Patents by Inventor Reuven Y. FILMAN
Reuven Y. FILMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11931552Abstract: A drug delivery device includes a compartment sized to receive a cartridge. The compartment includes a cartridge bay that opens so that a cartridge may be inserted into the cartridge bay and that closes when the cartridge is received by the compartment. The drug delivery device also includes a housing including an expanding assembly. The expanding assembly includes a driver supported from a distal end by a linear stabilizer that includes a bearing configured to push against the housing. The driver is rotated by a motor. The expanding assembly also includes two mid screws threadedly connected to the driver, a plunger driver threadedly connected to the two mid screws, and an anti-rotational guide that prevents rotation of the plunger driver.Type: GrantFiled: November 20, 2021Date of Patent: March 19, 2024Assignee: West Pharma Services IL, Ltd.Inventors: Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Patent number: 11819673Abstract: In some embodiments a system and method are described for safeguarding a hazard. The hazard, for example a needle point, may be moved between a protected retracted position, an active extended position and/or an intermediate position. Optionally in the retracted position, the hazard may be protected inside a housing. Optionally in the extended position, the hazard may be exposed. Optionally, in the intermediate position the hazard may be partially protected and/or concealed, for example by a shield and/or in an indentation. In some embodiments, compromising a shield causes the hazard to be retracted to the retracted position.Type: GrantFiled: August 3, 2021Date of Patent: November 21, 2023Assignee: West Pharma. Services, IL, Ltd.Inventors: Michael Yudelevich, Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Patent number: 11819666Abstract: A modular drive train is selectively securable within a wearable injector. The drive train includes a chassis and a telescoping driving assembly mounted within the chassis. The driving assembly includes a first shaft rotatable relative to the chassis, and a second shaft connected with the first shaft and axially movable relative thereto. Rotation of the first shaft axially drives the second shaft. The chassis includes one of a bearing and an elastically expandable collar projecting axially forward into the chassis from a rear end thereof, and the first shaft includes the other of the bearing and the elastically expandable collar projecting axially rearwardly from a rear end thereof. The collar is configured to elastically snap over an interference element of the bearing, whereby engagement of the collar with the bearing axially secures the first shaft to the chassis and permits rotation of the first shaft about the bearing.Type: GrantFiled: May 25, 2018Date of Patent: November 21, 2023Assignee: West Pharma. Services IL, Ltd.Inventors: Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Patent number: 11642470Abstract: An injector includes an injector housing, an activation button assembly movably mounted to the injector housing and operatively connected to the injection needle, and a cartridge door movably mounted to the injector housing between an open position and a closed position. A deflectable interference member engaging the rear end flange of the cartridge has a resting position configured to limit an insertion depth of a cartridge into an interior channel of the cartridge door to a sealed position, wherein the cartridge piercing needle does not fully penetrate a pierceable septum of the cartridge. The cartridge door includes an interior channel having a cartridge mounted therein. The cartridge includes a substance to be dispensed. The substance includes an anti-C5 antibody or antigen binding fragment thereof, and optionally further includes a recombinant human hyaluronidase enzyme. A method of treating a complement associated condition using an injector thereof.Type: GrantFiled: January 31, 2020Date of Patent: May 9, 2023Assignee: West Pharma. Services IL, Ltd.Inventors: Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Patent number: 11571517Abstract: An injector includes an injector housing, an activation button assembly translatable from an unactuated position to an actuated position and a cartridge door movably mounted to the injector housing between an open position and a closed position. A deflectable interference member has a resting position configured to limit an insertion depth of a cartridge into an interior channel of the cartridge door to a sealed position, wherein the cartridge piercing needle does not fully penetrate a pierceable septum of the cartridge. Movement of the activation button assembly from the unactuated position to the actuated position thereof, in the closed position of the cartridge door, deflects the interference element out of the resting position thereof, thereby enabling further advancement of the cartridge into the interior channel of the cartridge door to an unsealed position, wherein the cartridge piercing needle fully penetrates the pierceable septum.Type: GrantFiled: August 2, 2018Date of Patent: February 7, 2023Assignee: West Pharma. Services IL, Ltd.Inventors: Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Publication number: 20220080125Abstract: A drug delivery device includes a compartment sized to receive a cartridge. The compartment includes a cartridge bay that opens so that a cartridge may be inserted into the cartridge bay and that closes when the cartridge is received by the compartment. The drug delivery device also includes a housing including an expanding assembly. The expanding assembly includes a driver supported from a distal end by a linear stabilizer that includes a bearing configured to push against the housing. The driver is rotated by a motor. The expanding assembly also includes two mid screws threadedly connected to the driver, a plunger driver threadedly connected to the two mid screws, and an anti-rotational guide that prevents rotation of the plunger driver.Type: ApplicationFiled: November 20, 2021Publication date: March 17, 2022Inventors: Yossi BAR-EL, Gil YIGAL, Reuven Y. FILMAN
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Patent number: 11253429Abstract: An alignment assembly for a cartridge interface of a drug delivery device is disclosed. The assembly optionally includes a coupling for opening fluid communication between the cartridge and the delivery device. For example, the coupling optionally includes a cannula insertable through a septum of the cartridge. The assembly may include a guide for positioning the cartridge and/or an access channel thereof within a first precision of a loaded position. The assembly optionally includes a cartridge engagement fitting (for example a gripping expander sleeve collar) attached to the coupling. Optionally when the cartridge is engaged to the fitting, the coupling is retained in connection with the access channel to within a second precision. The second precision is optionally higher than the first precision. In some embodiments one or more compliant supports movably retain the fitting oriented to engage the cartridge when the access channel is in the loaded position.Type: GrantFiled: March 8, 2019Date of Patent: February 22, 2022Assignee: West Pharma. Services IL, Ltd.Inventors: Yossi Bar-El, Tomer Solomon, Reuven Y. Filman
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Patent number: 11207465Abstract: A method and assembly are disclosed for interfacing between a drug cartridge and a drug delivery device. Optionally, the drug delivery device includes a compartment that retains the cartridge during drug delivery and/or a stopper pushing assembly mounted to the device behind (proximal to) the compartment. In some embodiments, the cartridge may be inserted laterally into the compartment in front of the pushing assembly. For example, the delivery device may include a moving cartridge bay. The cartridge is optionally inserted into the bay and/or the bay and cartridge optionally move into the cartridge compartment. Alternatively or additionally, the cartridge compartment may have a proximal opening into which the cartridge is inserted and/or the pushing assembly may be moved into position after insertion of the cartridge. In some embodiments the cartridge may have a distal seal that is broken by a longitudinal movement.Type: GrantFiled: June 3, 2016Date of Patent: December 28, 2021Assignee: West Pharma. Services IL. Ltd.Inventors: Yossi Bar-El, gil Yigal, Reuven Y. Filman
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Publication number: 20210361883Abstract: In some embodiments a system and method are described for safeguarding a hazard. The hazard, for example a needle point, may be moved between a protected retracted position, an active extended position and/or an intermediate position. Optionally in the retracted position, the hazard may be protected inside a housing. Optionally in the extended position, the hazard may be exposed. Optionally, in the intermediate position the hazard may be partially protected and/or concealed, for example by a shield and/or in an indentation. In some embodiments, compromising a shield causes the hazard to be retracted to the retracted position.Type: ApplicationFiled: August 3, 2021Publication date: November 25, 2021Inventors: Michael YUDELEVICH, Yossi BAR-EL, Gil YIGAL, Reuven Y. FILMAN
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Patent number: 11103652Abstract: In some embodiments a system and method are described for safeguarding a hazard, the hazard, for example a needle point, may be moved between a protected retracted position, an active extended position and/or an intermediate position. Optionally in the retracted position, the hazard may be protected inside a housing. Optionally in the extended position, the hazard may be exposed. Optionally, in the intermediate position the hazard may be partially protected and/or concealed, for example by a shield and/or in an indentation. In some embodiments, compromising a shield causes the hazard to be retracted to the retracted position.Type: GrantFiled: June 1, 2017Date of Patent: August 31, 2021Assignee: WEST PHARMA. SERVICES IL, LTD.Inventors: Michael Yudelevich, Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Publication number: 20210138157Abstract: A modular drive train is selectively securable within a wearable injector. The drive train includes a chassis and a telescoping driving assembly mounted within the chassis. The driving assembly includes a first shaft rotatable relative to the chassis, and a second shaft connected with the first shaft and axially movable relative thereto. Rotation of the first shaft axially drives the second shaft. The chassis includes one of a bearing and an elastically expandable collar projecting axially forward into the chassis from a rear end thereof, and the first shaft includes the other of the bearing and the elastically expandable collar projecting axially rearwardly from a rear end thereof. The collar is configured to elastically snap over an interference element of the bearing, whereby engagement of the collar with the bearing axially secures the first shaft to the chassis and permits rotation of the first shaft about the bearing.Type: ApplicationFiled: May 25, 2018Publication date: May 13, 2021Inventors: Yossi BAR-EL, Gil YIGAL, Reuven Y. FILMAN
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Patent number: 10960131Abstract: An assembly of a drug delivery system, comprising: a first component; a second component which is configured to move linearly with respect to the first component; and, a resistance element configured to resist linear movement during transport of the first component with respect to the second component in a closed transport configuration but which is adapted to be overcome during nominal operation of the drug delivery system.Type: GrantFiled: March 17, 2017Date of Patent: March 30, 2021Assignee: WEST PHARMA. SERVICES IL, LTD.Inventors: Oz Cabiri, Reuven Y. Filman, Yossi Bar-El
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Patent number: 10758679Abstract: A cartridge interface assembly drives a stopper in a drug reservoir or a drug delivery device. An anti-rotational guide optionally moves along an axis of a cavity of the reservoir. The anti-rotational guide is optionally slidably anti-rotationally coupled to a housing of the drug delivery device. A telescoping plunger driver may include a proximal shaft and distal shaft that telescope by relative rotation. The distal shaft is optionally slidably anti-rotationally coupled to the anti-rotational guide. The shafts are optionally oriented along said axis. In some embodiments, rotating the proximal shaft with respect to the anti-rotational guide moves the guide along said axis with respect to the housing and moves the distal shaft along the axis with respect to the anti-rotational guide.Type: GrantFiled: December 4, 2018Date of Patent: September 1, 2020Assignee: WEST PHARMA. SERVICES IL, LTD.Inventors: Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Publication number: 20200254185Abstract: An injector includes an injector housing, an activation button assembly movably mounted to the injector housing and operatively connected to the injection needle, and a cartridge door movably mounted to the injector housing between an open position and a closed position. A deflectable interference member engaging the rear end flange of the cartridge has a resting position configured to limit an insertion depth of a cartridge into an interior channel of the cartridge door to a sealed position, wherein the cartridge piercing needle does not fully penetrate a pierceable septum of the cartridge. The cartridge door includes an interior channel having a cartridge mounted therein. The cartridge includes a substance to be dispensed. The substance includes an anti-C5 antibody or antigen binding fragment thereof, and optionally further includes a recombinant human hyaluronidase enzyme. A method of treating a complement associated condition using an injector thereof.Type: ApplicationFiled: January 31, 2020Publication date: August 13, 2020Inventors: Yossi BAR-EL, Gil YIGAL, Reuven Y. FILMAN
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Publication number: 20200238012Abstract: An injector includes an injector housing, an activation button assembly translatable from an unactuated position to an actuated position and a cartridge door movably mounted to the injector housing between an open position and a closed position. A deflectable interference member has a resting position configured to limit an insertion depth of a cartridge into an interior channel of the cartridge door to a sealed position, wherein the cartridge piercing needle does not fully penetrate a pierceable septum of the cartridge. Movement of the activation button assembly from the unactuated position to the actuated position thereof, in the closed position of the cartridge door, deflects the interference element out of the resting position thereof, thereby enabling further advancement of the cartridge into the interior channel of the cartridge door to an unsealed position, wherein the cartridge piercing needle fully penetrates the pierceable septum.Type: ApplicationFiled: August 2, 2018Publication date: July 30, 2020Inventors: Yossi BAR-EL, Gil YIGAL, Reuven Y. FILMAN
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Patent number: 10716890Abstract: A method of securing an assembly of a drug delivery system, comprising: configuring at least a first component and a second component of the assembly in a closed configuration ready for placement into the drug delivery system; installing an assembly key including a locking element on the assembly to secure the assembly in said configuration; and, transporting the assembly with the assembly key installed.Type: GrantFiled: November 3, 2016Date of Patent: July 21, 2020Assignee: WEST PHARMA. SERVICES IL, LTD.Inventors: Boris Degtiar, Yossi Bar-El, Reuven Y. Filman
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Patent number: 10420880Abstract: A method of securing an assembly of a drug delivery system, comprising: configuring at least a first component and a second component of the assembly in a closed configuration ready for placement into the drug delivery system; installing an assembly key including a locking element on the assembly to secure the assembly in said configuration; and, transporting the assembly with the assembly key installed.Type: GrantFiled: April 30, 2013Date of Patent: September 24, 2019Assignee: West Pharma. Services IL, Ltd.Inventors: Boris Degtiar, Yossi Bar-El, Reuven Y. Filman
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Patent number: 10398837Abstract: A status of a battery operated infuser may be detected by measuring a controlled input parameter. The measurement may be used to determine a magnitude of the input parameter and a parameter of the control. For example, control of power input to a motor may be by pulse density modulation. An integral of current over time may serve as a measure of current magnitude and pulse density. The result of the integral may be used to determine the status of the injector. The status may include normal functions for example start of pumping and/or malfunctions such as occlusion or drive disengagement.Type: GrantFiled: December 27, 2017Date of Patent: September 3, 2019Assignee: West Pharma. Services IL, Ltd.Inventors: Oz Cabiri, Reuven Y. Filman
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Publication number: 20190201288Abstract: An alignment assembly for a cartridge interface of a drug delivery device is disclosed. The assembly optionally includes a coupling for opening fluid communication between the cartridge and the delivery device. For example, the coupling optionally includes a cannula insertable through a septum of the cartridge. The assembly may include a guide for positioning the cartridge and/or an access channel thereof within a first precision of a loaded position. The assembly optionally includes a cartridge engagement fitting (for example a gripping expander sleeve collar) attached to the coupling. Optionally when the cartridge is engaged to the fitting, the coupling is retained in connection with the access channel to within a second precision. The second precision is optionally higher than the first precision. In some embodiments one or more compliant supports movably retain the fitting oriented to engage the cartridge when the access channel is in the loaded position.Type: ApplicationFiled: March 8, 2019Publication date: July 4, 2019Inventors: Yossi BAR-EL, Tomer SOLOMON, Reuven Y. FILMAN
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Patent number: D882761Type: GrantFiled: July 3, 2019Date of Patent: April 28, 2020Assignee: West Pharma. Services IL, Ltd.Inventors: Oz Cabiri, Reuven Y. Filman, Boris Degtiar, Ofer Zick