Patents by Inventor Reinhard Kirsch

Reinhard Kirsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5798365
    Abstract: Compounds of the formula I, ##STR1## and also their tautomeric forms of the formula Ia, ##STR2## in which the substituents R.sup.1 to R.sup.6 and X have said meanings, exhibit antiviral activity.
    Type: Grant
    Filed: August 14, 1995
    Date of Patent: August 25, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Reinhard Kirsch, Jorg-Peter Kleim, Gunther Riess, Manfred Rosner, Irvin Winkler
  • Patent number: 5723461
    Abstract: Disclosed are quinoxalinone compounds of the formula I or Ia ##STR1## and physiologically tolerated salts and prodrugs thereof, in which n=zero, one or two;R.sup.1 =fluorine, chlorine, hydroxyl or C.sub.1 -C.sub.3 -alkoxy; R.sup.2 =C.sub.1 -C.sub.4 -alkyl which is unsubstituted or is substituted by hydroxyl, C.sub.1 -C.sub.4 -alkoxy or C.sub.1 -C.sub.4 -alkylthio; R.sup.3 =C.sub.1 -C.sub.6 -alkyloxycarbonyl or C.sub.2 -C.sub.6 -alkenyloxycarbonyl, and X=oxygen, sulfur or selenium, a process for their preparation and pharmaceutical compositions containing the compounds.
    Type: Grant
    Filed: October 17, 1995
    Date of Patent: March 3, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Manfred Rosner, Uta-Maria Billhardt-Troughton, Reinhard Kirsch, Jorg-Peter Kleim, Christoph Meichsner, Gunther Riess, Irvin Winkler
  • Patent number: 5189165
    Abstract: A process for preparing a compound I ##STR1## with A=t-butyl, aryl andR=alkyl, alkenyl, alkynyl, alkenynyl, cycloalkyl(alkyl), aryl, arylalkyl, alkyl-S-(-O)-arylby reacting a compound III ##STR2## with a compound IV ##STR3## under the conditions of a phase-transfer reaction, is described. The process gives excellent yields and is not associated with the unpleasant odor of mercaptans.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: February 23, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Burdinski, Reinhard Kirsch, Hariolf Kottmann
  • Patent number: 4639463
    Abstract: New phenylsulfonyloxybenzimidazolecarbamates of the formula ##STR1## are described, as are processes for their preparation. The new compounds have anthelmintic activity, including, in particular, against liver flukes.
    Type: Grant
    Filed: December 21, 1983
    Date of Patent: January 27, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Manfred Rosner, Heinz Loewe, Dieter Duwel, Reinhard Kirsch
  • Patent number: 4504490
    Abstract: New benzenesulfonic esters of the formula I ##STR1## and a process for their preparation are described. The new compounds are active against helminths and can thus be used as agents to counter worms in humans and animals.
    Type: Grant
    Filed: September 2, 1983
    Date of Patent: March 12, 1985
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Manfred Rosner, Josef Urbanietz, Heinz Loewe, Dieter Duwel, Reinhard Kirsch
  • Patent number: 4254143
    Abstract: New monocarboxylates of phenylguanidinesulfonic acid esters and a process for their manufacture are described. They are effective as medicaments against helminths and liver flukes when administered orally or parenterally.
    Type: Grant
    Filed: August 16, 1979
    Date of Patent: March 3, 1981
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Dieter Duwel, Reinhard Kirsch
  • Patent number: 4216161
    Abstract: 2-Carbalkoxyamino-benzimidazolyl-5(6)-sulfonic acid phenyl esters are disclosed as well as a process for their manufacture. The new compounds have valuable chemotherapeutic properties and are suitable for combating diseases caused by parasites in humans and animals, such as helminths and liver flukes.
    Type: Grant
    Filed: April 23, 1976
    Date of Patent: August 5, 1980
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Dieter Duwel, Reinhard Kirsch
  • Patent number: 4176192
    Abstract: Substituted phenylguanidines are disclosed as well as a process for their manufacture. The said compounds are active against helminths and liver flukes.
    Type: Grant
    Filed: February 25, 1977
    Date of Patent: November 27, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Dieter Duwel, Reinhard Kirsch
  • Patent number: 4069325
    Abstract: 3-Carbalkoxyamino-1H-2,1,4-benzothiadiazine derivatives are disclosed as well as a process for their manufacture. The compounds are suitable for combatting helminths and especially gastrointestinal Strongylides and liver flukes.
    Type: Grant
    Filed: September 17, 1976
    Date of Patent: January 17, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Dieter Duwel, Reinhard Kirsch
  • Patent number: 4010272
    Abstract: Anthelmintically active basically substituted 2-carbalkoxy-amino-benzimidazolyl-5(6)-phenyl ethers and -ketones are disclosed as well as a process for preparing them. The compounds are chemotherapeutics having a particular activity against ankylostomes, other helminths as well as liver fluke.
