Abstract: A method for corrections of measurements of points of interests measured by beams of radiation propagating through stratified media including performance of ray-tracing of at least one ray lunched from a metrology instrument in a direction of an apparent point of interest, calculation a path length of the ray through stratified medium, and determination of coordinates of true position of the point interest using the at least one path length and the direction of propagation of the ray.

Abstract: A method of forming a waveguide, the method comprising the steps of: forming a multilayer stack of light guiding layers; and delaminating the multilayer stack between at least two of the light guiding layers to form a waveguide between the light guiding layers; in which the patterned region has converging sides and the waveguide is tapered, the multilayer stack having increased transmissivity at a region corresponding to a selected thickness of the waveguide. A tapered waveguide is also disclosed, comprising: a multilayer stack of light guiding layers; the multilayer stack defining a channel between at least a first waveguiding layer and a second waveguiding layer; the channel having a diminishing thickness in a first direction; and at least one of the first waveguiding layer and the second waveguiding layer having a region of increased transmissivity adjacent a selected thickness of the core. Methods for the use of the tapered waveguide as an optical coupler or spectrometer are also disclosed.

Abstract: In one embodiment, a variable surface landing platform (VARSLAP) includes a base for contacting a landing surface; at least 3 adjustable struts interconnected with the base, wherein each strut is bisected by a strut actuator-housing, and wherein the at least 3 adjustable struts are interconnected to a main body aerospace craft (MAC); a sensor array on the base; and an attitude determination and control system (ADCS).

Abstract: A unique process for producing electricity from ammonia by utilizing its hydrogen content as a fuel source. The system may be referred to herein for descriptive purposes as Ammonia/Hydrogen/Electricity Production, or AHEP. The novelty of the system disclosed herein as compared to other hydrogen based fuel systems is the unique assembly of the components outlined below to create a novel process and ability to produce electricity that can be utilized for both mobile and stationary purposes. Further, the system is capable of producing hydrogen on demand to be converted into electricity, thereby obviating the need for storing large amounts of explosive hydrogen.

Abstract: An air maintenance tire and connector system includes a tire carcass having an elongate integral air passageway contained within a flexible tire component of the tire carcass between an air inlet and an air outlet cavity and a connector assembly inserted within an outlet one of the cavities. The connector assembly includes a hollow right angled elbow-shaped body fitting within the outlet cavity. The elbow-shaped body's second housing segment has an axial length sufficient to project axially inward from the first housing segment through a tire wall thickness to a tire central cavity. A valve device attaches to a remote end of the second housing segment within the tire cavity, the valve device operative to regulate air flow between the elbow-shaped body central chamber and the tire cavity.

Abstract: The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies may be characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.

Abstract: A direct orientation vector rotor (DOVER) for use on rotary wing aircraft includes a gear set for multidirectional rotor orientation based on the spherical coordinate system; an inclination mechanism, wherein the rotor is moved from the 0° horizontal position to an inclined position; a rotational turret, wherein the rotor is moved along the azimuth and wherein the inclination mechanism is housed; and a motion-adapted gear lubrication housing.

Abstract: A pneumatic tire assembly includes a pneumatic tire having an inner cavity and an inner surface at least partially defining the inner cavity, a rigid structure for facilitating operation of the tire assembly, and a docking base for securing the rigid structure to the inner surface of the inner cavity. The docking base has been integrally bonded to the inner surface during curing of the pneumatic tire. The docking base has a shape formed by a mold attached to the inner surface of the inner cavity during curing of the pneumatic tire. The mold subsequently is removed thereby resulting in the docking base integrally secured to the inner surface.

Abstract: An air-maintenance tire system includes a compression actuator mounted to the tire carcass configured for operative actuation by tire deformation during a tire revolution, a pump assembly affixed to the tire carcass and including a compressor body affixed to the compression actuator and having an internal air chamber, the air chamber having an inlet opening for admitting air into the internal air chamber and an outlet opening for conducting air from the internal air chamber to the tire cavity. The air compressor body further includes a piston valve member and an outlet valve member located within and at opposite respective ends of the internal air chamber, the piston valve member and the outlet valve member moving within the internal air chamber responsive to actuation by the compression actuator between respective open and closed positions, whereby cyclically opening and closing the inlet and the outlet openings during an air compression cycle.

Abstract: A data collector associated with a grain bin is in communication with a plurality of capacitive moisture cables hanging within the grain bin. Each capacitive moisture cable includes a plurality of sensor nodes positioned along the moisture cable. Each sensor node includes a sensor node microprocessor and a sensor node memory coupled to a temperature sensor, a reference capacitive sensor and a capacitive moisture sensor. A main controller is in communication with the data collector. The main controller memory is configured in a data structure comprising grain type data, temperature data, raw reference capacitance data, raw moisture capacitance data, node identification data, physical node positional data, and a calculated moisture content for each sensor node. A method of determining moisture contents of grain in a grain bin related to such a system is also included.

