Patents by Inventor René Martin
René Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240116109Abstract: The present invention relates to a process for producing a three-dimensional (3D) object by employing a three-dimensional (3D) printing process wherein a granulate having an particle size in the range of 0.2 to 1 mm is used as a starting material to be printed within said 3D printing process, employing a 3D extrusion printer. In one preferred embodiment, the process according to the present invention is employed for producing a 3D greenbody. The invention further relates to 3D objects as such and the corresponding processes for obtaining such 3D objects, in particular a 3D green body, a 3D brown body and a 3D sintered body.Type: ApplicationFiled: October 13, 2020Publication date: April 11, 2024Inventors: Rene ARBTER, Thorsten Martin STAUDT, Rudolf SEILER, OLeg STEINKE, Sascha Tim SCHWENDY
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Patent number: 11932802Abstract: Various shaped abrasive particles are disclosed. Each shaped abrasive particle includes a body having at least one major surface and a side surface extending from the major surface.Type: GrantFiled: December 2, 2022Date of Patent: March 19, 2024Assignee: SAINT-GOBAIN CERAMICS & PLASTICS, INC.Inventors: Todd M. Cotter, Francois Wagner, Rene G. Demers, Richard J. Klok, Alexandra Marazano, Adam D. Lior, James A. Salvatore, Sujatha K. Iyengar, David F Louapre, Sidath S. Wijesooriya, Ronald Christopher Motta, Gary A. Guertin, Michael D. Kavanaugh, Doruk O. Yener, Jennifer H. Czerepinski, Jun Jia, Frederic Josseaux, Ralph Bauer, Frank J. Csillag, Yang Zhong, James P. Stewart, Mark P. Dombrowski, Sandhya Jayaraman Rukmani, Amandine Martin, Stephen E. Fox, Nilanjan Sarangi, Dean S. Matsumoto
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Publication number: 20230183705Abstract: The present invention relates to the field of medicine. It relates more particularly to a product suppressing or reducing the expression or activity of the human small nucleolar RNA (snoRNA) of sequence SEQ ID NO: 1 for use as a medicament. The product of the invention is preferably for use for preventing or treating cancer. The description further relates to vectors, cells, vehicles and compositions capable of delivering and expressing a product suppressing or reducing the expression or activity of the human small nucleolar RNA (snoRNA) of sequence SEQ ID NO: 1, and to uses thereof.Type: ApplicationFiled: March 4, 2021Publication date: June 15, 2023Inventors: JEAN-RENÉ MARTIN, JÉRÔME BIGNON
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Patent number: 11053200Abstract: A method for producing a radiofluorinated compound having an aromatic or heteroaromatic ring carrying [18F] fluorine as first substituent, a bonding unit, which can bind to a peptide or peptide mimetic, and a spacer group connected via bond A1 to the bonding unit and via bond A2 to the ring, wherein the bonding unit has second substituent(s) —OH, —CONH, and/or —COOH. The steps include (a) providing a precursor having the ring carrying a substituent Y, bonding unit with the second substituent(s), and spacer group, wherein substituent Y is —N+(R1R2R3), —NO2, —Cl, —Br, —F, or —I, and R1, R2, and R3 are independently C1-C6 alkyl; and (b) reacting the precursor with a [18F] fluoride anion in the presence of an activation salt to the radiofluorinated compound, which has a cation N+(R4R5R6R7) with R4, R5, R6, and R7 being independently C1-C6 alkyl, wherein the substituent Y is replaced by [18F] fluoride.Type: GrantFiled: January 31, 2020Date of Patent: July 6, 2021Assignee: ABX advanced biochemical compounds GmbHInventors: René Martin, René Smits, Ronny Hesse, Alexander Hoepping, Marco Müller, Sandra Hübner
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Patent number: 10994936Abstract: A conveyor comprises an endless belt and a belt return device. The endless belt comprises an upper run and a lower run and is configured to convey conveying material in a conveying direction. An intermediate space is defined between the upper run and the lower run. The belt return device facilitates transitioning of the endless belt between the lower run and the upper run. The endless belt defines at least one passage opening which allows the exit of at least a portion of an intermediate space material which is formed by a portion of the conveying material which has reached the intermediate space. At least a portion of the endless belt comprises a conveyor track and a passage track. The passage track defines the at least one passage opening. The conveyor track and the passage track are arranged side by side in the conveying direction.Type: GrantFiled: December 18, 2019Date of Patent: May 4, 2021Assignees: Mayfran Limburg B.V., Mayfran International Inc., Tsubakimoto Mayfran Inc.Inventors: Mark Andrew Mandzukic, Ryuichi Hori, Nebojsa Petrovic, Rene Martin Sieben, John Joseph Zolcak
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Patent number: 10978236Abstract: An apparatus for electrically connecting at least four electrical conductors includes a connecting element and at least four shielding pipes, which are each provided for receiving at least one conductor. In order to enable a simple and economical connection, the connecting element forms pipe connection pieces and each connection piece is integrally joined or materially bonded to a respective shielding pipe.Type: GrantFiled: November 11, 2016Date of Patent: April 13, 2021Assignee: Siemens AktiengesellschaftInventors: Jens Hoppe, Karsten Loppach, Klaus Mueller, Johann Schlager, Thomas Wende, Rene Martin Wimmer
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Patent number: 10759760Abstract: A method for producing a radiofluorinated compound having an aromatic or heteroaromatic ring carrying [18F] fluorine as first substituent, a bonding unit, which can bind to a peptide or peptide mimetic, and a spacer group connected via bond A1 to the bonding unit and via bond A2 to the ring, wherein the bonding unit has second substituent(s) —OH, —CONH, and/or —COOH. The steps include (a) providing a precursor having the ring carrying a substituent Y, bonding unit with the second substituent(s), and spacer group, wherein substituent Y is —N+(R1R2R3), —NO2, —Cl, —Br, —F, or —I, and R1, R2, and R3 are independently C1-C6 alkyl; and (b) reacting the precursor with a [18F] fluoride anion in the presence of an activation salt to the radiofluorinated compound, which has a cation N+(R4R5R6R7) with R4, R5, R6, and R7 being independently C1-C6 alkyl, wherein the substituent Y is replaced by [18F] fluoride.Type: GrantFiled: November 17, 2017Date of Patent: September 1, 2020Assignee: ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBHInventors: René Martin, René Smits, Ronny Hesse, Alexander Hoepping, Marco Müller, Sandra Hübner
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Publication number: 20200165204Abstract: A method for producing a radiofluorinated compound having an aromatic or heteroaromatic ring carrying [18F] fluorine as first substituent, a bonding unit, which can bind to a peptide or peptide mimetic, and a spacer group connected via bond A1 to the bonding unit and via bond A2 to the ring, wherein the bonding unit has second substituent(s) —OH, —CONH, and/or —COOH. The steps include (a) providing a precursor having the ring carrying a substituent Y, bonding unit with the second substituent(s), and spacer group, wherein substituent Y is —N+(R1R2R3), —NO2, —Cl, —Br, —F, or —I, and R1, R2, and R3 are independently C1-C6 alkyl; and (b) reacting the precursor with a [18F] fluoride anion in the presence of an activation salt to the radiofluorinated compound, which has a cation N+(R4R5R6R7) with R4, R5, R6, and R7 being independently C1-C6 alkyl, wherein the substituent Y is replaced by [18F] fluoride.Type: ApplicationFiled: January 31, 2020Publication date: May 28, 2020Applicant: ABX advanced biochemical compounds GmbHInventors: René MARTIN, René SMITS, Ronny HESSE, Alexander HOEPPING, Marco MÜLLER, Sandra HÜBNER
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Publication number: 20190263756Abstract: A method for producing a radiofluorinated compound having an aromatic or heteroaromatic ring carrying [18F] fluorine as first substituent, a bonding unit, which can bind to a peptide or peptide mimetic, and a spacer group connected via bond A1 to the bonding unit and via bond A2 to the ring, wherein the bonding unit has second substituent(s) —OH, —CONH, and/or —COOH. The steps include (a) providing a precursor having the ring carrying a substituent Y, bonding unit with the second substituent(s), and spacer group, wherein substituent Y is —N+(R1R2R3), —NO2, —Cl, —Br, —F, or —I, and R1, R2, and R3 are independently C1-C6 alkyl; and (b) reacting the precursor with a [18F] fluoride anion in the presence of an activation salt to the radiofluorinated compound, which has a cation N+(R4R5R6R7) with R4, R5, R6, and R7 being independently C1-C6 alkyl, wherein the substituent Y is replaced by [18F] fluoride.Type: ApplicationFiled: November 17, 2017Publication date: August 29, 2019Applicant: ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBHInventors: René MARTIN, René SMITS, Ronny HESSE, Alexander HOEPPING, Marco MÜLLER, Sandra HÜBNER
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Publication number: 20190006081Abstract: An apparatus for electrically connecting at least four electrical conductors includes a connecting element and at least four shielding pipes, which are each provided for receiving at least one conductor. In order to enable a simple and economical connection, the connecting element forms pipe connection pieces and each connection piece is integrally joined or materially bonded to a respective shielding pipe.Type: ApplicationFiled: November 11, 2016Publication date: January 3, 2019Inventors: JENS HOPPE, KARSTEN LOPPACH, KLAUS MUELLER, JOHANN SCHLAGER, THOMAS WENDE, RENE MARTIN WIMMER
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Patent number: 10053428Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.Type: GrantFiled: May 19, 2017Date of Patent: August 21, 2018Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Michael Hahn, Markus Follmann, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, Ildiko Terebesi, Dieter Lang, René Martin, Walter Hübsch
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Patent number: 9951332Abstract: The present invention concerns the use of particular RNA sequences as a medicament. More precisely, it concerns the use of small nucleolar RNAs (snoRNAs) which the inventor has shown to be involved in the mechanisms of aging. The snoRNAs of the invention can be used in particular to increase the stress resistance of a subject and to fight against the harmful effects of aging, typically for preventing or treating a degenerative disease, a laminopathy, diabetes, obesity or a cancer and, more generally, to prolong the lifespan of a subject. The snoRNAs of the invention can also be used in the treatment of infertility. The invention further relates to vectors, cells, transgenic animals and compositions capable of expressing an snoRNA of the invention, and methods using any of the above products of the invention as a tool for identification of a molecule active in the prevention or treatment of a pathology, abnormality or disorder linked to a mechanism of aging.Type: GrantFiled: November 7, 2014Date of Patent: April 24, 2018Assignee: NINOVAXInventor: Jean-René Martin
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Patent number: 9859701Abstract: A connection element for electrically conductive connections of at least four electric conductors. The connection element has a metallic electrode which has a cavity for merging the conductors and an opening into the cavity for each conductor. At least the outer surface of the electrode is surrounded with a paper insulation.Type: GrantFiled: August 28, 2014Date of Patent: January 2, 2018Assignee: Siemens AktiengesellschaftInventors: Jens Hoppe, Karsten Loppach, Thomas Wende, Rene Martin Wimmer
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Publication number: 20170316845Abstract: An irradiation facility for a nuclear reactor, a method of removing thermal heat from an irradiated object and adjusting an energy distribution/neutron/gamma-ray flux ratio of irradiation, and a product obtainable by the method.Type: ApplicationFiled: May 25, 2017Publication date: November 2, 2017Inventors: Peter Bode, Antonia Georgieva Denkova, Hurbert Theodoor Wolterbeek, Rene Martin Gommers, Baukje Elisabeth Terpstra
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Publication number: 20170260139Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.Type: ApplicationFiled: May 19, 2017Publication date: September 14, 2017Applicant: BAYER PHARMA AKTIENGESELLSCHAFTInventors: MICHAEL HAHN, MARKUS FOLLMANN, EVA-MARIA BECKER, JOHANNES-PETER STASCH, JOERG KELDENICH, MARTINA DELBECK, HANNA TINEL, FRANK WUNDER, JOACHIM MITTENDORF, ILDIKO TEREBESI, DIETER LANG, RENÉ MARTIN, WALTER HÜBSCH
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Patent number: 9688636Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.Type: GrantFiled: January 29, 2015Date of Patent: June 27, 2017Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Michael Hahn, Markus Follmann, Walter Hübsch, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, Ildiko Terebesi, Dieter Lang, René Martin
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Publication number: 20160298112Abstract: The present invention concerns the use of particular RNA sequences as a medicament. More precisely, it concerns the use of small nucleolar RNAs (snoRNAs) which the inventors have shown to be involved in the mechanisms of aging. The snoRNAs of the invention can be used in particular to increase the stress resistance of a subject, to fight against the harmful effects of aging, typically for preventing or treating a degenerative disease, a laminopathy, diabetes, obesity or a cancer and, more generally, to prolong the lifespan of a subject. The snoRNAs of the invention can also be used in the treatment of infertility. The invention further relates to vectors, cells, transgenic animals and compositions capable of expressing a snoRNA of the invention, and methods using any of the above products of the invention as a tool for identification of a molecule active in the prevention or treatment of a pathology, abnormality or disorder linked to a mechanism of aging.Type: ApplicationFiled: November 7, 2014Publication date: October 13, 2016Inventor: JEAN-RENÉ MARTIN
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Publication number: 20160254657Abstract: A connection element for electrically conductive connections of at least four electric conductors. The connection element has a metallic electrode which has a cavity for merging the conductors and an opening into the cavity for each conductor. At least the outer surface of the electrode is surrounded with a paper insulation.Type: ApplicationFiled: August 28, 2014Publication date: September 1, 2016Inventors: JENS HOPPE, KARSTEN LOPPACH, THOMAS WENDE, RENE MARTIN WIMMER
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Publication number: 20150148376Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.Type: ApplicationFiled: January 29, 2015Publication date: May 28, 2015Applicant: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Michael HAHN, Markus Follmann, Walter Hübsch, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, IIdiko Terebesi, Dieter Lang, René Martin
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Patent number: D739978Type: GrantFiled: July 22, 2013Date of Patent: September 29, 2015Inventor: Rene-Martin Oliveras