Patents by Inventor Richard A. Mueller

Richard A. Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6248775
    Abstract: &agr;- and &bgr;-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: April 8, 1999
    Date of Patent: June 19, 2001
    Assignee: G. D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, John N. Freskos, Deborah E. Bertenshaw, Robert M. Heintz
  • Patent number: 6211176
    Abstract: &agr;- and &bgr;-amino acid hydroxyethylamino sulfonyl urea derivative compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: April 3, 2001
    Assignee: G. D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, Eric T. Sun
  • Patent number: 6180646
    Abstract: N-heterocyclic moiety containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: January 30, 2001
    Assignee: Monsanto Company
    Inventors: John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, Kathryn L. Reed, Ko-Chung Lin, John Nicholas Freskos, Michael Clare, Donald Joseph Rogier, Jr., Robert M. Heintz, Michael L. Vazquez, Richard A. Mueller
  • Patent number: 6172082
    Abstract: &agr;- and &bgr;-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 9, 2001
    Assignee: G. D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel Getman, Gary A. DeCrescenzo, John N. Freskos
  • Patent number: 6156768
    Abstract: Certain Alpha- and Beta-amino acid hydroxyethylamino sulfamic acid derivatives represented by the following formula are useful as retroviral protease inhibitors: ##STR1##
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: December 5, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Michael L Vazquez, Richard A Mueller, John J Talley, Daniel P Getman, Gary A DeCrescenzo, Eric T Sun
  • Patent number: 6147117
    Abstract: Sulfonamide-containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: July 13, 1999
    Date of Patent: November 14, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel Getman, Gary A. DeCrescenzo, John N. Freskos
  • Patent number: 6066197
    Abstract: A coating composition for use in protecting metal, and for use as a soldering flux, and methods involving the same. A coating for circuit boards and processes involving the same. One coating material can serve as a metal corrosion inhibitor, a no-clean soldering flux, and/or a protective coating in replacement of a conformal coating. In its most preferred form, this invention serves all three functions in the manufacture of an electrical circuit board.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: May 23, 2000
    Assignee: Delphi Technologies, Inc.
    Inventors: Samuel Victor Bristol, Eugene Horace Hanaway, Thomas Richard Mueller, Mary Jane Barnaby
  • Patent number: 6060476
    Abstract: .alpha.- and .beta.-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: March 2, 1994
    Date of Patent: May 9, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel P Getman, Gary A. DeCrescenzo, John N. Freskos, Robert M. Heintz, Deborah E. Bertenshaw
  • Patent number: 6048830
    Abstract: A laundry agent delivery particle is provided. The particle comprises: a) a porous carrier selected from the group consisting of Zeolite X, Zeolite Y and mixtures thereof, the porous carrier including a number of pore openings; and b) a release barrier having at least one deliverable agent residue and at least one size enlarging agent residue, the deliverable agent residue being incorporated into the porous carrier, the size enlarging agent residue having a hydrophilic portion and a hydrophobic portion, the hydrophilic portion incorporated into the porous carrier and in conjunction with the deliverable agent residue forming the release barrier wherein the cross-sectional area of the release barrier within the porous carrier is larger than the cross-sectional area of the pore openings of the porous carrier. Preferred size enlarging agents include those having a fatty chain or alcohol chain in the hydrophobic portion, such as nonionic surfactants.
    Type: Grant
    Filed: September 22, 1998
    Date of Patent: April 11, 2000
    Assignee: The Procter & Gamble Company
    Inventors: Lois Sara Gallon, William Richard Mueller, Robert Ya-Lin Pan
  • Patent number: 6046190
    Abstract: The invention relates to sulfonamide-containing hydroxyethylamine protease inhibitor compounds, their process of making, composition and method of use for inhibiting retroviral proteases such as human immunodeficiency virus.
    Type: Grant
    Filed: January 24, 1996
    Date of Patent: April 4, 2000
    Assignee: G.D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, John N. Freskos, Deborah E. Bertenshaw, Robert M. Heintz
  • Patent number: 6022994
    Abstract: Succinoylamino hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: February 8, 2000
    Assignee: G. D. Searle &. CO.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel Getman, Gary A. DeCrescenzo, John N. Freskos
  • Patent number: 6022996
    Abstract: A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: February 8, 2000
    Assignee: G. D. Searle & Co.
