-induced damage and reversing skin photo- and/or chronological damage in the extracellular matrix (ECM) and dermal-epidermal junction (DEJ), up-regulating tissue inhibitory metalloproteases, reducing oxidative stress, inhibiting activity of matrix metalloproteases, and protecting DNA.

Abstract: Compositions and methods for effecting skin lightening and/or even toning involving the use of select aryl alkanones.

Abstract: Compositions and methods based on isosorbide esters for the treatment of multiple sclerosis.

Abstract: The present invention is directed to the hair care treatment compositions, including pre- and post-treatment compositions, containing select aryl alkanone compounds as quenching and/or chelating agents.

Abstract: The present invention relates to compositions and methods for treating and/or preventing chronic- or UV-induced photodamage in the skin as well as damage to the skin caused by chronological aging and disease. Specifically, select aryl alkanones have been found to induce/produce a number of beneficial effects in the skin and skin processes by elevating the skin's defense against UV-induced damage and reversing skin photo- and/or chronological damage in the extracellular matrix (ECM) and dermal-epidermal junction (DEJ), up-regulating tissue inhibitory metalloproteases, reducing oxidative stress, inhibiting activity of matrix metalloproteases, and protecting DNA.

Abstract: Novel isohexides and pharmaceutical compositions containing the same as well as methods of using the same in the treatment of psoriasis.

Abstract: Novel isohexide esters and isohexide compositions are prepared and used in improving skin health and condition.

Abstract: Novel isohexides and pharmaceutical compositions containing the same as well as methods of using the same in the treatment of psoriasis.

Abstract: The present invention relates to hair care compositions comprising select benzylidene 2,4-pentanedione compounds and methods for reducing hair damage, especially oxidative hair damage, arising from various hair treatments. In particular, the compositions according to the present teachings contribute to a reduction or lessening in oxidative damage sustained by hair fibers during bleaching, repeated shampooing, dyeing, perming, straightening and other oxidative treatments. The compositions according to the present invention also provide excellent color evenness, sustained color protection, and reduce scalp itching.

Abstract: The present invention relates to a method for treating, preventing and improving the condition and/or aesthetic appearance of aging skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, through meroterpene induced gene manipulation.

Abstract: Benzylidene substituted 2,4-pentanedione compounds without having phenolic hydroxyl group(s) are found to provide photostability to otherwise photosensitive compounds and compositions.

Abstract: Sunscreen compositions are provided for protecting skin from sun-induced damage comprising (i) at least one UV-B and/or UV-A/UV-B sunblock active, (ii) at least one meroterpene and (iii) a dermatological acceptable carrier wherein the meroterpene is free or substantially free of psoralens and has a purity of at least 90% w/w. Preferably, the sunblock active will be a UV-A/UV-B sunblock active. These skin protective compositions may optionally include an effective amount of one or more skin protective ingredients such as antioxidants, vitamins, anti-inflammatory agents, self-tanning agents and mixtures thereof.

Abstract: Skin conditioning compositions comprising a C4 to C30 monoalkyl-, dialkyl, monoalkanoyl- or dialkanoyl-substituted isohexide are found to exhibit a marked effect on skin hydration and barrier function homeostasis thereby improving skin appearances.

Abstract: Substituted benzylidene 2,4-pentanediones are found to provide stabilization to otherwise photosensitive compounds and compositions.

Abstract: Substituted benzylidene 2,4-pentanediones are found to provide stabilization to otherwise photosensitive compounds and compositions.

Abstract: Benzylidene substituted 2,4-pentanedione compounds without having phenolic hydroxyl group(s) are found to provide photostability to otherwise photosensitive compounds and compositions.

Abstract: Sunscreen compositions are provided for protecting skin from sun-induced damage comprising (i) at least one UV-B and/or UV-A/UV-B sunblock active, (ii) at least one meroterpene and (iii) a dermatological acceptable carrier wherein the meroterpene is free or substantially free of psoralens and has a purity of at least 90% w/w. Preferably, the sunblock active will be a UV-A/UV-B sunblock active. These skin protective compositions may optionally include an effective amount of one or more skin protective ingredients such as antioxidants, vitamins, anti-inflammatory agents, self-tanning agents and mixtures thereof.

Abstract: Skin conditioning compositions comprising a C4 to C30 monoalkyl-, dialkyl, monoalkanoyl- or dialkanoyl-substituted isohexide are found to exhibit a marked effect on skin hydration and barrier function homeostasis thereby improving skin appearances.