Patents by Inventor Raymond P. Goodrich

Raymond P. Goodrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9044523
    Abstract: Methods and apparatuses are provided for reduction of pathogens in fluids containing blood products. Preferred methods include the steps of adding an effective, non-toxic amount of a photosensitizer such as riboflavin to the blood product and exposing the fluid to light having a peak wavelength.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: June 2, 2015
    Assignee: TERUMO BCT, INC.
    Inventors: Dennis J. Hlavinka, Raymond P. Goodrich, Heather Reddy
  • Patent number: 8759092
    Abstract: Methods are provided for treating a vaccine containing infectious particles which may be viral, bacterial, and/or cellular in nature. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to the fluid and exposing the fluid to photoradiation sufficient to inactivate the infectious particles but not enough to damage the antigenic characteristics of the infectious particles.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: June 24, 2014
    Assignee: Terumo BCT Biotechnologies, LLC
    Inventor: Raymond P. Goodrich
  • Patent number: 8679736
    Abstract: The methods of this invention involve preventing the formation of a complex between adenine and riboflavin by reducing the amount of adenine in a solution containing blood or blood components to be pathogen reduced.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: March 25, 2014
    Assignee: Terumo BCT Biotechnologies, LLC
    Inventors: Raymond P. Goodrich, Suzann K. Doane
  • Publication number: 20110306617
    Abstract: Methods are provided for preparation of compositions having an enhanced level of soluble alloxazine, as compared to compositions prepared using conventional techniques. Compositions and a riboflavin form having higher solubility in solution is also provided.
    Type: Application
    Filed: August 24, 2011
    Publication date: December 15, 2011
    Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLC
    Inventors: Eric T. HANSEN, Raymond P. GOODRICH
  • Patent number: 8044051
    Abstract: Methods are provided for preparation of compositions having an enhanced level of soluble alloxazine, as compared to compositions prepared using conventional techniques. Compositions and a riboflavin form having higher solubility in solution is also provided.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: October 25, 2011
    Assignee: CaridianBCT Biotechnologies, LLC
    Inventors: Eric T. Hansen, Raymond P. Goodrich
  • Publication number: 20110236876
    Abstract: A process for damaging and maintaining damage to the nucleic acids of pathogens such as white blood cells, bacteria and viruses which may be contained in blood or blood components. This process comprises adding to the blood or blood component containing pathogens an effective amount of riboflavin, and exposing the fluid to light of an appropriate wavelength to damage the nucleic acid of the pathogen and to substantially maintain the damage to the pathogenic nucleic acids to allow for subsequent transfusion into a recipient.
    Type: Application
    Filed: June 8, 2011
    Publication date: September 29, 2011
    Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLC
    Inventors: Robert Owen LOCKERBIE, Vijay KUMAR, Shawn D. KEIL, Raymond P. GOODRICH
  • Patent number: 8017110
    Abstract: A process for damaging and maintaining damage to the nucleic acids of pathogens such as white blood cells, bacteria and viruses which may be contained in blood or blood components. This process comprises adding to the blood or blood component containing pathogens an effective amount of riboflavin, and exposing the fluid to light of an appropriate wavelength to damage the nucleic acid of the pathogen and to substantially maintain the damage to the pathogenic nucleic acids to allow for subsequent transfusion into a recipient.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: September 13, 2011
    Assignee: CaridianBCT Biotechnologies, LLC
    Inventors: Raymond P. Goodrich, Shawn D. Keil, Robert Owen Lockerbie, Vijay Kumar
  • Patent number: 8016736
    Abstract: A method for washing multiple units of blood product including providing a centrifuge having a wash cell for each unit of blood product, balancing the centrifuge to accommodate for differences in the wash cells, and transferring supernatant including any wash solution from each unit of blood product on the centrifuge.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: September 13, 2011
    Assignee: CaridianBCT Biotechnologies, LLC
    Inventors: Dennis J. Hlavinka, Raymond P. Goodrich, Eric T. Hansen
  • Patent number: 7985588
    Abstract: A process for damaging and maintaining damage to the nucleic acids of pathogens such as white blood cells, bacteria and viruses which may be contained in blood or blood components. This process comprises adding to the blood or blood component containing pathogens an effective amount of riboflavin, and exposing the fluid to light of an appropriate wavelength to damage the nucleic acid of the pathogen and to substantially maintain the damage to the pathogenic nucleic acids to allow for subsequent transfusion into a recipient.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: July 26, 2011
    Assignee: CaridianBCT Biotechnologies, LLC
    Inventors: Raymond P. Goodrich, Shawn D. Keil
  • Patent number: 7901673
    Abstract: A process for damaging and maintaining damage to the nucleic acids of pathogens such as white blood cells, bacteria and viruses which may be contained in blood or blood components. This process comprises adding to the blood or blood component containing pathogens an effective amount of riboflavin, and exposing the fluid to light of an appropriate wavelength to damage the nucleic acid of the pathogen and to substantially maintain the damage to the pathogenic nucleic acids to allow for subsequent transfusion into a recipient.
    Type: Grant
    Filed: August 25, 2003
    Date of Patent: March 8, 2011
    Assignee: CaridianBCT Biotechnologies, LLC
    Inventors: Robert Owen Lockerbie, Vijay Kumar, Shawn D. Keil, Raymond P. Goodrich
  • Patent number: 7892535
    Abstract: This invention is directed toward a process for reducing transfusion related complications in a recipient of an allogeneic blood transfusion by adding to the blood to be transfused a photosensitizer comprising riboflavin, irradiating the blood and riboflavin with light, transfusing the irradiated blood into a recipient, and reducing a transfusion related complication by the recipient to cells in the donor blood. The invention is also directed towards a process for preventing rejection of a donor organ by a recipient comprising the steps of transfusing the recipient of the donor organ with treated platelets; and transplanting the donor organ into the recipient.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: February 22, 2011
    Assignee: CaridianBCT Biotechnologies, LLC
    Inventors: Raymond P. Goodrich, Junzhi Li
  • Publication number: 20110014239
    Abstract: Methods are provided for treating a vaccine containing infectious particles which may be viral, bacterial, and/or cellular in nature. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to the fluid and exposing the fluid to photoradiation sufficient to inactivate the infectious particles but not enough to damage the antigenic characteristics of the infectious particles.
