Abstract: A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) in fluid communication with the patient line (50), the filter set (100) including a filter membrane (120, such as a sterilizing grade or a bacteria reduction filter membrane) positioned and arranged such that fresh PD fluid flows through the filter membrane (120) into a filtered fluid compartment (106f), wherein the filtered fluid compartment (106f) includes an outlet (106t) to a port (106p), and wherein the port (106p) is in fluid communication with a used PD fluid tube (106u) positioned and arranged to carry used PD fluid past the filter membrane (120) without contacting the filter membrane (120). A method for priming filter set (100) is also disclosed.

Abstract: A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) including a filter housing (102) having a tubular filter membrane (120, such as a sterilizing grade or bacteria reduction filter membrane) positioned and arranged to filter fresh PD fluid flowing radially across the tubular filter membrane (120), and a transfer set-side port (106p) positioned and arranged to receive (i) filtered fresh PD fluid during a patient fill and (ii) used PD fluid during a patient drain.

Abstract: A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) including a filter housing (102) having an upper housing plate (102u) and a lower housing plate (102l), and a filter membrane (112, such as a sterilizing grade or a bacteria reduction filter membrane) located between the upper housing plate (102u) and the lower housing plate (102l), the filter set (100) further including a lumen-side connector (104) configured to connect to the patient line (50), the lumen-side connector (104) connected to the filter housing (102) via at least one of a fresh PD fluid tube (106a) or a used PD fluid tube (106b). A method for manufacturing the filter set (100) is also disclosed.

Abstract: A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) (which may be a dual lumen patient line) extending from the PD machine (20); a filter set (100) in fluid communication with the patient line (50), the filter set (100) including a plurality of hollow fiber membranes (120, e.g., sterilizing grade or bacteria reduction hollow fiber membranes) positioned and arranged such that fresh PD fluid flows through porous walls of the hollow fiber membranes (120) prior to exiting the filter set (100).

Abstract: A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); a filter set (100) in fluid communication with the patient line (50), the filter set (100) including an air diverting net (112) configured to divert air from PD fluid flowing through the filter set (100); and an air return line (58) positioned to return PD fluid containing air back to the PD machine (20).

Abstract: A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) in fluid communication with the patient line (50), the filter set (100) including at least one filter membrane (120a, 120b, such as a bacteria reduction or sterilizing grade filter membrane) positioned and arranged such that fresh PD fluid flows through the at least one filter membrane (120a, 120b) prior to exiting the filter set (100), the filter set (100) further including a used PD fluid tube (106u) positioned and arranged to carry used PD fluid past the at least one filter membrane (120a, 120b) without contacting the at least one filter membrane (120a, 120b). A method for priming filter set (100) is also disclosed.

Abstract: The present disclosure relates to a spinneret for producing hollow fiber membranes in a phase inversion process.

Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.

Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.

Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.

Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.

Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.

Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.

Abstract: A device for testing at least one plug-in element includes a plug-in element receptacle and a test element receptacle, which are adapted to be movable along a test axis for establishing a plug-in connection. A force sensor is configured and disposed to detect a force along the test axis when the plug-in connection is established. A compensating element is configured and disposed for compensating for an offset between the plug-in element and a test element. The compensating element is configured to be at least partially elastic so that the test element is elastically movable to compensate for alignment deviations from the test axis. A method for testing at least one plug-in element is provided along with a method for producing the compensating element.

Abstract: The present disclosure relates to a spinneret for producing hollow fiber membranes in a phase inversion process.

Abstract: The present disclosure relates to capillary dialyzers for blood purification, in particular, capillary dialyzers suitable for home hemodialysis systems.

Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.

Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.

Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.