Patents by Inventor Richard A. Dybas

Richard A. Dybas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060041415
    Abstract: An apparatus, system, and method of simulating communications between a plurality of devices are provided. A series of commands and data block sizes are recorded as trace data by a recording device and stored in a library of trace data. The system functionally includes a first device and a second device, the second device being the device under test. The first device can be replaced by an apparatus that simulates the communications of the first device with the second device. The simulator recreates the commands of the first device by accessing the prerecorded trace data. An apparatus, system and method for measuring and analyzing the performance of modifications made to the trace data are also provided.
    Type: Application
    Filed: August 20, 2004
    Publication date: February 23, 2006
    Inventors: Richard Dybas, Robert Long
  • Patent number: 4622330
    Abstract: Novel 3-amino or substituted amino pyrazoles are disclosed as having antiprotozoal and antiparasitic activity in particular anticoccidial activity and are useful for controlling cecal and or intestinal coccidiosis when administered in minor quantities to animals, in particular to poultry usually in admixture with animal sustenance.
    Type: Grant
    Filed: June 19, 1984
    Date of Patent: November 11, 1986
    Assignee: Merck & Co., Inc.
    Inventors: Richard J. Bochis, Richard A. Dybas, Edward F. Rogers
  • Patent number: 4560677
    Abstract: There is disclosed a novel combination of avermectin compounds and agricultural spray oil which has been found to be synergistic in such a manner as to allow for a drastic reduction in the amount of active ingredient which is fully effective and also a dramatic extension of the time period over which such a combination is fully effective. The synergistic combination is useful as an agricultural insecticide and miticide against a variety of insects and mites which infest a variety of plants.
    Type: Grant
    Filed: January 31, 1984
    Date of Patent: December 24, 1985
    Assignee: Merck & Co., Inc.
    Inventor: Richard A. Dybas
  • Patent number: 4431655
    Abstract: 2,4-Disubstituted-1,2,5-thiadiazol-3(2H)-one antimicrobials have broad spectrum antibacterial and antifungal activity. They are found to be especially useful in agriculture to protect plants against diseases such as leaf, stem, and fruit spotting, internal discoloration and decay of fruits and vegetables. These compounds are particularly active against diseases caused by the genera Pseudomonas, Xanthomonas, Erwinia, and Corynebacterium.
    Type: Grant
    Filed: July 12, 1982
    Date of Patent: February 14, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Richard A. Dybas, Bruce E. Witzel, Nathaniel Grier
  • Patent number: 4402959
    Abstract: Antimicrobial compositions for use in agriculture and methods of treatment are disclosed. The compounds are 3-amino-5,6-dihalopyrazine-2-carbonitrile.
    Type: Grant
    Filed: November 25, 1981
    Date of Patent: September 6, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4391812
    Abstract: Antimicrobial agents suitable for use in aqueous systems for their preservation against biodeterioration include substitutedpiperidinomethylpropenenitriles and propanenitriles. The unsaturated compounds are prepared by reaction of a suitable piperidine with cyano acetic acid and formaldehyde: the propane derivatives therefrom by nucleophilic addition.
    Type: Grant
    Filed: March 24, 1982
    Date of Patent: July 5, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Richard A. Dybas, Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4362877
    Abstract: 2,4-Disubstituted-1,2,5-thiadiazol-3(2H)-one antimicrobials have broad spectrum antibacterial and antifungal activity. They are found to be especially useful in agriculture to protect plants against diseases such as leaf, stem, and fruit spotting, internal discoloration and decay of fruits and vegetables. These compounds are particularly active against diseases caused by the genera Pseudomonas, Xanthomonas, Erwinia, and Corynebacterium.
    Type: Grant
    Filed: April 21, 1980
    Date of Patent: December 7, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Richard A. Dybas, Bruce E. Witzel, Nathaniel Grier
  • Patent number: 4342872
    Abstract: Antimicrobial agents suitable for use in aqueous systems for their prservation against biodeterioration include substitutedpiperidinomethylpropenenitriles and propanenitriles. The unsaturated compounds are prepared by reaction of a suitable piperidine with cyano acetic acid and formaledehyde: the propane derivatives therefrom by nucleophilic addition.
