Patents by Inventor René Martin

René Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200165204
    Abstract: A method for producing a radiofluorinated compound having an aromatic or heteroaromatic ring carrying [18F] fluorine as first substituent, a bonding unit, which can bind to a peptide or peptide mimetic, and a spacer group connected via bond A1 to the bonding unit and via bond A2 to the ring, wherein the bonding unit has second substituent(s) —OH, —CONH, and/or —COOH. The steps include (a) providing a precursor having the ring carrying a substituent Y, bonding unit with the second substituent(s), and spacer group, wherein substituent Y is —N+(R1R2R3), —NO2, —Cl, —Br, —F, or —I, and R1, R2, and R3 are independently C1-C6 alkyl; and (b) reacting the precursor with a [18F] fluoride anion in the presence of an activation salt to the radiofluorinated compound, which has a cation N+(R4R5R6R7) with R4, R5, R6, and R7 being independently C1-C6 alkyl, wherein the substituent Y is replaced by [18F] fluoride.
    Type: Application
    Filed: January 31, 2020
    Publication date: May 28, 2020
    Applicant: ABX advanced biochemical compounds GmbH
    Inventors: René MARTIN, René SMITS, Ronny HESSE, Alexander HOEPPING, Marco MÜLLER, Sandra HÜBNER
  • Publication number: 20200157396
    Abstract: Various shaped abrasive particles are disclosed. Each shaped abrasive particle includes a body having at least one major surface and a side surface extending from the major surface.
    Type: Application
    Filed: January 22, 2020
    Publication date: May 21, 2020
    Inventors: Todd M. COTTER, Francois WAGNER, Rene G. DEMERS, Richard J. KLOK, Alexandra MARAZANO, Adam D. LIOR, James A. SALVATORE, Sujatha K. IYENGAR, David F. LOUAPRE, Sidath S. WIJESOORIYA, Ronald Christopher MOTTA, Gary A. GUERTIN, Michael D. KAVANAUGH, Doruk O. YENER, Jennifer H. CZEREPINSKI, Jun JIA, Frederic JOSSEAUX, Ralph BAUER, Frank J. CSILLAG, Yang ZHONG, James P. Stewart, Mark P. DOMBROWSKI, Sandhya JAYARAMAN RUKMANI, Amandine MARTIN, Stephen E. FOX, Nilanjan SARANGI, Dean S. MATSUMOTO
  • Publication number: 20200123262
    Abstract: Provided herein is are methods of treating Chronic Obstructive Pulmonary Disease (COPD) in a patient, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.
    Type: Application
    Filed: May 24, 2019
    Publication date: April 23, 2020
    Inventors: Rene van der Merwe, Christine Ward, Ubaldo Martin, Lorin Roskos, Bing Wang
  • Patent number: 10563105
    Abstract: Various shaped abrasive particles are disclosed. Each shaped abrasive particle includes a body having at least one major surface and a side surface extending from the major surface.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: February 18, 2020
    Assignee: SAINT-GOBAIN CERAMICS & PLASTICS, INC.
    Inventors: Todd M. Cotter, Sidath S. Wijesooriya, Ronald Christopher Motta, Gary A. Guertin, Michael D. Kavanaugh, Doruk O. Yener, Jennifer H. Czerepinski, Jun Jia, Frederic Josseaux, Ralph Bauer, Frank J. Csillag, Francois Wagner, Yang Zhong, James P. Stewart, Mark P. Dombrowski, Sandhya Jayaraman Rukmani, Amandine Martin, Stephen E. Fox, Nilanjan Sarangi, Dean S. Matsumoto, Rene G. Demers, Richard J. Klok, Alexandra Marazano, Adam D. Lior, James A. Salvatore, Sujatha Iyengar, David F. Louapre
  • Patent number: 10487377
    Abstract: One aspect generally relates to a Cr, Ni, Mo and Co alloy, with tightly controlled levels of impurities. One aspect relates to an alloy including about 10 to about 30 weight % Cr, about 20 to about 50 weight % Ni, about 2 to about 20 weight % Mo, about 10 to about 50 weight % Co, and less than about 0.01 weight % Al, wherein each weight % is based on the total weight of the alloy.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: November 26, 2019
    Assignees: Heraeus Deutschland GmbH & Co. KG, Saes Smart Materials, Inc.
    Inventors: René Richter, Jörg-Martin Gebert, Heiko Specht, Francis E. Sczerzenie, Radhakrishnan M. Manjeri, Weimin Yin
  • Publication number: 20190263756
    Abstract: A method for producing a radiofluorinated compound having an aromatic or heteroaromatic ring carrying [18F] fluorine as first substituent, a bonding unit, which can bind to a peptide or peptide mimetic, and a spacer group connected via bond A1 to the bonding unit and via bond A2 to the ring, wherein the bonding unit has second substituent(s) —OH, —CONH, and/or —COOH. The steps include (a) providing a precursor having the ring carrying a substituent Y, bonding unit with the second substituent(s), and spacer group, wherein substituent Y is —N+(R1R2R3), —NO2, —Cl, —Br, —F, or —I, and R1, R2, and R3 are independently C1-C6 alkyl; and (b) reacting the precursor with a [18F] fluoride anion in the presence of an activation salt to the radiofluorinated compound, which has a cation N+(R4R5R6R7) with R4, R5, R6, and R7 being independently C1-C6 alkyl, wherein the substituent Y is replaced by [18F] fluoride.
    Type: Application
    Filed: November 17, 2017
    Publication date: August 29, 2019
    Applicant: ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH
    Inventors: René MARTIN, René SMITS, Ronny HESSE, Alexander HOEPPING, Marco MÜLLER, Sandra HÜBNER
  • Publication number: 20190251096
    Abstract: An enterprise system which facilitates synchronization of offline data. Offline data created during an offline session or sessions (collectively an offline session) prior to synchronization is assigned a temporary key. Changes of offline data created during an offline session is assigned the temporary key of the data to which the change is associated. The temporary key is mapped to a new created backend key and stored in a mapping table. Using the mapping table, temporary keys associated with the changes are swapped with backend keys which the temporary keys are mapped. This maintains data persistency of newly created and change data during an offline session.
    Type: Application
    Filed: April 23, 2019
    Publication date: August 15, 2019
    Inventors: Gerd Martin Ritter, Pradeep Kumar Singh, Tim Kornmann, Rene Gross
  • Patent number: 10376348
    Abstract: An automatic toothbrush (100), including: a body (102) having opposed ends, a cavity (105) situated between the opposed ends, and an opening (107) situated at one of the opposed ends; an output shaft (120) having first and second ends (124, 122) and extending through the opening such that the second end (122) is outside of the cavity, the output shaft having a plurality of bends (139, 141, 143,145) situated between the second end and the opening; and an oral cleaning tool (104) configured to be press fit onto that portion of the shaft which has the plurality of bends.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: August 13, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Siegfried Sablatschan, Rene Michael Brunner, Christian Martin Rassi
  • Patent number: 10311082
    Abstract: An enterprise system which facilitates synchronization of offline data. Offline data created during an offline session or sessions (collectively an offline session) prior to synchronization is assigned a temporary key. Changes of offline data created during an offline session is assigned the temporary key of the data to which the change is associated. The temporary key is mapped to a new created backend key and stored in a mapping table. Using the mapping table, temporary keys associated with the changes are swapped with backend keys which the temporary keys are mapped. This maintains data persistency of newly created and change data during an offline session.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: June 4, 2019
    Assignee: SAP SE
    Inventors: Gerd Martin Ritter, Pradeep Kumar Singh, Tim Kornmann, Rene Gross
  • Publication number: 20190006081
    Abstract: An apparatus for electrically connecting at least four electrical conductors includes a connecting element and at least four shielding pipes, which are each provided for receiving at least one conductor. In order to enable a simple and economical connection, the connecting element forms pipe connection pieces and each connection piece is integrally joined or materially bonded to a respective shielding pipe.
    Type: Application
    Filed: November 11, 2016
    Publication date: January 3, 2019
    Inventors: JENS HOPPE, KARSTEN LOPPACH, KLAUS MUELLER, JOHANN SCHLAGER, THOMAS WENDE, RENE MARTIN WIMMER
  • Patent number: 10053428
    Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: August 21, 2018
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Michael Hahn, Markus Follmann, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, Ildiko Terebesi, Dieter Lang, René Martin, Walter Hübsch
  • Patent number: 9951332
    Abstract: The present invention concerns the use of particular RNA sequences as a medicament. More precisely, it concerns the use of small nucleolar RNAs (snoRNAs) which the inventor has shown to be involved in the mechanisms of aging. The snoRNAs of the invention can be used in particular to increase the stress resistance of a subject and to fight against the harmful effects of aging, typically for preventing or treating a degenerative disease, a laminopathy, diabetes, obesity or a cancer and, more generally, to prolong the lifespan of a subject. The snoRNAs of the invention can also be used in the treatment of infertility. The invention further relates to vectors, cells, transgenic animals and compositions capable of expressing an snoRNA of the invention, and methods using any of the above products of the invention as a tool for identification of a molecule active in the prevention or treatment of a pathology, abnormality or disorder linked to a mechanism of aging.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: April 24, 2018
    Assignee: NINOVAX
    Inventor: Jean-René Martin
  • Patent number: 9859701
    Abstract: A connection element for electrically conductive connections of at least four electric conductors. The connection element has a metallic electrode which has a cavity for merging the conductors and an opening into the cavity for each conductor. At least the outer surface of the electrode is surrounded with a paper insulation.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: January 2, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Jens Hoppe, Karsten Loppach, Thomas Wende, Rene Martin Wimmer
  • Publication number: 20170316845
    Abstract: An irradiation facility for a nuclear reactor, a method of removing thermal heat from an irradiated object and adjusting an energy distribution/neutron/gamma-ray flux ratio of irradiation, and a product obtainable by the method.
    Type: Application
    Filed: May 25, 2017
    Publication date: November 2, 2017
    Inventors: Peter Bode, Antonia Georgieva Denkova, Hurbert Theodoor Wolterbeek, Rene Martin Gommers, Baukje Elisabeth Terpstra
  • Publication number: 20170260139
    Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.
    Type: Application
    Filed: May 19, 2017
    Publication date: September 14, 2017
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: MICHAEL HAHN, MARKUS FOLLMANN, EVA-MARIA BECKER, JOHANNES-PETER STASCH, JOERG KELDENICH, MARTINA DELBECK, HANNA TINEL, FRANK WUNDER, JOACHIM MITTENDORF, ILDIKO TEREBESI, DIETER LANG, RENÉ MARTIN, WALTER HÜBSCH
  • Patent number: 9688636
    Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: June 27, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Michael Hahn, Markus Follmann, Walter Hübsch, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, Ildiko Terebesi, Dieter Lang, René Martin
  • Publication number: 20160298112
    Abstract: The present invention concerns the use of particular RNA sequences as a medicament. More precisely, it concerns the use of small nucleolar RNAs (snoRNAs) which the inventors have shown to be involved in the mechanisms of aging. The snoRNAs of the invention can be used in particular to increase the stress resistance of a subject, to fight against the harmful effects of aging, typically for preventing or treating a degenerative disease, a laminopathy, diabetes, obesity or a cancer and, more generally, to prolong the lifespan of a subject. The snoRNAs of the invention can also be used in the treatment of infertility. The invention further relates to vectors, cells, transgenic animals and compositions capable of expressing a snoRNA of the invention, and methods using any of the above products of the invention as a tool for identification of a molecule active in the prevention or treatment of a pathology, abnormality or disorder linked to a mechanism of aging.
    Type: Application
    Filed: November 7, 2014
    Publication date: October 13, 2016
    Inventor: JEAN-RENÉ MARTIN
  • Publication number: 20160254657
    Abstract: A connection element for electrically conductive connections of at least four electric conductors. The connection element has a metallic electrode which has a cavity for merging the conductors and an opening into the cavity for each conductor. At least the outer surface of the electrode is surrounded with a paper insulation.
    Type: Application
    Filed: August 28, 2014
    Publication date: September 1, 2016
    Inventors: JENS HOPPE, KARSTEN LOPPACH, THOMAS WENDE, RENE MARTIN WIMMER
  • Publication number: 20150148376
    Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.
    Type: Application
    Filed: January 29, 2015
    Publication date: May 28, 2015
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Michael HAHN, Markus Follmann, Walter Hübsch, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, IIdiko Terebesi, Dieter Lang, René Martin
  • Patent number: D739978
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: September 29, 2015
    Inventor: Rene-Martin Oliveras