Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-readable media, for workflow generation using multiple interfaces. In some implementations, an interface for defining a workflow having one or more operations for a computer system to perform is provided. The interface can provide options that are selectable to cause an operation from a predetermined set of operations to be added to the workflow. Data indicating user selection of an option of the interface corresponding to a first operation in the predetermined set of operations is received. Code that specifies one or more custom operations is received. The workflow is defined to include (i) the first operation based on the data indicating the user selection and (ii) a second operation specified by the code.

Abstract: An assembly for a closure device includes a cap with a distal portion having a recess to receive tissue and a proximal portion fitting over a face of an endoscope. The proximal portion includes fold(s) between a first region and a first end of a second region. The cap expands from a collapsed state in which an angle of the first region relative to a longitudinal axis of the endoscope is at a minimum to an expanded state in which the angle is increased. Based on the angle and reflectivity of the first region, an endoscopic camera on the face is provided an increased field of view in the expanded state relative to the collapsed state. The device captures tissue when the cap is in the expanded state via an actuation mechanism extending through a channel of the endoscope into the distal portion.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: Systems and methods are provided for locating a pair of components relative to one another using complex surfaces. One component has a complex surface, where the complex surface is smoothly contoured. Another component is shaped to be connected with the first component. A fixture locates the first component relative to the second component. The fixture includes a locator with a complex surface region shaped to mate with the complex surface of the one component to locate the fixture relative to that component. The fixture includes another locator to locate the fixture relative to the second component.

Abstract: System and methods are disclosed to promote safe shoving movements of a train based on train position localization without human-based track operations monitoring. Train position detectors deployed at the end of a track, in parallel to the track, between the rails of the track, or a combination thereof, localize an end-of-train during shoving movements. Each train position detector transmits an early warning alert to an onboard alert device and a handheld alert device for indicating the end of the train is about to enter a pre-configured prohibited zone. The locomotive operator receives the alert on the onboard alert device while workers in the railyard receive the alert on the handheld alert devices. Both onboard and handheld alert devices are capable of generating audio, visual, haptic, or a combination of these warning alerts for the locomotive operator and the workers in the railyard.

Abstract: At least one example embodiment provides a non-combustible smoking system or kit, comprising: a cartridge having a first end and a second end; and a tobacco containing section having a third end and a fourth end. The cartridge includes: a pre-vapor formulation reservoir element and a pre-vapor heating element coupled to the pre-vapor formulation reservoir element. The tobacco containing section includes a tobacco housing and a tobacco heating element. The first end of the cartridge is configured to be connected to the fourth end of the tobacco containing section, and the second end of the cartridge is configured to be connected to the third end of the tobacco containing section.

Abstract: This technology relates to providing a web-based digital claims platform to provide users with a simple and customized experience when filing insurance claims. The platform is enabled by a plurality of back-end application programming interface (API) resources. These API resources are event-driven (e.g., when an “event” associated with the claim occurs, the status of the claim changes and the API is provided with updated information indicative of the change). The platform includes a customized user interface (UI) that tailors the claim experience to a particular user's needs. The customization can be based off of stated user preferences and/or learned user preferences associated with the user's past behavior. A user can perform/request various services through the customized UI's self-service function (e.g., rent a car, find a hotel room, select a repair shop, etc.). Additionally, the customized UI can enable the user upload documents, track claim status, find relevant help topics, etc.

Abstract: The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.

Abstract: A method of data transfer from a tenant to a service provider comprises encrypting the data with a public key of a key pair generated by a secure device within the service provider system. The data thus cannot be accessed by the service provider during transmission. The data is generated with a corresponding access control list, which specifies that a valid certificate must be presented in order to grant a particular use of the data once stored. The tenant can thus retain control of the use of the data even though it has been transferred out of the tenant system. A method of controlling use of data securely stored in the service provider system comprises issuing a use certificate having an expiry time to the party requesting use of the data. The use certificate must be validated before use of the stored data is granted. This enables the tenant to grant use of the stored data for a limited time period.

Abstract: There is disclosed a mooring, marine, subsea, underwater or offshore connector (5) comprising: a first portion (10); a second portion (15); and an arrangement (20) for releasably locking the first portion (10) and the second portion (15), wherein the releasable lock arrangement (20) comprises at least one movable lock member (25) which is biased towards a first position. The/each lock member (25) is movable against the action of a biasing arrangement (20) by insertion of the first portion (10) into the second portion (15) and/or by removal of the first portion (10) from the second portion (15). The connector (5) comprises an arrangement for rotating the first portion (10) relative to the second portion (15) when the first portion (10) is inserted into and/or withdrawn from the second portion (15).