Abstract: Each grain bin includes a data collector coupled to multiple capacitive moisture cables, each with multiple sensor nodes spaced along it. Each sensor node includes a pair of longitudinally extending capacitive plates of the capacitive moisture sensor positioned in side-by-side, spaced-apart relationship to form a longitudinally extending gap between the capacitive plates. Positioned within the longitudinal gap between the capacitive plates is a circuit board including a microprocessor, memory, and temperature sensor. An outer housing provides a sealed enclosure that surrounds the circuit board, the capacitive plates, and a longitudinal length of the moisture cable that extends through and seals openings in each longitudinal end of the housing.

Abstract: The present application relates novel HIV-1 broadly neutralizing antibodies. The antibodies of the present invention are further characterized by their ability to bind epitopes from the Env proteins. The invention also provides light and heavy chain variable region sequences. Compositions for prophylaxis, diagnosis and treatment of HIV infection are provided.

Abstract: A method of forming a waveguide is disclosed, as well as the waveguide itself. A multilayer stack of light guiding layers is formed, and the multilayer stack is delaminated between light guiding layers to form a waveguide between the light guiding layers. The multilayer stack is delaminated in a patterned region between light guiding layers. Here a new approach is described, wherein hollow microchannels forming a Bragg waveguide assembly are fabricated by controlled formation of thin film delamination buckles within a multilayer stack. A hollow waveguide is formed by alternating layers of the multilayer stack forming light guiding surfaces. The hollow waveguide is formed between layers that delaminate from each other, as for example under applied stress to one or more of the layers. The multi-layer stack may be formed of alternating layers of low and high index of refraction materials, as for example forming omni-directional dielectric reflectors.

Abstract: An air maintenance tire and connector system includes a tire carcass having an elongate integral air passageway contained within a flexible tire component of the tire carcass between an air inlet and an air outlet cavity and a connector assembly inserted within an outlet one of the cavities. The connector assembly includes a hollow right angled elbow-shaped body fitting within the outlet cavity. The elbow-shaped body's second housing segment has an axial length sufficient to project axially inward from the first housing segment through a tire wall thickness to a tire central cavity. A valve device attaches to a remote end of the second housing segment within the tire cavity, the valve device operative to regulate air flow between the elbow-shaped body central chamber and the tire cavity.

Abstract: A method of constructing a tire includes: constructing an elongate strip core; encasing the strip core into a containment within an uncured flexible tire component, the strip core extending between an air inlet and an air outlet cavity in the flexible tire component; building on a tire building drum a green tire carcass from tire components including the flexible tire component and encased strip core; removing the encased strip core from the cured flexible tire component to leave within the flexible tire component a substantially unobstructed air passageway; and inserting a permanent air inlet assembly into the air inlet cavity and a permanent air outlet assembly into the air outlet cavity.

Abstract: In one embodiment, a variable surface landing platform (VARSLAP) includes a base for contacting a landing surface; at least 3 adjustable struts interconnected with the base, wherein each strut is bisected by a strut actuator-housing, and wherein the at least 3 adjustable struts are interconnected to a main body aerospace craft (MAC); a sensor array on the base; and an attitude determination and control system (ADCS).

Abstract: The present invention relates to a double-stranded siRNA molecule that is capable of silencing gene expression as well as inducing an immune response. The molecule comprises a sense strand and an antisense strand, wherein the antisense strand comprises a first nucleotide sequence that is specifically complementary to mRNA transcribed from a target gene, and the sense strand comprises a second nucleotide sequence that is substantially or perfectly complementary to the antisense strand with the exception that the second nucleotide sequence comprises at least one immunostimulatory motif comprising two or more non-complementary nucleotides. Such a molecule may be utilized in a method of treating or preventing a disease or condition (such as a viral infection, a bacterial infection, or cancer) in a subject.

Abstract: An air-maintenance tire system includes a compression actuator mounted to the tire carcass configured for operative actuation by tire deformation during a tire revolution, a pump assembly affixed to the tire carcass and including a compressor body affixed to the compression actuator and having an internal air chamber, the air chamber having an inlet opening for admitting air into the internal air chamber and an outlet opening for conducting air from the internal air chamber to the tire cavity. The air compressor body further includes a piston valve member and an outlet valve member located within and at opposite respective ends of the internal air chamber, the piston valve member and the outlet valve member moving within the internal air chamber responsive to actuation by the compression actuator between respective open and closed positions, whereby cyclically opening and closing the inlet and the outlet openings during an air compression cycle.

Abstract: A thin film transistor (TFT) array having test circuitry includes a thin film transistor array body having a plurality of pixels. Test circuitry is integrally formed with the body. The test circuitry includes a power supply for supplying power via the test circuitry to the body; and a plurality of wireless switches to activate selected pixels.

Abstract: A power converter includes a power train with a coupled inductor and a plurality of regulators, and method of forming and operating the same. In one embodiment, the power train includes a coupled inductor including a magnetic core with a common leg, a first leg and a second leg. The coupled inductor also includes a common winding formed around the common leg, and first and second windings. The first winding is formed around the first leg, and is electrically and magnetically coupled to the common winding. The second winding is formed around the second leg, and is electrically and magnetically coupled to the common winding. The power train also includes a first regulator including a first main switch coupled to the first winding and a second regulator including a second main switch coupled to the second winding.