    Type: Grant
    Filed: October 6, 1980
    Date of Patent: August 3, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4342873
    Abstract: Antimicrobial agents suitable for use in aqueous systems for their preservation against biodeterioration include substitutedpiperidinomethyl-propenenitriles and propanenitriles. The unsaturated compounds are prepared by reaction of a suitable piperidine with cyano acetic acid and formaldehyde: the propane derivatives therefrom by nucleophilic addition.
    Type: Grant
    Filed: January 26, 1981
    Date of Patent: August 3, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4340756
    Abstract: Novel halophenyl and loweralkyl substituted halophenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity, and as such are advantageously included as the active agent in surgical scrubs, antibacterial soaps, as preservatives in cosmetic preparations, and the like.
    Type: Grant
    Filed: February 4, 1981
    Date of Patent: July 20, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Richard A. Dybas, Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4339453
    Abstract: 4-Amino- and 2,4-diaminopyrimidines with a quaternized ring nitrogen and an oxygen bearing substituent such as hydroxyalkyl, alkoxyalkyl, or alkanoyl on one of the exo- or endocyclic nitrogens and a C.sub.6-18 alkyl on another, are highly active antimicrobial agents with a relatively low acute mammalian toxicity.
    Type: Grant
    Filed: July 23, 1979
    Date of Patent: July 13, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Elbert E. Harris, Henry Joshua, Arthur A. Patchett, Bruce E. Witzel, Richard A. Dybas
  • Patent number: 4335141
    Abstract: 2-Substituted-aminopropene and propanenitriles of the formula: ##STR1## are effective antimicrobial agents (compounds of Formula II.), and potent anti-inflammatory agents of decreased acute toxicity (compounds of Formula I.).
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: June 15, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4316903
    Abstract: Compounds of the structure: ##STR1## where A is either ##STR2## where R.sub.1 to R.sub.4 are various substituents are active as antibacterials and antifungals.
    Type: Grant
    Filed: May 5, 1978
    Date of Patent: February 23, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4311709
    Abstract: Loweralkyl substituted diphenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity. One particular compound, 1-amino-3-{{3-[4-(1-methylethyl)-phenyl]-1-{2-[4-(methylethyl)-phenyl]ethy l}propyl}amino}-2-propanol, and salts thereof is particularly useful as an udder wash and teat dip for mastitis prevention in lactating cows. Compositions for such use are disclosed.
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: January 19, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Richard A. Dybas, Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4273781
    Abstract: A method of treating pain, fever, and inflammation and pharmaceutical compositions for use therein, wherein the active ingredient comprises a compound of the formula; ##STR1##
    Type: Grant
    Filed: July 17, 1980
    Date of Patent: June 16, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4260760
    Abstract: Novel diphenyl and loweralkyl substituted diphenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity, and as such are advantageously included as the active agent in surgical scrubs, antibacterial soaps, as preservatives in cosmetic preparations, and the like. They also can be used for topical treatment of dermatological conditions having a bacterial origin or implication such as Acne vulgaris.
    Type: Grant
    Filed: March 12, 1979
    Date of Patent: April 7, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Richard A. Dybas, Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4254131
    Abstract: A method of treating pain, fever, and inflammation and pharmaceutical compositions for use therein, wherein the active ingredient comprises a compound of the formula: ##STR1## wherein A and R.sub.1 represent various substituents.
    Type: Grant
    Filed: August 21, 1979
    Date of Patent: March 3, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4250184
    Abstract: A method of treating pain, fever, and inflammation and pharmaceutical compositions for use therein, wherein the active ingredient comprises a compound of the formula; ##STR1##
    Type: Grant
    Filed: July 20, 1979
    Date of Patent: February 10, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4247700
    Abstract: Antimicrobial agents suitable for use in aqueous systems for their preservation against biodeterioration include substitutedpiperidinomethyl-propenenitriles and propanenitriles. The unsaturated compounds are prepared by reaction of a suitable piperidine with cyano acetic acid and formaldehyde: the propane derivatives therefrom by nucleophilic addition. spThis application is a continuation-in-part of Ser. No. 795,693, filed May 11, 1977, now abandoned.
    Type: Grant
    Filed: February 5, 1979
    Date of Patent: January 27, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4244963
    Abstract: 1-[2-(Alkyl and arylsulfonyl)-2-propenyl and propyl] substituted piperidines of the formula: ##STR1## where A is ##STR2## and R.sub.1 -R.sub.5 are various substituents, are useful as antimicrobial and anti-inflammatory agents.
    Type: Grant
    Filed: September 27, 1979
    Date of Patent: January 13, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel