Patents by Inventor Reid W. von Borstel

Reid W. von Borstel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis
    Patent number: 7307166
    Abstract: The invention relates to certain oxypurine nucleosides, congeners of such oxypurine nucleosides, and acyl derivatives thereof, and compositions which contain at least one of these compounds. The invention also relates to methods of treating or preventing hematopoietic disorders and modifying hematopoiesis, and treating or preventing inflammatory diseases and bacterial infections by administering a compound or composition of the present invention to an animal.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 11, 2007
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand, James C. Butler, Shyam Shirali
  • Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis
    Patent number: 7173017
    Abstract: Pyrimidine nucleotide precursors including acyl derivatives of cytidine, uridine, and orotate, and uridine phosphorylase inhibitors, and their use in enhancing resistance to sepsis or systemic inflammation are disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 6, 2007
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand
  • Acyl deoxyribonucleoside derivatives and uses thereof
    Patent number: 7169765
    Abstract: The invention relates to compositions comprising acyl derivatives of 2?-deoxyribonucleosides. The invention also relates to methods of treating or preventing radiation, mutagen and sunlight-induced biological damage, and methods for improving wound healing and tissue repair, comprising administering the compositions of the present invention to an animal.
    Type: Grant
    Filed: January 31, 2000
    Date of Patent: January 30, 2007
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Reid W. Von Borstel, Michael K. Bamat
  • Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides
    Patent number: 7166581
    Abstract: The subject invention discloses compounds, compositions and methods for treatment and prevention of toxicity due to chemotherapeutic agents and antiviral agents. Disclosed are acylated derivatives of non-methylated pyrimidine nucleosides. These compounds are capable of attenuating damage to the hematopoietic system in animals receiving antiviral or antineoplastic chemotherapy.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 23, 2007
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Reid W. von Borstel, Michael K. Bamat
  • Compounds for the treatment of metabolic disorders
    Patent number: 7101910
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: September 5, 2006
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Compounds for the treatment of metabolic disorders
    Patent number: 7012071
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: March 14, 2006
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Compositions and methods for treatment of mitochondrial diseases
    Patent number: 6956028
    Abstract: Compounds, compositions, and methods are provided for treatment of disorders related to mitochondrial dysfunction. The methods comprise administering to a mammal a composition containing pyrimidine nucleotide precursors in amounts sufficient to treat symptoms resulting from mitochondrial respiratory chain deficiencies.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: October 18, 2005
    Assignee: Wellstat Therapeutics Coporation
    Inventor: Reid W. von Borstel
  • Compounds for the treatment of metabolic disorders
    Patent number: 6946491
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: September 20, 2005
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Compounds for the treatment of metabolic disorders
    Patent number: 6924314
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: August 2, 2005
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Compounds for the treatment of metabolic disorders
    Patent number: 6858602
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: February 22, 2005
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Compounds for the treatment of metabolic disorders
    Publication number: 20040242692
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Application
    Filed: June 10, 2004
    Publication date: December 2, 2004
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis
    Publication number: 20040235782
    Abstract: The invention relates to certain oxypurine nucleosides, congeners of such oxypurine nucleosides, and acyl derivatives thereof, and compositions which contain at least one of these compounds. The invention also relates to methods of treating or preventing hematopoietic disorders and modifying hematopoiesis, and treating or preventing inflammatory diseases and bacterial infections by administering a compound or composition of the present invention to an animal.
    Type: Application
    Filed: June 25, 2004
    Publication date: November 25, 2004
    Applicant: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand, James C. Butler, Shyam Shirali
  • Compounds for the treatment of metabolic disorders
    Publication number: 20040236100
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Application
    Filed: October 14, 2003
    Publication date: November 25, 2004
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis
    Publication number: 20040220134
    Abstract: Pyrimidine nucleotide precursors including acyl derivatives of cytidine, uridine, and orotate, and uridine phosphorylase inhibitors, and their use in enhancing resistance to sepsis or systemic inflammation are disclosed.
    Type: Application
    Filed: May 28, 2004
    Publication date: November 4, 2004
    Applicant: Pro-Neuron, Inc.
    Inventors: Reid W. von Borstel, Michael K. Bamat, Bradley M. Hiltbrand
  • Acyl deoxyribonucleoside derivatives and uses thereof
    Publication number: 20040192635
    Abstract: The invention relates to compositions comprising acyl derivatives of 2′-deoxyribonucleosides. The invention also relates to methods of treating or preventing radiation, mutagen and sunlight-induced cellular damage, methods for improving wound healing and tissue repair, and methods for ameliorating the effects of aging comprising administering the compositions of the present invention to an animal.
    Type: Application
    Filed: April 15, 2004
    Publication date: September 30, 2004
    Applicant: Wellstat Therapeutics Corporation
    Inventors: Reid W. Von Borstel, Michael K. Bamat
  • Tobacco smoke filter
    Patent number: 6792953
    Abstract: A tobacco smoke filter a copper-containing porphyrin or an iron analog of C.I. Reactive Blue 21 dye. A method of making a first tobacco smoke filter segment, comprising the steps of, first, providing one or more than one substance; producing a mixture of cellulose fiber and the substance; heating the mixture for a sufficient time at one or more than one temperature sufficient to covalently link the substance to the cellulose fiber; and forming the cellulose fiber with covalently bound substance into the first tobacco smoke filter segment. The substance can be a copper-containing porphyrin or an iron analog of C.I. Reactive Blue 21 dye.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: September 21, 2004
    Assignee: Filligent Limited
    Inventors: Craig A. Lesser, Reid W. Von Borstel
  • Acyl deoxyribonucleoside derivatives and uses thereof
    Patent number: 6743782
    Abstract: The invention relates to compositions comprising acyl derivates of 2′-deoxyribonucleosides. The invention also relates to methods of treating or preventing radiation, mutagen and sunligth-induced cellular damage, methods for improving wound healing and tissue repair, and methods for ameliorating the effects of aging comprising administering the composition of the present invention to an animal.
    Type: Grant
    Filed: January 31, 2000
    Date of Patent: June 1, 2004
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Reid W. Von Borstel, Michael K. Bamat
  • Compounds for the treatment of metabolic disorders
    Publication number: 20040092516
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Application
    Filed: October 14, 2003
    Publication date: May 13, 2004
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Compounds for the treatment of metabolic disorders
    Publication number: 20040077896
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Application
    Filed: October 14, 2003
    Publication date: April 22, 2004
    Inventors: Shalini Sharma, Reid W. von Borstel
  • Antimutagenic compositions for treatment and prevention of photodamage to skin
    Patent number: RE39573
    Abstract: A method of improving DNA repair and reducing DNA damage and for reducing mutation frequency in skin for the purpose of reducing consequences of exposure to solar or ultraviolet radiation is disclosed. The methods comprise administering to the skin a composition containing deoxyribonucleosides in concentrations sufficient to enhance DNA repair or reduce mutation frequency in a vehicle capable of delivering effective amounts of deoxyribonucleosides to the necessary skin cells.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: April 17, 2007
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Reid W. von Borstel, Fedor Romantsev