Patents by Inventor Rebecca Gottlieb
Rebecca Gottlieb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060247603Abstract: A system and method for restenosis mitigation at a trauma site within the vasculature. The system may include a catheter capable of delivering a restenosis mitigating drug and a sensor extending through a lumen in the catheter. The catheter may be positioned adjacent the trauma site and the restenosis mitigating drug may be delivered to the trauma site through the catheter. The restenosis mitigating drug or some other parameter may be sensed by the sensor.Type: ApplicationFiled: June 28, 2006Publication date: November 2, 2006Inventors: Rebecca Gottlieb, Bradley Enegren, Rajiv Shah
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Publication number: 20060076236Abstract: The disclosure provides methods for fabricating a long-term analyte sensor for measuring at least one analyte in the body of a user. The analyte sensors made by these methods include a plurality of analyte contacting sensor elements and at least one structure for relaying information to and from the sensor. The analyte sensor so fabricated further includes at least one sensor protection membrane that is controllable in a manner such that sensor elements may be activated (e.g. exposed to the external environment) at different times so as to extend the useful life of the sensor. In illustrative analyte sensors, the analyte is glucose.Type: ApplicationFiled: January 12, 2005Publication date: April 13, 2006Inventors: Rajiv Shah, Shaun Pendo, Rebecca Gottlieb, Gil Bruso, Gopikrishnan Soundararajan, Katherine Wolfe
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Publication number: 20060025663Abstract: A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.Type: ApplicationFiled: July 27, 2004Publication date: February 2, 2006Inventors: Cary Talbot, John Mastrototaro, Rajiv Shah, Edward Chernoff, John Mueller, Varaz Shahmirian, Richard Purvis, Wayne Morgan, Rebecca Gottlieb
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Patent number: 6991096Abstract: A packaging system for hydrating sterile devices without comprising the integrity of the sterilization. The packaging system may include an enclosure for enclosing a device requiring hydration, a container containing a hydrate, a base located within the interior of the enclosure and an activating member located within the interior of the enclosure. The container and the device may be located within a receptacle. The receptacle may rest on the base and the activating member may be affixed on top of the receptacle. A force may be exerted on an exterior portion of the enclosure such that the activating member pushes on the receptacle and crushes or ruptures the container. The hydrate located within the container is then released to the device, thereby hydrating the device without breaking the seal of the enclosure. The sterilized environment is therefore maintained and the device is hydrated.Type: GrantFiled: December 27, 2002Date of Patent: January 31, 2006Assignee: Medtronic MiniMed, Inc.Inventors: Rebecca Gottlieb, Aaron Swanson, Bahar Reghabi, Kevin Branch
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Publication number: 20060004272Abstract: A long term analyte sensor for measuring at least one analyte in the body of a user and which includes a housing, a plurality of analyte contacting sensor elements and at least one structure for relaying information away from the sensor. This plurality of analyte contacting sensor elements are typically disposed in an array. The analyte sensor further includes at least one sensor protection membrane that is controllable in a manner such that sensor elements may be activated (e.g. exposed to the external environment) at different times so as to extend the useful life of the sensor. In illustrative analyte sensors, the analyte is glucose.Type: ApplicationFiled: November 15, 2004Publication date: January 5, 2006Inventors: Rajiv Shah, Rebecca Gottlieb, Eric Grovender, Shaun Pendo, Paul Citron, William Van Antwerp
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Publication number: 20050272989Abstract: Embodiments of the invention provide analyte sensors having stabilized coating compositions and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having stabilized glucose oxidase coatings.Type: ApplicationFiled: June 4, 2004Publication date: December 8, 2005Applicant: Medtronic MiniMed, Inc.Inventors: Rajiv Shah, Bahar Reghabi, Rebecca Gottlieb, Udo Hoss, John Mastrototaro
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Publication number: 20050223679Abstract: A packaging system for hydrating sterile devices without comprising the integrity of the sterilization. The packaging system may include an enclosure for enclosing a device requiring hydration, a container containing a hydrate, a base located within the interior of the enclosure and an activating member located within the interior of the enclosure. The container and the device may be located within a receptacle. The receptacle may rest on the base and the activating member may be affixed on top of the receptacle. A force may be exerted on an exterior portion of the enclosure such that the activating member pushes on the receptacle and crushes or ruptures the container. The hydrate located within the container is then released to the device, thereby hydrating the device without breaking the seal of the enclosure. The sterilized environment is therefore maintained and the device is hydrated.Type: ApplicationFiled: June 10, 2005Publication date: October 13, 2005Inventors: Rebecca Gottlieb, Aaron Swanson, Bahar Reghabi, Kevin Branch
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Publication number: 20050148832Abstract: An apparatus for sensing multiple parameters includes an implantable housing and a plurality of implantable sensors disposed within the implantable housing. The plurality of implantable sensors sense parameters in a patient, such as biological or physiological parameters, for example, and each responds to an analyte in the patient. The plurality of implantable sensors may include, but is not limited to, electrochemical, potentiometric, current and optical sensors.Type: ApplicationFiled: December 26, 2003Publication date: July 7, 2005Inventors: Bahar Reghabi, Rebecca Gottlieb, Rajiv Shah, Bradley Enegren, William Van Antwerp
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Publication number: 20050065556Abstract: A system and method of sensing multiple parameters. The method may include implanting an implantable sensor in a patient and reading an output from at least one of the implantable sensing elements. The implantable sensor may have a housing within which are disposed a plurality of implantable sensing elements. At least one of the implantable sensing elements may respond to lactate. In addition, a medical professional may administer to the patient for myocardial ischemia, myocardial infarction angina, sepsis based on the output read. A medical professional may also administer to the patient having an implantable cardiovascular defibrillator or who is receiving extracorporeal membrane oxygenation. The method may be used in a surgical or intensive care environment.Type: ApplicationFiled: September 23, 2003Publication date: March 24, 2005Inventors: Bahar Reghabi, Rebecca Gottlieb, Rajiv Shah, Bradley Enegren
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Publication number: 20050049641Abstract: A method and apparatus for enhancing the integrity of an implantable sensor. Voids formed between an outer tubing and a sensor substrate or spacing element may be back-filled with a curable, implantable material, minimizing the extent to which unwanted fluids diffuse within the sensor. An enzyme or protein matrix pellet below the sensor window may be pre-treated with a reducing agent to enhance its bond stability, and to reduce undesired swelling that may cause the sensor window to detach or leak. The bonding between the enzyme pellet and a hydrogel layer may be reinforced by application of an intervening bonding layer of a protein material, such as human serum albumin (HSA). The size of the window may be minimized by minimizing the size of an underlying electrode, providing reduced flux and lengthening sensor. A coating may be deposited on the surface of the sensor leads, providing stiffening and lubrication.Type: ApplicationFiled: August 26, 2004Publication date: March 3, 2005Inventors: Rajiv Shah, Yanan Zhang, Rebecca Gottlieb, Bahar Reghabi, Michael Miller
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Publication number: 20050033263Abstract: A system and method for restenosis mitigation at a trauma site within the vasculature. The system may include a catheter capable of delivering a restenosis mitigating drug and a sensor extending through a lumen in the catheter. The catheter may be positioned adjacent the trauma site and the restenosis mitigating drug may be delivered to the trauma site through the catheter. The restenosis mitigating drug or some other parameter may be sensed by the sensor.Type: ApplicationFiled: August 7, 2003Publication date: February 10, 2005Inventors: Rebecca Gottlieb, Bradley Enegren, Rajiv Shah
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Publication number: 20040143173Abstract: A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing and a resealable insertion site coupled to one end of the site housing. Preferably, the site housing is formed to have an interior cavity, and includes an outer membrane made of a material selected to promote vascularization and having a first pore size, and an inner membrane made of a material selected to be free of tissue ingress. Also, the site housing permits the analyte to pass through the site housing to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site is provided for inserting the replaceable analyte sensor into the interior cavity of the site housing.Type: ApplicationFiled: June 2, 2003Publication date: July 22, 2004Applicant: MEDTRONIC MINIMED, INC.Inventors: Bahar Reghabi, Rajiv Shah, Eunjoo Jin, Rebecca Gottlieb, Michael E. Miller, Nannette M. Van Antwerp, Bradley J. Enegren, William P. Van Antwerp, John J. Mastrototaro