Abstract: A combination of a pullback adaptor and a drill bit includes a pullback adaptor having a first end, a second end, a body extending between the first end and the second end, and a protrusion extending from the body adjacent the second end. The protrusion has a threaded aperture defining an adaptor mounting axis, and the protrusion defines an annular planar mount surface generally perpendicular to the adapter mounting axis. A drill bit has a body with a steering surface, an aperture extending through the body at the steering surface, and an adaptor mount surface adjacent the aperture. The pullback adaptor is mounted to the drill bit with a fastener that extends through the aperture in the drill bit and into the threaded aperture of the pullback adaptor such that the annular planar mount surface of the protrusion engages the mount surface of the drill bit.

Abstract: A crossbow de-cocking mechanism may include a trigger mechanism, a trigger latch mechanism and a winch assembly. A first rotational input to the winch may move a trigger latch to disengage the trigger mechanism. A second rotational input to the trigger latch, opposite to the first, may move the trigger mechanism to move a crossbow bowstring from a cocked position to an un-cocked position.

Abstract: A fluid cooled mold plate is disclosed. The fluid cooled mold plate has a front side, a rear side, and a perimeter that extends between its front and rear sides. A cooling chamber is formed within the mold plate. The cooling chamber has a front wall, a rear wall, and a perimeter wall that extends between the front and rear walls. An inlet fluid duct extends from a first side of the mold plate perimeter to a first end of the cooling chamber and an outlet fluid duct extends from a second side of the mold plate perimeter to a second end of the cooling chamber. The cooling chamber is occupied by a turbulence generating dispersion mesh that is secured between the front and rear walls the cooling chamber.

Abstract: A reamer for drill string pullback of a horizontal directional drill includes a shaft portion defining a central axis and a first end configured for attachment with a drill string of the horizontal directional drill. A plurality of vanes extend radially from an outer periphery of the shaft, each of the plurality of vanes defining an outer peripheral tooth base surface. On each of the plurality of vanes, a plurality of cutter teeth are individually and removably secured along the outer peripheral tooth base surface thereof, each one of the plurality of cutter teeth including a body and a PDC insert manufactured separately from the body and joined therewith. Each cutter tooth of the plurality is coupled to the respective one of the plurality of vanes by a removable fastener extending at least partially through the cutter tooth and at least partially through the one of the plurality of vanes.

Abstract: The present invention relates to compounds Formula (I): wherein Q, R2, R3, R4 and R5 are as defined herein. The invention further relates to compositions comprising said compounds, and methods of controlling weeds using said compounds and/or compositions.

Abstract: A computer-implemented method of automatically preserving digital documents stored in a digital preservation system. The method comprises receiving an indication of a change to at least one of configuration data or tools of the digital preservation system, processing the indication to determine at least one affected asset which is stored by the digital preservation system and is affected by the change, determining at least one action to be performed by a tool of the preservation system on the at least one affected asset.

Abstract: An antenna unit includes a case having a base and a lid. An antenna assembly is located within the lid and is IP67 compliant, being waterproof. The antenna assembly can provide antennas located on one or more baseplates that are positioned within the top cover of the box. A baseplate can act as a heatsink, a reflector, and/or a ground plane, for the antennas while the cover is closed and in the locked position. The antennas have been designed and optimized to work on a baseplate and designed to operate with the thick plastic cover of the box. A plurality of antenna components are situated within the base separate from the antenna assembly. An optional barrier is located within the base to divide the antenna components from the lid. The antenna assembly include different types of antennas operable at least between 600 MHz to 39 GHz.

Abstract: Radio frequency (RF) acoustic wave resonator (AWR) filter circuits and methods. Embodiments essentially de-couple the stopband or notch characteristics of an RF filter from the passband characteristics. Accordingly, the de-coupled parameters can be individually designed to meet the specifications of a particular application. Partially-hybridized or fully-hybridized series-arm and parallel-arm AWR filter building blocks enable “de-coupled” RF filters having (1) wideband and low insertion loss passbands and (2) wideband deep notches (stopbands) with a specifically placed notch center frequency, without compromising the passband characteristics. The AWR filter building blocks include an inductance L that matches (resonates with) the electrostatic capacitance CO of the corresponding AWR within a desired passband.