    Inventors: John S. Ng, Claire A. Przybyla, Richard A Mueller, Michael L. Vazquez, Daniel P. Getman
  • Patent number: 6022872
    Abstract: .alpha.- and .beta.-amino acid hydroxyethylamino sulfonyl urea derivative compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: September 6, 1996
    Date of Patent: February 8, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, Eric T. Sun
  • Patent number: 5998685
    Abstract: A highly flexible process for preparing butene oligomers from field butanes. The process can be controlled to produce the desired oligomerization products by appropriate selection of the starting materials.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: December 7, 1999
    Assignee: Huels Aktiengesellschaft
    Inventors: Franz Nierlich, Paul Olbrich, Wilhelm Droste, Richard Mueller, Walter Toetsch
  • Patent number: 5994601
    Abstract: A process is described in which butene oligomers are prepared from Fischer-Tropsch olefins, in which the butenes present in a C.sub.4 fraction of Fischer-Tropsch hydrocarbons are oligomerized to obtain dibutene. The dibutene can be fractionated in a fine distillation stage into di-n-butene and di-isobutene. In one embodiment of the process, the ethylene present in the Fischer-Tropsch olefins is dimerized and the dimerization mixture is recycled to the C.sub.4 fraction. In another embodiment, the isobutene present in the C.sub.4 fraction is reacted with an alcohol to give an alkyl tert-butyl ether, and only the remaining n-butene is oligomerized so that di-n-butene is formed as the sole dibutene.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: November 30, 1999
    Assignee: Huels Aktiengesellschaft
    Inventors: Franz Nierlich, Walter Toetsch, Paul Olbrich, Wilhelm Droste, Richard Mueller
  • Patent number: 5981580
    Abstract: Novel derivatives of fatty acid analogs that have from one to three heteroatoms in the fatty acid moiety which can be oxygen, sulfur or nitrogen, are disclosed in which the carboxy-terminus has been modified to form various amides, esters, ketones, alcohols, alcohol esters and nitrites thereof, and are useful as substrates for N-myristoyltransferase (NMT) and/or its acyl coenzyme, as anti-viral and anti-fungal agents or pro-drugs of such agents.
    Type: Grant
    Filed: October 20, 1998
    Date of Patent: November 9, 1999
    Assignee: G. D. Searle & Co.
    Inventors: Sean T. Nugent, Richard A. Mueller
  • Patent number: 5968942
    Abstract: .alpha.- and .beta.-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: August 23, 1994
    Date of Patent: October 19, 1999
    Assignee: G. D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, John N. Freskos, Deborah E. Bertenshaw, Robert M. Heintz
  • Patent number: 5965588
    Abstract: Sulfonamide-containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: October 12, 1999
    Assignee: G.D. Searle & Co.
    Inventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel Getman, Gary A. DeCrescenzo, John N. Freskos
  • Patent number: 5952377
    Abstract: Novel derivatives of fatty acid analogs that have from one to three heteroatoms in the fatty acid moiety which can be oxygen, sulfur or nitrogen, are disclosed in which the carboxy-terminus has been modified to form various amides, esters, ketones, alcohols, alcohol esters and nitriles thereof, and are useful as substrates for N-myristoyltransferase (NMT) and/or its acyl coenzyme, as anti-viral and anti-fungal agents or pro-drugs of such agents.
    Type: Grant
    Filed: October 20, 1998
    Date of Patent: September 14, 1999
    Assignee: G. D. Searle & Co.
    Inventors: Sean T. Nugent, Richard A. Mueller
  • Patent number: 5948790
    Abstract: N-heterocyclic moiety containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: September 7, 1999
    Assignee: Mosanto Company
    Inventors: John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, Kathryn L. Reed, Ko-Chung Lin, John Nicholas Freskos, Michael Clare, Donald Joseph Rogier, Jr., Robert M. Heintz, Michael L. Vazquez, Richard A. Mueller