    Type: Grant
    Filed: September 8, 1975
    Date of Patent: March 1, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Dieter Duwel, Reinhard Kirsch
  • Patent number: 3997534
    Abstract: The present invention relates to triazinobenzimidazoles and to a process for their preparation.The compounds are chemotherapeutics and are suitable for combating parasitary diseases in humans and animals; they are especially active against nematodes.
    Type: Grant
    Filed: November 7, 1974
    Date of Patent: December 14, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Rochling, Kurt Hartel, Reinhard Kirsch, Dieter Duwel
  • Patent number: 3996368
    Abstract: 2-Carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles are disclosed as well as a process for their manufacture. The new compounds are valuable chemotherapeutic agents and are suitable for combating diseases caused by parasites in humans and animals, such as helminths and liver flukes.
    Type: Grant
    Filed: August 26, 1975
    Date of Patent: December 7, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Dieter Duwel, Reinhard Kirsch
  • Patent number: 3996369
    Abstract: 2-Carbalkoxyamino-benzimidazolyl-5(6)-sulfonic acid phenyl esters are disclosed as well as a process for their manufacture. The new compounds have valuable chemotherapeutic properties and are suitable for combating diseases caused by parasites in humans and animals, such as helminths and liver flukes.
    Type: Grant
    Filed: August 26, 1975
    Date of Patent: December 7, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Dieter Duwel, Reinhard Kirsch
  • Patent number: 3984561
    Abstract: 2-Carbalkoxy-amino-benzimidazole-5(6)-phenyl ethers of the formula (I) ##SPC1##in which R.sub.1 represents alkyl of 1 to 4 carbon atoms, R.sub.2 and R.sub.3 represent, independently of each other, hydrogen, hydroxyl, alkoxy of 1 to 4 carbon atoms, halogen, trifluoromethyl, alkyl of 1 to 4 carbon atoms or carbalkoxy of 1 to 4 carbon atoms in the alkoxy group, R.sub.4 represents hydrogen or chlorine and X represents oxygen or sulfur as anthelmintically active compounds in pharmaceutical preparations and a method for using the same.
    Type: Grant
    Filed: January 23, 1974
    Date of Patent: October 5, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Reinhard Kirsch, Dieter Duwel
  • Patent number: 3980796
    Abstract: Substituted 2-alkoxycarbonylamine-5(6)-phenylmercapto-benzimidazoles are described as well as a process for their manufacture. The compounds are chemotherapeutics being especially suitable for the control of parasites of humans and animals, for example for controlling nematodes.
    Type: Grant
    Filed: May 27, 1975
    Date of Patent: September 14, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gunter Karl Wilhelm Otto Dransch, deceased, by Annelise Klara Helene Wiesenhutter, heiress, Johanna Mathilde Flersheim, heiress, Hilmar Mildenberger, Dieter Duwel, Reinhard Kirsch
  • Patent number: 3954791
    Abstract: 2-Carbalkoxy-amino-benzimidazole-5(6)-phenyl ethers of the formula (I) ##SPC1##in which R.sub.1 represents alkyl of 1 to 4 carbon atoms, R.sub.2 and R.sub.3 represent, independently of each other, hydrogen, hydroxyl, alkoxy of 1 to 4 carbon atoms, halogen, trifluoromethyl, alkyl of 1 to 4 carbon atoms or carbalkoxy of 1 to 4 carbon atoms in the alkoxy group, R.sub.4 represents hydrogen or chlorine and X represents oxygen or sulfur, useful as anthelmintics.
    Type: Grant
    Filed: December 26, 1972
    Date of Patent: May 4, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Loewe, Josef Urbanietz, Reinhard Kirsch, Dieter Duwel
  • Patent number: 3948229
    Abstract: A four-cycle internal combustion engine with external ignition, which is equipped with an intake or suction manifold and with a separate forced air supply to the exhaust channels; to that end an air supply channel is cast-in adjacent one of the exhaust channels provided in a cast cylinder head, whereby the air supply channel is in communication with a slot extending along one suction pipe side in the longitudinal direction of the engine block; the slot is covered off on its open side by a flange of the intake or suction manifold and is operatively connected with the individual exhaust channels by way of cross bores provided in the cylinder head.
    Type: Grant
    Filed: September 4, 1974
    Date of Patent: April 6, 1976
    Assignee: Daimler-Benz Aktiengesellschaft
    Inventors: Jorg Abthoff, Reinhard Kirsch, Rolf Ohlendorf, Franz Ruf