Patents by Inventor Raymond A. Firestone

Raymond A. Firestone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acylimine cephalosporins
    Patent number: 4041029
    Abstract: A process is provided which yields derivatives of cephalosporins and penicillins. The process starts with 7-acylaminocephalosporin, or 6-acylaminopenicillin, then the latter compounds are treated with an organolithium compound, followed with t-butyl-hypochlorite. Finally, a defined reagent is added yielding a side chain on the carbon adjacent to the amino-nitrogen. Novel intermediate compounds are also described. The end compounds prepared are active against both gram-positive and gram-negative bacteria.
    Type: Grant
    Filed: September 23, 1975
    Date of Patent: August 9, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Raymond A. Firestone, Lovji D. Cama, Burton G. Christensen
  • C-3 Substituted cephalosporins
    Patent number: 3979384
    Abstract: This invention relates to novel organic compounds and to methods for preparing them. More particularly, this invention provides new and useful cephalosporin compounds which are active antibiotics against both gram-positive and gram-negative microorganisms and compounds which are useful intermediates in the preparation of other new cephalosporin compounds.
    Type: Grant
    Filed: March 20, 1975
    Date of Patent: September 7, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Raymond A. Firestone, John L. Fahey, Burton G. Christensen