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Publication number: 20040064156Abstract: A method and apparatus for enhancing the integrity of an implantable sensor. Voids formed between an outer tubing and a sensor substrate or spacing element may be back-filled with a curable, implantable material, minimizing the extent to which unwanted fluids diffuse within the sensor. An enzyme or protein matrix pellet below the sensor window may be pre-treated with a reducing agent to enhance its bond stability, and to reduce undesired swelling that may cause the sensor window to detach or leak. The bonding between the enzyme pellet and a hydrogel layer may be reinforced by application of an intervening bonding layer of a protein material, such as human serum albumin (HSA). The size of the window may be minimized by minimizing the size of an underlying electrode, providing reduced flux and lengthening sensor. A coating may be deposited on the surface of the sensor leads, providing stiffening and lubrication.Type: ApplicationFiled: December 31, 2002Publication date: April 1, 2004Applicant: MEDTRONIC MINIMED, INC.Inventors: Rajiv Shah, Yanan Zhang, Rebecca Gottlieb, Bahar Reghabi, Michael E. Miller
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Publication number: 20040060260Abstract: A packaging system for hydrating sterile devices without comprising the integrity of the sterilization. The packaging system may include an enclosure for enclosing a device requiring hydration, a container containing a hydrate, a base located within the interior of the enclosure and an activating member located within the interior of the enclosure. The container and the device may be located within a receptacle. The receptacle may rest on the base and the activating member may be affixed on top of the receptacle. A force may be exerted on an exterior portion of the enclosure such that the activating member pushes on the receptacle and crushes or ruptures the container. The hydrate located within the container is then released to the device, thereby hydrating the device without breaking the seal of the enclosure. The sterilized environment is therefore maintained and the device is hydrated.Type: ApplicationFiled: December 27, 2002Publication date: April 1, 2004Applicant: MEDTRONIC MINIMED, INC.Inventors: Rebecca Gottlieb, Aaron Swanson, Bahar Reghabi, Kevin Branch
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Publication number: 20040064086Abstract: A multilumen catheter having tubings extending into lumens within the catheter. The lumens may be used for blood, drugs or other medicants. The lumens may also be used for sensors. The junction element, external to the patient, connects the tubings to the lumens. The tubings, also external to the patient, connect to infusion members, to which one or more infusion systems may be connected to deliver blood, drugs and other medicants to the patient. A sensor having a sensing element may extend through the sensor lumen and be positioned internal to the patient for physiological parameter sensing. An external portion of the sensor may be connected to associated electronics to provide automatic monitoring of the physiological parameters and automatic delivery and control of the infusants.Type: ApplicationFiled: December 30, 2002Publication date: April 1, 2004Applicant: MEDTRONIC-MINIMEDInventors: Rebecca Gottlieb, Rajiv Shah, Mary M. Morris, Victor Giron, Michael E. Miller, Bradley J. Enegren
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Publication number: 20030220552Abstract: A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing material and a resealable insertion site coupled to one end of the site housing material. Preferably, the site housing material is formed to have an interior cavity with an opening. The site housing material is selected to promote tissue ingrowth and vascularization, and yet be free of tissue ingress. Also, the site housing material permits the analyte to pass through the site housing material to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site provides a for inserting the replaceable analyte sensor into the interior cavity of the site housing material.Type: ApplicationFiled: February 12, 2003Publication date: November 27, 2003Applicant: MEDTRONIC MINIMED, INC.Inventors: Bahar Reghabi, Rajiv Shah, Eunjoo Jin, Rebecca Gottlieb, Michael E. Miller, Nannette M. Van Antwerp, Bradley J. Enegren, William P. Van Antwerp, John J. Mastrototaro