    Type: Application
    Filed: August 26, 2010
    Publication date: January 20, 2011
    Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLC
    Inventor: Raymond P. GOODRICH
  • Publication number: 20100089840
    Abstract: The methods of this invention involve preventing the formation of a complex between adenine and riboflavin by reducing the amount of adenine in a solution containing blood or blood components to be pathogen reduced.
    Type: Application
    Filed: December 17, 2009
    Publication date: April 15, 2010
    Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLC
    Inventors: Raymond P. GOODRICH, Suzann K. DOANE
  • Publication number: 20100080781
    Abstract: This invention is directed toward a process for reducing transfusion related complications in a recipient of an allogeneic blood transfusion by adding to the blood to be transfused a photosensitizer comprising riboflavin, irradiating the blood and riboflavin with light, transfusing the irradiated blood into a recipient, and reducing a transfusion related complication by the recipient to cells in the donor blood. The invention is also directed towards a process for preventing rejection of a donor organ by a recipient comprising the steps of transfusing the recipient of the donor organ with treated platelets; and transplanting the donor organ into the recipient.
    Type: Application
    Filed: December 3, 2009
    Publication date: April 1, 2010
    Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLC
    Inventors: Raymond P. GOODRICH, Junzhi LI
  • Patent number: 7648699
    Abstract: This invention is directed toward a process for reducing transfusion related complications in a recipient of an allogeneic blood transfusion by adding to the blood to be transfused a photosensitizer comprising riboflavin, irradiating the blood and riboflavin with light, transfusing the irradiated blood into a recipient, and reducing a transfusion related complication by the recipient to cells in the donor blood. The invention is also directed towards a process for preventing rejection of a donor organ by a recipient comprising the steps of transfusing the recipient of the donor organ with treated platelets; and transplanting the donor organ into the recipient.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: January 19, 2010
    Assignee: CaridianBCT Biotechnologies, LLC
    Inventors: Raymond P. Goodrich, Junzhi Li
  • Patent number: 7498156
    Abstract: This invention is directed towards a method of using visible light at wavelengths of at least 500 nm and above in combination with a sensitizer having a flavin moiety to reduce any pathogens that may be contained in blood and blood components. By exposing the blood and blood components to light of 500 nm and higher, only the sensitizer that is bound to nucleic acids of the pathogens will be activated, thus destroying the sensitizer-pathogenic nucleic acid complex. Because unbound sensitizer is not activated at this wavelength, damage to blood and blood components caused by photolysis of unbound sensitizer may be avoided.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: March 3, 2009
    Assignees: CaridianBCT Biotechnologies, LLC, Ohio State University Research Foundation
    Inventors: Raymond P. Goodrich, Matthew S. Platz, Christopher B. Martin
  • Publication number: 20090023130
    Abstract: This invention is directed toward a method of preventing the formation of bioactive substances in a pathogen inactivated blood component. The steps include illuminating the blood component with light at a sufficient energy so that an alloxazine photosensitizer present in the blood component may be photolyzed to inactivate any pathogens which may be present; preventing the formation of bioactive substances in the pathogen inactivated blood component; and storing the pathogen inactivated blood component.
    Type: Application
    Filed: August 13, 2008
    Publication date: January 22, 2009
    Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLC
    Inventors: Raymond P. GOODRICH, Suzanne MARSCHNER
  • Publication number: 20080299538
    Abstract: This invention is directed toward a method of pathogen inactivating whole blood. The steps include collecting whole blood from a donor into a bag; illuminating the whole blood with light at a sufficient energy so that an alloxazine photosensitizer present in the whole blood may be photolyzed to inactivate any pathogens which may be present in the whole blood; and storing the pathogen inactivated whole blood. The invention also includes a method of separating the pathogen inactivated whole blood into components.
    Type: Application
    Filed: July 30, 2008
    Publication date: December 4, 2008
    Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLC
    Inventors: Raymond P. GOODRICH, Dennis J. HLAVINKA, Heather L. REDDY
  • Publication number: 20080176208
    Abstract: Methods and apparatuses are provided for reduction of pathogens in fluids containing blood products. Preferred methods include the steps of adding an effective, non-toxic amount of a photosensitizer such as riboflavin to the blood product and exposing the fluid to light having a peak wavelength.
    Type: Application
    Filed: August 17, 2007
    Publication date: July 24, 2008
    Applicant: NAVIGANT BIOTECHNOLOGIES, LLC
    Inventors: Dennis J. HLAVINKA, Raymond P. GOODRICH, Heather REDDY
  • Publication number: 20080096750
    Abstract: A method for washing multiple units of blood product including providing a centrifuge having a wash cell for each unit of blood product, balancing the centrifuge to accommodate for differences in the wash cells, and transferring supernatant including any wash solution from each unit of blood product on the centrifuge.
    Type: Application
    Filed: October 19, 2007
    Publication date: April 24, 2008
    Applicant: NAVIGANT BIOTECHNOLOGIES, LLC
    Inventors: Dennis J. HLAVINKA, Raymond P. GOODRICH, Eric T. HANSEN